scholarly journals Disease knowledge and preferences for disclosure of information in patients with rheumatoid arthritis

2021 ◽  
Vol 3 (6) ◽  
pp. 3755-3761
Author(s):  
Rafael Pauletti Gonçalves ◽  
Maria Carolina Diana Simões ◽  
Amine Barbella Saba ◽  
Gilberto Santos Novaes
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Duration ◽  
Demographic Data ◽  
Control Group ◽  
Chi Square ◽  
Significance Level ◽  
Level Of Education ◽  
Disclosure Of Information ◽  
Level Of Knowledge ◽  
Strongly Agree

Objectives: To verify the level of knowledge about rheumatoid arthritis (RA) and the patient’s preferences for disclosure of information by the physician in patients with RA, we compared with a control group of patients without RA. Methods: We evaluated 30 patients diagnosed with RA, according to the ACR criteria, and 30 patients with other diseases pared for age, gender, level of education, and disease duration followed in an Out-Patient Service. Clinical-demographic data as age, gender, level of education, and disease duration were obtained from both groups. We applied questionnaires to evaluate the level of knowledge about RA (10 questions) with answers yes or no, and the patient’s preference for disclosure of information by the physician (4 questions) in a Likert scale from a) strongly agree to e) strongly disagree to both groups. The questionnaires were validated for Portuguese by the method of translation and re-translation. The Ethical Committee at the Pontifical Catholic University approved the study, and we obtained informed consent from all patients. When appropriat-ed, statistical analysis of the data included the chi-square test and student’s t-test. The significance level was 0.05. Results: Over 30 patients with RA, 27 patients (90%) were women, the mean age was 50.8 years old, with a mean of 3.03 years on school, and mean disease duration of 10.6 years. The knowledge about RA as a mean reached 5.36 points in 10 as a correct answer in RA patients and 5.13 in controls. Concerning the patient’s preference for disclosure of information by the physician, the results varied between 23.3% and 90% in the answers strongly agree or agree in the group of RA patients and 6.6% to 90% in controls. In a specific question about "patients with RA should not play a role in managing their disease because the physician is the one in charge," 56.6% of RA patients agreed, and 46,6% of controls too. Only one question about patient’s preference for disclosure of information by the physician “When there is more than one way to treat a problem, I should be told about each one” there was a trend to differ between the controls and the RA patients (p=0.06). The analysis of the results showed no statistical difference in answers to the questionnaires between RA patients and controls. Conclusion: Our results showed that RA patients, compared to control patients with other non-rheumatic diseases, do not show differences to the level of knowledge about rheumatoid arthritis (RA) and the patient’s preferences for disclosure of information by the physician.  

Oral and maxillofacial outcomes in children with microcephaly associated with the congenital Zika syndrome

2020 ◽  
Author(s):  
Renato Araújo Ribeiro ◽  
Adriana Mattos ◽  
Marcelo de C Meneghim ◽  
Silvia A S Vedovello ◽  
Técia Mendes Daltro Borges ◽  
...  
Keyword(s):  
Demographic Data ◽  
Clinical Analysis ◽  
Tooth Eruption ◽  
Control Group ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Face Width ◽  
Congenital Zika Syndrome ◽  
Student’S T

Summary Introduction The objective of this study is to assess the oral and maxillofacial characteristics of microcephalic children associated with congenital Zika syndrome (CZS). Methods A cross-sectional, observational study was carried out with 61 patients with microcephaly/CZS born between June 2015 and September 2017 (29 boys and 32 girls, average age of 22.8 months) and a control group with 58 non-CZS children born in the same period (25 boys and 33 girls, average age of 23.8 months). The functional clinical analysis considered the labial and lingual frena, tongue anterior projection, oral escape, palate form, and first tooth eruption. For the craniofacial analysis, facial anthropometric points and the cephalic perimeter at the time were measured. Demographic data were collected from medical records, and a clinical exam was performed in order to register the intrabuccal characteristics and craniofacial measures. The chi-square test and Student’s t-test were used with a significance level of 0.05. Results The narrow palate form, tongue anterior projection, oral escape, and late first tooth eruption were significantly more present in the group with microcephaly/CZS. As for the craniofacial analysis, face width (Bi-Zi), mandible width (Go-Go), height of face upper third (Tr-G), and monthly growth of cephalic perimeter were significantly smaller, whereas height of face lower third (Sn-Gn) was significantly bigger in the group with microcephaly/CZS (P < 0.05). Conclusion Children with microcephaly resulting from a congenital Zika infection showed functional, oral, and maxillofacial changes and smaller facial development in comparison with non-CZS children in the same age group.

