Acceptance Rates and Beliefs toward COVID-19 Vaccination among the General Population of Pakistan: A Cross-Sectional Survey

Developing countries like Pakistan have previously suffered from barriers to acceptance of vaccination by the public because of financial and belief barriers. This study aims to explore these beliefs and highlight concerns regarding vaccine hesitancy in the general population of Pakistan since they are a hindrance to an effective coronavirus disease-19 (COVID-19) immunization in the country. A cross-sectional study was performed involving 1,778 participants from all four provinces of Pakistan. Results from the study showed more than half of the participants to be unsure of the safety (50%) and efficacy (51%) of the vaccine, whereas 42% were concerned about the side effects of the vaccine. About 72% of the respondents planned to get vaccinated, whereas 28% refused to do so. Internationally made imported vaccines were more trusted by the participants. Forty-four percent of the participants agreed to receive the vaccine upon recommendation from a physician. Lastly, participants who believed in the efficacy of the polio vaccination also considered the COVID-19 vaccine to be safe and effective.

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Acceptability of COVID-19 Vaccination in Herat, Afghanistan

10.21203/rs.3.rs-852218/v1 ◽

2021 ◽

Author(s):

Don Eliseo Lucero-Prisno III ◽

Ahmad Neyazi ◽

Attaullah Ahmadi ◽

Omid Tabesh ◽

Habibah Afzali ◽

...

Keyword(s):

General Population ◽

Cross Sectional Study ◽

Vaccine Hesitancy ◽

Sectional Study ◽

Cross Sectional ◽

Health Related ◽

Awareness Programs ◽

The Government ◽

To Receive ◽

Roll Out

Abstract Background: COVID-19 vaccine hesitancy is one of the major concerns in the roll out of vaccines in many countries. The aim of the study was to assess the level of COVID-19 vaccine acceptability among the population in Herat, Afghanistan, the third largest city in the country.Methods: This cross-sectional study was conducted between 15 April 2021 and 20 April 2021 among the general population of Herat City to examine the acceptability rate of COVID-19 vaccine. Sample size was calculated at 555. Different variables were collected using a questionnaire developed. Data were evaluated in IBM SPSS program.Results: Only 10.63% of the participants were willing to receive COVID-19 vaccine without having any concern and reservation. 45% were willing to receive the COVID-19 vaccine. 66.5% were concerned about the vaccine and its side effects and 29% were afraid of being infected by transmission of COVID-19 through the administration of vaccine on them.Conclusion: This research demonstrates that, concerns about the vaccine, myths and misinformation are widespread which will undermine the vaccination process. This study recommends the initiation of more health-related campaigns and awareness programs by the government for general population to enhance and expedite the roll out of COVID-19 vaccine.

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Predictors of Intention to Vaccinate against COVID-19 in the General Public in Hong Kong: Findings from a Population-Based, Cross-Sectional Survey

Vaccines ◽

10.3390/vaccines9070696 ◽

2021 ◽

Vol 9 (7) ◽

pp. 696

Author(s):

Elsie Yan ◽

Daniel W. L. Lai ◽

Vincent W. P. Lee

Keyword(s):

Hong Kong ◽

Health Belief ◽

Vaccine Safety ◽

Population Based ◽

Cross Sectional Study ◽

Vaccine Hesitancy ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Factors Associated ◽

To Receive

Vaccination is one of the most effective ways to stop the spread of COVID-19. Understanding factors associated with intention to receive COVID-19 vaccines is the key to a successful vaccination programme. This cross-sectional study explored the rate of vaccination intention and identified its predictors using the health belief model (HBM) in the general population in Hong Kong during the pandemic. Data were collected between December 2020 and January 2021 via telephone surveys. Hierarchical logistic regression analysis was used to identify factors associated with intention to receive COVID-19 vaccines. A total of 1255 adults (>18 years, 53% female) completed the telephone survey. Overall, 42% indicated an intention to vaccinate, 31.5% showed vaccine hesitancy, and 26.5% reported refusal to receive any COVID-19 vaccines. Individuals who were men, older in age, working, with past experiences of other pandemics, less concerned with the vaccine safety, with poorer knowledge about COVID-19, and having greater levels of perceived susceptibility, self-efficacy, cues to action, and acceptance of governmental preventive measures related to COVID-19 were significantly more likely to report an intention to vaccinate. The low intention among the Hong Kong population reflects the importance of developing effective vaccination promotion campaigns with the predictors identified in this study.

