Ecological Survey of Plesiomonas Shigelloides

1993 ◽  
Vol 56 (5) ◽  
pp. 444-446 ◽  
Author(s):  
SAM D. ABBEY ◽  
NEDIE P. EMERINWE ◽  
M. PHILL ◽  
EMMANUEL N. AMADI
Keyword(s):  
Incidence Rate ◽  
Plesiomonas Shigelloides ◽  
Fecal Samples ◽  
Ecological Survey ◽  
Port Harcourt ◽  
Microbiological Methods ◽  
High Incidence ◽  
Low Incidence ◽  
Different Origins ◽  
Soil And Water

In order to establish the presence and distribution of Plesiomonas shigelloides in the Port Harcourt area, samples from different origins were examined. Standard microbiological methods were adopted for the analysis. The results showed a relatively high incidence in soil and water which are speculated to be reservoirs of the organism. A low incidence rate occurred in seafoods and humans. No P. shigelloides was detected from cattle and poultry. Although the isolation in humans was low 2.0% (8 of 400), five samples yielded P. shigelloides as the only enteropathogen. Four of the five were from diarrheic fecal samples, thus indicating the involvement of P. shigelloides in diarrhea.

scholarly journals A genome epidemiological study of mycobacterium tuberculosis in subpopulations with high and low incidence rate in Guangxi, South China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dingwen Lin ◽  
Junning Wang ◽  
Zhezhe Cui ◽  
Jing Ou ◽  
Liwen Huang ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Incidence Rate ◽  
South China ◽  
Demographic History ◽  
Lineage Differentiation ◽  
A Genome ◽  
High Incidence ◽  
History Of ◽  
Lineage 2 ◽  
Low Incidence

Abstract Background Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis (Mtb). China is the third in top 8 high TB burden countries and Guangxi is one of the high incidence areas in South China. Determine bacterial factors that affected TB incidence rate is a step toward Ending the TB epidemic. Results Genomes of M. tuberculosis cultures from a relatively high and low incidence region in Guangxi have been sequenced. 347 of 358(96.9%) were identified as M. tuberculosis. All the strains belong to Lineage 2 and Lineage 4, except for one in Lineage 1. We found that the genetic structure of the M. tuberculosis population in each county varies enormously. Low incidence rate regions have a lower prevalence of Beijing genotypes than other regions. Four isolates which harbored mutT4-48 also had mutT2-58 mutations. It is suggested that strains from the ancestors of modern Beijing lineage is circulating in Guangxi. Strains of modern Beijing lineage (OR=2.04) were more likely to acquire drug resistances than Lineage 4. Most of the lineage differentiation SNPs are related to cell wall biosynthetic pathways. Conclusions These results provided a higher resolution to better understand the history of transmission of M. tuberculosis from/to South China. And the incidence rate of tuberculosis might be affected by bacterial population structure shaped by demographic history. Our findings also support the hypothesis that Modern Beijing lineage originated in South China.

scholarly journals Tuberculosis reinfection rate as a proportion of total infection rate correlates with the logarithm of the incidence rate: a mathematical model

2008 ◽  
Vol 6 (30) ◽  
pp. 11-15 ◽  
Author(s):  
Pieter W Uys ◽  
Paul D van Helden ◽  
John W Hargrove
Keyword(s):  
Incidence Rate ◽  
Empirical Data ◽  
Incidence Rates ◽  
Simple Relationship ◽  
A Value ◽  
High Incidence ◽  
Low Incidence ◽  
First Time ◽  
The Relationship ◽  
Range Of Values

In a significant number of instances, an episode of tuberculosis can be attributed to a reinfection event. Because reinfection is more likely in high incidence regions than in regions of low incidence, more tuberculosis (TB) cases due to reinfection could be expected in high-incidence regions than in low-incidence regions. Empirical data from regions with various incidence rates appear to confirm the conjecture that, in fact, the incidence rate due to reinfection only, as a proportion of all cases, correlates with the logarithm of the incidence rate, rather than with the incidence rate itself. A theoretical model that supports this conjecture is presented. A Markov model was used to obtain a relationship between incidence and reinfection rates. It was assumed in this model that the rate of reinfection is a multiple, ρ (the reinfection factor), of the rate of first-time infection, λ . The results obtained show a relationship between the proportion of cases due to reinfection and the rate of incidence that is approximately logarithmic for a range of values of the incidence rate typical of those observed in communities across the globe. A value of ρ is determined such that the relationship between the proportion of cases due to reinfection and the logarithm of the incidence rate closely correlates with empirical data. From a purely theoretical investigation, it is shown that a simple relationship can be expected between the logarithm of the incidence rates and the proportions of cases due to reinfection after a prior episode of TB. This relationship is sustained by a rate of reinfection that is higher than the rate of first-time infection and this latter consideration underscores the great importance of monitoring recovered TB cases for repeat disease episodes, especially in regions where TB incidence is high. Awareness of this may assist in attempts to control the epidemic.

scholarly journals Transmissibility of hand, foot, and mouth disease in 97 counties of China.

