scholarly journals Case Report: A Case of Tuberculosis with Psoriasiform Lichen Scrofulosorum Exhibiting Koebner’s Phenomenon followed by Scrofuloderma

Author(s):  
Ishika Muradia ◽  
Geeti Khullar ◽  
Shruti Sharma ◽  
Sachin Kolte

Lichen scrofulosorum is the most common tuberculid in the Indian population and the second most common form of cutaneous tuberculosis. We discuss an uncommon presentation of lichen scrofulosorum, with psoriasiform morphology and koebnerization at tuberculin test site, associated with cervical lymphadenitis in a 17-year-old girl. Although the cutaneous lesions resolved completely after 3 months of antitubercular treatment (ATT), she developed scrofuloderma in the left cervical region at 4 months. In the absence of rifampicin resistance, ATT was continued for another 6 months, with no further evidence of disease activity. This case represents an infrequent occurrence of lichen scrofulosorum followed by scrofuloderma, which necessitated a prolonged course of first-line ATT.

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 509
Author(s):  
Maria Qadri ◽  
Qurban Hussain Sheikh ◽  
Mir Tahir Hussain Talpur ◽  
Uzair Yaqoob ◽  
Khalil Ullah Shabbir

Cutaneous tuberculosis (TB) can present in a number of ways, making it difficult to diagnose. It most commonly presents as scrofuloderma, which commonly affects the supra-clavicular region, axilla and the cervical region. All the different presentations of cutaneous TB should be known to clinicians, in order to diagnose it early. The objective of this article is to describe a case of scrofuloderma presenting with different cutaneous lesions at the same time, which were culture negative. We present a 23-year-old male with no known co-morbidities, presenting to us with fever and multiple swellings on the body. Cultures of pus and blood were negative for TB; GeneXpert detected the microorganism. Cutaneous TB, although a rare disease with wide spectrum of cutaneous lesions, should be considered in differential diagnosis of cold abscesses and nodules, especially of the head and neck region.


2006 ◽  
Vol 10 (2) ◽  
pp. 99-103 ◽  
Author(s):  
Roberta F. J. Criado ◽  
Paulo Ricardo Criado ◽  
Cidia Vasconcellos ◽  
José Carlos M. Szajubok ◽  
Nilceo S. Michalany ◽  
...  

Background: The cardinal signs and symptoms of adult-onset Still's disease (AOSD) include periodic fever, arthralgia and arthritis, lymphadenopathy, hepatosplenomegaly, an evanescent rash accompanied by neutrophilic granulocytosis, and a negative rheumatoid factor and antinuclear antibody test. Objective: To alert clinicians and dermatologists to internal diseases such as AOSD when assisting patients with urticarial eruptions and systemic symptoms. Methods: A case report of a 52-year-old white woman who received conventional therapy for urticaria for 3 years, with no improvement. Following this period, a diagnosis of AOSD was performed based on the presence of systemic symptoms. Results: The inflammatory activity markers decreased by the second month of methotrexate therapy; however, the cutaneous lesions failed to disappear. Thalidomide was initiated, and total improvement of the cutaneous lesions was observed after 2 weeks. Conclusion: Urticarial rash is an uncommon presentation of AOSD, and clinicians must be alert to the possibility of a misdiagnosis in these cases.


2016 ◽  
Vol 85 (2) ◽  
pp. 41-43
Author(s):  
Robert Bobotsis ◽  
Brandon Chau

Skin cancer is currently the most common cancer type afflicting North Americans today and with an aging population the incidence is likely to increase. Certain skin cancers such as melanoma can result in significant morbidity and mortality especially if not identified and treated early. The traditional ABCDE rule (asymmetric shape, irregular borders, variation in colour, diameter >6 mm and evolution/elevation of the lesion) used to identify concerning tumours will in fact miss many early melanomas. This problem is exacerbated in patients with hereditary forms of melanoma such as Familial Atypical Multiple- Mole Melanoma (FAMMM) syndrome where multiple atypical nevi satisfying the ABCDE criteria are present and would therefore warrant biopsy. Most of these biopsies would be unnecessary and would increase the patient’s morbidity. Dermatoscopy is a clinical tool that provides a bridge between clinical and histopathologic evaluation and has proven to be helpful in triaging suspicious lesions in the general population and to be a first-line screening tool to increase the detection of early melanomas in patients with FAMMM.


