Gait Characteristics in Youth With Transverse Myelitis

2021 ◽  
Vol 27 (3) ◽  
pp. 38-48
Author(s):  
Miriam Hwang ◽  
Ann Flanagan ◽  
Adam Graf ◽  
Karen M. Kruger ◽  
Nancy Scullion ◽  
...  

Background: Transverse myelitis (TM) in childhood is a rare disorder characterized by the presence of spinal cord inflammation. Gait difficulty in children with TM is common; however, there is a paucity of literature regarding quantitative assessment of gait in children and adolescents with TM. Objectives: To characterize gait patterns in a cohort of ambulatory children with TM and age-matched, typically developing peers in order to better understand the functional mobility of patients diagnosed with childhood TM. Methods: This was a retrospective study of 26 ambulatory pediatric patients with a confirmed diagnosis of TM who had undergone three-dimensional, instrumented gait analysis (3D-IGA) at 3 years of age or older. A group of 38 typically developing children served as a control group. Results: Gait in children with TM was characterized by moderate kinematic deviations as measured by the Gait Deviation Index (GDI) and a crouched gait pattern (p < .001), increased anterior pelvic tilt (p < .001), decreased motion at the knees (p < .001), and a wider base of support (foot progression angle, p < .001). The TM group had a slower walking speed (p < .001), shorter strides (p < .001), and an increased stance phase compared to controls. Conclusion: Our study results showed moderate kinematic deviations quantified by the GDI. Overall, the gait pattern in the TM population tested had greater hip and knee flexion with wider foot progression angle. Identification of gait characteristics in children with TM is the first step in predicting changes in gait pattern as they mature over time, which may ultimately allow for targeted intervention to maintain their ambulatory function.

Author(s):  
Heydar Sadeghi ◽  
Hesam Fazlali ◽  
Saba Sadeghi ◽  
Seyedmojtaba Seyedmojtaba Ojaghi

Background: In athletes with anterior cruciate ligament (ACL) deficiencies could assess functional capabilities with different instruments such as use of a camera in vivo situation. However, these methods have suffered from a large number of limitations such as inability to be repeatable and complexity in technique. Objective: The main purpose of this study was to compare gait pattern of the athletes with ACL injury and able-bodied subjects using an accelerometer. Method: A three-dimensional accelerometer was placed over the tibia tuberosity of 20 healthy and 20 individuals with ACL-deficiencies (ACLD). After walking on the treadmill, the principal components of the acceleration data were calculated using MATLAB software. Results: In this study, Principle Component analysis was used for statistical analysis. The results indicated that subjects with ACL deficiency have different gait pattern compared to the control group. The major differences between stride trajectories of the two groups were at the end of mid-swing and the beginning of terminal swing phases in vertical axis. ACL deficient subjects exhibited different gait patterns during mid and terminal stance phases in anterior- posterior axis compared with normal controls. Conclusions: The difference in gait between subjects with ACL deficiency and healthy subjects are depends on variation in the amount of knee flexion and tibia rotation that could be altered to motor recruitment.


2014 ◽  
Vol 30 (2) ◽  
pp. 221-230 ◽  
Author(s):  
Tom Melai ◽  
Nicolaas C. Schaper ◽  
T. Herman IJzerman ◽  
Paul J.B. Willems ◽  
Ton L.H. de Lange ◽  
...  

Increased forefoot loading in diabetic polyneuropathy plays an important role in the development of plantar foot ulcers and can originate from alterations in muscle strength, joint moments and gait pattern. The current study evaluated whether strength training can improve lower extremity joint moments and spatiotemporal gait characteristics in patients with diabetic polyneuropathy. An intervention group receiving strength training during 24 weeks and a control group receiving no intervention. Measurements were performed in both groups at t = 0, t = 12, t = 24 and t = 52 weeks at an individually preferred and standardized imposed gait velocity. The strength training did not affect the maximal amplitude of hip, knee and ankle joint moments, but did result in an increase in stance phase duration, stride time and stride length of approximately 5%, during the imposed gait velocity. In addition, both groups increased their preferred gait velocity over one year. Future longitudinal studies should further explore the possible effects of strength training on spatiotemporal gait characteristics. The current study provides valuable information on changes in gait velocities and the progressive lower extremity problems in patients with polyneuropathy.


2008 ◽  
Vol 1 (1) ◽  
Author(s):  
Kenneth J. Waldron ◽  
J. Estremera ◽  
Paul J. Csonka ◽  
S. P. N. Singh

This paper focuses on modeling the gait characteristics of a quadrupedal gallop. There have been a number of studies of the mechanics of the stance phase in which a foot is in contact with the ground. We seek to put these studies in the context of the stride, or overall motion cycle. The model used is theoretical, and is kept simple in the interest of transparency. It is compared to empirical data from observations of animals, and to data from experiments with robots such as our KOLT machine, and results from sophisticated simulation studies. Modeling of the energy loss inherent in the interaction between the system and the environment plays a key role in the study. Results include the discovery of a hidden symmetry in the gait pattern, usually regarded as being completely asymmetrical. Another result demonstrates that the velocities with which the two front feet impact and leave the ground are different, and similarly for the rear feet. The velocities of the foot pairs mirror each other. This is consistent with empirical observation, but is at variance with the assumption used almost universally when modeling stance. A further result elicits the importance of the pitch moment of inertia and other effects that make the mammalian architecture, in which the center of mass is closer to the shoulders than to the hips, beneficial..


