scholarly journals Current Clinical Concepts: Clinical Management of Patellar Tendinopathy

2021 ◽  
Author(s):  
Adam B. Rosen ◽  
Elizabeth Wellsandt ◽  
Mike Nicola ◽  
Matthew A. Tao
Keyword(s):  
Effective Treatment ◽  
Clinical Management ◽  
Management Strategies ◽  
Treatment Strategies ◽  
Patellar Tendinopathy ◽  
Load Management ◽  
Evidence Based ◽  
Effective Treatment Option ◽  
Treatment Interventions

ABSTRACT Patellar tendinopathy is a common, yet misunderstood pathoetiology afflicting a variety of patient populations. This lack of unified understanding affects the capability of clinicians to provide effective treatment interventions. Patients with tendinopathy often report long-term and low to moderate levels of pain, diminished flexibility, and strength, as well as decreased physical function. Load-management strategies combined with exercise regimens focused on progressive tendon loading are the most effective treatment option for patients with patellar tendinopathy. This review will provide an evidence-based approach to patellar tendinopathy, including its pathoetiology, evaluation, and treatment strategies.

scholarly journals Crowdfunding Cannabidiol (CBD) for Cancer: Hype and Misinformation on GoFundMe

2020 ◽  
Vol 110 (S3) ◽  
pp. S294-S299
Author(s):  
Marco Zenone ◽  
Jeremy Snyder ◽  
Timothy Caulfield
Keyword(s):  
Public Health ◽  
Pain Management ◽  
Effective Treatment ◽  
Treatment Option ◽  
Adverse Impact ◽  
Evidence Based ◽  
Sources Of Information ◽  
Effective Treatment Option ◽  
Health Implications

Objectives. To use crowdfunding campaigns to better understand how cannabidiol (CBD) is represented (and misrepresented) as cancer-related care. Methods. We analyzed CBD-related crowdfunding campaigns (n = 155) created between January 2017 and May 2019 in multiple countries on GoFundme.com . Results. More than 81.9% of campaigns fundraised CBD for curative or life-prolonging reasons, and 25.2% fundraised for pain management. Conclusions. Most campaigns seeking funds for CBD for cancer-related care on GoFundMe are for curative or life-prolonging purposes and present CBD definitively as an effective treatment option. In general, campaigners supported their funding requests with anecdotal claims of efficacy and referenced sources of information that were either not evidence-based or that misrepresented existing evidence. Public Health Implications. Misinformation around CBD for cancer is widespread on medical crowdfunding campaigns. Given the potential adverse impact, crowdfunding platforms, like GoFundMe, must take steps to address their role in enabling and spreading this misinformation.

scholarly journals Balloon dilation for the treatment of nasopharyngeal stenosis in seven cats

2017 ◽  
Vol 3 (2) ◽  
pp. 205511691772998
Author(s):  
Stefeny Z Pollack ◽  
Peter S Chapman ◽  
Alan Klag
Keyword(s):  
Effective Treatment ◽  
Medical Records ◽  
Balloon Dilation ◽  
Clinical Signs ◽  
Upper Airway ◽  
Short Term ◽  
Effective Treatment Option ◽  
Endoscopic Guidance ◽  
Ocular Discharge

Objectives The objective of this study was to evaluate the effectiveness of balloon dilation for the treatment of nasopharyngeal stenosis in cats. Methods The medical records of seven cats with nasopharyngeal stenosis treated with balloon dilation were reviewed. The most common presenting clinical signs included upper airway noise, sneezing, nasal and/or ocular discharge. All seven cats were confirmed to have nasopharyngeal stenosis via nasopharyngeal endoscopy and were treated with balloon dilation under endoscopic guidance. Results All seven cats had acceptable short-term control (median 14 days) of clinical signs after the procedure. Two of six cats had successful long-term control (median 34 days) of clinical signs after one balloon dilation and an additional 2/6 cats had acceptable long-term control of clinical signs after a second balloon dilation procedure. The most significant complication of balloon dilation was the recurrence of stenosis. Conclusions and relevance The findings of this study indicate that balloon dilation is a safe and effective treatment option for the relief of clinical signs associated with nasopharyngeal stenosis in cats. Multiple procedures may be necessary for the best chance of long-term success.

