scholarly journals PDK2 and ABCG2 genes polymorphisms are correlated with blood glucose levels and uric acid in Tibetan gout patients

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
Y.C. Ren ◽  
T.B. Jin ◽  
X.D. Sun ◽  
T.T. Geng ◽  
M.X. Zhang ◽  
...  
Author(s):  
Rusli Badaruddin ◽  
Rahim Aka ◽  
Abdul Rahman Ollong ◽  
Ning Ayu Dwi Tiya

ABSTRACT          This study aims to assess cholesterol, uric acid and blood glucose levels in laying hens which are fed with the addition of betel leaf juice (Piper Bettle Linn). There were 16 chickens used in layer phase hens. The cage used is an individual cage equipped with a place for feeding and drinking water. The treatments in this study consisted of: (P0) commercial feed + 0 ml of betel leaf juice, (P1) commercial feed + 5 ml of betel leaf juice, (P2) commercial feed + 10 ml of betel leaf juice, and (P3) commercial feed + 15 ml of betel leaf juice. The variables observed were cholesterol, uric acid and blood glucose levels. The data obtained from the research results were analyzed using variance and continued with Duncan's multiple range test. The results showed that the administration of betel leaf juice had no significant effect (p <0.05) on cholesterol, uric acid and blood glucose levels in layer phase hens. Based on the results of the study, it can be concluded that the administration of betel leaf juice does not affect the amount of cholesterol, uric acid, and glucose levels in layer phase hens, but these conditions are still in normal physiological conditions. Keywords: uric acid, layer hens, glucose, cholesterol ABSTRAK Penelitian ini bertujuan untuk mengkaji tentang kadar kolesterol, asam urat dan glukosa darah ayam petelur yang diberi penambahan jus daun sirih (Piper betle Linn) pada level yang berbeda. Ayam yang digunakan sebanyak 16 ekor induk ayam petelur betina fase layer. Kandang yang digunakan yaitu kandang individu yang dilengkapi dengan tempat pakan dan air minum. Perlakuan pada penelitian ini terdiri atas: (P0) pakan basal + 0 ml jus daun sirih,  (P1) pakan basal + 5 ml jus daun sirih,  (P2) pakan basal + 10 ml jus daun sirih, dan (P3) pakan basal + 15 ml jus daun sirih. Variabel yang diamati adalah kadar kolesterol, asam urat, dan glukosa darah. Data yang diperoleh dari hasil penelitian dianalisis menggunakan sidik ragam dan dilanjutkan dengan uji jarak berganda Duncan. Hasil penelitian menunjukkan bahwa pemberian jus daun sirih tidak memberikan pengaruh yang nyata (p<0.05) terhdadap kadar kolesterol, asam urat dan glukosa darah ayam petelur fase layer. Berdasarkan hasil penelitian dapat disimpulkan bahwa pemberian jus daun sirih tidak mempengaruhi jumlah kadar kolestero, asam urat, dan glukosa ayam petelur fase layer, namun kondisi tersebut masih dalam kondisi fisiologis normal. Kata Kunci : asam urat, ayam petelur, glukosa, kolesterol  


2010 ◽  
Vol 10 (1) ◽  
pp. 54-59 ◽  
Author(s):  
Adlija Čaušević ◽  
Sabina Semiz ◽  
Amra Macić-Džanković ◽  
Bakira Cico ◽  
Tanja Dujić ◽  
...  

Recent studies have introduced serum uric acid (UA) as a potential risk factor for developing diabetes, hypertension, stroke, and cardiovascular diseases. The value of elevated levels of UA in serum as a risk factor for diabetes development is still under scrutiny. Recent data suggest that clearance of UA is being reduced with increase in insulin resistance and UA as a marker of prediabetes period. However, conflicting data related to UA in serum of patients with Type 2 diabetes prompted us to study the urine/serum ratio of UA levels (USRUA) in these patients and healthy controls. All subjects included in the study were free of evidence of hepatitis B or C viral infection or active liver and kidney damage. Patients receiving drugs known to influence UA levels were also excluded from this study. Analysis of glucose and uric acid were performed on Dade Behring analyzer using standard IFCC protocols. Interestingly, our data demonstrated about 2.5 fold higher USRUA values in diabetic patients as compared to control subjects. Furthermore, there was a trend of correlation of USRUA value with the blood glucose levels in diabetic patients, which was more prominent in diabetic men than in women. With aging, levels of uric acid increased in serum of diabetic patients, and this effect was also more profound in male than in female diabetics. In conclusion, this study showed significantly elevated USRUA levels in patients with Type 2 diabetes, a negative USRUA correlation with the blood glucose levels in diabetic patients, and an effect of sex and age on the uric acid levels. Since literature data suggest a strong genetic effect on UA levels, it would be pertinent to perform further, possibly genetic studies, in order to clarify gender and ethnic differences in UA concentrations.


