scholarly journals Gait Characteristics In patients With Ankylosing Spondylitis – a Systematic Review (Preprint)

2019 ◽  
Author(s):  
Julie Soulard ◽  
Jacques Vaillant ◽  
Clara-Thémis Agier ◽  
Nicolas Vuillerme
Keyword(s):  
Ankylosing Spondylitis ◽  
Sagittal Plane ◽  
Axial Skeleton ◽  
Gait Pattern ◽  
Lower Limbs ◽  
Spinal Mobility ◽  
Control Group ◽  
Published Data ◽  
Gait Characteristics ◽  
Study Characteristics

BACKGROUND Ankylosing spondylitis (AS) is a chronic rheumatic disease which affects the axial skeleton and sacro-iliac joints. By impacting spinal mobility and physical functions, AS could also potentially impair gait. However, while published data are rather sparse, it appears that discrepancies exist regarding AS consequences on gait characteristics, tasks and analysis techniques used to assess gait ability of patients with AS. OBJECTIVE The review questions are twofold: (1) What are the consequences of AS on gait? and (2) How is gait assessed in patients with AS? METHODS Databases were systematically searched to identify studies satisfying the search criteria, using the synonyms of ankylosing spondylitis and gait. Two reviewers extracted from the articles study characteristics, sample descriptions, methods and main results in relation to gait. RESULTS 168 titles were extracted from databases and 17 studies were included in the review. 13 studies (76%) used clinical gait measurements, and 4 (23%) used laboratory gait measurements. Only 6 involved a healthy control group. Gait pattern of patients with AS was more cautious, associated to a decreased pelvic tilt and lower limbs angles in the sagittal plane. Studies used diverse protocols, instructions and parameters when assessing gait in AS patients. CONCLUSIONS Only few studies have assessed gait characteristics in patients with AS. Published data evidence that no consensus exists regarding gait analysis methods for patients with AS. However, published studies are encouraging as they provide us the opportunity to propose guidelines to improve the design and methodology for future studies on gait and AS. CLINICALTRIAL PROSPERO: CRD42018102540 and JMIR Res Protoc doi:10.2196/12470

Clinical Correlates of Urolithiasis in Ankylosing Spondylitis

2011 ◽  
Vol 38 (9) ◽  
pp. 1953-1956 ◽  
Author(s):  
NAI LEE LUI ◽  
ADELE CARTY ◽  
NIGIL HAROON ◽  
HUA SHEN ◽  
RICHARD J. COOK ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Ankylosing Spondylitis ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Functional Disability ◽  
Spinal Mobility ◽  
Joint Involvement ◽  
Control Group ◽  
Significant Difference ◽  
History Of

Objective.To determine the association between urolithiasis and syndesmophyte formation and the effect of urolithiasis on ankylosing spondylitis (AS) disease activity.Methods.In a longitudinal cohort of 504 patients with AS, we conducted an analysis of all patients with AS who have a history of urolithiasis. All patients met the modified New York criteria for AS. Demographics, clinical characteristics, extraarticular features, and comorbidities are systematically recorded in the database. We compared disease activity, functional indices, medical therapy and radiographic damage between AS patients with (Uro+) and without urolithiasis (Uro–) using the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS).Results.Thirty-eight patients with AS (7.5%) had a history of urolithiasis in our cohort. Seventy-six patients with AS who did not have urolithiasis, matched for age, sex, and ethnicity, were selected as controls. Patients who were Uro+ were more likely to have more functional disability, based on the Bath AS Functional Index (BASFI; mean 5.3 vs 3.6 in control group, p = 0.003). Trends were noted in the Uro+ group toward higher Bath AS Disease Activity Index (BASDAI; mean 4.9 vs 4.0, p = 0.09), more peripheral joint involvement (p = 0.075), and higher frequency of biologic therapy (p = 0.09). No significant difference was detected in mSASSS or the Bath AS Metrology Index (BASMI). Significant association with diabetes mellitus (DM; p = 0.016) and Crohn’s disease (p = 0.006) was noted in the Uro+ group.Conclusion.Although there is no acceleration of syndesmophyte formation or spinal mobility restriction, more functional disability was detected in the urolithiasis group. The higher risk with concomitant DM or Crohn’s disease should alert clinicians to these comorbidities in Uro+ patients with AS.