Central Neurocytoma

Neurosurgery ◽  
2012 ◽  
Vol 72 (3) ◽  
pp. 407-414 ◽  
Author(s):  
Jin Wook Kim ◽  
Dong Gyu Kim ◽  
In Kyeong Kim ◽  
Yong Hwy Kim ◽  
Seung Hong Choi ◽  
...  
Keyword(s):  
Overall Survival ◽  
Clinical Outcomes ◽  
Functional Outcomes ◽  
Management Strategies ◽  
Treatment Strategies ◽  
Central Neurocytoma ◽  
Tumor Control ◽  
Seizure Outcome

Abstract BACKGROUND: A thorough investigation of the long-term outcomes of central neurocytoma (CN) after different treatments is required to establish optimal management strategies. OBJECTIVE We retrospectively reviewed the long-term clinical outcomes of patients with CN according to various treatments and suggest treatment strategies based on 30 years of experience in a single institution. METHODS: Fifty-eight consecutive patients with CN were treated at our institution between 1982 and 2008. Patient demographics, overall survival, local control rates according to multimodal treatments, and functional outcomes were evaluated. The mean clinical and radiological follow-up periods were 119 months (range, 18-304 months) and 98 months (range, 13-245 months), respectively. RESULTS: The initial treatment modality was classified into 4 subgroups: operation only (34 patients), operation followed by radiation therapy (7 patients) or radiosurgery (7 patients), and radiosurgery alone (10 patients). The actuarial overall survival was 91% at 5 years and 88% at 10 years. The actuarial overall survival and local tumor control rate did not differ significantly according to the various treatments and the initial extent of the surgical resection. However, functional outcomes, such as the postoperative seizure outcome at the last follow-up, differed according to the surgical approach. CONCLUSION: The long-term clinical outcomes of CN after multimodal treatment seem to be excellent. Our study suggests that treatment strategies for CN should focus on the patient's quality of life, as well as on tumor control, because of the benign nature of CN.

Entrapment syndromes

2019 ◽  
pp. 839-846
Author(s):  
Grainne Bourke ◽  
Mobin Syed
Keyword(s):  
Peripheral Nerve ◽  
Effective Treatment ◽  
Carpal Tunnel ◽  
Carpal Tunnel Release ◽  
Management Strategies ◽  
Treatment Strategies ◽  
Nerve Entrapment ◽  
Cubital Tunnel ◽  
Meralgia Paraesthetica ◽  
Entrapment Syndromes

Peripheral nerve entrapment is common. Patients present with tingling and pain in the distribution of the affected nerve. This will progress to altered sensation and weakness with prolonged and/or increasing pressure. The most common nerve entrapment syndromes are carpal tunnel affecting the median nerve at the wrist and cubital tunnel affecting the ulnar nerve at the elbow. They affect the working population, so time-efficient diagnosis and robust effective treatment strategies are important to minimize the financial implications to industry. Aetiology, diagnosis, and management strategies for carpal tunnel, cubital tunnel, and meralgia paraesthetica are discussed in this chapter along with a brief overview of other entrapment syndromes. Current controversies between open and endoscopic carpal tunnel release are also reviewed.

