scholarly journals Comparative estimation of serum levels of vitamin A, vitamin B12, vitamin D and vitamin E in patients with recurrent aphthous stomatitis and normal individuals – A case-control study

2021 ◽  
Vol 33 (4) ◽  
pp. 442
Author(s):  
AnindyaP Saha ◽  
Subhasish Mustafi ◽  
Rupam Sinha ◽  
Soumyabrata Sarkar ◽  
Debanti Giri ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin E ◽  
Vitamin A ◽  
Vitamin B12 ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Recurrent Aphthous Stomatitis ◽  
Normal Individuals ◽  
Control Study

scholarly journals COMPARISON OF SERUM LEVELS OF VITAMIN A, VITAMIN D AND ZINC IN ACUTE LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN

2020 ◽  
pp. 1-4
Author(s):  
Anil Sharma ◽  
Shalini Dash
Keyword(s):  
Vitamin D ◽  
Vitamin A ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Case Control ◽  
Indian Children ◽  
Serum Vitamin D ◽  
Tract Infections ◽  
Control Study

Aim: Acute lower respiratory infections (ALRIs) are global problem, and there are large differences in mortality rates between developed and developing countries. Deficiency of micronutrients may increase the risk of ALRI. A case-control study was conducted to assess the associations between vitamin A, vitamin D, zinc and ALRI in eastern part of Indian children. Methods: Children aged 1 – 60 months hospitalizes with ALRI (cases, N = 51) were matched to controls on age, sex and socio-economic status (N = 31). The mean Serum levels of Vitamin A, Vitamin D (25-hydroxy vitamin D) and Zinc in cases and controls was compared using student's paired t-test and compared the severity of pneumonia with these levels. Results: Mean (SD) level of serum vitamin A, vitamin D and zinc in the cases were 17.08 (±10.53) ìg/dl; 13.91 (±2.99) ng/ml and 61.51 (±13.84) ìg/dl, respectively. The serum vitamin A, vitamin D and zinc levels were significantly lower in cases of ALRI as compared to controls (p<0.001). In our study serum vitamin D level was significantly associated with severity of ALRIs (p=0.042), and mean level of serum vitamin A was significantly low in case of severe pneumonia as compared to pneumonia (p=0.011). Conclusion: Vitamin A, vitamin D and zinc status was associated with childhood ALRI in matched case-control study in eastern part of India. Randomized trials may establish whether interventions to improve theses micronutrients status can reduce the burden of ALRI in children.

Dietary and serum vitamin D and preeclampsia risk in Chinese pregnant women: a matched case–control study

2021 ◽  
pp. 1-26
Author(s):  
Xue-min Huang ◽  
Yan-hua Liu ◽  
Han Zhang ◽  
Yuan Cao ◽  
Wei-feng Dou ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dietary Intake ◽  
Pregnant Women ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Concentrations ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

Abstract The effect of vitamin D (VD) on the risk of preeclampsia (PE) is uncertain. Few of previous studies focused on the relationship between dietary VD intake and PE risk. Therefore, we conducted this 1:1 matched case-control study to explore the association of dietary VD intake and serum VD concentrations with PE risk in Chinese pregnant women. A total of 440 pairs of participants were recruited during March 2016 to June 2019. Dietary information was obtained using a 78-item semi-quantitative food frequency questionnaire. Serum concentrations of 25(OH)D2 and 25(OH)D3 were measured by liquid chromatography–tandem mass spectrometry. Multivariate conditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Restricted cubic splines (RCS) were plotted to evaluate the dose-response relationship of dietary VD intake and serum VD concentrations with PE risk. Compared with the lowest quartile, the ORs of the highest quartile were 0.45 (95%CI: 0.29-0.71, Ptrend = 0.001) for VD dietary intake and 0.26 (95%CI: 0.11-0.60, Ptrend = 0.003) for serum levels after adjusting for confounders. In addition, the RCS analysis suggested a reverse J-shaped relationship between dietary VD intake and PE risk (P-nonlinearity = 0.02). A similar association was also found between serum concentrations of total 25(OH)D and PE risk (P-nonlinearity = 0.02). In conclusion, this study provides evidence that higher dietary intake and serum levels of VD are associated with the lower risk of PE in Chinese pregnant women.