2021 ◽  
Author(s):  
Wei Zhang ◽  
Jia Rui ◽  
Xiaoqing Cheng ◽  
Bin Deng ◽  
Hesong Zhang ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Jiangsu Province ◽  
Asia Pacific ◽  
Seasonal Characteristics ◽  
High Incidence ◽  
Foot And Mouth ◽  
Low Incidence ◽  
Serious Disease

Abstract Background Hand, foot, and mouth disease (HFMD) has been a serious disease burden in the Asia Pacific region represented by China, and the transmission characteristics of HFMD in regions haven’t been clear. This study calculated the transmissibility of HFMD at county levels in Jiangsu Province, China, analyzed the differences of transmissibility and explored the reasons. Methods We built susceptible-exposed-infectious-asymptomatic-removed (SEIAR) model for seasonal characteristics of HFMD, estimated effective reproduction number (Reff) by fitting the incidence of HFMD in 97 counties of Jiangsu Province from 2015 to 2020, compared incidence rate and transmissibility in different counties by non -parametric test, rapid cluster analysis and rank-sum ratio. Results The average daily incidence rate was between 0 and 4 per 100,000 in Jiangsu province from 2015–2020. The 97 counties could be divided into three levels: low incidence, medium incidence and high incidence, and occurred that the average daily incidence rate dropped sharply in 2016–2017, and increased sharply in 2017–2018 years. The Quartile of Reff in Jiangsu Province from 2015 to 2020 was 1.54 (0.49, 2.50), Rugao district in Central Jiangsu and Jianhu district in Northern Jiangsu had the highest transmissibility by rank-sum ratio. Reff generally decreased in 2017 and increased in 2018 in most counties, and the median level of Reff was lowest in 2017 (P < 0.05). Conclusion Transmissibility was different in 97 counties of Jiangsu Province, and the reasons for the differences may be related to the climate, demographic characteristics, virus subtypes, vaccination and other infectious diseases.

scholarly journals Transmissibility of Hand, Foot, and Mouth Disease in 97 Counties of Jiangsu Province, China, 2015- 2020

2021 ◽  
Author(s):  
Wei Zhang ◽  
Jia Rui ◽  
Xiaoqing Cheng ◽  
Bin Deng ◽  
Hesong Zhang ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Jiangsu Province ◽  
Asia Pacific ◽  
Seasonal Characteristics ◽  
High Incidence ◽  
Foot And Mouth ◽  
Low Incidence ◽  
Serious Disease

Abstract Background: Hand, foot, and mouth disease (HFMD) has been a serious disease burden in the Asia Pacific region represented by China, and the transmission characteristics of HFMD in regions haven’t been clear. This study calculated the transmissibility of HFMD at county levels in Jiangsu Province, China, analyzed the differences of transmissibility and explored the reasons.Methods: We built susceptible-exposed-infectious-asymptomatic-removed (SEIAR) model for seasonal characteristics of HFMD, estimated effective reproduction number (Reff) by fitting the incidence of HFMD in 97 counties of Jiangsu Province from 2015 to 2020, compared incidence rate and transmissibility in different counties by non -parametric test, rapid cluster analysis and rank-sum ratio.Results: The average daily incidence rate was between 0 and 4 per 100,000 in Jiangsu province from 2015-2020. The 97 counties could be divided into three levels: low incidence, medium incidence and high incidence, and occurred that the average daily incidence rate dropped sharply in 2016-2017, and increased sharply in 2017-2018 years. The Quartile of Reff in Jiangsu Province from 2015 to 2020 was 1.54 (0.49, 2.50), Rugao district in Central Jiangsu and Jianhu district in Northern Jiangsu had the highest transmissibility by rank-sum ratio. Reff generally decreased in 2017 and increased in 2018 in most counties, and the median level of Reff was lowest in 2017 (P<0.05).Conclusion: Transmissibility was different in 97 counties of Jiangsu Province, and the reasons for the differences may be related to the climate, demographic characteristics, virus subtypes, vaccination and other infectious diseases.

scholarly journals Spatial distribution and risk assessment of toxic metals in agricultural soils from endemic nasopharyngeal carcinoma region in South China

2020 ◽  
Vol 12 (1) ◽  
pp. 568-579
Author(s):  
Liping Mo ◽  
Yongzhang Zhou ◽  
Gnanachandrasamy Gopalakrishnana ◽  
Xingyuan Li
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
South China ◽  
Toxic Metals ◽  
Agricultural Soils ◽  
Hazard Index ◽  
Toxic Metal ◽  
Carcinogenic Risk ◽  
Pollution Indices ◽  
High Incidence ◽  
Low Incidence