Cervical Radiculopathy

2018 ◽  
pp. 231-236
Author(s):  
Samuel W. Samuel ◽  
Eduardo E. Icaza
Keyword(s):  
Conservative Management ◽  
Treatment Strategies ◽  
Cervical Radiculopathy ◽  
Surgical Decompression ◽  
Evidence Based ◽  
Long Term Outcomes ◽  
Painful Condition ◽  
Surgical Treatments ◽  
Cervical Root

This chapter discusses cervical radiculopathy, a common, painful condition from cervical root compression, irritation, or both. A thorough history and physical exam can often help in diagnosing the affected nerve root, without the need for reflexive imaging. A series of provocative tests can aid in the differential diagnosis. Most cases will be resolved with conservative management within several weeks of symptoms onset. Evidence-based conservative management includes physical therapy and oral NSAIDs. If symptoms indicate myelopathic changes or are refractory to 6 to 8 weeks of conservative management, advanced imaging such as MRI should be considered. Patients with imaging evidence of a compressive etiology and refractory to conservative therapy should have a surgical consultation. Either an MRI or CT should be obtained before surgical decompression. Both interventional and surgical treatments have had positive outcomes in the short term, but long-term outcomes appear comparable to those with conservative therapies. It is recommended that conservative treatment strategies be used for 6–8 weeks before pursuing procedural or surgical intervention.

scholarly journals Parkinsonism in the psychiatric setting: an update on clinical differentiation and management

2020 ◽  
Vol 2 (1) ◽  
pp. e000034
Author(s):  
Alice Powell ◽  
Lara Gallur ◽  
Leslie Koopowitz ◽  
Michael William Hayes
Keyword(s):  
Drug Exposure ◽  
Management Strategies ◽  
Treatment Strategies ◽  
Extensive Literature ◽  
Duration Of Treatment ◽  
Drug Induced ◽  
Psychiatric Setting ◽  
Psychiatric Conditions ◽  
Long Term Prognosis

Parkinsonism is seen frequently in patients with psychiatric conditions. Drug-induced parkinsonism (DIP) is the second most common cause of parkinsonism in the general population after Parkinson’s disease (PD) but a range of rarer aetiologies, some of them reversible, should also be considered in patients of all ages. DIP is more common in older patients, as are neurodegenerative diseases that may produce parkinsonism and it is relatively more likely that drug exposure could be unmasking an underlying process in this population. There is an extensive literature on differentiating DIP from PD but clinical features can be indistinguishable and many proposed investigations are not readily available. Aside from cessation of the responsible medication, there is no clear consensus on treatment strategies or duration of treatment. Practically, a delicate balance must be achieved between ameliorating parkinsonism and avoiding recurrent psychosis. Long-term prognosis in the setting of DIP remains unclear. We review the features that may differentiate DIP from other causes of parkinsonism in patients with psychiatric illness, provide an update on relevant investigations and discuss management strategies. The use of atypical antipsychotics for a broad range of indications highlights the ongoing relevance of DIP.

Forecasting Methods in Electric Power Sector

2018 ◽  
Vol 7 (1) ◽  
pp. 1-21 ◽  
Author(s):  
Sujit Kumar Panda ◽  
Alok Kumar Jagadev ◽  
Sachi Nandan Mohanty
Keyword(s):  
Electric Power ◽  
Financial Analysis ◽  
Management Strategies ◽  
Load Forecasting ◽  
Electricity Consumption ◽  
Load Management ◽  
Electrical Load ◽  
Electric Power Sector ◽  
Electrical Load Forecasting

Electric power plays a vibrant role in economic growth and development of a region. There is a strong co-relation between the human development index and per capita electricity consumption. Providing adequate energy of desired quality in various forms in a sustainable manner and at a competitive price is one of the biggest challenges. To meet the fast-growing electric power demand, on a sustained basis, meticulous power system planning is required. This planning needs electrical load forecasting as it provides the primary inputs and enables financial analysis. Accurate electric load forecasts are helpful in formulating load management strategies in view of different emerging economic scenarios, which can be dovetailed with the development plan of the region. The objective of this article is to understand various long term electrical load forecasting techniques, to assess its applicability; and usefulness for long term electrical load forecasting for an isolated remote region, under different growth scenarios considering demand side management, price and income effect.

scholarly journals Molar Incisor Hypomineralization from Inception to Intervention–Evidence Based Review

2021 ◽  
pp. 113-125
Author(s):  
Rana A. Alamoudi
Keyword(s):  
Oral Health ◽  
Wide Spectrum ◽  
Treatment Plan ◽  
Treatment Strategies ◽  
Treatment Modalities ◽  
Evidence Based ◽  
Tailored Treatment ◽  
Dental Practitioners ◽  
Molar Incisor Hypomineralization