scholarly journals Association of interleukin-17A rs2275913 polymorphism with rheumatoid arthritis susceptibility in Sudanese population

2021 ◽  
Vol 9 ◽  
pp. 205031212110202
Author(s):  
Rgda Mohamed Osman ◽  
Mounkaila Noma ◽  
Abdallah Elssir Ahmed ◽  
Hanadi Abdelbagi ◽  
Rihab Ali Omer ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Confidence Interval ◽  
Statistical Tests ◽  
Demographic Data ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Molecular Technique ◽  
Interleukin 17A ◽  
Significant Difference

Objectives: Rheumatoid arthritis is a chronic inflammatory autoimmune disease. This study aimed to determine the association of interleukin-17A-197G/A polymorphism with rheumatoid arthritis in Sudanese patients. Methods: A case–control study was conducted between March and December 2018. Clinical and demographic data of the study participants were collected and analyzed. Polymerase chain reaction restriction fragment length polymorphism molecular technique was done to investigate interleukin-17A-197G/A polymorphisms. All statistical tests were considered statistically significant when p < 0.05. Results: The study population included 266 participants aged between 1 and 85 years, with an average of 40 years, classified into 85 (31.2%) cases (mean age 48.5 ± 11.3 years), and 181 (68.8%) controls (mean age 35.3 ± 15.9 years). The interleukin-17A homozygote AA genotype was more frequent among the control group compared to the case group; 95 (52.5%) and 7 (8.2%), respectively. The homozygote GG and the heterozygote AG genotypes were proportionally not different among the cases and control groups; 13 (54.2%) and 11 (45.8%), and 65 (46.4%) and 75 (53.6%), respectively. According to the distribution of interleukin-17A genotypes, a statistically significant difference was observed among cases with the interleukin-17A AA and AG genotypes, p values 0.001 and 0.004, respectively. For the association interleukin-17A genotypes and family history a negatively significant association was reported (95% confidence interval, –0.219, p value = 0.001). There was also a negatively significant association of interleukin-17A genotypes and anti-cyclic citrullinated peptide (95% confidence interval, −0.141, p value = 0.002). Conclusion: This study is the first study in Sudan established the association between interleukin-17A-197G/A (rs2275913) polymorphisms and susceptibly to rheumatoid arthritis. These findings appeal for further research in Sudan to investigate the exact role of IL-17A in immunopathology and disease severity among Sudanese rheumatoid arthritis

scholarly journals Factors affecting eating habits and knowledge of edible flowers in different countries

2021 ◽  
Vol 6 (1) ◽  
pp. 67-81
Author(s):  
Raquel P. F. Guiné ◽  
Sofia G. Florença ◽  
Ana Cristina Ferrão ◽  
Maša Černelič Bizjak ◽  
Blanka Vombergar ◽  
...  
Keyword(s):  
Questionnaire Survey ◽  
Eating Habits ◽  
Statistical Tools ◽  
Chi Square ◽  
Classification Analysis ◽  
Factors Affecting ◽  
Level Of Education ◽  
Lack Of Information ◽  
Level Of Knowledge ◽  
Classification And Regression

Abstract The use of edible flowers (EF) in gastronomy is gaining popularity; however, there is still a lack of information about the factors that most contribute to the acceptance of this product. Therefore, the objective of this study was to investigate the habits associated with the usage of EF in gastronomy in three different countries (Portugal, Slovenia, and Brazil) and also to evaluate the major determinants for those habits. In addition, the level of knowledge was also investigated, particularly with regard to the aspects such as perceived risks of toxicity and pesticides. For that, a questionnaire survey of self-response was carried out on a sample of 559 participants, from the above-mentioned countries. To analyse the data, basic descriptive statistical tools were used combined with crosstabs and chi-square tests. Finally, a tree classification was performed using the classification and regression trees algorithm. The results revealed that, regardless of the country, the participants were familiar with the use of EF in gastronomy. The participants had, in general, already consumed EF, and their use was more popular between the Portuguese participants, being the Brazilian those who used them less. Significant differences were found between the countries in the form of consumption of EF and also in the types of EF consumed. There were also significant differences regarding the reasons for eating EF. The classification analysis showed that the country and the level of education were the major determinants for the consuming habits and knowledge about EF. This study highlighted that eating habits are very dependent on the customs and traditions of each country and helped understanding the factors that most affect the participants’ attitudes towards the consumption and knowledge of EF.