AbstractSihui city (South China) is much affected by nasopharyngeal carcinoma (NPC). To investigate the relationships between the toxic metals in soil and NPC incidence in Sihui, 119 surface soil samples were collected from agricultural fields and analyzed. The soil As–Cr contents in Longjiang (high-incidence area) are significantly lower than those in Weizheng and Jianglin (low-incidence areas), whereas the soil Pb content in Longjiang is significantly higher than that in Weizheng. The Nemerow pollution indices (PIN) of soils decrease in the order of Jianglin > Weizheng > Longjiang. The enrichment factor (EF) of Cd indicates that the Cd enrichment is contributed by human activities. Potential toxic metal-related ecological risk values decrease in the order of Jianglin > Weizheng > Longjiang. The mean hazard index (HI) value of Longjiang was lower than those of Weizheng and Jianglin. There are no adverse noncarcinogenic health effects of soil toxic metals to adults in the study areas. Carcinogenic risks of As and Cr via ingestion and dermal contact and total carcinogenic risk are within the warning range, from 10−6 to 10−4. Hence, we suggest that toxic metals in the soil may not be major geochemical carcinogenic factors of high NPC incidence in Sihui.

scholarly journals Epidemiology of Thyroid Carcinomas in North Macedonia (1999-2015)

2021 ◽  
Vol 12 ◽  
pp. 215013272110042
Author(s):  
Makazlieva Tanja ◽  
Vaskova Olivija ◽  
Stojanoski Sinisha ◽  
Manevska Nevena ◽  
Miladinova Daniela ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Prevalence Rate ◽  
Epidemiological Data ◽  
Female Gender ◽  
The Elderly ◽  
Inclusion Criteria ◽  
Statistical State ◽  
Total Prevalence ◽  
Low Incidence ◽  
Histopathological Type

Objective: We have set as objective to analyze epidemiological data of diagnosed thyroid carcinoma (TC) cases, incidence and prevalence rate by gender, age, histopathological type, and statistical regions in R. of N. Macedonia during the period 1999 to 2015. Material and Methods: Retrospective analysis of medical data collected from the 2 state thyroid departments. Inclusion criteria included newly diagnosed cases of TC in appropriate years for the period 1999 to 2015. We have evaluated: yearly incidence rate, incidence and prevalence by gender, age, the distribution in 8 statistical state regions and histopathological types and subtypes representation. Results: A total number of 422 TC patients were detected, average incidence rate of 1.22/105, with most prevalent papillary TCs79.5%, followed by follicular 10.9%, medullar 4.1%, anaplastic 3.1%, and other rare types with 2.3%. The highest incidence rate was detected in Skopje region, while the lowest in Southeast and the Polog region. The total prevalence rate for the female gender was 32.61/104 and for male 9.27/104 (f/m ratio = 3.52:1), with lowest female/male difference found in the elderly > 65 years (f/m = 2.21/1). Conclusion: Compared with regional epidemiological data we can conclude that Republic of N. Macedonia has very low incidence and prevalence rate, while female/male ratio was similar to that described in the literature. Our low incidence and prevalence rate may be due to 2 possible reasons, 1 would be insufficient diagnosis of only small portion of the real cases in the population, or the second reason may be a real low incidence resulting of specific etiopathogenetic circumstances.

scholarly journals Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview

2021 ◽  
Vol 22 (8) ◽  
pp. 3822
Author(s):  
Riccardo Di Fiore ◽  
Sherif Suleiman ◽  
Francesca Pentimalli ◽  
Sharon A. O’Toole ◽  
John J. O’Leary ◽  
...  
Keyword(s):  
Female Genital Tract ◽  
Germ Cell Tumors ◽  
Delayed Diagnosis ◽  
Public Health Issue ◽  
Gene Promoters ◽  
Gynecological Cancers ◽  
High Incidence ◽  
Low Incidence ◽  
Diagnosis Therapy ◽  
Malignant Germ Cell Tumors

Gynecological cancers pose an important public health issue, with a high incidence among women of all ages. Gynecological cancers such as malignant germ-cell tumors, sex-cord-stromal tumors, uterine sarcomas and carcinosarcomas, gestational trophoblastic neoplasia, vulvar carcinoma and melanoma of the female genital tract, are defined as rare with an annual incidence of <6 per 100,000 women. Rare gynecological cancers (RGCs) are associated with poor prognosis, and given the low incidence of each entity, there is the risk of delayed diagnosis due to clinical inexperience and limited therapeutic options. There has been a growing interest in the field of microRNAs (miRNAs), a class of small non-coding RNAs of ∼22 nucleotides in length, because of their potential to regulate diverse biological processes. miRNAs usually induce mRNA degradation and translational repression by interacting with the 3′ untranslated region (3′-UTR) of target mRNAs, as well as other regions and gene promoters, as well as activating translation or regulating transcription under certain conditions. Recent research has revealed the enormous promise of miRNAs for improving the diagnosis, therapy and prognosis of all major gynecological cancers. However, to date, only a few studies have been performed on RGCs. In this review, we summarize the data currently available regarding RGCs.

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