GAMBARAN KADAR ASAM URAT, GLUKOSA DARAH DAN TINGKAT PENGETAHUAN LANSIA DI DESA SAMSAM KECAMATAN KERAMBITAN KABUPATEN TABANAN

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Ida Arjani

Background Uric acid is an adjunct product of normal metabolism of the digestion of protein foods containing purines or from the decomposition of purines (damaged body cells), which should be excreted through the kidneys, feces or sweat. While blood glucose levels should be maintained in sufficient concentration to provide nutrients for the organs of the body. Conversely, too high glucose concentrations can also have negative effects such as osmotic diuresis and cell dehydration.The purpose of this study was to determine the description of uric acid levels, blood glucose and level of knowledge of the elderly in Samsam Village, Kerambitan District, Tabanan Regency.Method, The type of research used is descriptive. The population in this study were all elderly in Samsam village area with sample size of 57 samples. Sampling technique used Nonprobability Sampling and sampling with Accidental Sampling.Result.From 57 respondents, there were 14 men (25%), women 43 people (75%), age group ≤ 60 years were 18 persons (32%) and age group 60 years were 39 people (68% ). The results of examination of uric acid levels of respondents in the normal category of 7 people (12%) and high 50 people (88%). Blood Glucose Levels when the respondents were normal 52 people (91%) and high 5 people (9%). Knowledge of respondents was 22 people (39%) in good category and 35 people (61%) in medium category.Conclusion, as many as 88% of respondents have high uric acid levels, 9% of respondents have high blood glucose levels and 61% of respondents have knowledge in the category of being Keywords: Uric Acid Level, Blood Glucose, Elderly’s knowledge

2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Dhyana Putri

AbstractBackground Gestational diabetes mellitus (GDM) was a condition of glucose intolerance that occur during pregnancy detected by examining blood glucose levels. Objective This study aims to measure fasting blood glucose levels at the second and third trimesters pregnant women in  Puskesmas I Denpasar Selatan-based on certain characteristics. Methods The type of this study is descriptive and using simple random sampling technique. Samples in this study amounted to 33 women. Blood glucose levels measured by venous blood samples with hexokinase method. Result The study results obtained 28 women (84,85%) in the not risk of GDM category and five women (15,15%) in the risk of GDM category. High blood glucose levels obtained four women (12,12%) in the category 25 years and one women (3,03%) in the category 25, on the characteristics of the gestational age obtain two women (6,06%) in the second trimester and three women (9,09%) in the third trimester, on the characteristics of DM in the family obtained one women (3,03%) with a history of DM.Conclusion  The conclusion of this research obtained fasting blood glucose level in trimester II and III pregnant women at Puskesmas I Denpasar Selatan ranged between 66 - 120 mg/dL. Keywords: blood glucose, pregnant women, gestational diabetes 


2020 ◽  
Vol 17 (2) ◽  
pp. 46
Author(s):  
Pascalis Adhi Kurniawan ◽  
Rinawati Satrio

Diabetes Mellitus is a metabolic disorder characterized by an increase in blood glucose levels (hyperglycemia) due to disturbances in insulin secretion and insulin action. Diabetes mellitus (DM) is a disease characterized by high blood glucose levels, because the body cannot release or use insulin adequately. There are many factors that trigger or aggravate periodontitis, including plaque accumulation, calculus (tartar), and systemic factors such as diabetes mellitus. Objective: To explain that there is a close relationship between elevated blood glucose levels and periodontitis. Case Description: A 77 year old woman presented with a loose left upper tooth and pain during eating. The patient admitted to having a history of systemic disease, namely diabetes mellitus. Intra oral examination was found on 27th grade 3 luxation, 6 mm gingival recession, 4 mm probing depth, debris around the teeth, oral hygiene tends to be poor. The therapy provided is in the form of education on the effect of diabetes mellitus on teeth and the condition of the oral cavity in general, as well as the importance of maintaining health and food consumption so that blood sugar conditions are controlled. Conclusion: Periodontal disease can be affected by DM. Periodontitis is one of the manifestations of DM in the oral cavity. The severity of periodontitis can result from an increase in blood glucose levels.