Effects of Relationship Enrichment Training on Improving Marital Satisfaction of Infertile Couples: A Randomized Control Trial

2021 ◽  
Vol 17 ◽  
Author(s):  
Seyedeh Zahra Masoumi ◽  
Khodayar Oshvandi ◽  
Masoumeh Rostami-Moez ◽  
Arezoo Shayan ◽  
Farideh Kazemi
Keyword(s):  
Marital Satisfaction ◽  
Intervention Group ◽  
Analysis Of Covariance ◽  
Control Group ◽  
Chi Square ◽  
Significance Level ◽  
Significant Difference ◽  
The Mean ◽  
Infertile Couples ◽  
Relationship Enrichment

Background: Infertility can cause low marital satisfaction. Marital satisfaction has an important effect on infertile couples’ health. Objective: This study aimed to assess the effect of relationship enrichment training on improving the marital satisfaction of infertile couples. Methods: This randomized clinical trial was conducted on 50 infertile couples in the infertility center of Fatemieh Hospital in Hamadan, Iran in 2018. Participants were matched for demographic characteristics and randomly assigned to intervention and control groups (each group had 25 couples). Informed consent was obtained from all participants. The Enrich Marital Satisfaction questionnaire and demographic information were used to collect data before the study and two months after the intervention. Two trained midwifery students taught only the intervention group the relationship enrichment topics in seven sessions (each session = 90 minutes). The data were analyzed by SPSS Statistics version 21 using analysis of covariance, independent t-test, chi-square, and Mann–Whitney. The significance level was set at p ≤ 0.05. Results: There was no significant difference in demographic and obstetric information between the two groups (p >0.05). The mean of marital satisfaction in the intervention group significantly increased among women and men from 151.00 ±28.61 to 154.88 ±22.62 and from 152.56 ±27.33 to 159.24 ±22.14, respectively, (p <0.001). Conversely, the mean of marital satisfaction decreased among women and men from 158.13 ±13.86 to 146.25 ±19.53 and from 164.25 ±17.00 to 153.17 ±27.50 in the control group (p=0.02). Conclusion: Relationship enrichment training can be effective in promoting the marital satisfaction of infertile couples. Registration number: The National Center for Strategic Research in medical education, No. 960185.

Resorbable Collagen Barrier Impeding the Extrusion of Obturating Material in Primary Molars Undergoing Resorption – A Randomized Clinical Trial

2021 ◽  
Vol 45 (5) ◽  
pp. 312-316
Author(s):  
Mishra Neha Sanjeev ◽  
Harsimran Kaur ◽  
Sandeep Singh Mayall ◽  
Rishika ◽  
Ramakrishna Yeluri
Keyword(s):  
Test Group ◽  
Primary Molars ◽  
Control Group ◽  
Chi Square ◽  
Significance Level ◽  
Significant Difference ◽  
Chi Square Test ◽  
Group A ◽  
Group B ◽  
And Control

Objective: To evaluate the effectiveness of placing a resorbable collagen barrier in impeding the extrusion of obturation material in primary molars undergoing resorption. Study design: All the 94 canals in 47 mandibular molars were allocated to 2 groups- Group ‘A’- 47 canals with collagen barrier (Test group) and Group ‘B’- 47 canals without collagen barrier (Control group) based on randomization protocol. Pulpectomy was performed and obturation of both test and control canals were radiographically assessed. Pearson’s chi – square test was applied to analyze the results. The significance level was predetermined at p &lt; 0.05. Results: Among the test group, 93.6% of the canals showed no extrusion while, 6.4% showed visible extrusion of the material outside the apex. In the control group, 83% showed no extrusion whereas 17% of the canals showed visible extrusion outside the apex. But no significant difference was noted (p&gt;0.05). Conclusion: The placement of resorbable collagen barrier in the apical third of the canal prevented the extrusion of obturating material beyond the apex in resorbing primary molars.

scholarly journals Evaluation of nasal mucociliary clearance in rheumatoid arthritis: a comparative analysis using saccharin test

