scholarly journals Current understandings about cognition and the neurobiological correlates in schizophrenia

2016 ◽  
Vol 07 (03) ◽  
pp. 412-418 ◽  
Author(s):  
Sujita Kumar Kar ◽  
Meha Jain
Keyword(s):  
Conceptual Understanding ◽  
Cognitive Deficits ◽  
Processing Speed ◽  
Verbal Fluency ◽  
Clinical Implications ◽  
Severe Mental Disorder ◽  
The Core ◽  
Visuospatial Skills ◽  
Multiple Domains ◽  
Core Features

ABSTRACTSchizophrenia is a severe mental disorder. Cognitive deficits are one of the core features of schizophrenia. Multiple domains of cognition (executive function, attention/vigilance, working memory, verbal fluency, visuospatial skills, processing speed, and social cognition) are affected in patients with schizophrenia. Deficits in cognition led to impairment in the real world functioning. Identifying the cognitive deficits and early intervention is required for better functional outcome. This review focuses on conceptual understanding of cognition with its neurobiological correlates in schizophrenia and its different clinical implications.

Exploring the pattern and neural correlates of neuropsychological impairment in late-life depression

2011 ◽  
Vol 42 (6) ◽  
pp. 1195-1202 ◽  
Author(s):  
C. E. Sexton ◽  
L. McDermott ◽  
U. G. Kalu ◽  
L. L. Herrmann ◽  
K. M. Bradley ◽  
...  
Keyword(s):  
Executive Function ◽  
Episodic Memory ◽  
Cognitive Deficits ◽  
Processing Speed ◽  
Language Skills ◽  
Late Life ◽  
Neural Correlates ◽  
Late Life Depression ◽  
Multiple Domains ◽  
Anterior Thalamic Radiation

BackgroundNeuropsychological impairment is a key feature of late-life depression, with deficits observed across multiple domains. However, it is unclear whether deficits in multiple domains represent relatively independent processes with specific neural correlates or whether they can be explained by cognitive deficits in executive function or processing speed.MethodWe examined group differences across five domains (episodic memory; executive function; language skills; processing speed; visuospatial skills) in a sample of 36 depressed participants and 25 control participants, all aged ⩾60 years. The influence of executive function and processing speed deficits on other neuropsychological domains was also investigated. Magnetic resonance imaging correlates of executive function, processing speed and episodic memory were explored in the late-life depression group.ResultsRelative to controls, the late-life depression group performed significantly worse in the domains of executive function, processing speed, episodic memory and language skills. Impairments in executive function or processing speed were sufficient to explain differences in episodic memory and language skills. Executive function was correlated with anisotropy of the anterior thalamic radiation and uncinate fasciculus; processing speed was correlated with anisotropy of genu of the corpus callosum. Episodic memory was correlated with anisotropy of the anterior thalamic radiation, the genu and body of the corpus callosum and the fornix.ConclusionsExecutive function and processing speed appear to represent important cognitive deficits in late-life depression, which contribute to deficits in other domains, and are related to reductions in anisotropy in frontal tracts.

Verbal fluency in male and female schizophrenia patients: Different patterns of association with processing speed, working memory span, and clinical symptoms.

2018 ◽  
Vol 32 (1) ◽  
pp. 65-76 ◽  
Author(s):  
Gildas Brébion ◽  
Christian Stephan-Otto ◽  
Susana Ochoa ◽  
Lourdes Nieto ◽  
Montserrat Contel ◽  
...  
Keyword(s):  
Working Memory ◽  
Processing Speed ◽  
Verbal Fluency ◽  
Memory Span ◽  
Clinical Symptoms ◽  
Male And Female

Reduced Jumping to Conclusion Bias after Experimentally Induced Enhancement of Subjective Body Boundaries in Psychosis

2021 ◽  
Vol 54 (2) ◽  
pp. 92-97
Author(s):  
Naomi Lyons ◽  
Detlef E. Dietrich ◽  
Johannes Graser ◽  
Georg Juckel ◽  
Christian Koßmann ◽  
...  
Keyword(s):  
Sense Of Self ◽  
Psychotic Symptoms ◽  
Control Group ◽  
Implicit Measure ◽  
Relevant Factor ◽  
The Core ◽  
Significant Difference ◽  
Explicit Measure ◽  
Experimental Group ◽  
Core Features