2021 ◽  
pp. 1-8
Author(s):  
Jae-Hun Lee ◽  
Sang Hee Ji ◽  
Jae Yun Jung ◽  
Min Young Lee ◽  
Chi-Kyou Lee

Introduction: Diabetes mellitus (DM) is a systemic disease characterized by hyperglycemia and several pathological changes. DM-related hearing dysfunctions are associated with histological changes. Here, we explore hearing function and synaptic changes in the inner hair cells (IHCs) of rats with streptozotocin (STZ)-induced diabetes. Methods: STZ was injected to trigger diabetes. Rats with DM were exposed to narrow-band noise (105 dB SPL) for 2 h, and hearing function was analyzed 1, 3, 7, and 14 days later. Both the hearing threshold and the peak 1 amplitude of the tone auditory brainstem response were assessed. After the last functional test, animals were sacrificed for histological evaluation. Results: We found no changes in the baseline hearing threshold; however, the peak 1 amplitude at the low frequency (4 kHz) was significantly higher in both DM groups than in the control groups. The hearing threshold had not fully recovered at 14 days after diabetic rats were exposed to noise. The peak 1 amplitude at the higher frequencies (16 and 32 kHz) was significantly larger in both DM groups than in the control groups. The histological analysis revealed that the long-term DM group had significantly more synapses in the 16 kHz region than the other groups. Conclusions: We found that high blood glucose levels increased peak 1 amplitudes without changing the hearing threshold. Diabetic rats were less resilient in threshold changes and were less vulnerable to peak 1 amplitude and synaptic damage than control animals.


Author(s):  
Mohsen Askarbioki ◽  
Mojtaba Mortazavi ◽  
Abdolhamid Amooee ◽  
Saeid Kargar ◽  
Mohammad Afkhami-Ardekani ◽  
...  

Objective: Today, there are various non-invasive techniques available for the determination of blood glucose levels. In this study, the level of blood glucose was determined by developing a new device using near-infrared (NIR) wavelength, glass optical waveguide, and the phenomenon of evanescent waves. Materials and Methods: The body's interstitial fluid has made possible the development of new technology to measure the blood glucose. As a result of contacting the fingertip with the body of the borehole rod, where electromagnetic waves are reflected inside, evanescent waves penetrate from the borehole into the skin and are absorbed by the interstitial fluid. The electromagnetic wave rate absorption at the end of the borehole rod is investigated using a detection photodetector, and its relationship to the people's actual blood glucose level. Following precise optimization and design of the glucose monitoring device, a statistical population of 100 participants with a maximum blood glucose concentration of 200 mg/dL was chosen. Before measurements, participants put their index finger for 30 seconds on the device. Results: According to this experimental study, the values measured by the innovative device with Clark grid analysis were clinically acceptable in scales A and B. The Adjusted Coefficient of Determination of the data was estimated to be 0.9064. Conclusion: For future investigations, researchers are recommended to work with a larger statistical population and use error reduction trends to improve the accuracy and expand the range of measurements.


2021 ◽  
pp. neurintsurg-2021-017771
Author(s):  
Carlos Perez-Vega ◽  
Ricardo A Domingo ◽  
Shashwat Tripathi ◽  
Andres Ramos-Fresnedo ◽  
Samir Kashyap ◽  
...  

Mechanical thrombectomy (MT) represents the mainstay of treatment for patients with acute ischemic stroke due to large-vessel occlusion (LVO). Intravenous thrombolysis has been associated with worse clinical outcome in patients presenting with high blood glucose levels at admission; to date the true effect of hyperglycemia in the setting of MT has not been fully elucidated. In this meta-analysis, we analyzed the influence of high blood glucose levels at admission on clinical outcome after MT. Ovid EMBASE, PubMed, Scopus, and Cochrane Library databases were searched from their dates of inception up to March 2021. An initial search identified 2118 articles representing 1235 unique studies. After applying selection criteria, three prospective and five retrospective studies were analyzed, yielding a pooled cohort of 5861 patients (2041 who presented with hyperglycemia, and 3820 who presented with normal blood glucose levels). Patients in the hyperglycemia group were less likely to have a modified Ranking Scale (mRS) score <3 (risk ratio (RR): 0.65; 95% CI 0.59 to 0.72; p<0.0001; I2=13%), and had an increased risk of symptomatic intracranial hemorrhage (sICH) (RR: 2.07; 95% CI 1.65 to 2.60; p<0.0001; I2=0%) and mortality (RR: 1.73; 95% CI 1.57 to 1.91; p<0.0001; I2=0%). Patients who present with hyperglycemia and undergo MT for treatment of LVO have an increased risk of unfavorable clinical outcome, sICH, and mortality. Glucose levels at admission appear to be a prognostic factor in this subset of patients. Further studies should focus on evaluating control of the glucose level at admission as a modifiable risk factor in patients undergoing MT for LVO.