2017 ◽  
Vol 5 (11) ◽  
pp. 5026 ◽  
Author(s):  
Shelja Deswal ◽  
Jyoti Yadav ◽  
Mohit Deswal ◽  
Harpreet Singh
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Duration ◽  
Mucociliary Clearance ◽  
Systemic Disease ◽  
Unknown Etiology ◽  
Control Group ◽  
Ciliary Activity ◽  
Multisystem Disease ◽  
Organic Particles ◽  
Nasal Mucociliary Clearance

Background: Rheumatoid arthritis (RA) is a chronic multisystem disease of unknown etiology characterized by persistent inflammatory synovitis, usually involving peripheral joints in a symmetric distribution. RA is a systemic disease often associated with cutaneous and organ-specific extra-articular manifestations the mucociliary clearance system protects the lower respiratory system by trapping and removing inhaled pathogenic viruses and bacteria, in addition to nontoxic and toxic particulates (e.g., pollen, ash, mineral dust, mold spores, and organic particles), from the lungs. Effective clearance requires both ciliary activity and the appropriate balance of periciliary fluid and mucus.Methods: This was a case control study conducted in the Department of Physiology, Pt. B.D. Sharma PGIMS, Rohtak in 50 females of age group 30-50 years. Control group comprised of 25 healthy volunteer females while study group comprised of 25 rheumatoid arthritis female patients with disease duration of more than five years. Proven cases of RA (as per 1987 ACR criteria) were taken with disease duration of more than five years from Rheumatology clinic of Pt. B.D. Sharma PGIMS, Rohtak. Nasal mucociliary clearance time was evaluated by saccharin method.Results: The results of our study showed abnormal mucociliary clearance in rheumatoid arthritis patients.Conclusions: The study shows an abnormal mucociliary clearance in rheumatoid arthritis patients. Impairment of mucociliary clearance seems to be the result of qualitative and quantitative alterations in respiratory secretions.

scholarly journals Increased Risk of Temporomandibular Joint Disorder in Patients with Rheumatoid Arthritis: A Longitudinal Follow-Up Study

2020 ◽  
Vol 9 (9) ◽  
pp. 3005
Author(s):  
Soo-Hwan Byun ◽  
Chanyang Min ◽  
Hyo-Geun Choi ◽  
Seok-Jin Hong
Keyword(s):  
Rheumatoid Arthritis ◽  
Temporomandibular Disorder ◽  
Population Data ◽  
Control Group ◽  
Chi Square ◽  
Kaplan Meier ◽  
Hazard Ratios ◽  
Increased Risk ◽  
Joint Disorder

We evaluated the incidence of temporomandibular disorder (TMD) in patients with rheumatoid arthritis (RA) and examined the association between TMD and RA, through longitudinal follow-up. Population data from the Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2015 was used. From 514,866 subjects, 3122 with RA were matched with 12,488 controls in a 1:4 ratio. The crude and adjusted models (for obesity, smoking, alcohol consumption, blood pressure, blood glucose, total cholesterol, and Charlson Comorbidity Index scores) were calculated. Chi-square tests, Kaplan-Meier (KM) analysis, and two-tailed analyses were used for statistical analysis. Stratified Cox proportional hazard models were used to assess the hazard ratios (HR) and 95% confidence intervals (CI) for TMD in the RA group, compared to those in the control group. The adjusted HR for TMD in RA was 2.52 (95% CI = 1.70–3.74), compared to the control group. The results were consistent with the subgroup analyses, according to age and sex, except in men older than 60 years of age. KM analysis showed similar results. Hence, we found that patients with RA have a higher risk of TMD, and should be observed for symptoms of the initial stage of TMD to prevent the risk of aggravation.

scholarly journals Hubungan Tingkat Pengetahuan tentang HIV/AIDS dengan Sikap Pencegahan HIV/AIDS pada Remaja

2018 ◽  
Vol 1 (1) ◽  
pp. 1-5
Author(s):  
I Ketut Andika Priastana ◽  
Hendra Sugiarto
Keyword(s):  
P Value ◽  
Human Immune System ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Chi Square Test ◽  
Level Of Knowledge ◽  
The Relationship ◽  
Prevention Of Hiv ◽  
Hiv Aids