<b><i>Introduction:</i></b> A disturbed sense of self is frequently discussed as an etiological factor for delusion symptoms in psychosis. Phenomenological approaches to psychopathology posit that lacking the sense that the self is localized within one’s bodily boundaries (disembodiment) is one of the core features of the disturbed self in psychosis. The present study examines this idea by experimentally manipulating the sense of bodily boundaries. <b><i>Methods:</i></b> Seventy-three patients with psychosis were randomly assigned to either a 10-min, guided self-massage in the experimental group (EG) to enhance the sense of bodily boundaries or a control group (CG), which massaged a fabric ring. Effects on an implicit measure (jumping to conclusion bias; JTC) and an explicit measure (Brief State Paranoia Checklist; BSPC) of delusion processes were assessed. The JTC measures the tendency to make a decision with little evidence available, and the BSPC explicitly measures the approval of paranoid beliefs. <b><i>Results:</i></b> Patients in the EG showed a lower JTC (<i>M</i> = 4.11 draws before decision) than the CG (<i>M</i> = 2.43; Cohen’s <i>d</i> = 0.64). No significant difference in the BSPC was observed. <b><i>Discussion/Conclusion:</i></b> Our results indicate that enhancing the sense of body boundaries through a self-massage can reduce an implicit bias associated with delusional ideation and correspondingly support the idea that disembodiment might be a relevant factor in the formation of psychotic symptoms.

scholarly journals The Dynamics of Musical Participation

2021 ◽  
pp. 102986492098831
Author(s):  
Andrea Schiavio ◽  
Pieter-Jan Maes ◽  
Dylan van der Schyff
Keyword(s):  
Dynamical System ◽  
Dynamical Systems ◽  
Systems Theory ◽  
Dynamical Systems Theory ◽  
Coordination Dynamics ◽  
Musical Experience ◽  
The Core ◽  
Interactive Dynamics ◽  
Interdisciplinary Scholarship ◽  
Core Features

In this paper we argue that our comprehension of musical participation—the complex network of interactive dynamics involved in collaborative musical experience—can benefit from an analysis inspired by the existing frameworks of dynamical systems theory and coordination dynamics. These approaches can offer novel theoretical tools to help music researchers describe a number of central aspects of joint musical experience in greater detail, such as prediction, adaptivity, social cohesion, reciprocity, and reward. While most musicians involved in collective forms of musicking already have some familiarity with these terms and their associated experiences, we currently lack an analytical vocabulary to approach them in a more targeted way. To fill this gap, we adopt insights from these frameworks to suggest that musical participation may be advantageously characterized as an open, non-equilibrium, dynamical system. In particular, we suggest that research informed by dynamical systems theory might stimulate new interdisciplinary scholarship at the crossroads of musicology, psychology, philosophy, and cognitive (neuro)science, pointing toward new understandings of the core features of musical participation.

A comparison of cognitive functioning in acute schizophrenia and depression

2013 ◽  
Vol 25 (6) ◽  
pp. 334-341 ◽  
Author(s):  
Tina Gooren ◽  
Peter Schlattmann ◽  
Peter Neu
Keyword(s):  
Major Depression ◽  
Cognitive Deficits ◽  
Verbal Fluency ◽  
Verbal Learning ◽  
Trail Making Test ◽  
Acute Schizophrenia ◽  
Wechsler Memory Scale ◽  
Schizophrenic Patients ◽  
Trail Making ◽  
Unipolar Major Depression

ObjectiveEven though cognitive deficits are well recognised in schizophrenia and depression, direct comparisons between the disorders are scarce in literature. This study aims to assess specificity and degree of cognitive deficits in inpatients with acute schizophrenia and unipolar major depression.MethodsA neuropsychological test battery was administered to 76 schizophrenic patients, 102 patients with unipolar major depression and 85 healthy controls (HCs), assessing verbal learning [Rey Auditory Verbal Learning Test (RAVLT)], processing speed (Trail Making Test), verbal fluency and visual memory (Wechsler Memory Scale-Revised test).ResultsBoth patient groups were significantly impaired compared with HCs with regard to all test outcomes. The schizophrenia group (SG) performed significantly worse in the Wechsler Memory Scale and verbal fluency than the depression group (DG). The DG reached significantly lower scores than the SG in the RAVLT delayed recall subtest. No significant group difference between SG and DG was found for the Trail Making Test and the RAVLT direct recall trails.ConclusionOur results indicate that cognitive impairment is present in both disorders. Schizophrenic patients performed worse than patients with unipolar depression in only two of the administered tests. Differences in cognitive performance between the groups are not as general as often assumed. Therefore, during the acute phase of illness, a diagnostic classification on the grounds of the patients’ neurocognitive performance has to be done with caution.