MODERN VIEW ON THE PROBLEM OF OSTEOPOROSIS IN ANKYLOSING SPONDYLITIS

2020 ◽  
Vol 5 (4) ◽  
pp. 19-28
Author(s):  
Tat'yana Raskina ◽  
O. Malyshenko ◽  
M. Pirigova ◽  
M. Letaeva ◽  
Yu. Averkieva
Keyword(s):  
Ankylosing Spondylitis ◽  
Early Detection ◽  
Axial Skeleton ◽  
Diagnostic Techniques ◽  
Control Group ◽  
Hla B27 ◽  
Functional Disorders ◽  
Healthy Men ◽  
X Ray ◽  
Reliable Diagnosis

The study included 72 men with a reliable diagnosis of AS, mean age – 43,2±9,1 years. X-ray examination of the axial skeleton and peripheral joints was carried out, HLA-B27 was determined. Disease activity was assessed using the index ВАSDАI, functional disorders with the help of the BASFI index. BMD was determined by two-energy x-ray absorptiometry. The control group consisted of 74 healthy men, mean age – 46,7±0,9 years. Given the chronic nature and asymptomatic course of osteoporosis, the task of doctors working with this group of patients is an active search for osteoporosis using all available diagnostic techniques for the early detection of this condition and subsequent correction of the drug treatment.

scholarly journals Surgical management of global sagittal deformity in ankylosing spondylitis

2008 ◽  
Vol 24 (1) ◽  
pp. E8 ◽  
Author(s):  
Charles A. Sansur ◽  
Kai-Ming G. Fu ◽  
Rod J. Oskouian ◽  
Jay Jagannathan ◽  
Charles Kuntz ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Preoperative Planning ◽  
Sagittal Plane ◽  
Axial Skeleton ◽  
Pedicle Subtraction Osteotomy ◽  
Review Article ◽  
Cervicothoracic Junction ◽  
Plane Deformity ◽  
Sagittal Deformity ◽  
Review Current

✓ Ankylosing spondylitis (AS) is an inflammatory rheumatic disease whose primary effect is on the axial skeleton, causing sagittal-plane deformity at both the thoracolumbar and cervicothoracic junctions. In the present review article the authors discuss current concepts in the preoperative planning of patients with AS. The authors also review current techniques used to treat sagittal-plane deformity, focusing on pedicle subtraction osteotomy at the thoracolumbar junction, as well as cervical extension osteotomy at the cervicothoracic junction.

scholarly journals Strength Training Affects Lower Extremity Gait Kinematics, Not Kinetics, in People With Diabetic Polyneuropathy

2014 ◽  
Vol 30 (2) ◽  
pp. 221-230 ◽  
Author(s):  
Tom Melai ◽  
Nicolaas C. Schaper ◽  
T. Herman IJzerman ◽  
Paul J.B. Willems ◽  
Ton L.H. de Lange ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Strength Training ◽  
Intervention Group ◽  
Diabetic Polyneuropathy ◽  
Gait Pattern ◽  
Gait Velocity ◽  
Control Group ◽  
Joint Moments ◽  
Phase Duration ◽  
Gait Characteristics

Increased forefoot loading in diabetic polyneuropathy plays an important role in the development of plantar foot ulcers and can originate from alterations in muscle strength, joint moments and gait pattern. The current study evaluated whether strength training can improve lower extremity joint moments and spatiotemporal gait characteristics in patients with diabetic polyneuropathy. An intervention group receiving strength training during 24 weeks and a control group receiving no intervention. Measurements were performed in both groups at t = 0, t = 12, t = 24 and t = 52 weeks at an individually preferred and standardized imposed gait velocity. The strength training did not affect the maximal amplitude of hip, knee and ankle joint moments, but did result in an increase in stance phase duration, stride time and stride length of approximately 5%, during the imposed gait velocity. In addition, both groups increased their preferred gait velocity over one year. Future longitudinal studies should further explore the possible effects of strength training on spatiotemporal gait characteristics. The current study provides valuable information on changes in gait velocities and the progressive lower extremity problems in patients with polyneuropathy.

