scholarly journals The effect of a fixed non-mineral oil on the antibacterial activity of ampicillin trihydrate against resistant clinical strains of Staphylococcus aureus

2010 ◽  
Vol 6 (2) ◽  
Author(s):  
OE Adeleke ◽  
JO Olaitan
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Mineral Oil ◽  
Clinical Strains ◽  
Ampicillin Trihydrate

scholarly journals Highly effective silver oxides: influence of oxygen concentration on antibacterial activity against clinical strains of Staphylococcus aureus

2021 ◽  
Vol 5 ◽  
pp. 54-60
Author(s):  
E.M. Gordina ◽  
◽  
S.A. Bozhkova ◽  
A.A. Erusin ◽  
◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Silver Oxide ◽  
Clinical Strains ◽  
Ion Plasma ◽  
Manual Methods ◽  
Subsequent Measurement ◽  
Minimum Ratio ◽  
Density Results ◽  
Metallic Target

Aim of study. Comparative analysis of antibacterial activity of silver oxides (Ag0,2O, Ag1 O, Ag2 O) in relation to clinical strains of Staphylococcus aureus obtained from patients with orthopaedic infection. Material and methods. Films of silver oxides were coated on paper surface in vacuum via the method of ion-plasma arc sputtering of the metallic target. Isolation of S.aureus was performed via standard manual methods from January to June 2021, identification was carried out via the MALDI-TOF-MS method. Sensitivity to antibiotics was evaluated according to EUCAST (2021, v.11.0) requirements. Antibacterial activity of the silver oxide samples obtained against 130 clinical strains of S.aureus was analysed in liquid nutrient broth with subsequent measurement of optical density. Results. Over 90% of the clinical strains of S.aureus isolated from patients with orthopaedic infection were sensitive to the silver oxides obtained. The amount of oxygen in the compound exerted almost no influence on the sensitivity to the oxides: even a minimum ratio between silver and oxygen provided a pronounced antibacterial effect. Additionally, the sensitivity to silver oxides did not depend on the MRSA resistance phenotype and the compounds were effective against XDR strains of S.aureus in 96.7% of the cases. Conclusion. All tested samples of silver oxides (Ag0,2O, Ag1 O, Ag2O) were characterised by pronounced antibacterial activity against S. aureus. The data obtained point to prospects in application of silver oxides for prevention and treatment of orthopaedic infection induced by Staphylococcus aureus without regard for the sensitivity phenotype of the pathogen.

scholarly journals Antibacterial Activity of Protocatechuic Acid Ethyl Ester on Staphylococcus aureus Clinical Strains Alone and in Combination with Antistaphylococcal Drugs

Molecules ◽  
2015 ◽  
Vol 20 (8) ◽  
pp. 13536-13549 ◽  
Author(s):  
Maria Miklasińska ◽  
Małgorzata Kępa ◽  
Robert Wojtyczka ◽  
Danuta Idzik ◽  
Anna Zdebik ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Ethyl Ester ◽  
Protocatechuic Acid ◽  
Acid Ethyl Ester ◽  
Clinical Strains

Antibacterial Activity of Desert Truffles from Saudi Arabia Against Staphylococcus aureus and Pseudomonas aeruginosa

2017 ◽  
Vol 19 (2) ◽  
pp. 121-125 ◽  
Author(s):  
Domenico Schillaci ◽  
Maria Grazia Cusimano ◽  
Stella Maria Cascioferro ◽  
Vita Di Stefano ◽  
Vincenzo Arizza ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Saudi Arabia ◽  
Desert Truffles

Antibacterial Activity of Thujaoccidentalis,ThujaorientalisandChamaecyparisobtusa

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Kyoung- Sun Seo ◽  
Seong Woo Jin ◽  
Seongkyu Choi ◽  
Kyeong Won Yun
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Antibacterial Agent ◽  
Methanol Extract ◽  
The Other ◽  
Diffusion Method ◽  
E Coli ◽  
Agar Diffusion ◽  
Agar Diffusion Method ◽  
Crude Methanol Extract