Test–Retest Reliability of Social Cognition Screening Questionnaire–Taiwan Version in People With Schizophrenia

2021 ◽  
Vol 75 (Supplement_2) ◽  
pp. 7512500023p1-7512500023p1
Author(s):  
Shu-Chun Lee ◽  
Yi-Ching Wu ◽  
David Leland Roberts ◽  
Kuang-Pei Tseng ◽  
Wen-Yin Chen
Keyword(s):  
Social Cognition ◽  
Random Measurement Error ◽  
Good Test ◽  
Retest Reliability ◽  
Screening Questionnaire ◽  
The Core ◽  
Random Measurement ◽  
The Social ◽  
Test Retest Reliability ◽  
Multiple Domains

Abstract Date Presented 04/19/21 The Social Cognition Screening Questionnaire–Taiwan version (SCSQT) was designed to assess multiple domains of social cognition in people with schizophrenia in Taiwan. The SCSQT contains five subscales and provides estimates of the core domains of mentalizing and social perception and an overall social cognition score. Our validation of SCSQT indicated that the SCSQT had good test–retest reliability, acceptable random measurement error, and negligible practice effects. Primary Author and Speaker: Shu-Chun Lee Additional Authors and Speakers: Trudy Mallinson Contributing Authors: Alison M. Cogan, Ann Guernon, Katherine O'Brien, and Piper Hansen

Driving Performance Deficits Despite Concussion Symptom Resolution: A Case Report

2018 ◽  
Vol 23 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Nicole L. Hoffman ◽  
Hannes Devos ◽  
Julianne D. Schmidt
Keyword(s):  
Case Report ◽  
Cognitive Deficits ◽  
Processing Speed ◽  
Driving Simulator ◽  
Driving Performance ◽  
Performance Study ◽  
Male College Student ◽  
Performance Deficits ◽  
Male College ◽  
Complex Attention

Driving performance prior to concussion is not commonly available to help clinicians identify when deficits return to a preinjury status. This case report examines driving performance prior to and following concussion in a 20-year-old male college student. He initially volunteered as a control for a separate driving performance study. He sustained a concussion 18 months later, and was asked to complete the same driving tasks as previous testing once he was asymptomatic. Poor driving simulator performance and subtle cognitive deficits in complex attention and processing speed were evident despite being symptom-free. Our findings may be useful when considering readiness to drive postconcussion.

Jewish Body Politics

2018 ◽  
Author(s):  
Eliyahu Stern
Keyword(s):  
United States ◽  
Minority Rights ◽  
The United States ◽  
Body Politics ◽  
Eastern European ◽  
The Core ◽  
Two Sides ◽  
Core Features

The idea of a Jewish body provides the background to understand the major Jewish migrations, the core features of modern Jewish politics, the transformation of Judaism as a religion and the role played by Jews in the Minority Rights Movement. Eastern European Jews’ immigration to the United States or Palestine as two sides of the same coin.

scholarly journals Changing our thinking about changing their thinking in older adulthood

2017 ◽  
Vol 29 (9) ◽  
pp. 1405-1407
Author(s):  
Viviana M. Wuthrich
Keyword(s):  
Older Adults ◽  
Individual Differences ◽  
Cognitive Flexibility ◽  
Cognitive Deficits ◽  
Processing Speed ◽  
Cognitive Abilities ◽  
Anxiety And Depression ◽  
Cognitive Changes ◽  
Older Adulthood ◽  
New Learning

It is well-established that as people age, deterioration in cognitive abilities including processing speed, memory, and cognitive flexibility occurs, although vast individual differences occur in the rate and consequences of this decline (Christensen, 2001). Anxiety and depression in late life are also associated with specific cognitive deficits in memory and executive functioning that may impact on new learning (Yochim et al., 2013). Therefore, it is possible that cognitive changes make it more difficult for older adults to learn how to change their thinking particularly in the context of psychological therapy.

scholarly journals Switching perception of musical meters by listening to different acoustic cues of biphasic sound stimulus.

2020 ◽  
Author(s):  
Sotaro Kondoh ◽  
Kazuo Okanoya ◽  
Ryosuke O Tachibana
Keyword(s):  
Music Perception ◽  
Sound Stimulus ◽  
Acoustic Cues ◽  
Point Scale ◽  
Top Down ◽  
Bottom Up ◽  
The Core ◽  
Entire Structure ◽  
Core Features

Meter is one of the core features of music perception. It is the cognitive grouping of regular sound sequences, typically for every 2, 3, or 4 beats. Previous studies have suggested that one can not only passively perceive the meter from acoustic cues such as loudness, pitch, and duration of sound elements, but also actively perceive it by paying attention to isochronous sound events without any acoustic cues. Studying the interaction of top-down and bottom-up processing in meter perception leads to understanding the cognitive system’s ability to perceive the entire structure of music. The present study aimed to demonstrate that meter perception requires the top-down process (which maintains and switches attention between cues) as well as the bottom-up process for discriminating acoustic cues. We created a “biphasic” sound stimulus, which consists of successive tone sequences designed to provide cues for both the triple and quadruple meters in different sound attributes, frequency, and duration, and measured how participants perceived meters from the stimulus in a five-point scale (ranged from “strongly triple” to “strongly quadruple”). Participants were asked to focus on differences in frequency and duration. We found that well-trained participants perceived different meters by switching their attention to specific cues, while untrained participants did not. This result provides evidence for the idea that meter perception involves the interaction between top-down and bottom-up processes, which training can facilitate.

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