THREE-DIMENSIONAL GAIT ANALYSIS AS A POTENTIAL AND QUANTIFIABLE MEASUREMENT IN THE CLINICAL EVALUATION OF ANKYLOSING SPONDYLITIS

2016 ◽  
Vol 16 (02) ◽  
pp. 1650001
Author(s):  
M. M. XUEMEI PIAO ◽  
M. D. LUAN XUE ◽  
M. D. SHUYUN JIANG ◽  
M. D. JIANDONG HU ◽  
M. M. GUOLING LI
Keyword(s):  
Ankylosing Spondylitis ◽  
Gait Analysis ◽  
Stride Length ◽  
Three Dimensional ◽  
Step Length ◽  
Lower Limbs ◽  
Spinal Mobility ◽  
Lateral Bending ◽  
Clinical Value ◽  
Spinal Rotation

The present study aimed to investigate the potential clinical value of three-dimensional gait analysis (3D-GA) system in evaluating ankylosing spondylitis (AS). Thirty-one patients with AS from September 2010 to August 2011, with 32 involved and 30 uninvolved lower limbs, were enrolled. Data of spatio-temporal parameters (step and stride length, velocity and cadence), time parameters (stance, single stance, double stance and swing phases) and kinematics parameters associated with spinal mobility (spinal lateral bending, spinal forward bending and spinal rotation) were analyzed by 3D-GA system, as well as curative effects of biologic therapy. Compared with normal values, AS patients showed decreased step and stride length ([Formula: see text]), increased cadence, longer swing and single stance phases ([Formula: see text]) and shorter stance and double stance phases ([Formula: see text]) in uninvolved lower limbs. In AS patients, reduced step length, stride length, velocity and cadence, shorter swing and single stance phases, longer stance and double stance phases ([Formula: see text]), increased lateral bending angle and decreased spinal rotation ([Formula: see text]) were detected by 3D-GA in involved lower limbs compared with uninvolved ones. In the 16 patients with decreased levels of ESR and CRP and improved ASAS scores after biology therapy, increased step length, stride length, velocity and cadence of the involved lower limbs were detected by 3D-GA ([Formula: see text]), as well as improved spinal mobility ([Formula: see text]). Hence, we concluded that 3D-GA has great potential value of clinical application for assessing and monitoring AS.

Clinical Features of Late-onset Ankylosing Spondylitis: Comparison with Early-onset Disease

2012 ◽  
Vol 39 (5) ◽  
pp. 1008-1012 ◽  
Author(s):  
CARLOS MONTILLA ◽  
JAVIER DEL PINO-MONTES ◽  
EDUARDO COLLANTES-ESTEVEZ ◽  
PILAR FONT ◽  
PEDRO ZARCO ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Clinical Features ◽  
Early Onset ◽  
Late Onset ◽  
Age At Onset ◽  
Young Patients ◽  
Lower Limbs ◽  
Joint Disease ◽  
Control Group ◽  
Onset Group

Objective.Ankylosing spondylitis (AS) is generally observed in young patients but can occur later in life or in persons ≥ 50 years of age. Our objective was to characterize the clinical features of late-onset AS in a large multicenter national cohort.Methods.We studied late-onset AS in the National Registry of Spondyloarthritis of the Spanish Society of Rheumatology (REGISPONSER database) cohort (n = 1257), of whom 3.5% had onset at age ≥ 50 years versus a control group with onset at < 50 years.Results.There were no differences between late-onset and early-onset AS according to sex and family history of spondyloarthropathies. Patients in the late-onset group more often showed involvement of the cervical spine (22.7% vs 9.7%; p = 0.03) and arthritis of the upper (13.6% vs 3.0%; p = 0.002) and lower limbs (27.3% vs 15.2%; p = 0.03) as first manifestations than did patients in the early-onset group. A higher percentage of mixed forms (axial and peripheral joint disease) during the course of the disease was also recorded in the late-onset group (50% vs 24%; p = 0.0001).Conclusion.Our study suggests that age at onset of AS affects the patients’ presenting clinical form. Arthritis of the upper limbs requires a differential diagnosis with other conditions frequent in patients over 50 years of age, such as rheumatoid arthritis or crystal-induced arthropathy.

