scholarly journals Comparison of serum interleukin-37 level in obese, nonobese type ii diabetic patients and healthy controls

2021 ◽  
Vol 20 (2) ◽  
pp. 76
Author(s):  
FadwaE Alhayali ◽  
AysegülA Yücel ◽  
ZainabF Ashoor
Keyword(s):  
Diabetic Patients ◽  
Healthy Controls ◽  
Type Ii

scholarly journals Estimation of Micronutrients (Magnesium and Iron) in Periodontitis Patients with and without Type-2 Diabetes Mellitus

2021 ◽  
Vol 10 (22) ◽  
pp. 1645-1649
Author(s):  
Pallavi Samatha Yalamanchili ◽  
Nirupa Elisetti ◽  
Janaki Kesipeddy ◽  
Bilwa Bindu A ◽  
Bhagyasree Vegunta
Keyword(s):  
Diabetes Mellitus ◽  
Statistical Significance ◽  
Serum Magnesium ◽  
Serum Levels ◽  
Diabetic Patients ◽  
Healthy Controls ◽  
Type Ii ◽  
Group I ◽  
Group 3 ◽  
Group 2

BACKGROUND The focus of this study was to assess the relationship of nutrients (magnesium, iron) in periodontitis and diabetic patients. Serum magnesium (Mg) and iron (Fe) levels were evaluated in periodontitis patients and were compared between diabetic patients with periodontitis and healthy controls. METHODS Total sixty subjects (18 females and 42 males) were recruited in this cross-sectional study and were divided into three groups - Group I (healthy subjects), Group II (chronic generalized periodontitis), Group III (Type II diabetes mellitus and chronic generalized periodontitis). Loe and Silness gingival index and probing pocket depth were used for categorizing chronic generalized periodontitis patients. Serum levels of magnesium and iron were estimated and then compared among the groups. Statistical analysis was done using one-way analysis of variance (ANOVA) and Newmann-Keuls multiple post-hoc procedures. Statistical significance was accepted for P ≤ 0.05. RESULTS Mean serum levels of magnesium (Mg) were 0.89 in Group 3 (Type II DM + CGP), 1.01 in Group 2 (CGP) against 1.52 in Group 1 (Control), which were statistically significant. Mean Iron (Fe) levels showed 165.56 in Group 3 (Type II DM + CGP), 137.77 in Group 2 (CGP) against 78.17 (Control) which is also statistically significant. CONCLUSIONS In this study, we found statistically significant decrease in magnesium and increase in serum iron levels in Group 3 (Type II DM + CGP) compared to Group 2 (CGP) and healthy controls. These findings suggest that trace elements also play an important role in the progression of periodontal disease. KEY WORDS Chronic Periodontitis, Diabetes Mellitus, Iron, Magnesium

scholarly journals Recent trends in the antimicrobial susceptibility patterns of urinary pathogens in type II diabetes mellitus

2018 ◽  
Vol 6 (4) ◽  
pp. 1288
Author(s):  
Dinesh Gurjar ◽  
Akash Mathur ◽  
Ramkrishna Sai ◽  
Arvind Lakesar ◽  
Puneet Saxena
Keyword(s):  
Diabetes Mellitus ◽  
Antimicrobial Susceptibility ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Diabetic Patients ◽  
Healthy Controls ◽  
Type Ii ◽  
E Coli ◽  
Recent Trends ◽  
Susceptibility Patterns

Background: Diabetes mellitus is one of the most frequently encountered diseases in clinical practice and since the diabetic patients are at an increased risk of infections specially those of the urinary tract it is imperative for a physician to be aware of the prevalence and antibiotic susceptibility patterns of urinary pathogens. Thus, in this study we assess the recent trends in antimicrobial susceptibility patterns of urinary pathogens in type II diabetes mellitus.Methods: Ninety-three eligible type II diabetes mellitus cases without genitourinary symptoms or abnormalities along with 93 non-diabetic healthy controls were recruited. Mid-stream urine was collected after taking informed consent and each sample tested using the dipstick, microscopy and culture techniques. Isolates were identified using standard biochemical tests.Results: Prevalence of asymptomatic bacteriuria (ASB) in our study was found to be 34.4% among cases of type II diabetes mellitus while it was 6.45% among non-diabetic healthy controls. E. coli was the most common urinary pathogen isolated. E. coli susceptibility towards amikacin was 85.71%, towards ceftriaxone and nitrofurantoin was 71.73% and for meropenem and doxycycline 66.67% susceptibility was observed. In the one case where pseudomonas was cultured, it was susceptible to meropenem, gentamycin, cefoperazone-sulbactum and cefuroxime. In an isolated case where Proteus species was grown, it showed susceptibility to meropenem, norfloxacin, levofloxacin and co-trimoxazole. Enterobacter species which was grown, showed susceptibility to meropenem, vancomycin, amikacin, nitrofurantoin, norfloxacin, levofloxacin and co-trimoxazole. Gram positive bacteria mainly showed susceptibility to ceftriaxone, teicoplanin, vancomycin and doxycycline.Conclusions: The prevalence of bacteriuria is significantly higher in diabetics as compared to non-diabetics and with the recent trends suggestive of emerging resistance among urinary pathogens to some of the commonly used anti-microbials it is of utmost importance to carry out regular surveillance of bacterial profile and their anti-microbial susceptibilities to formulate updated guidelines for effectively treating urinary infections in diabetic patients.