2021 ◽  
Author(s):  
Peishun CHEN ◽  
Haiwang ZHOU ◽  
Taotao LI ◽  
Hongli GUANG ◽  
Yu MIN ◽  
...  

Abstract Background and PurposeTo analyze the changes of gait characteristics in stroke patient with foot drop after treating by foot drop stimulator combined with moving treadmill, and provide a basis for the improvement of foot drop gait after stroke.Methods Sixty patients with stroke and hemiplegia with foot drop were randomly divided into the experimental group and the control group. Both groups received basic rehabilitation training. On this basis, the experimental group received foot drop stimulator combined with moving treadmil. The control group received foot drop stimulator training. The treatment time of the two groups was 30 minutes/time, 5 times a week, for 3 consecutive weeks. Gait Watch three-dimensional gait analysis system was used to record the angle of hip flexion, knee flexion and ankle flexion before and after treatment. Results After treatment, the angles of hip flexion, knee flexion, and ankle flexion of the two groups of patients changed, but the above changes in the experimental group were better than those in the control group, The difference is statistically significant (p<0.05). ConclusionsThe foot drop stimulator combined with moving treadmill can significantly improve the foot gait after stroke, and promote the normalization of hip flexion and knee flexion.


2019 ◽  
Author(s):  
Julie Soulard ◽  
Jacques Vaillant ◽  
Clara-Thémis Agier ◽  
Nicolas Vuillerme

BACKGROUND Ankylosing spondylitis (AS) is a chronic rheumatic disease which affects the axial skeleton and sacro-iliac joints. By impacting spinal mobility and physical functions, AS could also potentially impair gait. However, while published data are rather sparse, it appears that discrepancies exist regarding AS consequences on gait characteristics, tasks and analysis techniques used to assess gait ability of patients with AS. OBJECTIVE The review questions are twofold: (1) What are the consequences of AS on gait? and (2) How is gait assessed in patients with AS? METHODS Databases were systematically searched to identify studies satisfying the search criteria, using the synonyms of ankylosing spondylitis and gait. Two reviewers extracted from the articles study characteristics, sample descriptions, methods and main results in relation to gait. RESULTS 168 titles were extracted from databases and 17 studies were included in the review. 13 studies (76%) used clinical gait measurements, and 4 (23%) used laboratory gait measurements. Only 6 involved a healthy control group. Gait pattern of patients with AS was more cautious, associated to a decreased pelvic tilt and lower limbs angles in the sagittal plane. Studies used diverse protocols, instructions and parameters when assessing gait in AS patients. CONCLUSIONS Only few studies have assessed gait characteristics in patients with AS. Published data evidence that no consensus exists regarding gait analysis methods for patients with AS. However, published studies are encouraging as they provide us the opportunity to propose guidelines to improve the design and methodology for future studies on gait and AS. CLINICALTRIAL PROSPERO: CRD42018102540 and JMIR Res Protoc doi:10.2196/12470


2020 ◽  
Vol 2 (2) ◽  
pp. 112-120
Author(s):  
Nursari Abdul Syukur ◽  
Susi Purwanti

Many mothers who give birth to Sectio Caesarea (SC) do not Initiate Early Breastfeeding (IMD), which fails exclusive breastfeeding. This study aimed to determine the effect of IMD management in postpartum SC mothers on nutritional status, speed of milk production, and quality of breast milk protein. Method: quantitative research with quasi approach experiment. The research design used was a pre-post-test control non-equivalent control group. A sampling of this study used the Consecutive method sampling with a sample of 20 mothers who gave birth by cesarean section (SC). Hypothesis testing uses the independent t-test and the Mann-Whitney test. The study results showed an influence on the management of IMD in postpartum SC mothers on the speed of ASI production (p-value=0.004) and nutritional status (p-value=0.028). There was no effect of IMD management on postpartum SC mothers on the quality of breast milk protein (p-value = 0.543). This study recommends that the hospital implement an IMD promotion program before the abdominal wall is closed as a form of intervention to increase milk production and maternal nutritional status


2016 ◽  
pp. 191-108
Author(s):  
A.A. Sukhanova ◽  
◽  
Yu.M. Melnik ◽  
O.O. Karlova ◽  
◽  
...  