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COVID-19 Vaccine Hesitancy among the Public in Kuwait: A Cross-Sectional Survey

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18168836 ◽

2021 ◽

Vol 18 (16) ◽

pp. 8836

Author(s):

Jumana Alibrahim ◽

Abdelmoneim Awad

Keyword(s):

Family Members ◽

Vaccine Uptake ◽

Vaccine Hesitancy ◽

Multivariable Logistic Regression Analysis ◽

Snowball Sampling ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Major Barrier ◽

The Public ◽

To Receive

Vaccine hesitancy (uncertainty or unwillingness to receive vaccinations) is a major barrier to manage the COVID-19 pandemic in the long term. This study aimed to explore the prevalence of COVID-19 vaccine hesitancy among the public in Kuwait, to understand their attitudes towards vaccines in general, and to identify predictors of COVID-19 vaccine hesitancy. A cross-sectional study was conducted among 4147 adults aged ≥ 18 years. The snowball sampling strategy was used for data collection through social media and e-mails. A total of 3061 (73.8%) respondents indicated that they were vaccinated or intending to be vaccinated against the COVID-19 infection, while 1086 (26.2%) expressed their vaccine hesitancy. The most common reasons for vaccine hesitancy were the concerns about the vaccine’s possible side effects, its rushed development, and its efficacy in preventing the infection. Over half (57.2%) of respondents expressed intermediate to high levels of negative attitude towards vaccines in general. On the multivariable logistic regression analysis, the findings revealed that vaccine hesitancy was significantly more prevalent among respondents aged 30–64 years; females; married or divorced; residents of Hawalli, Al-Farwaniyah, Al-Jahra, and Mubarak Al-Kabeer; had intermediate monthly average income; non-smokers; not feeling worried about catching the infection; do not know whether any of their family members have been infected or died because of COVID-19 infection; do not have a large extent of confidence in the Kuwait health system’s ability to handle the pandemic; did not receive influenza vaccine during the last year; refused or elected to forego a doctor-recommended vaccine; did not receive adequate information from the public health authorities/healthcare providers about the COVID-19 vaccines; none of their first-degree family members received or were intending to receive the vaccine; and expressed intermediate to high levels of negative attitudes towards vaccines in general. The present findings provide a steer as to the groups that most need to be reached to increase the rates of vaccine uptake.

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Hesitancy Towards COVID-19 Vaccine Among Older People in Luzhou, China: A Cross-sectional Study

10.21203/rs.3.rs-757239/v1 ◽

2021 ◽

Author(s):

Jianlan Ren ◽

Yu Zheng ◽

Yue Luo ◽

Mei Li ◽

Rendie Xie ◽

...

Keyword(s):