Background: Molar Incisor Hypomineralization (MIH) is considered a highly prevalent clinical problem worldwide. The etiology of MIH involves a complex interaction between systemic and environmental insults with possible genetic contribution. Early diagnosis is facilitated by collaboration between clinicians responsible for oral health management of the patient and is the key for enhancing the long-term prognosis and quality of life of affected children. MIH management is a formidable oral health challenge due to the wide spectrum of clinical presentation with the need for tailored treatment for the child affected by MIH condition. Objective: To provide dental practitioners with an updated and evidence-based overview of MIH etiology, diagnosis, and treatments modalities available for its management. Conclusion: In this review, recent clinical evidence on MIH etiology, diagnosis and treatment is presented. Given recent availability of sophisticated technologies there is an increasing number of treatment modalities now at the fingertips of all oral health clinicians alike, ranging from preventive measures, management of hypersensitivity to advanced restorative techniques. The tailored treatment plan should encompass a short and long-term approach requiring more frequent dental check-ups in order to achieve better outcomes and prognosis. Future translational clinical research to best practice that will enhance our understanding of the exact causes of MIH and allow development of standardized diagnostic criteria as well as optimal treatment strategies are warranted.

scholarly journals Obesity 2021: Current Clinical Management of a Chronic, Serious Disease

2021 ◽  
Vol 70 (6 Supplement) ◽  
Author(s):  
Kushner
Keyword(s):  
Early Intervention ◽  
Patient Engagement ◽  
Clinical Management ◽  
Disease Burden ◽  
Management Strategies ◽  
Learning Objectives ◽  
Recommended Care ◽  
Serious Disease ◽  
Term Management

LEARNING OBJECTIVES At the end of the activity, participants will be able to: • Recognize obesity as a chronic, relapsing, serious disease warranting long-term management and early intervention to minimize disease burden and decrease associated morbidity and mortality. • Destigmatize obesity to initiate and enhance patient engagement. • Apply guideline-recommended care for screening, diagnosis, and individualized treatment of adults and others with obesity. • Incorporate practical practice management strategies.

scholarly journals Giant Actinomyces brain abscess in an immunocompetent child: A management strategy

2021 ◽  
Vol 12 ◽  
pp. 325
Author(s):  
Nicole H. Chicoine ◽  
Jackson Griffith-Linsley ◽  
Joling Goh ◽  
John J. Manaloor ◽  
Jeffrey S. Raskin
Keyword(s):  
Brain Abscess ◽  
Medical Management ◽  
Management Strategies ◽  
Treatment Strategies ◽  
Mass Effect ◽  
Needle Aspiration ◽  
Immunocompetent Child ◽  
Long Term Follow Up

Background: Intraparenchymal brain abscess is a collection of microbes caused by inoculation through direct extension or hematogenous spread. Although rare, intraparenchymal abscesses are potentially fatal and can be detected when patients are symptomatic due to local mass effect on adjacent neural tissue. Brain abscess treatment includes medical management with appropriate antibiotics alone or medical management in combination with surgical debridement. Treatment strategies depend on the size and location of disease, as well as the virulence of the microorganism. Similar to medical management strategies, surgical strategies among providers are not uniform, with variation in approaches from complete extirpation of the abscess, including the abscess wall, to minimally invasive stereotactic needle aspiration. In particular, for children, there are no guidelines for therapy. Case Description: We report a case of giant Actinomycosis right frontal brain abscess in an immunocompetent child without risk factors. A review of the literature for the treatment of brain abscess caused very rarely by Actinomyces in children is performed. Conclusion: Successful treatment of brain access depends on organism and location. The even more uncommon giant intraparenchymal abscesses can be managed with minimal access and prolonged antibiosis, especially when slow-growing organisms are identified. Long-term follow-up should be employed to mitigate missed late failures.

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