scholarly journals Mannose-binding lectin serum levels and (Gly54asp) gene polymorphism in recurrent aphthous stomatitis: A case-control study

2021 ◽  
Vol 35 ◽  
pp. 205873842110644
Author(s):  
Shereen A Baioumy ◽  
Shaimaa H Fouad ◽  
Shaimaa A Abdalgeleel ◽  
Ahmed A Baiomy ◽  
Dina E Sallam ◽  
...  
Keyword(s):  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Recurrent Aphthous Stomatitis ◽  
Mannose Binding Lectin ◽  
Aphthous Stomatitis ◽  
Control Group ◽  
Mannose Binding ◽  
Binding Lectin ◽  
Control Study

Objectives: Dysregulation of the immune response appears to play a significant role in recurrent aphthous stomatitis (RAS) development. The main objective of this case–control study is to investigate the blood levels of mannose-binding lectin (MBL) and the frequency of the MBL2 gene (gly54asp) polymorphism in RAS patients, including 40 RAS patients and 40 healthy controls. Methods: Serum MBL levels were determined by ELISA, while the PCR-restriction fragment length polymorphism was used in MBL2 genotyping. Results: The median serum MBL level was significantly lower in the RAS group than in the control group (975 ng/mL (545–1320) vs. 1760 ng/mL (1254–2134); p≤ 0.001). The MBL levels were significantly lower in the BB genotype, whereas they were significantly higher in the wild type AA with a median of 525 and 1340 ng/mL, respectively ( p =0.005). The B allele was expressed in significantly higher percentages of RAS patients than in controls. There was no significant association between MBL serum levels ( p=0.685) or MBL2 codon 54 genotypes ( p=0.382) with the type of ulcers. Conclusion: There was an association between low MBL serum levels and the variant allele B of the MBL2 (gly54asp) gene, and the susceptibility to RAS. As a result, potential novel therapeutic options for RAS patients with MBL deficiency should be investigated.

Vitamin A, D & Zinc Serum Levels in Children with Acute Gastroentritis: A Case Control Study: Tehran, Iran

2016 ◽  
Vol 12 (1) ◽  
pp. 23-27 ◽  
Author(s):  
Samileh Noorbakhsh ◽  
Anahita Izadi ◽  
Ali Akbar Rahbarimanesh ◽  
Shima Javadnia ◽  
Fahimeh Soheilipour
Keyword(s):  
Vitamin A ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Control Study

Association of Cigarette Smoking and Serum Concentrations of Vitamins A and E in Men: A Case-Control Study

2021 ◽  
Author(s):  
Marjan Sohrabi ◽  
Mahmoud Djalali ◽  
Mohammad Hassan Javanbakht ◽  
Niloofar Shekoohi ◽  
Abed Ghavami ◽  
...  
Keyword(s):  
Vitamin E ◽  
Cigarette Smoking ◽  
Vitamin A ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Serum Concentrations ◽  
Blood Concentrations ◽  
Cholesterol Ratio ◽  
Control Study

Background: Cigarette smoking is associated with changes in blood concentrations of some antioxidant vitamins. This study aimed to determine the association of cigarette smoking with serum concentrations of vitamins A and E in men. Methods: This was a case-control study, in which the participants were 80 male smokers and 84 male nonsmokers (age range: 20-60 years). Data on dietary intake, health status, smoking habits, anthropometric characteristics, and vitamin levels were compared between cases and controls. Results: Smokers had significantly lower concentrations of serum vitamin E (p = 0.001) and vitamin A (p = 0.013) compared with nonsmokers. However, serum vitamin E to cholesterol ratio was not significantly different between smokers and nonsmokers. Moreover, the highest circulating concentrations of vitamin E was observed in smokers who smoked ≤9 cigarettes per day (p < 0.03), while and the lowest vitamin E was seen in men smoking ≥20 cigarettes per day. Conclusion: The results of this study identified that cigarette smoking is associated with lower levels of serum vitamin E and vitamin A, although it was not associated with vitamin E to cholesterol ratio.