Older People ◽

Low Cost ◽

The Elderly ◽

Cross Sectional Study ◽

Vaccine Hesitancy ◽

Natural Immunity ◽

Cross Sectional Survey ◽

Related Factors ◽

Cross Sectional ◽

The Public

Abstract Background:Vaccination is one of the most effective and low-cost health measures to prevent COVID-19. Vaccine hesitancy is an obstacle to COVID-19 vaccination. Objective:This study aims to inform the vaccine hesitancy and analyze related factors towards COVID-19 vaccination among elderly in Luzhou, so as to provide suggestions for increasing vaccines uptake. Methods:A face-to-face questionnaire cross-sectional survey was conducted among the elderly people over 60 years old in Luzhou City in April 2021 by multi-stage sampling method. Results: A total of 1047 valid questionnaires were received. 42.0%（440/1047）vaccine hesitancy was reported among elderly in total. Female (OR=1.282, 95%CI:1.003-1.649), live in the rural (OR=3.659, 95%CI:2.813-4.758), poor health (OR=2.318, 95%CI:1.473-3.649), individuals not having regular medical check-ups (OR=2.669, 95%CI:2.072-3.437) and no history of self-funded influenza vaccination ( OR=2.408, 95% CI:1.656-3.502) reported slightly higher vaccine hesitancy. Being in low-risk areas and no need to get vaccinated (OR=16.877, 95%CI:11.750-24.242), being considered that the current protective measures had been able to avoid infection (OR=5.539, 95%CI:3.596-8.532), being considered that the natural immunity get from the disease was better than getting COVID-19 vaccine (OR=5.297, 95%CI:3.666-7.653), being concerned about side effects (OR=5.155, 95%CI:3.655-7.270) and being concerned that the vaccine was ineffective (OR=10.244, 95%CI:6.831-15.362) had higher prevalence of vaccine hesitancy. Those who believing the COVID-19 vaccine was safe and reliable (OR=0.075, 95%CI:0.044-0.130), the vaccine was free (OR=0.466, 95%CI:0.312-0.697) and individuals with higher education (OR=0.189, 95%CI:0.126-0.284) were more willing to get vaccinated. Conclusion: Confidence in vaccines and perceptions of benefits and risk are associated with vaccine hesitancy. It’s very important to strengthen vaccine health literacy education for older people and enhance vaccine confidence. Countries need to supervise the public opinions in social media, television broadcasting and other media, so as to ensure the correct orientation of public opinion. Open and transparent evidence-based information is also needed which can help improve the vaccination coverage rate of the public.

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COVID-19 Vaccination Intent and Willingness to Pay in Bangladesh: A Cross-Sectional Study

Vaccines ◽

10.3390/vaccines9050416 ◽

2021 ◽

Vol 9 (5) ◽

pp. 416

Author(s):

Russell Kabir ◽

Ilias Mahmud ◽

Mohammad Tawfique Hossain Chowdhury ◽

Divya Vinnakota ◽

Shah Saif Jahan ◽

...

Keyword(s):

General Population ◽

Willingness To Pay ◽

Health Beliefs ◽

Health Belief ◽

Cross Sectional Study ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Sociodemographic Variables ◽

Belief Model ◽

To Receive

This article reports the intent to receive a SARS-COV-2 vaccine, its predictors and willingness to pay in Bangladesh. We carried out an online cross-sectional survey of 697 adults from the general population of Bangladesh in January 2021. A structured questionnaire was used to assess vaccination intent. The questionnaire included sociodemographic variables and health belief model constructs which may predict vaccination intent. Among the participants, 26% demonstrated a definite intent, 43% probable intent, 24% probable negative, and 7% a definite negative intention. Multivariable logistic regression analyses suggest an association between definite intent and previous COVID-19 infection (OR: 2.86; 95% CI: 1.71–4.78), perceiving COVID-19 as serious (OR: 1.93; 1.04–3.59), the belief that vaccination would make them feel less worried about catching COVID-19 (OR: 4.42; 2.25–8.68), and concerns about vaccine affordability (OR: 1.51; 1.01–2.25). Individuals afraid of the side effects (OR: 0.34; 0.21–0.53) and those who would take the vaccine if the vaccine were taken by many others (OR: 0.44; 0.29–0.67) are less likely to have a definite intent. A definite negative intent is associated with the concern that the vaccine may not be halal (OR: 2.03; 1.04–3.96). Furthermore, 68.4% are willing to pay for the vaccine. The median amount that they are willing to pay is USD 7.08. The study findings reveal that the definite intent to receive the SARS-CoV-2 vaccination among the general population varies depending on their COVID-19-related health beliefs and no significant association was found with sociodemographic variables.

