The estimation of sodium chloride content by quantitative determination of sodium or chloride ion in cooked foodstaffs.

Purpose of the study:The purpose of this present study was determine the concentration of chloride ion in water sample which collected different site and season of river Ganga.Chloride ions in the environment can come from sodium chloride or from other chloride salts such as potassium chloride, calcium chloride and magnesium chloride. Methodology:Water sample was collected from different site(Bithor ghat, Siddnath ghat and Dhoni ghat) and different season(Pre monsoon, Monsoon and post monsoon) of river Ganga from Kanpur in 2016-2018 year. Mohr method (Argentometric method) was a very simple and highly selective method for the determination of chloride ion (Cl-) using silver nitrate as the titrant. Main Findings: In both the years 2016 till 2018, chloride concentration was within the limit at testing sites. Applications of this study:To create awareness among the people to maintain the Ganga river water at its highest quality and purity levels. Originality: This project was done in the D G P G College C S J M University, Kanpur India.

Download Full-text

The enzymatic method for the quantitative determination of benzalkonium chloride in the antiseptic solution “CUTASEPT® F”

Žurnal organìčnoï ta farmacevtičnoï hìmìï ◽

10.24959/ophcj.21.244359 ◽

2021 ◽

Vol 19 (4(76)) ◽

pp. 33-39

Author(s):

Olena V. Koval’ska ◽

Mykola Ye. Blazheyevskіy

Keyword(s):

Enzymatic Hydrolysis ◽

Quantitative Determination ◽

Peracetic Acid ◽

Benzalkonium Chloride ◽

Chloride Content ◽

Inhibitory Effect ◽

Enzymatic Method ◽

Limit Of Quantitation ◽

Hydrolysis Of

Aim. To develop an alternative method for the quantitative determination of the benzalkonium chloride content as an active pharmaceutical ingredient in the disinfectant solution “CUTASEPT® F”.Materials and methods. The method is based on the ability of benzalkonium chloride to inhibit the enzymatic hydrolysis of acetylcholine by acetylcholinesterase. The reaction rate is assessed by the non-hydrolyzed acetylcholine residue, which is determined by the amount of peracetic acid produced during the interaction with the excess of the hydrogen peroxide solution. The indicator reaction is the interaction of p-phenetidine with peracetic acid that leads to the formation of 4,4’-azoxyphenetole with λmax = 358 nm (log10 ε = 4.2).Results and discussion. As a result of the research conducted the linear dependence of the degree of inhibition of the enzymatic hydrolysis of acetylcholine (U, %) on the concentration of benzalkonium chloride was determined in the concentration range of (0.5 – 7.0) × 10–6 mol L-1 with the correlation coefficient of 0.999. The limit of quantitation was 1.9 × 10–6 mol L-1.Conclusions. As a result of the research conducted the kinetic enzymatic method for the quantitative determination of benzalkonium chloride has been developed by its inhibitory effect in the biochemical reaction of acetylcholine hydrolysis. This method is fast, cheap and easy to perform, does not require expensive equipment, and available for use in the field.

Download Full-text

Quantitative determination of Levomepromazine in pharmaceuticals by spectrophotometric method as its sulfoxide

French-Ukrainian Journal of Chemistry ◽

10.17721/fujcv8i1p117-124 ◽

2020 ◽

Vol 8 (1) ◽

pp. 117-124

Author(s):

Olena Mozgova ◽

Mykola Blazheyevskiy

Keyword(s):

Sodium Chloride ◽

Citric Acid ◽

Quantitative Determination ◽

Spectrophotometric Determination ◽

Spectrophotometric Method ◽

Present Method ◽

Limit Of Quantification ◽

Derivatizing Agent ◽

Sensitive Method

The oxidative derivatization method using Diperoxyazelaic acid for the indirect spectrophotometric determination of Levomepromazine hydrochloride is presented. Diperoxyazelaic acid is introduced as a derivatizing agent for Levomepromazine, yielding the sulfoxides. This reaction product was successfully used for the spectrophotometric determination of the Levomepromazine hydrochloride. The UV spectroscopic detection of the sulfoxide proved to be a more robust and sensitive method. The elaborated method allowed the determination of Levomepromazine hydrochloride in the concentration range of 3-150 µg/mL. The limit of quantification, LOQ (10S) is 2.85 µg/mL. A new spectrophotometric technique was developed and the possibility of quantitative determination of Levomepromazine in Tisercin Solution for Injection 25mg/mL was demonstrated. The present method is precise, accurate and other excipients: anhydrous citric acid, monothioglycerol, sodium chloride did not interfere. RSD = 1.24 % (δ = –0.02 %).