scholarly journals The Relationship between Dietary Patterns and Depression is mediated by Serum Level of Folate and Vitamin B12: A Case-Control Study

2019 ◽  
Author(s):  
Maryam Khosravi ◽  
Gity Sotoudeh ◽  
Maryam Amini ◽  
Firoozeh Raisi ◽  
Anahita Mansoori ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Folate ◽  
Folate And Vitamin B12 ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Introduction Major depressive disorder is among main worldwide causes of disability. The low medication compliance rates in depressed patients as well as the high recurrence rate of the disease can bring up the nutrition-related factors as a potential preventive or treatment agent for depression. The aim of this study was to investigate the association between dietary patterns and depression via the intermediary role of the serum folate and vitamin B12, total homocysteine, tryptophan, and tryptophan/competing amino acids ratio. Methods This was an individually matched case-control study in which 110 patients with depression and 220 healthy individuals, who completed a semi-quantitative food frequency questionnaire were recruited. In addition, to measure the serum biomarkers 43 patients with depression and 43 healthy people were randomly selected from the study population. To diagnose depression the criteria of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were utilized. Results The findings suggest that the healthy dietary pattern was significantly associated with a reduced odds of depression (OR: 0.75; 95% CI: 0.61-0.93) whereas the unhealthy dietary pattern increased it (OR: 1.382, CI: 1.116–1.71). The mediation analysis showed that the healthy dietary pattern was associated with a reduced risk of depression via increased serum levels of the folate and vitamin B12; however, the unhealthy dietary pattern was associated with increased risk of depression via decreased serum levels of folate and vitamin B12, based on tree adjusted logistic regression models. Conclusion Dietary patterns may be associated with depression by changing the serum levels of folate and vitamin B12. Further studies are required to confirm the mechanism.

scholarly journals The Relationship between Dietary Patterns and Depression is mediated by Serum Level of Folate and Vitamin B12: A Case-Control Study

2019 ◽  
Author(s):  
Maryam Khosravi ◽  
Gity Sotoudeh ◽  
Maryam Amini ◽  
Firoozeh Raisi ◽  
Anahita Mansoori ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Folate ◽  
Folate And Vitamin B12 ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Introduction Major depressive disorder is among main worldwide causes of disability. The low medication compliance rates in depressed patients as well as the high recurrence rate of the disease can bring up the nutrition-related factors as a potential preventive or treatment agent for depression. The aim of this study was to investigate the association between dietary patterns and depression via the intermediary role of the serum folate and vitamin B12, total homocysteine, tryptophan, and tryptophan/competing amino acids ratio. Methods This was an individually matched case-control study in which 110 patients with depression and 220 healthy individuals, who completed a semi-quantitative food frequency questionnaire were recruited. In addition, to measure the serum biomarkers 43 patients with depression and 43 healthy people were randomly selected from the study population. To diagnose depression the criteria of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were utilized. Results The findings suggest that the healthy dietary pattern was significantly associated with a reduced odds of depression (OR: 0.75; 95% CI: 0.61-0.93) whereas the unhealthy dietary pattern increased it (OR: 1.382, CI: 1.116–1.71). The mediation analysis showed that the healthy dietary pattern was associated with a reduced risk of depression via increased serum levels of the folate and vitamin B12; however, the unhealthy dietary pattern was associated with increased risk of depression via decreased serum levels of folate and vitamin B12, based on tree adjusted logistic regression models. Conclusion Dietary patterns may be associated with depression by changing the serum levels of folate and vitamin B12. Further studies are required to confirm the mechanism.

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