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Intention of Healthcare Workers to Receive COVID-19 Vaccine: A Cross-Sectional Survey in 10 Countries in Eastern Mediterranean Region

10.1101/2021.03.20.21253892 ◽

2021 ◽

Author(s):

Yasir Ahmed Mohammed Elhadi ◽

Azza Mehanna ◽

Yusuff Adebayo Adebisi ◽

Mohammad Yasir Essar ◽

Haider M El Saeh ◽

...

Keyword(s):

Mediterranean Region ◽

Healthcare Workers ◽

Online Survey ◽

Health Workers ◽

Eastern Mediterranean ◽

Eastern Mediterranean Region ◽

Cross Sectional Study ◽

Cross Sectional Survey ◽

Cross Sectional ◽

To Receive

Background: Healthcare workers intention to be vaccinated is an important factor to be consider for successful COVID-19 vaccination programme. Our study aimed to understand the intention of health workers to receive COVID-19 vaccine and associated concerns across 10 countries in Eastern Mediterranean Region (EMRO). Method: A cross-sectional study was conducted in January 2021 among healthcare workers using an online survey. A total of 2806 health workers (physicians, nurses and pharmacists) completed and returned the informed consent along with the questionnaire electronically. Data were analyzed using IBM SPSS software package version 20.0. Results: More than half of the respondents (58.0%) intend to receive COVID-19 vaccine, even if the vaccination is not mandatory for them. On the other hand, 25.7% of respondents were not intending to undertake COVID-19 vaccination while 16.3 % answered undecided. The top three reasons for not intending to be vaccinated were unreliability of COVID-19 vaccine clinical trials (62.0%), fear of the side effects of the vaccine (45.3%), and that COVID-19 vaccine will not give immunity for a long period of time (23.1%). Conclusion: Overall, our study revealed suboptimal acceptance of COVID-19 vaccine among healthcare workers in the 10 countries in EMRO.

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Early COVID-19 Vaccination of Romanian Medical and Social Personnel

Vaccines ◽

10.3390/vaccines9101127 ◽

2021 ◽

Vol 9 (10) ◽

pp. 1127

Author(s):

Loredana Sabina Cornelia Manolescu ◽

Corneliu Nicolae Zaharia ◽

Anca Irina Dumitrescu ◽

Irina Prasacu ◽

Mihaela Corina Radu ◽

...

Keyword(s):

General Population ◽

Medical Profession ◽

Geographic Area ◽

Cross Sectional Study ◽

Vaccine Virus ◽

Medical Doctor ◽

Vaccine Hesitancy ◽

Cross Sectional ◽

Vaccine Acceptance ◽

First Choice

Background: In December 2020, the first doses of COVID-19 vaccines arrived in Romania and were made available to medical and social staff. Vaccine hesitancy appeared as a barrier to effectively ending the pandemic. The opinions of medical and social staff influence the opinion of the general population. This study assesess the attitudes, knowledge, and opinion of medical and social personnel toward COVID-19 vaccines and vaccination and the influencing factors. Methods: 1025 persons participated in an online cross-sectional study from March until July 2021. Results: Out of 1021 eligible responders, 719 (70.42%) had been vaccinated: 227 with one dose (22.23%) and 492 with two doses (48.18%). There were 302 responders who were not vaccinated at all. Out of them, 188 refused vaccinations. The participants showed a good understanding and knowledge of SARScoV-2 transmission and treatment. Geographic area, medical profession, and medical experience influenced COVID-19 vaccination (p < 0.001). There were no associations between willingness to vaccinate and vaccine/virus knowledge. Most of the responders who were vaccinated or wanted to be vaccinated indicated an mRNA vaccine as their first choice. The variables that were significantly associated with reporting COVID-19 vaccine acceptance after logistic regression were: living in an urban area (Ora = 1.58, 95% CI: 0.98–2.56), being female (Ora = 1.59; 95% CI:1.03–2.44), and being a medical doctor (Ora = 3.40; 95% CI: 1.84–6.26). Conclusions: These findings show that vaccine hesitancy persists in medical and social personnel in Romania, and, hence, it may be reflected in the hesitancy of the general population toward vaccination.