The Effect of Impaired Plantar Sensation on Gait in People with Multiple Sclerosis

2009 ◽  
Vol 11 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Kevin J. Kelleher ◽  
William D. Spence ◽  
Stephan E. Solomonidis ◽  
Dimitrios P. Apatsidis
Keyword(s):  
Multiple Sclerosis ◽  
Sensory Feedback ◽  
Sagittal Plane ◽  
Gait Pattern ◽  
Knee Extensors ◽  
Control Group ◽  
Plantar Flexors ◽  
Gait Patterns ◽  
Ambulatory Ability ◽  
Reaction Forces

People with multiple sclerosis (MS) often experience debilitating motor and sensory dysfunction. The aim of this study was to determine whether impaired plantar sensation affects gait patterns in MS patients, as it does in other patient populations such as those with diabetes mellitus. Sixteen patients with MS were recruited and divided into two groups according to their ambulatory ability. Ten healthy subjects made up a control group. Plantar sensation thresholds were measured and kinematic and kinetic gait data were collected for both MS groups and the control group. The MS patients had less sensation than the control group at all plantar sites tested. Gait speed and hip, knee, and ankle joint sagittal plane excursion were significantly lower in both MS groups than in the control group. Braking and push-off ground reaction forces were significantly lower in both MS groups than in the control group, and patients were found to carry the limb through the swing phase using the hip flexors and knee extensors owing to insufficient push-off from the ankle plantar flexors. The reduced plantar sensation in MS patients is likely to be a significant factor in this “cautious” gait pattern. Improving sensory feedback from the sole of the foot through the prescription of specialized footwear and orthoses may facilitate gait in people with MS.

scholarly journals Dynamic Stability Assessment of the Lower Limbs of Karate Kyokushin Master Class Athletes

2014 ◽  
Vol 2 (11_suppl3) ◽  
pp. 2325967114S0021
Author(s):  
Tomasz Jurkiewicz ◽  
Daria Mejnartowicz ◽  
Marcin Plenzler ◽  
Anna Mierzwińska ◽  
Marcin Popieluch ◽  
...  
Keyword(s):  
Lower Limb ◽  
Sagittal Plane ◽  
Lower Limbs ◽  
Control Group ◽  
Training Experience ◽  
Training History ◽  
Left Limb ◽  
Significant Difference ◽  
Overall Stability ◽  
Karate Athletes

Objectives: The aim of the study was to determine the level of stability of the lower limbs in dynamic conditions in Karate Kyokushin master class athletes. We compared the results of the karate athletes with the control group. In the analysis, both the dominant (kicking) limb and non-dominant (supporting) one were taken into account. Methods: The study involved 22 Karate Kyokushin master class athletes (13 men and 9 women aged 26.5 ± 3.9). This group consisted mainly of European Championships medalists in various weight categories. Their average training history was 14.6 ± 5.1 years. The control group consisted of 18 healthy, active volunteers (14 men and 4 women aged 21.4 ± 1.2). The measurements of dynamic stabilography were made with the Biodex Balance System (BBS) device. The dispersion of sway in the A/P (anterior/posterior) plane, M/L (medial/lateral) plane and overall stability indicator (OSI) were analyzed. The measurements were made with one leg position on the lower right and left limb successively and consisted of three 30-second repetitions at the second stiffness level of the stabilographic platform. For the purpose of further material development, persons declaring the right lower limb as the dominant one were selected in order to make the test and the control group more homogeneous. The results were analyzed statistically using the U-Mann-Whitney test assuming the significance threshold of p≤0.05. To assess the correlation, the Pearson's correlation coefficient was used. Results: The analysis of the results showed a statistically significant difference in the overall stability indicator (OSI) of a non-dominant (supporting) limb between the test and the control groups. The abovementioned dependence concerning the overall indicator was affected mainly by stability parameters obtained in the A/P sagittal plane. A correlation between the training history and the overall stability indicator (OSI) in both limbs of karate athletes was also demonstrated. Namely, the increase in training experience of the athlete correlated with the increase in the stability level of both legs. Other results showed no statistically significant differences. Conclusion: 1. Kyokushin Karate master class athletes are characterized by lower level of stability of a non-dominant (supporting) lower limb in comparison with the control group. 2. The more training history experience the athlete has gained, the higher stability level in both lower limbs they have.

