scholarly journals Chemical and Biological Sensors for Time-Series Research: Current Status and New Directions

2004 ◽  
Vol 38 (2) ◽  
pp. 121-143 ◽  
Author(s):  
Kendra L. Daly ◽  
Robert H. Byrne ◽  
Andrew G. Dickson ◽  
Scott M. Gallager ◽  
Mary Jane Perry ◽  
...  

Ocean observatories will require extensive use of sensors and sensing systems to enable time-series observations and interactive experiments on remote permanent and mobile platforms. In this paper we assess the "readiness" of chemical and biological sensors that will be critical to the success of ocean observatories. We conclude that although there have been many technological advances in the development of sensors in recent years, few chemical or biological sensors are capable of long-term deployment (∼ 1 year). In particular, sensors in coastal regions and near hydrothermal vents will need to be regularly serviced for biofouling for the foreseeable future, while sensors on deep-water observatories that spend limited time in the euphotic zone may be able to operate for longer periods. A number of exciting new technologies hold great promise for sensors in the years to come. Significant effort and resources, however, are urgently needed for sensor development to ensure that the opportunities for science and discovery made accessible by ocean observatories are fully realized.

This handbook examines cutting-edge developments in research and applications of small or mesoscopic superconductors, offering a glimpse of what might emerge as a giga world of nano superconductors. Contributors, who are eminent frontrunners in the field, share their insights on the current status and great promise of small superconductors in the theoretical, experimental, and technological spheres. They discuss the novel and intriguing features and theoretical underpinnings of the phenomenon of mesoscopic superconductivity, the latest fabrication methods and characterization tools, and the opportunities and challenges associated with technological advances. The book is organized into three parts. Part I deals with developments in basic research of small superconductors, including local-scale spectroscopic studies of vortex organization in such materials, Andreev reflection and related studies in low-dimensional superconducting systems, and research on surface and interface superconductivity. Part II covers the materials aspects of small superconductors, including mesoscopic effects in superconductor–ferromagnet hybrids, micromagnetic measurements on electrochemically grown mesoscopic superconductors, and magnetic flux avalanches in superconducting films with mesoscopic artificial patterns. Part III reviews the current progress in the device technology of small superconductors, focusing on superconducting spintronics and devices, barriers in Josephson junctions, hybrid superconducting devices based on quantum wires, superconducting nanodevices, superconducting quantum bits of information, and the use of nanoSQUIDs in the investigation of small magnetic systems.


2019 ◽  
Vol 1 (1) ◽  
pp. 199-226
Author(s):  
Ricardo M. Piñeyro Prins ◽  
Guadalupe E. Estrada Narvaez

We are witnessing how new technologies are radically changing the design of organizations, the way in which they produce and manage both their objectives and their strategies, and -above all- how digital transformation impacts the people who are part of it. Even today in our country, many organizations think that digitalizing is having a presence on social networks, a web page or venturing into cases of success in corporate social intranet. Others begin to invest a large part of their budget in training their teams and adapting them to the digital age. But given this current scenario, do we know exactly what the digital transformation of organizations means? It is necessary? Implying? Is there a roadmap to follow that leads to the success of this process? How are organizations that have been born 100% digital from their business conception to the way of producing services through the use of platforms? What role does the organizational culture play in this scenario? The challenge of the digital transformation of businesses and organizations, which is part of the paradigm of the industrial revolution 4.0, is happening here and now in all types of organizations, whether are they private, public or third sector. The challenge to take into account in this process is to identify the digital competences that each worker must face in order to accompany these changes and not be left out of it. In this sense, the present work seeks to analyze the main characteristics of the current technological advances that make up the digital transformation of organizations and how they must be accompanied by a digital culture and skills that allow their successful development. In order to approach this project, we will carry out an exploratory research, collecting data from the sector of new actors in the world of work such as employment platforms in its various areas (gastronomy, delivery, transportation, recreation, domestic service, etc) and an analysis of the main technological changes that impact on the digital transformation of organizations in Argentina.


Author(s):  
Lilian Marques Silva

The almost instantaneous access to information provided by technological advances has revolutionized the behavior of people and of the classrooms too. Teachers had to adapt themselves to new technologies to maintain students interested and attentive to the discipline being taught. In this work, the behavior of the students of the 6th grade of elementary school II during class was observed. The school chosen is a public school in the State of São Paulo (Brazil). The research was based on data collection. The students were observed by being filmed during six months. The results showed that the students were interested in the classes and committed to the activities. The place that the student chooses to sit in the classroom influences the behavior of the teacher, because the more distant the teacher, the less he participates in the class.


Author(s):  
Vladimir I. Karnyshev ◽  
◽  
Vladimir I. Avdzeyko ◽  
Evgenia S. Paskal ◽  
◽  
...  