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1172. SARS-CoV-2 Vaccine Hesitancy in Caregivers of Hospitalized Children

Open Forum Infectious Diseases ◽

10.1093/ofid/ofab466.1365 ◽

2021 ◽

Vol 8 (Supplement_1) ◽

pp. S677-S677

Author(s):

Marisa Orbea ◽

Rachel Cunningham ◽

C Mary Healy ◽

Julie A Boom ◽

Claire Bocchini

Keyword(s):

Vaccine Uptake ◽

Vaccine Hesitancy ◽

Hospitalized Children ◽

Parent Attitudes ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Vaccine Acceptance ◽

And Behaviors ◽

Childhood Vaccines ◽

To Receive

Abstract Background SARS-CoV-2 vaccine hesitancy (VH) is hindering nationwide vaccination efforts; little is known about caregiver SARS-CoV-2 vaccine acceptance for children. We aimed to identify associations with SARS-CoV-2 VH in caregivers of hospitalized children. Methods We conducted a prospective cross-sectional survey in English and Spanish of caregiver COVID-19 knowledge, attitudes, behaviors, and associated VH among hospitalized children 6 months - 18 years at a large pediatric medical institution. Parents were approached daily, averaging 4-5 days/week, from 12/8/2020--4/5/2021. VH was assessed using the Parent Attitudes about Childhood Vaccines (PACV) survey; PACV score ≥50 denoted VH. Descriptive statistics and multivariable logistic regression were used. Responses were categorized. Results 295/307 (96%) of approached caregivers enrolled; 79% were ≥ 30 years, 68% were married/ living with a partner, and 57% had at least some college. 36% identified as white, 19% Black, and 46% Hispanic/ Latino. 53% of caregiver children had public insurance. 91% of caregivers self-reported their children were up to date with routine vaccines. 17% of caregivers were vaccine-hesitant overall. 50% of caregivers were willing to receive COVID-19 vaccine themselves. Figure 1 shows intention to vaccinate their child by PACV score. 65% knew someone who was hospitalized for COVID-19. 67% were scared of their child getting COVID-19. However, 49% were scared of their child getting the vaccine, 28% did not want to vaccinate their child and 27% were neutral in the intention to vaccinate their child. Caregivers who did not intend to vaccinate their child were more likely to be Black (27% vs. 16%, p=0.04) and less likely to be Hispanic/ Latino (33% vs. 49%, p=0.02). Table 1 shows attitudes, beliefs, and behaviors surrounding the COVID-19 pandemic and vaccine in caregivers who did or did not intend to vaccinate their child. Figure 1 COVID-19 vaccine uptake by PACV score Table 1 Caregiver attitudes, beliefs, and behaviors surrounding the COVID-19 pandemic and the COVID-19 vaccine Conclusion The majority of caregivers believe that SARS-CoV-2 vaccine will help control the pandemic, but less than half plan to vaccinate their children. A quarter of caregivers expressed uncertainty regarding the vaccine and therefore may be amenable to education and discussion. COVID-19 VH is different from VH towards routine vaccinations. More research is needed to address COVID-19 specific VH. Disclosures C. Mary Healy, MD, Dexcom (Shareholder)Intuitive (Shareholder)Quidel Corporation (Shareholder)Up to Date (Other Financial or Material Support, Honorarium)Vapotherm (Shareholder)

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Acceptability of the Coronavirus Disease-2019 Vaccine Among Medical Students in Uganda: a Cross Sectional Study.

10.21203/rs.3.rs-425207/v1 ◽

2021 ◽

Author(s):

Andrew Marvin Kanyike ◽

Ronald Olum ◽

Jonathan Kajjimu ◽

Daniel Ojilong ◽

Grabriel Madut Akech ◽

...

