scholarly journals Risk factors for postcesarean wound infection in a tertiary hospital in Lagos, Nigeria

2020 ◽  
Vol 61 (5) ◽  
pp. 262
Author(s):  
KabiruAfolarin Rabiu ◽  
FatimatMotunrayo Akinlusi ◽  
AdeniyiAbiodun Adewunmi ◽  
TaiwoGaniyat Alausa ◽  
IdayatAdejumoke Durojaiye
Author(s):  
I. A. Onwuezobe ◽  
P. C. Matthew

Aims: Anaerobic causes of pyogenic wound infection are not usually investigated due to difficulties in cultural techniques, lack of equipment and technical man-power. Therefore, this study aimed to investigate the anaerobic bacteria agents of pyogenic infection and the associated risk factors among patients in a tertiary hospital. Study Design: This was a descriptive cross-sectional study conducted at the University of Uyo Teaching Hospital, Uyo and carried out on 136 wound samples from patients. These samples were collected from all consented patients with pyogenic wound infection that met the inclusion criteria. Place and Duration of Study: The study was conducted at Uyo, the capital city of Akwa Ibom State, Nigeria between April and October, 2018. Methodology: Deep wound swabs or aspirated pus samples were collected and inoculated into fresh 25% Sheep Blood Agar plate and incubated in an anaerobic jar containing anaerobic indicator and Gas-pak at 37oC for 48 – 72 hours Identification of isolates was performed following standard procedures. Data were obtained through a well- structured questionnaire and analyzed using SPSS software. Results: Of the 136 samples collected, 127 yielded microbial growth with a total of 202 isolates which included 50 and 2 pure growths of aerobes and anaerobes respectively and 75 combined growths of aerobes and anaerobes. Overall, more aerobes (125) were isolated when compared to the anaerobes (77). Nevertheless, the predominant anaerobe was B. fragilis 26(33.8%). There was a statistical significant relationship between the age of the patient and infection by gram- positive anaerobes (p = 0.002). Conclusion: Bacteriodes fragilis is mainly involved in anaerobic pyogenic wound infections in Uyo, however, only the age of the patient was found to be a factor in the prevalence of infection by gram-positive anaerobes.


Author(s):  
Moon-Sook Kim ◽  
Hyun-Myung Jung ◽  
Hyo-Yeon Lee ◽  
Jinhyun Kim

The purpose of this study was to identify the risk factors of serious fall-related injuries by analyzing the differences between two fall groups: one with serious fall-related injuries and one without such injuries. Applying a retrospective, descriptive investigation study design, we analyzed the degree of fall-related injury and the risk factors related to serious falls by conducting a complete survey of the medical records of fall patients reported throughout one full year, 2017, at a tertiary hospital in Seoul, Korea. Among the patients with reported falls, 188 sustained no injury (63.1%), 72 sustained minor injury (24.2%), and 38 patients sustained serious injury (12.8%). The serious fall-related injuries included eight lacerations requiring suture (2.7%), 23 fractures (7.7%), five brain injuries (1.7%), and two deaths (0.7%). Analysis results indicated that taking anticoagulants/antiplatelet drugs (p = 0.016) and having a fall history (p = 0.038) were statistically significant in the differences between the group with serious injury related to falls and the group without serious injury. Logistic regression revealed that taking anticoagulant/antiplatelet drugs was the factor most significantly correlated with serious injuries related to falls (OR = 2.299, p = 0.022). Results show that it is necessary to develop a patient-tailored fall prevention activity program.


2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
S Singh ◽  
S Gupta ◽  
T S Mishra ◽  
B D Banerjee ◽  
T Sharma ◽  
...  

Abstract Introduction Nephrolithiasis is pathological calcification in the excretory passages of the body and is prevalent among 7.6% of Indians. We aimed to study the various risk factors associated with renal stones from India. Method It was a hospital-based case-control study conducted over 18 months in a tertiary hospital in Delhi. Cases were defined as patients with renal stones diagnosed on the basis of history and radiological examination. Controls were similar to cases in all respects except for the diagnosis and selected from the hospital. A total of 18 risk factors, including age, gender, heavy metals, stress, metabolic factors, alcohol intake, dietary habits, co-morbidities, etc. were assessed. Logistic regression analysis was performed to calculate the strength of the risk associations. Results In the analysis of 60 cases and controls, we found 6 times, 5.5 times, and 2.4 times increased odds of renal stones in patients with increased arsenic, cadmium, and lead concentrations in blood, respectively. Similarly, there are 3 times increased odds of renal stones in patients suffering from stress. Conclusions Exposure to smoke, occupation dust, and contaminated water may lead to an increased ingestion/inhalation of heavy metals like cadmium, arsenic, and predisposing people to an increased risk of renal stones.