The antibacterial activity of three Cupressaceae plants (Thujaoccidentalis,ThujaorientalisandChamaecyparisobtusa) was tested against three bacteria using the agar diffusion method. The ether and ethylacetate fraction of crude methanol extract from the three plants showed potent antibacterial activity against the tested microorganisms. The result showed that Staphylococcus aureus revealed the most sensitivity among the tested bacteria. Thujaoccidentalisether fraction and Thujaorientalis hexane fraction exhibited the highest antibacterial activity against Staphylococcus aureus. E. coli was shown the highest MIC values compared to the other two tested bacteria, which indicates the lowest antibacterial activity against the bacterium. This study promises an interesting future for designing a potentially active antibacterial agent from the three Cupressaceae plants.

Chemical Composition and Antibacterial Activity of Essential Oils of Three Medicinal Plants from Algerian Semi-Arid Climatic Zone

2018 ◽  
Vol 16 (S1) ◽  
pp. S155-S163 ◽  
Author(s):  
S. Mehalaine ◽  
O. Belfadel ◽  
T. Menasria ◽  
A. Messaili
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Rosmarinus Officinalis ◽  
Salvia Officinalis ◽  
Thymus Algeriensis

The present study was carried out to determine, for the first time, the chemical composition and antibacterial activity of essential oils derived from the aerial parts of three aromatic plants Thymus algeriensis Boiss & Reut, Rosmarinus officinalis L., and Salvia officinalis L. growing under semiarid conditions. The essential oils were chemically analyzed and identified by gas chromatography (GC) and GC/ mass spectrometry (GC/MS) and their antimicrobial activity was individually evaluated against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa using both agar disk diffusion and agar dilution methods. The major constituents of Thymus algeriensis essential oil were identified as camphor (13.62%), 1,8-cineol (6.00%), borneol (5.74%), viridiflorol (4.00%), and linalool (3.93%). For Rosmarinus officinalis essential oil, 48 compounds were characterized, of which the main constituents were camphor (17.09%), Z-β-ocimene (10.88%), isoborneol (9.68%), α-bisabolol (7.89%), and borneol (5.11%). While, Salvia officinalis essential oil was characterized by β-thujone (16.44%), followed by viridiflorol (10.93%), camphor (8.99%), 1,8-cineol (8.11%), trans-caryophyllene (5.85%), and α-humulene (4.69%) as the major components. Notably, results from antibacterial screening indicated that Thymus algeriensis and Salvia officinalis essential oils exhibited a strong inhibitory effect against both Escherichia coli and Staphylococcus aureus compared to Rosmarinus officinalis essential oil. Further, less activity was recorded against Pseudomonas aeruginosa for the three tested essential oils.

Complexes of Cu (II) with a-Ketoglutaric Acid and 1- (o-tolyl) Biguanide Synthesis, characterization and biological Activity

2019 ◽  
Vol 70 (10) ◽  
pp. 3603-3610
Author(s):  
Madalina Mihalache ◽  
Cornelia Guran ◽  
Aurelia Meghea ◽  
Vasile Bercu ◽  
Ludmila Motelica ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Biological Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Copper Complexes ◽  
Substrate Adhesion ◽  
Inert Substrate

The three copper complexes having a-ketoglutaric acid (H2A) and 1- (o-tolyl) biguanide (TB) ligands have been synthesized and characterized. The proposed formulas for these complexes are: [Cu(TB)(HA)]Cl (C1), [Cu(TB)(HA)CH3COO]�H2O (C2) and [Cu(TB)(HA)](NO3) (C3) where HA represents deprotonated H2A. The complexes obtained were tested for antibacterial activity against Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 27853, antifungal activity on Candida albicans ATCC 10231 and antitumor activity on HeLa tumor cells. Due to the antitumor, antifungal, antimicrobial activity and inhibition of inert substrate adhesion, complexes synthesized could be used for potential therapeutic applications.

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