2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Ida Arjani

Background Uric acid is an adjunct product of normal metabolism of the digestion of protein foods containing purines or from the decomposition of purines (damaged body cells), which should be excreted through the kidneys, feces or sweat. While blood glucose levels should be maintained in sufficient concentration to provide nutrients for the organs of the body. Conversely, too high glucose concentrations can also have negative effects such as osmotic diuresis and cell dehydration.The purpose of this study was to determine the description of uric acid levels, blood glucose and level of knowledge of the elderly in Samsam Village, Kerambitan District, Tabanan Regency.Method, The type of research used is descriptive. The population in this study were all elderly in Samsam village area with sample size of 57 samples. Sampling technique used Nonprobability Sampling and sampling with Accidental Sampling.Result.From 57 respondents, there were 14 men (25%), women 43 people (75%), age group ≤ 60 years were 18 persons (32%) and age group 60 years were 39 people (68% ). The results of examination of uric acid levels of respondents in the normal category of 7 people (12%) and high 50 people (88%). Blood Glucose Levels when the respondents were normal 52 people (91%) and high 5 people (9%). Knowledge of respondents was 22 people (39%) in good category and 35 people (61%) in medium category.Conclusion, as many as 88% of respondents have high uric acid levels, 9% of respondents have high blood glucose levels and 61% of respondents have knowledge in the category of being Keywords: Uric Acid Level, Blood Glucose, Elderly’s knowledge


2016 ◽  
Vol 3 (2) ◽  
pp. 114
Author(s):  
Rinda Binugraheni ◽  
Susan Primadevi ◽  
Rahmat Budi Nugroho ◽  
Dian Kresnadipayana ◽  
Gregorius Indra Budianto

Nusukan is one village with a tendency for people who prefer to consume fast food and lack of attention to a healthy lifestyle. This causes a lot of society are affected by diabetes mellitus, hyperlipidemia and uric acid. Nusukan society RW 22 who are not aware that they have the disease. For it is necessary to check blood glucose levels, cholesterol and uric acid that can be detected early. The purpose of this program is to provide education on the dangers and prevention of diabetes mellitus, hyperlipidemia, and uric acid. It is also to help people to detect diabetes mellitus, hyperlipidemia and uric acid using stick test and spektropothometry method. Of the 30 people there were seven people who are abnormal blood glucose levels or diabetes mellitus, according stated test stick method, whereas in spectrophotometric methods there are 2 people. Uric acid test of RW 22, there are 7 people who exceed the normal limits, whereas cholesterol levels there are 22 people who exceed normal cholesterol levels (hyperlipidemia) with a test stick method, whereas in sprektropothometry there are 18 people who hyperlipidemia. Methods stick test results show higher levels compared to the spectrophotometric method.


2006 ◽  
Vol 31 (03) ◽  
Author(s):  
H Hager ◽  
E Giorni ◽  
A Felli ◽  
B Mora ◽  
M Hiesmayr ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2167-PUB
Author(s):  
KOHEI SURUGA ◽  
TSUYOSHI TOMITA ◽  
MASAKAZU KOBAYASHI ◽  
TADAHIKO MITSUI ◽  
KAZUNARI KADOKURA

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 776-P
Author(s):  
RACHEL BRANDT ◽  
MINSUN PARK ◽  
LAURIE T. QUINN ◽  
MINSEUNG CHU ◽  
YOUNGKWAN SONG ◽  
...  

Author(s):  
Hariyadi DM ◽  
Athiyah U ◽  
Hendradi E ◽  
Rosita N ◽  
Erawati T ◽  
...  

The prevention of Diabetic Mellitus (DM) and its complications is the main aim of this study, in addition to the training of lotion foot care application and the development of small scale industry. The research team delivered knowledge in the form of training on Diabetic Mellitus, healthy food, treatment and prevention of complications, and small-scale production of cosmetic products. The aim of this study was to determine the correlation between training on diabetic and lotion foot care application as preventive measures against diabetic complications on the patient's blood glucose levels in the community of residents in Banyuurip Jaya, Surabaya. It was expected from this training that the knowledge of the residents increases and people living with diabetic undergo lifestyle changes and therefore blood sugar levels can be controlled. The parameters measured in this research were blood glucose levels, the anti diabetic drug types consumed, and compliance on diabetics. This study used the data taken from 60 patients with DM over a period of one month. Questionnaires and log books was used to retrieve data and changes in blood glucose levels in diabetic patients. The results showed the demographic data of patients with type 2 diabetic of 85% female and 15% male, with the range of patients aged of 61-70 years of 46.67% and had history of diabetic (90%). The history of drugs consumed by respondents was anti diabetic drugs such as metformin (40%), glimepiride (33.37%) and insulin (6.67%). In addition, the increased knowledge of DM patients after being given the training compared to before training was shown in several questions in the questionnaire. A statistical analysis using t-test analyzed a correlation between training provided in order to enhance understanding of the patient, as well as correlation with blood glucose levels. A paired T-test showed that there was a relationship between the knowledge of trainees before and after training (p less than 0.05). An interesting result was that there was no relationship between blood glucose levels before and after training provided (p> 0.05).


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