Introduction. Human Immunodeficiency Virus (HIV) is a virus that attacks the human immune system and Acquired immunodeficiency Syndrome (AIDS) is a collection of symptoms of disease caused by HIV. UNICEF stated that the number of deaths among adolescents due to HIV/AIDS has increased. In Indonesia, cases of HIV/AIDS have begun to attack adolescents, one of the causes of which is a lack of knowledge about HIV/AIDS. This study aims to determine the relationship between the level of knowledge about HIV/AIDS with the prevention attitude against HIV/AIDS in adolescents in Jembrana, Bali, Indonesia. Methods. The research design used was cross sectional, random sampling technique with a sample of 82 people. The statistical analysis used was Chi square test with a significance level of 5%. Results. The results showed that the majority of respondents in the category of sufficient knowledge, namely as many as 53.7% and most had an agreeing attitude towards the prevention of HIV/AIDS as many as 65.9%. The results of the analysis of the Chi square test showed that the relationship between the level of knowledge about HIV/AIDS and the attitude of prevention of HIV/AIDS in adolescents showed p value = 0.001 (p value <0.05). Conclusion. This study found that there was a correlation between the level of knowledge about HIV/AIDS and the attitude of preventing HIV/AIDS in adolescents. Teenagers can improve their knowledge more optimally so that they are more vigilant and supportive of HIV/AIDS prevention.

scholarly journals Knowledge on home management of diarrhea among caregivers of children below five years with diarrhea in Ngandu Location, Nyeri County, Kenya

2020 ◽  
Vol 7 (7) ◽  
pp. 2450
Author(s):  
Leah Wambui Gathogo ◽  
Sherry Oluchina ◽  
Elijah Mwangi
Keyword(s):  
Sample Size ◽  
Household Survey ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Home Management ◽  
Level Of Education ◽  
Low Education ◽  
Level Of Knowledge ◽  
Cross Tabulation

Background: To prevent dehydration and malnutrition in children with diarrhea, it is important they get good management at home. The caregivers should commence home remedies immediately before they seek medical advice. This study assessed the level of knowledge on home management of diarrhea among caregivers of children below five years with diarrhea.Methods: This research applied descriptive cross-sectional study design. The current study was a household survey targeting caregivers of children below five years with diarrhea. The Cochran's sample size formula was used to calculate a sample size of 345 respondents. Purposive sampling was used to recruit respondents in the study. The study employed a researcher- administered semi-structured questionnaire and use of a checklist. Descriptive statistics and chi-square tests were used in the analysis.Results: The study found that that slightly above half 52.2% (n=180) of the respondents had low knowledge on management of diarrhea. There was a significant relationship (χ2=4.044, df=1, p<0.044) between respondent’s’ level of education and knowledge of home management of diarrhea. Cross tabulation showed that 60.2% of those who had low education also had low knowledge.Conclusions: The study concluded that the level of knowledge on home management of diarrhea among caregivers of children below five years with diarrhea was low. Level of education was a significant predictor of knowledge whereby low knowledge was associated with low education. The study recommends enhanced education of mothers on home management of diarrhea by nurses.

scholarly journals Toxicology of Lapachol in rats: embryolethality

2001 ◽  
Vol 61 (1) ◽  
pp. 171-174 ◽  
Author(s):  
M. de O. GUERRA ◽  
A. S. B. MAZONI ◽  
M. A. F. BRANDÃO ◽  
V. M. PETERS
Keyword(s):  
Therapeutic Potential ◽  
Treated Group ◽  
Vehicle Group ◽  
Control Group ◽  
Corpora Lutea ◽  
Water Control ◽  
Chi Square ◽  
Significance Level ◽  
Chi Square Test ◽  
Teratogenic Potential

Lapachol is a naphtoquinone with therapeutic potential against enterovirus, Chagas disease and is also used as an antimalarial and antiinflamatory agent. In order to study teratogenic potential of Lapachol, pregnant Wistar rats were treated with 0.5 ml of distilled water (control group); 0.5 ml of hydroalcoholic solution (vehicle group) and 10 mg of Lapachol in 0.5 ml of hydroalcoholic solution (treated group) by oral gavage from the 8th to the 12th day of pregnancy. The following variables were observed: maternal body weight on days 1, 6, l5 and 21 and food intake on days 2, 6, 15 and 21 of pregnancy. The number of live and dead fetuses and the sites of resorptions were counted. The ovaries were weighed and the corpora lutea were counted. Data were analyzed by ANOVA-one way, Dunnett test and the chi square test. Significance level test alpha = 0.05. Results have shown that mothers were unaffected but there were a 99.2% of fetus mortality, indicative of a strong abortifacient effect of Lapachol in rats.

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