The forecasting of development trends and the timely revealing of new technical (technological) fields are the key prerequisite for an effective development of modern economy. Only reliable results of technological analysis (forecast) allow identifying new technologies, understanding the evolution of entire industries, carrying out strategic investment planning at the state level, and also planning R&D correctly. The aim of this work is to justify one of the possible approaches to the classification of technical (technological) fields in terms of assessing their relevance, novelty and short-term prospects. This approach is based on patent analysis, in particular, on the study of the time series features of US invention patents (1976-2018) for more than seventy-three thousand main groups (subgroups) of the 17th edition of the International Patent Classification (IPC17). The United States Patent and Trademark Office (USPTO) has been selected as the primary source of information because it is one of the world’s largest and constantly updated patent resources, providing direct access to full-text descriptions. In the authors’ opinion, a feature analysis of the US patent issue dynamics at time intervals (1976-2015, 2009-2018 and 2016-2018) allows dividing the IPC groups (subgroups) into the following three main clusters: “unpromising”, “promising” and “breakthrough”. In terms of the timely revealing of new, previously unknown, technologies or solutions in the technical field, or of the steadily growing technological trends, the “breakthrough” and “promising” subgroups are of the greatest practical interest. The article presents the results of an empirical classification of 71,266 subgroups (with a non-zero number of the issued patents since 1976 to 2018) in eight sections of the IPC17. These data may be useful for developers, researchers and R&D planners in solving complex scientific and technical problems, as well as for making short-term forecast estimates of a specific technical (technological) field development.


2011 ◽  
Vol 135 (7) ◽  
pp. 860-869 ◽  
Author(s):  
Soheil S. Dadras

Abstract Context.—In the current “molecular” era, the advent of technology, such as array-based platforms, systems biology, and genome-wide approaches, has made it possible to examine human cancers, including melanoma, for genetic mutations, deletions, amplification, differentially regulated genes, and epigenetic changes. Advancement in current technologies is such that one can now examine ribonucleic acid (RNA), deoxyribonucleic acid (DNA), and protein directly from the patient's own tumor. Objective.—To apply these new technologies in advancing molecular diagnostics in melanoma has historically suffered from a major obstacle, namely, the scarcity of fresh frozen, morphologically defined tumor banks, annotated with clinical information. Recently, some of the new platforms have advanced to permit utilization of formalin-fixed, paraffin-embedded (FFPE) tumor specimens as starting material. Data Sources.—This article reviews the latest technologies applied to FFPE melanoma sections, narrowing its focus on the utility of transcriptional profiling, especially for melastatin; comparative genomic hybridization; BRAF and NRAS mutational analysis; and micro ribonucleic acid profiling. Conclusion.—New molecular approaches are emerging and are likely to improve the classification of melanocytic neoplasms.


2021 ◽  
Author(s):  
Jiyeon Yu ◽  
Angelica de Antonio ◽  
Elena Villalba-Mora

BACKGROUND eHealth and Telehealth play a crucial role in assisting older adults who visit hospitals frequently or who live in nursing homes and can benefit from staying at home while being cared for. Adapting to new technologies can be difficult for older people. Thus, to better apply these technologies to older adults’ lives, many studies have analyzed acceptance factors for this particular population. However, there is not yet a consensual framework to be used in further development and the search for solutions. OBJECTIVE This paper presents an Integrated Acceptance Framework (IAF) for the older user’s acceptance of eHealth, based on 43 studies selected through a systematic review. METHODS We conducted a four-step study. First, through a systematic review from 2010 to 2020 in the field of eHealth, the acceptance factors and basic data for analysis were extracted. Second, we carried out a thematic analysis to group the factors into themes to propose and integrated framework for acceptance. Third, we defined a metric to evaluate the impact of the factors addressed in the studies. Last, the differences amongst the important IAF factors were analyzed, according to the participants’ health conditions, verification time, and year. RESULTS Through the systematic review, 731 studies were founded in 5 major databases, resulting in 43 selected studies using the PRISMA methodology. First, the research methods and the acceptance factors for eHealth were compared and analyzed, extracting a total of 105 acceptance factors, which were grouped later, resulting in the Integrated Acceptance Framework. Five dimensions (i.e., personal, user-technology relational, technological, service-related, environmental) emerged with a total of 23 factors. Also, we assessed the quality of the evidence. And then, we conducted a stratification analysis to reveal the more appropriate factors depending on the health condition and the assessment time. Finally, we assess which are the factors and dimensions that are recently becoming more important. CONCLUSIONS The result of this investigation is a framework for conducting research on eHealth acceptance. To elaborately analyze the impact of the factors of the proposed framework, the criteria for evaluating the evidence from the studies that have extracted factors are presented. Through this process, the impact of each factor in the IAF has been presented, in addition to the framework proposal. Moreover, a meta-analysis of the current status of research is presented, highlighting the areas where specific measures are needed to facilitate e-Health acceptance.


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