Keyword(s):

Medical Students ◽

Perceived Risk ◽

Cross Sectional Study ◽

Vaccine Hesitancy ◽

Cross Sectional Survey ◽

Future Health ◽

Vaccine Acceptability ◽

Cross Sectional ◽

The Future ◽

Global Threat

Abstract Background COVID-19 is still a major global threat and vaccination remains the long-lasting solution. Unanimous uptake of the COVID-19 vaccine is required to subsequently avert its spread. We therefore, assessed COVID-19 vaccine acceptability, hesitancy, and associated factors among medical students in Uganda. Methods This study employed an online descriptive cross-sectional survey among medical students across 10 medical schools in Uganda. A structured questionnaire as a Google form was sent to participants via WhatsApp. Data was extracted and analyzed using Microsoft Excel 2016 and STATA 16. Descriptive statistics, bivariate and multivariable analyses were performed. Results We surveyed 600 medical students, 377 (62.8%) were male. COVID-19 vaccine hesitancy and acceptability were 30.7% and 37.3%, respectively. Factors associated with vaccine acceptability were being female (aOR = 1.9, 95% CI: 1.3–2.9, p = 0.001), being single (aOR = 2.1, 95% CI 1.1–3.9, p = 0.022). Very high (aOR = 3.5, 95% CI 1.7–6.9, p < 0.001) or moderate (aOR = 2.2, 95% CI 1.2–4.1, p = 0.008) perceived risk of getting COVID-19 in the future, receiving any vaccine in the past 5 years (aOR = 1.6, 95% CI 1.1–2.5, p = 0.017), and COVID-19 vaccine hesitancy (aOR 0.6, 95% CI 0.4–0.9, p = 0.036). Conclusions This study revealed low levels of acceptance towards the COVID-19 vaccine among medical students, low self-perceived risks of COVID-19, and many had relied on social media that provided them with negative information. This poses an evident risk on the battle towards COVID-19 in the future especially when these future health professions are expected to be influencing decisions of the general public towards the same.

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Myths, beliefs, and conspiracies about COVID-19 Vaccines in Sindh, Pakistan: An online cross-sectional survey

10.22541/au.161519250.03425961/v1 ◽

2021 ◽

Author(s):

Qamar Abbas ◽

Fatima Mangrio ◽

Sunil Kumar

Keyword(s):

Side Effects ◽

Cross Sectional Study ◽

Vaccine Uptake ◽

Cross Sectional Survey ◽

Chi Square ◽

Cross Sectional ◽

Web Based ◽

Major Barrier ◽

Polio Vaccination ◽

Relationship Of

Abstract Background Pakistan has already encountered intense opposition to polio vaccination due to myths and misinformation, now the unfavorable opinions of COVID-19 vaccinations among the population would have catastrophic consequences for attempts to end the pandemic. Methods A web-based cross-sectional study was conducted in the general population of Sindh, Pakistan in January 2021. 31 items based on vaccines availability, safety, and myths, the questionnaire was designed and randomly distributed through a google form link. Results were analyzed using descriptive and Chi-square tests. Results A total of 774 responses were recorded from 23 districts of Sindh, Pakistan. The majority of participants (n=00, 00.0%) were not aware of the presence of the COVID-19 vaccine in Pakistan. Results found the significant relationship of conspiracies and myths with an education level of participants, to make Muslims infertile, illiterate showed (Yes n=45, No=27) while postgraduate (Yes n=11, No=88) (χ2 = 109.6, P> 0.000). Participants showed doubt about the safety of vaccines, (Yes n= 464, 59.9%, No= 310, 40.1%). Other responses related to side effects of the vaccine were also highly significant, participants showed that vaccine side effects (Yes n= 462, 59.7%, No= 312, 40.3%), Pregnant or breastfeeding women should not get vaccinated (Yes n= 468, 59.8%, No= 311, 40.1%) and people with underlying conditions should not get vaccinated (True n= 389, 50.3%, False= 385, 49.7%). Conclusion The proportion of varying public doubts in vaccines’ safety and efficacy and the presence of myths, conspiracies will be a major barrier to vaccine uptake.

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