2011 ◽  
Vol 3 ◽  
pp. CMT.S6227 ◽  
Author(s):  
Kathryn MS Johnson ◽  
Kathleen Schurr

Type 2 diabetes mellitus (T2DM) has become an epidemic, with worldwide projections indicating that more than 336 million people will be afflicted with the disease by 2030. T2DM is characterized by inappropriately high blood glucose levels due to a deficiency in insulin secretion, action, or both. Despite the horrific complications that occur with chronic elevations of blood glucose levels, less than half of those with T2DM do not maintain proper glycemic control. Sitagliptin (Januvia, Merck and Co., Whitehouse Station, New Jersey) is a novel diabetes therapy approved for use in the U.S. and Europe. This small molecule inhibits the activity of DPP-4, a peptidase that degrades the glucoregulatory hormone GLP-1. Sitagliptin increases glucoregulation in individuals with T2DM both as a monotherapy and in combination with other antihyperglycemic drugs, with a low risk of adverse side effects.


2011 ◽  
Vol 278 (1724) ◽  
pp. 3490-3496 ◽  
Author(s):  
Detlev H. Kelm ◽  
Ralph Simon ◽  
Doreen Kuhlow ◽  
Christian C. Voigt ◽  
Michael Ristow

High blood glucose levels caused by excessive sugar consumption are detrimental to mammalian health and life expectancy. Despite consuming vast quantities of sugar-rich floral nectar, nectar-feeding bats are long-lived, provoking the question of how they regulate blood glucose. We investigated blood glucose levels in nectar-feeding bats ( Glossophaga soricina ) in experiments in which we varied the amount of dietary sugar or flight time. Blood glucose levels increased with the quantity of glucose ingested and exceeded 25 mmol l −1 blood in resting bats, which is among the highest values ever recorded in mammals fed sugar quantities similar to their natural diet. During normal feeding, blood glucose values decreased with increasing flight time, but only fell to expected values when bats spent 75 per cent of their time airborne. Either nectar-feeding bats have evolved mechanisms to avoid negative health effects of hyperglycaemia, or high activity is key to balancing blood glucose levels during foraging. We suggest that the coevolutionary specialization of bats towards a nectar diet was supported by the high activity and elevated metabolic rates of these bats. High activity may have conferred benefits to the bats in terms of behavioural interactions and foraging success, and is simultaneously likely to have increased their efficiency as plant pollinators.


2016 ◽  
Vol 8 (9) ◽  
pp. 159
Author(s):  
Muhammad Bilal ◽  
Abdul Haseeb ◽  
Mohammad Hassaan Khan ◽  
Akash Khetpal ◽  
Muhammad Saad ◽  
...  

<p><strong>INTRODUCTION: </strong>Perioperative hyperglycemia has been shown to be related to higher levels of morbidity and mortality in patients on cardiopulmonary bypass (CPB) undergoing coronary artery bypass grafting (CABG), both diabetic and non-diabetic. Blood electrolytes, like sodium, potassium, calcium, and chloride play a very important role in the normal functioning of the body and can lead to a variety of clinical disorders if they become deficient. A minimal number of studies have been conducted on the simultaneous perioperative changes in both blood glucose and electrolyte levels during CPB in Pakistan. Therefore, our aim is to record and compare the changes in blood glucose and electrolyte levels during CPB in diabetic and non-diabetic patients.</p><p><strong>MATERIALS &amp; METHODS: </strong>This was a prospective, observational study conducted on 200 patients who underwent CABG with CPB, from October 2014 to March 2015. The patients were recruited from the Cardiac Surgery Ward, Civil Hospital Karachi after they complied with the inclusion criteria. Repeated-measures analysis of variance (ANOVA) was used to compare the trend of the changes perioperatively for the two groups.</p><p><strong>RESULTS: </strong>There was no significant difference in changes in blood glucose between the two groups (<em>P</em> = 0.62). The only significant difference detected between the two groups was for PaCO<sub>2</sub> (<em>P</em> = 0.001). Besides, further analysis revealed insignificant group differences for the trend changes in other blood electrolytes (<em>P</em> &gt; 0.05).</p><p><strong>CONCLUSION: </strong>Our findings highlighted that there is no significant difference in blood electrolytes changes and the increase in blood glucose levels between diabetic and non-diabetic patients.</p>


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