2020 ◽  
Vol 7 (1) ◽  
pp. 164-168
Author(s):  
Florica Sandru ◽  
Mihai Cristian Dumitrascu ◽  
Aida Petca ◽  
Raluca Gabriela Miulescu ◽  
Tiberiu Tebeica ◽  
...  

Metastatic cutaneous lesions are seen more commonly in breast cancer than in any other malignancy in women. Secondary breast cancer happens when cancer cells spread from the breast to other parts of the body. Sometimes breast cancer cells can spread to the skin. This can happen through the blood or lymphatic system. The presence of skin metastases signifies widespread systemic disease and a poor prognosis. The chest wall, the abdomen, the back, and the upper extremities are common sites.We present the case of a 69-year-old woman presented to our Surgery Department in June 2019, after appearing in the Dermatology Department a week ago, for the appearance of multiple subcutaneous painless, hardened, skin-colored nodules spread to the cervical region, anterior chest walls and upper limbs. Anatomopathological examination of the skin biopsy, performed on the anterior face of the left arm, showed dermal fragment with neoplastic, suggestive for lobular breast carcinoma (stage IV). The patient was referred to the oncological surgery department where our patient underwent a left total mastectomy and sentinel lymph node biopsy. The technique of mastectomy was the Madden technique. The surgery has no healing character, being more a necessity intervention that seeks to avoid the complications of the local evolution of the disease, such as ulceration, hemorrhage or suppuration, the possibility of applying the other forms of treatment (radiotherapy and / or polychemotherapy), elimination of a source of permanent metastatic sowing thus leading to more efficient treatment.


2014 ◽  
Vol 41 (2) ◽  
pp. 9-12
Author(s):  
MM Rahman ◽  
MN Haque ◽  
MA Kadir ◽  
MR Kallol ◽  
Dr Wanaiza

Tuberculous cervical lymphadenitis (TCL) is not very uncommon in our country. A series of 60 cases was studied from 204 non- thyroid neck swelling which were selected from 20,558 patients attending in ENT department in Central Police Hospital and Mitford Hospital, Dhaka in 3 years. The incidence of TCL was 29.41% among the non- thyroid neck swelling and 0.3% from total number of patients attending in ENT department. The most vulnerable ago group was the second decade 38.33% with female preponderance ( Female male ratio was 2: 1). The common presentaions were neck swelling (100%), fever (66.67%), night sweat (50%). 50% cases were associated with pulmonary tuberculosis. Tuberculin test was positive in 73.34%. Maximum number of patients were from low socioeconomic class and BCG vaccination had a significant protective role (31.67% were vaccinated and 68.33% were one- vaccinated). On histopathology of cervical lymph nodes caseation necrosis was found in 85% of cases.DOI: http://dx.doi.org/10.3329/bmj.v41i2.18793 Bangladesh Medical Journal 2012 Vol. 41 No. 2: 9-12


2008 ◽  
Vol 51 (3) ◽  
pp. 181-184 ◽  
Author(s):  
Soubhagya R. Nayak ◽  
Ashwin Krishnamurthy ◽  
Latha V. Prabhu ◽  
Lakshmi Ramanathan ◽  
Mangala M. Pai ◽  
...  

The description of accessory phrenic nerve (APN) in the standard textbooks and available literature is vague and sometimes limited to few lines. The incidence of APN varies a great deal from 17.6 % to 80.9 % in the available literature. The aim of the present study was to calculate the incidence and variation of APN in Indian population. Material and methods: Forty five adult formalin-fixed cadavers (35 male, 10 female; 90 sides) used for gross anatomy dissection for undergraduates; during the 2 year period 2006–2007 were considered. Findings were recorded at different stages of the dissection. Results: Out of 90 body sides studied, the APN was present in 48 sides (53.3 %). In 17 of the above sides the APN was confined to the cervical region (Cervical type) and in 31 sides the APN entered the thorax (Thoracic type), all anterior to the subclavian vein (SV). In eleven specimens the APN was found bilaterally. Conclusion: The incidence of APN, with its course and relation to the various structures in cervical and thoracic region will help the surgeons while performing internal thoracic artery (ITA) grafting and other radical neck surgery.