scholarly journals Three-dimensional analysis of gait in children and adolescents with juvenile idiopathic arthritis

2020 ◽  
Vol 22 (2) ◽  
Author(s):  
Katarzyna Bazarnik-Mucha ◽  
Sławomir Snela ◽  
Magdalena Szczepanik ◽  
Agnieszka Jarmuziewicz ◽  
Agnieszka Guzik ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Children And Adolescents ◽  
Sagittal Plane ◽  
Gait Pattern ◽  
Rehabilitation Program ◽  
Control Group ◽  
Study Group ◽  
Healthy Children ◽  
Rehabilitation Center ◽  
Abnormal Gait

Purpose: The paper aimed to assess the gait pattern in children and adolescents with juvenile idiopathic arthritis (JIA) treated at the rehabilitation center and to assess changes in this pattern after the end of treatment and 9 months later. Methods: 50 children with JIA were enrolled into the study. 35 healthy volunteers were enrolled into the study for a comparison. Spatiotemporal and kinematic gait parameters were obtained using a movement analysis system. The Gait Deviation Index (GDI) was calculated. The assessment was performed three times: on the day of admission to the rehabilitation center, after the end of a 4-week treatment period and 9 months later. Results: With regard to the majority of spatiotemporal and kinematic parameters, differences in their distribution were highly statistically significant between the study group and the control group (p < 0.001). In two subsequent tests, differences were less significant when compared to the control group (p < 0.01). In the study group, ranges of motion in the sagittal plane in the hip (p < 0.01), knee (p < 0.001) and ankle joints (p < 0.01) increased significantly between tests 1 and 2, and 1 and 3. A significantly lower value of GDI was observed in the study group (right limb; p = 0.036). Conclusions: The gait pattern of children with JIA is significantly different from the one observed in healthy children. A rehabilitation program significantly improved gait in children with JIA, but differences compared to healthy children were still observed, and it indicates that the abnormal gait pattern became permanent in this group of subjects.

scholarly journals Hip abduction and supported standing affect the ranges of hips extension in spinal muscular atrophy patients

2020 ◽  
Author(s):  
Agnieszka Stępień ◽  
Joanna Sikora-Chojak ◽  
Katarzyna Maślanko ◽  
Wojciech Kiebzak
Keyword(s):  
Spinal Muscular Atrophy ◽  
Hip Joint ◽  
Sagittal Plane ◽  
Muscular Atrophy ◽  
Lower Limbs ◽  
Control Group ◽  
Hip Joints ◽  
Hip Abduction ◽  
And Control ◽  
Healthy Participants

Introduction: Recommendations for management of spinal muscular atrophy (SMA) do not contain detailed information about the position of lower limbs during support standing. It has been observed that during the measurement of the range of extension in the hip joint (HE) in SMA patients, the examined limb was often naturally abducted. Aim: The main aim of the study was to compare the values of HE in the sagittal plane and in abduction, and to assess the correlation between the duration of supported standing and HE in SMA patients. Material and methods: The study group consisted of 75 SMA individuals aged 2–22 years and control group consisted of 202 healthy participants. The measurements were performed with the Rippstein plurimeter and goniometer. Results and discussion: Range of HE in SMA patients was larger in abduction than in the sagittal plane. A correlation was noted between the duration of supported standing and HE. Conclusions: Supported standing with hip joint abduction should be used in SMA patients. The obtained results broaden the knowledge about the biomechanics of hip joints in SMA patients.

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