The aim of the study: to study the efficacy and safety of use Mastofemin in the treatment of various forms of mastitis in women of reproductive age. Materials and methods. The study included 62 women of reproductive age (mean age of 33.5±2.3 years) who were screened in the Kiev city center reproductive and perinatal medicine. Women were divided into 2 groups. The first (main) group consisted of 32 patients who received the proposed treatment using herbal remedies Mastofemin 1 capsule 2 times per day for 3 months; 30 patients of the second (control) group were under observation and received no treatment. These groups were representative and homogeneous on age, clinical symptoms and sonographic characteristics. The clinical method included evaluation of complaints of patients, anamnesis, presence of concomitant gynecologic pathology, inspection, palpation of the lymph nodes and the breast and obtaining a discharge from the nipples to conduct cytological examination, which allowed excluding from the study women with suspected malignancy of the process. All the patients were performed ultrasound examination of the breast. The review was supplemented with vaginal gynecological examination and ultrasound examination of small pelvis organs to assess the condition of the uterus and its appendages, the diagnosis of gynecological diseases. Results. Summarizing obtained in this study results one should stress the positive long-term effect of applying Mastofemin for the treatment of proliferative changes of the breast in women of reproductive age. This is manifested by a decrease in the intensity of clinical signs of mastitis, consistent with the results of sonographic control. Established positive dynamics in the treatment of cystic mastitis, dectective and when combined cystic mastopathy with dectective. In the control group of patients for a given observation period (6 months) no significant changes in clinical signs of mastitis and sonographic characteristics. Regression of disease has not occurred in any of the patients, in 2 patients increased sensitivity of the breast after 6 months moved to the soreness. Sonographic characteristics of mastitis during the observation period did not change. Thus, the use of Mastofemin aimed at pathogenetic treatment of mastitis and prevention of breast cancer. Conclusion. Application of Mastofemin during the treatment of mastitis in women of reproductive age significantly improves the clinical condition of patients; reduce the subjective and objective symptoms of the disease. The positive effect of the treatment with Mastofemin proved in the case of the treatment of sonographic following forms of mastitis: cystic mastopathy, cystic mastopathy with dectectasy. Mastofemin may be the drug of choice for complex conservative monotherapy in women of reproductive age with proliferative changes in the breast, and can also be used as part of complex treatment in patients with diffuse changes of the breast when combined with hyperplastic processes of the myometrium and endometrium. Keywords: mastopathy, breast gland, herbal medicine, herbal remedies, Mastofemin.


2018 ◽  
Vol 9 (01) ◽  
Author(s):  
Praful Prabhuappa Kapse ◽  
Manisha Kiran

Caring for the persons with first episode psychosis is challenging and demanding. It may lead to the increased burden, expressed emotions among the caregivers. The numerous studies have shown that high burden and negative expressed emotions among caregivers can lead to early relapse in the patients with first episode psychosis. To evaluate the effects of the brief psychoeducation on the caregivers burden and expressed emotions. A quasi experimental - before and after with control group research design was adopted for the study. A total of 60 caregivers have participated in the study, of which 30 caregivers in experimental group and 30 caregivers in the control group. Family Burden Interview Schedule (Pai and Kapoor, 1981) and Attitude Questionnaire (Sethi et al., 1981) was used to assess caregiver's burden and expressed emotions. At end of the psychoeducation intervention, burden among caregivers and negative expressed emotions of the caregivers have significantly reduced. The positive expressed emotions have been increased. Study results demonstrates the importance of psychoeducation intervention in reducing the burden and negative expressed emotions.


2018 ◽  
Vol 40 (4) ◽  
pp. 323-327 ◽  
Author(s):  
F Tas ◽  
S Karabulut ◽  
K Erturk ◽  
D Duranyildiz

Aim: Caveolin-1 plays a significant role in the pathogenesis of various carcinomas and its expression affects the survival of cancer patients. However, the molecular function of caveolin-1 and its possible clinical importance has remained uncertain in gastric cancer. No clinical trial has examined serum caveolin-1 levels in gastric cancer patients so far, instead all available results were provided from studies conducted on tissue samples. In the current study, we analyzed the soluble serum caveolin-1 levels in gastric cancer patients, and specified its associations with the clinical factors and prognosis. Material and Methods: Sixty-three patients with pathologically confirmed gastric cancer were enrolled into the trial. Serum caveolin-1 concentrations were detected by ELISA method. Thirty healthy subjects were also included in the study. Results: The median age of patients was 62 years, ranging from 28 to 82 years. The serum caveolin-1 levels in gastric cancer patients were significantly higher than those in control group (p < 0.001). The common clinical parameters including patient age, sex, lesion localization, histopathology, histological grade, disease stage, and various serum tumor markers (e.g. LDH, CEA, and CA 19.9) were not found to be associated with serum caveolin-1 levels (p > 0.05). Similarly, no correlation existed between serum caveolin-1 concentration and chemotherapy responsiveness (p = 0.93). Furthermore, serum caveolin-1 level was not found to have a prognostic role (p = 0.16). Conclusion: Even though it is neither predictive nor prognostic, serum caveolin-1 level may be a valuable diagnostic indicator in patients with gastric cancer. Key


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