Author(s):  
Nidhi Verma ◽  
Preeti Singh ◽  
Amod Kumar Saroj ◽  
Priya Gupta

The aim of this case report is to present as case of plasmacytoid at ectopic minor salivary gland in the neck which is a rare neoplasm with uncommon presentation of site. Usually it is a tumor of major salivary gland and more common in parotid gland and less common in the minor salivary gland of the oral cavity predominantly in palate. Here authors are discussing a case of 10-year-old female who presented in our institute with complain of swelling over right mid cervical region which was clinically suspected as reactive cervical lymph node. Patient was evaluated further and cytologically diagnosed as a case of plasmacytoid myoepithelioma. It was also confirmed as a case of plasmacytoid myoepithelioma after histopathology and immunohistochemistry studies. Plasmacytoid myoepithelioma at ectopic minor salivary gland site in the neck is uncommon presentation and only a limited number of cases have been reported in literature.


1970 ◽  
Vol 36 (2) ◽  
pp. 57-60 ◽  
Author(s):  
TAK Mahmud ◽  
HK Paul ◽  
ASM Zakaria ◽  
MA Rahman ◽  
MAJ Chowdhury

Background: Tuberculosis continues to be a health problem in many countries. There may be simultaneous multiple organ involvement. Diagnosis of one organ disease may lead to missing off diagnosis of other organ involvement.Objectives: The present study was done to analyze the association of cutaneous tuberculosis with pulmonary tuberculosis.Material and methods: Through purposive sampling a total of 23 patients of suspected cutaneous tuberculosis were primarily enrolled in this cross sectional study. History was taken and examinations were done to find out types of cutaneous lesions and to explore a pulmonary involvement. Investigations including CBC with ESR, Mantoux test and Skin biopsy were done for each and every patient. Those who had cutaneous tuberculosis on histopathology chest x-ray were done to detect pulmonary lesions. After investigations 2 patients were excluded due to absence of tubercular infection. Finally 21 patients were included in this study. Data were collected in a predesigned structured questionnaire.Results: Out of 21 patients 16 (76.19%) were male and 5(23.81%) were female with a male to female ratio of 3.2:1. Age range varies from 5-70 years with a mean of 29.76±18.2 years. MT was positive in 76.20% of patients. CXR showed 23.81% of the patients with cutaneous TB had simultaneous pulmonary involvement. The association is statistically significant (p<0.05).Conclusions: Patients with Cutaneous tuberculosis may have pulmonary involvement in a statistically significant number. In any patient with cutaneous TB, meticulous systemic examinations and relevant investigations have to be done to explore pulmonary involvement. DOI: 10.3329/bmrcb.v36i2.6988Bangladesh Med Res Counc Bull 2010; 36: 57-60


Author(s):  
Maria Inês Silva ◽  
Isabel Ferreira ◽  
Teresa Brandão ◽  
Paulo Telles de Freitas

Listeria monocytogenes is a gram positive bacillus responsible for listeriosis. This infection manifests mainly as bacteremia and / or central nervous system (CNS) infection. Involvement of other sites is rare. Pleural listeriosis is an uncommon presentation of L. monocytogenes infection and there is little data to guide the management of these patients. First-line antibiotics used empirically to treat bacterial respiratory infections are ineffective in treating these L. monocytogenes infections, which contributes to the progression of the infection and a worse prognosis. We present a case report of a patient admitted to an intensive care unit with septic shock secondary to systemic listeriosis with L. monocytogenes isolation in pleural fluid culture and blood cultures. The evolution of the hospitalization and the clinical outcome are reported.


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