Risk Factors of Coronary Artery Disease among Male Teachers in Saudi Arabia, Almadinah City

2018 ◽  
Vol 07 (05) ◽  
Author(s):  
Faisal O Alatawi
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Saudi Arabia ◽  
Coronary Artery ◽  
Male Teachers ◽  
Artery Disease

scholarly journals Population awareness of coronary artery disease risk factors in Jeddah, Saudi Arabia: a cross-sectional study

2019 ◽  
Vol Volume 12 ◽  
pp. 63-70 ◽  
Author(s):  
Mohammed Ali Almalki ◽  
Maram Nader AlJishi ◽  
Maie Abdulrhman Khayat ◽  
Hotoun Fayez Bokhari ◽  
Ahmed Hussein Subki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Saudi Arabia ◽  
Coronary Artery ◽  
Disease Risk ◽  
Cross Sectional Study ◽  
Coronary Artery Disease Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
Artery Disease

scholarly journals Risk factors of coronary artery disease in different regions of Saudi Arabia

2000 ◽  
Vol 6 (2-3) ◽  
pp. 465-474
Author(s):  
A. K. Osman ◽  
M. M. Al Nozha
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Saudi Arabia ◽  
Coronary Artery ◽  
Disease Risk ◽  
Coronary Artery Disease Risk ◽  
Obesity Prevalence ◽  
Nutrition Survey ◽  
The People ◽  
Artery Disease

A national nutrition survey was carried out in Saudi Arabia between 1989 and 1994. One objective was to investigate the prevalence of well established atherogenic risk factors among adults 18 years and older, namely obesity, hypercholesterolaemia, hypertriglyceridaemia, diabetes mellitus and high systolic and diastolic blood pressure. Obesity prevalence was positively correlated with all five coronary artery disease risk factors investigated. Variation among regions in relation to the prevalence of these risk factors was observed. Saudi Arabia’s ecology has resulted in variation in the lifestyle and food consumption patterns of the people of the different regions, which might be a major underlying cause of the variation and high prevalence of coronary artery disease risk factors

scholarly journals Prevalence of coronary artery disease and its associated risk factors in Aljouf region of Saudi Arabia

2022 ◽  
Vol 21 (1) ◽  
pp. 201-205
Author(s):  
Md Sayed Ali Sheikh
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Saudi Arabia ◽  
Coronary Artery ◽  
Medical Science ◽  
Laboratory Data ◽  
Individual Risk ◽  
Total Prevalence ◽  
Artery Disease ◽  
Associated Risk Factors

Objective:Toevaluate the prevalence of coronary artery disease (CAD) with its associated risk factors among Saudi population in Aljouf, Sakaka, Saudi Arabia. Methods: This is a retrospective hospital based study conducted at King Abdul Aziz specialized hospital Sakaka Aljouf, Saudi Arabia by selecting participants with diagnosed CAD by coronary angiogram, the meanage 55.1 ± 10.8 yrs ( range 35-75-years)over a period ofJanuary 2019to December 2019. Demographic characteristics included age, sex,diabetes, hypertension, smoking and family history of CAD. Laboratory data included such as total cholesterol, triglyceride, LDL and HDL levels. Collected data were analyzed by using SPSS 20.00software. Results: One hundred two participants, out of eight hundred fifty five were diagnosed CADwhich included 64.7% stable angina and 35.2% unstable angina. The total prevalence of CAD obtained from this study was11.9% among male and female was7.89% and 4.621% respectively (P<0.0001). Diabetes (85.7%) and dyslipidemia 94.2%weremost important risk factors in female compared to male 59.1% and 62.2% respectively, while hypertension 82% higher in male than female 51.4 % considers as a significant (p<0.001). Smoking considered as an individual risk factor of 94% for male coronary artery disease patients. Conclusion:The prevalence of CAD was higher in male 7.89 % than female 4.21% and its associated risk factors including hypertension and cigarette smoking. Bangladesh Journal of Medical Science Vol. 21(1) 2022 Page : 201-205

Elevated level of circulatory sTLT1 induces inflammation through SYK/MEK/ERK signalling in coronary artery disease

2019 ◽  
Vol 133 (22) ◽  
pp. 2283-2299
Author(s):  
Apabrita Ayan Das ◽  
Devasmita Chakravarty ◽  
Debmalya Bhunia ◽  
Surajit Ghosh ◽  
Prakash C. Mandal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Chronic Inflammation ◽  
Ex Vivo ◽  
Human Subjects ◽  
Critical Role ◽  
Atherosclerotic Cardiovascular Disease ◽  
Tnf Α ◽  
Artery Disease

Abstract The role of inflammation in all phases of atherosclerotic process is well established and soluble TREM-like transcript 1 (sTLT1) is reported to be associated with chronic inflammation. Yet, no information is available about the involvement of sTLT1 in atherosclerotic cardiovascular disease. Present study was undertaken to determine the pathophysiological significance of sTLT1 in atherosclerosis by employing an observational study on human subjects (n=117) followed by experiments in human macrophages and atherosclerotic apolipoprotein E (apoE)−/− mice. Plasma level of sTLT1 was found to be significantly (P<0.05) higher in clinical (2342 ± 184 pg/ml) and subclinical cases (1773 ± 118 pg/ml) than healthy controls (461 ± 57 pg/ml). Moreover, statistical analyses further indicated that sTLT1 was not only associated with common risk factors for Coronary Artery Disease (CAD) in both clinical and subclinical groups but also strongly correlated with disease severity. Ex vivo studies on macrophages showed that sTLT1 interacts with Fcɣ receptor I (FcɣRI) to activate spleen tyrosine kinase (SYK)-mediated downstream MAP kinase signalling cascade to activate nuclear factor-κ B (NF-kB). Activation of NF-kB induces secretion of tumour necrosis factor-α (TNF-α) from macrophage cells that plays pivotal role in governing the persistence of chronic inflammation. Atherosclerotic apoE−/− mice also showed high levels of sTLT1 and TNF-α in nearly occluded aortic stage indicating the contribution of sTLT1 in inflammation. Our results clearly demonstrate that sTLT1 is clinically related to the risk factors of CAD. We also showed that binding of sTLT1 with macrophage membrane receptor, FcɣR1 initiates inflammatory signals in macrophages suggesting its critical role in thrombus development and atherosclerosis.

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