Author(s):  
Marcus Rickert ◽  
Michael Rauschmann ◽  
Nizar Latif-Richter ◽  
Mohammad Arabmotlagh ◽  
Tamin Rahim ◽  
...  

Abstract Background and Study Aims The treatment of infections following a spine surgery continues to be a challenge. Negative pressure wound therapy (NPWT) has been an effective method in the context of infection therapy, and its use has gained popularity in recent decades. This study aims to analyze the impact of known risk factors for postoperative wound infection on the efficiency and length of NPWT therapy until healing. Patients and Methods We analyzed 50 cases of NPWT treatment for deep wound infection after posterior and posteroanterior spinal fusion from March 2010 to July 2014 retrospectively. We included 32 women and 18 men with a mean age of 69 years (range, 36–87 years). Individual risk factors for postoperative infection, such as age, gender, obesity, diabetes, immunosuppression, duration of surgery, intraoperative blood loss, and previous surgeries, as well as type and onset (early vs. late) of the infection were analyzed. We assessed the associations between these risk factors and the number of revisions until wound healing. Results In 42 patients (84%), bacterial pathogens were successfully detected by means of intraoperative swabs and tissue samples during first revision. A total of 19 different pathogens could be identified with a preponderance of Staphylococcus epidermidis (21.4%) and S. aureus (19.0%). Methicillin-resistant S. aureus (MRSA) was recorded in two patients (2.6%). An average of four NPWT revisions was required until the infection was cured. Patients with infections caused by mixed pathogens required a significantly higher number of revisions (5.3 vs. 3.3; p < 0.01) until definitive wound healing. For the risk factors, no significant differences in the number of revisions could be demonstrated when compared with the patients without the respective risk factor. Conclusion NPWT was an effective therapy for the treatment of wound infections after spinal fusion. All patients in the study had their infections successfully cured, and all spinal implants could be retained. The number of revisions was similar to those reported in the published literature. The present study provides insights regarding the effectiveness of NPWT for the treatment of deep wound infection after spinal fusion. Further investigations on the impact of potential risk factors for postoperative wound healing disorders are required. Better knowledge on the impact of specific risk factors will contribute to a higher effectiveness of prophylaxis for postoperative wound infections considering the patient-specific situation.


Oncology ◽  
2014 ◽  
Vol 86 (3) ◽  
pp. 127-134 ◽  
Author(s):  
Jae-Woo Jung ◽  
Hye-Ryun Kang ◽  
Se-Hoon Lee ◽  
Sang-Heon Cho

2007 ◽  
Vol 117 (1) ◽  
pp. 166-171 ◽  
Author(s):  
Shih-An Liu ◽  
Yong-Kie Wong ◽  
Chiu-Kwan Poon ◽  
Chen-Chi Wang ◽  
Ching-Ping Wang ◽  
...  

2021 ◽  
pp. 1-6

OBJECTIVE The aim of this study was to investigate the clinical and radiological factors associated with the rupture of a vertebral artery dissecting aneurysm (VADA) and to evaluate whether the stagnation sign is a significant risk factor for rupture of VADA. METHODS Clinical and radiological variables of 117 VADAs treated in a tertiary hospital from September 2008 to December 2020 were retrospectively reviewed. The stagnation sign is defined as the finding of contrast agent remaining in the lesion until the venous phase of angiography. Univariate and multivariate analyses were executed to reveal the associations between rupture status and VADA characteristics. RESULTS The rate of ruptured VADAs was 29.1% (34 of 117) and the stagnation sign was observed in 39.3% (46 of 117). Fusiform shape (OR 5.105, 95% CI 1.591–16.383, p = 0.006), irregular surface (OR 4.200, 95% CI 1.412–12.495, p = 0.010), posterior inferior cerebellar artery (PICA) involvement (OR 3.788, 95% CI 1.288–11.136, p = 0.016), and the stagnation sign (OR = 3.317, 95% CI 1.131–9.732, p = 0.029) were significantly related to rupture of VADA in multivariate logistic regression analysis. CONCLUSIONS This study showed that fusiform shape, irregular surface, PICA involvement, and the stagnation sign may be independent risk factors for the rupture of VADA. Therefore, when the potential risk factors are observed in unruptured VADA, more aggressive treatment rather than follow-up or medical therapy may be considered.


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