scholarly journals The Physiological Significance of A-Waves in Early Diabetic Neuropathy: Assessment of Motor Nerve Fibers by Neurophysiological Techniques

2021 ◽  
Vol 15 ◽  
Author(s):  
Qiong Cai ◽  
Guliqiemu Aimair ◽  
Wen-Xiao Xu ◽  
Pei-Yao Xiao ◽  
Lie-Hua Liu ◽  
...  
Keyword(s):  
Conduction Velocity ◽  
Type Ii Diabetes ◽  
Motor Nerve ◽  
Clinical Information ◽  
Nerve Fibers ◽  
Diabetic Patients ◽  
Healthy Controls ◽  
Type Ii ◽  
Significant Difference ◽  
The Right

Objective: This study aimed to investigate how early A-waves could occur in type II diabetes, and what it implied functionally.Methods: We performed conduction velocity distribution (CVD) test in peroneal nerves of 37 type II diabetic patients with normal nerve conduction study (NCS) and 22 age-matched controls. The electrophysiological data and clinical information were analyzed.Results: A-waves were observed in 45.9% of diabetic patients and only in 1 person in healthy controls, all detected in the tibial nerves. The diabetic patients with A-waves showed faster conduction velocity in all quartiles in the motor peroneal nerves compared to the patients without A-waves, and their CVD histograms were shifted to the right side, consisting of a significantly larger percentage of fast conducting fibers. There was no significant difference in the CVD values of the upper extremity nerves among the patients with and without A-waves and the healthy controls.Conclusion: A-waves could occur in type II diabetes as early as when NCS showed normal, and represented as a sign of neuropathy as well as a sign of rescued motor nerve function.

Elevated plasma concentrations of beta-cell tropin (ACTH22-39) in diet-treated type II diabetic patients

Diabetes ◽  
1992 ◽  
Vol 41 (9) ◽  
pp. 1160-1164 ◽  
Author(s):  
J. C. Levy ◽  
J. L. Morton ◽  
M. Davenport ◽  
A. Beloff-Chain ◽  
R. C. Turner
Keyword(s):  
Beta Cell ◽  
Plasma Concentrations ◽  
Diabetic Patients ◽  
Type Ii ◽  
Elevated Plasma

Renal effects of nicardipine, a calcium entry blocker, in hypertensive type II diabetic patients with nephropathy

Diabetes ◽  
1986 ◽  
Vol 35 (11) ◽  
pp. 1206-1214 ◽  
Author(s):  
T. Baba ◽  
T. Ishizaki ◽  
Y. Ido ◽  
K. Aoyagi ◽  
S. Murabayashi ◽  
...  
Keyword(s):  
Calcium Entry ◽  
Diabetic Patients ◽  
Calcium Entry Blocker ◽  
Type Ii ◽  
Renal Effects ◽  
Entry Blocker

Relationship between uric acid and creatinine in pre-diabetic and diabetic patients: Vidarbha region of Maharashtra

2020 ◽  
Vol 11 (3) ◽  
pp. 3412-3417
Author(s):  
Ranjit S. Ambad ◽  
Rakesh Kumar Jha ◽  
Lata Kanyal Butola ◽  
Nandkishor Bankar ◽  
Brij Raj Singh ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Type Ii Diabetes ◽  
Fasting Blood Glucose ◽  
General Medicine ◽  
Control Group ◽  
Diabetic Patients ◽  
Type Ii ◽  
Develop Type ◽  
Low Levels

Prediabetes is a glucose homeostasis condition characterized by decreased absorption to glucose or reduced fasting glucose. Both of these are reversible stages of intermediate hyperglycaemia providing an increased type II DM risk. Pre-diabetes can therefore be viewed as a significant reversible stage which could lead to type II DM, and early detection of prediabetes may contribute to type II DM prevention. Prediabetes patients are at high risk for potential type II diabetes, and 70 percent of them appear to develop Type II diabetes within 10 years. The present study includes total 200 subjects that include 100 Prediabetic patients, 50 T2DM patients and 50 healthy individual. Blood samples were collected from the subjects were obtained for FBS, PPBS, Uric acid and Creatinine estimation, from OPD and General Medicine Wards. Present study showed low levels of Serum Uric Acid in prediabetic and T2DM patients were decreased as compared to control group, while the level of creatinine in prediabetic and diabetic were elevated as compared to control group, were not statically significant. Serum Uric Acid was high in control group and low in prediabetic and diabetic patients. Serum creatinine was declined in control group and increased in prediabetic and diabetic patients with increasing Fasting blood glucose level.

RISK FACTORS FOR EARLY DEVELOPMENT OF POLYNEUROPATHY AMONG TYPE II DIABETIC PATIENTS.

2017 ◽  
Vol 5 (10) ◽  
pp. 1197-1202
Author(s):  
Mahfouz HM ◽  
◽  
HashemA H ◽  
YasserHamed Mostafa ◽  
◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Development ◽  
Diabetic Patients ◽  
Type Ii
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