Download Full-text

Development and validation of a simple spectrophotometric method for quantification of chloride in polymeric materials

Science and Technology Development Journal ◽

10.32508/stdj.v18i2.1177 ◽

2015 ◽

Vol 18 (2) ◽

pp. 152-158

Author(s):

Chau Minh Huynh ◽

Nguyen Thao Nguyen ◽

Vu Dinh Thien Vo ◽

Mai Anh Nguyen

Keyword(s):

Benzyl Chloride ◽

Limit Of Detection ◽

Base Material ◽

Polymeric Materials ◽

Chloride Ion ◽

Chloride Content ◽

Spectrophotometric Analysis ◽

Linear Calibration ◽

Development And Validation

A simple analytical method was developed for determination of chloride content in polymeric materials. The procedure comprises of two steps, the dissolution of the polymer by alkaline fusion followed by indirect spectrophotometric analysis of the chloride based on the absorption at 460 nm of Fe(SCN)2+, a product of the reaction between chloride ion and a mixture of mercury (II) thiocyante and ferric ion. A non-linear calibration curve was constructed from 0.5 to 20 ppm with R2 = 0.9991; the limit of detection and quantitation were of 0.325 and 1.083 ppm, respectively. The recovery of the whole procedure was higher than 92.9 % with a RSD ~ 2.4 %. The developed procedure was applied to animated poly(divinylbenzene-co-vinyl benzyl chloride) in order to investigate the extent of amination of the base material.

Download Full-text

Quantitative Determination of a Small Amount of Mercury in the Presence of Large Amount of Chloride Ion and An Equilibrium of "Enolized" Dithizone-Mercury (II)Compoumd

BUNSEKI KAGAKU ◽

10.2116/bunsekikagaku.5.689 ◽

1956 ◽

Vol 5 (12) ◽

pp. 689-695 ◽

Cited By ~ 10

Author(s):

Takio KATO ◽

Shinsuke TAKE ◽

Akio OKAGAMI

Keyword(s):

Quantitative Determination ◽

Chloride Ion

Download Full-text

COVID-19 and PM2.5 Sodium Chloride content

10.21203/rs.3.rs-31884/v1 ◽

2020 ◽

Cited By ~ 1

Author(s):

Yves Muscat Baron

Keyword(s):

Sodium Chloride ◽

Salt Content ◽

Chloride Ion ◽

Chloride Content ◽

Infection Rates ◽

Coastal Cities ◽

Increased Risk ◽

Low Salt ◽

Airborne Pollutant ◽

Maximum Minimum

Abstract INTRODUCTION: Following national lockdown instituting physical distancing, COVID-19 infection and mortality decreased in most countries. Simultaneously due to diminished economic and human activity, the atmospheric levels of PM2.5, an important airborne pollutant, decreased significantly. COVID-19 has been found adherent to PM2.5. PM2.5 has various components including sodium chloride which determines the amount of PM2.5 salt-derived water content. Atmospheric salt content in part determines the sodium chloride content and the consequential hygroscopicity of PM2.5. COVID-19 possesses a C-terminal protein which is hydrophobic.METHOD: The sodium chloride content of the PM2.5 species was assessed in two groups of cities. Cities were chosen as opposed to countries, because substantial regional differences in infection rates were noted between inland and coastal cities. These cities were differentiated by the rate COVID-19 infection and consequent mortality. Atmospheric salt content was obtained from research that assessed chloride ion wet deposition, a proxy for airborne salinity. The salt content of the relevant PM2.5 species was obtained from publications from the various cities assessed.RESULTS: Cities with high COVID-19 infection rates had PM2.5 species with significantly lower salt content than the cities with low Covid-17 infection. The PM2.5 salt content in the cities with elevated COVID-19 rates was 0.196µg/m3 SD 0.05µg/m3, while cities with low COVID-19 rates had a PM2.5 salt content of 0.81µg/m3 SD 0.32µg/m3 (p<0.0001).There was a significant correlation between atmospheric salinity and the salt content of PM2.5. PM2.5 salt content correlated with minimum atmospheric salinity (R=0.53, p < 0.01) and maximum atmospheric salinity (R=0.64, p <0.002). There appears to be an inverse relationship between COVID-19 infection and atmospheric salt content levels. Cities that were spared high COVID-19 infection rates, have higher maximum/minimum atmospheric salinity content levels (216-1080 mgCl/m2/day) compared to sodium chloride levels noted in cities with high COVID-19 rates of infection (40-125. mgCl/m2/day) (p<0.005).CONCLUSION: PM2.5 with low salt content, in the presence of low ambient salinity may be linked to an increased risk of COVID-19 infection in the population.

Download Full-text