scholarly journals UNDERSTANDING FIBROIDS IN LIGHT OF AYURVEDA

Author(s):  
Mary Blossom CJ ◽  
Giby Thomas ◽  
Jyothi PK

The changing lifestyle and dietary pattern has given way to many gynecological problems in females. Uterine fibroids are one of leading concerns for women in reproductive age. Though uterine fibroids are non- cancerous in character; they exhibit a wide range of symptoms like dysmenorrhea, menorrhagia, metrorrhagia, low backache etc. It significantly hampers the general health and quality of life in women causing great mental agony. Contemporary treatment protocols include hormonal therapy, hysterectomy, myomectomy and uterine artery embolization. Reluctance to undergo prolonged hormone therapy, the fear of surgery brings more and more patient to Ayurveda. Hence more systematic studies in conservative management in these areas of Stree Roga are need of the hour. Ayurveda classics mention various pathological conditions that have features similar to fibroids. Owing to its muscular origin, with slow growth may be better compared to Granthi in Garbhasya. In the modern era of busy lifestyle, intake of junk food, lack of exercise etc had lead to Agnivaishamya and Ama formation. This in turn vitiates Doshas like Kapha and Vata and Dushyas like Rasa, Raktha, Mamsa, Medas and Arthava resulting in Dhatwagnimandya leading to formation of Garbhasayagranthi. The treatment approach is directed towards reducing size of fibroids using Ushna, Tiskhna, Lekhana Dravyas along with management of symptoms. The inevitable roles of Vata in Yoniroga is also taken into account in its management. Combining different treatment aspects of Granthi and Yoni Roga Chitksa, a unique approach towards the management of its varied presentations added on with lifestyle modification can contribute to healthy social life. The current article focuses and explores potentials of Ayurveda in different aspects of uterine fibroid.

2021 ◽  
pp. 1-3
Author(s):  
Uwe Gieler

<b>Background</b>: Hidradenitis suppurativa is a debilitating disease related to a great psychosocial burden in affected patients and subsequently also people around them. Patients’ partners as caregivers may indirectly experience wide range of devastating effects of the disease on their emotional and social life. <b>Objective:</b> The purpose of this study was to determine the QoL impairment in HS patients’ partners and to identify its aspects that are affected the most. Correlation between QoL burden and disease severity, duration, sex, age and smoking was also assessed. <b>Methods:</b> A total of 50 HS sufferers were assessed according to disease severity and their partners’ QoL was determined using the Family Dermatology Life Quality Index questionnaire. <b>Results:</b> The mean FDLQI for patients’ partners was 8.7 ± 6.8 points, indicating generally a moderate effect of HS on their life. Quality of partners’ life correlated significantly with disease severity but no correlation was found according to other factors. <b>Conclusion:</b> Hidradenitis suppurativa is a highly psychologically devastating disease not only for patients but also for their partners. It occurred to diminish partners’ QoL mostly by increasing daily expenditure but also other problems were often reported. Clinicians should be aware of these psychosocial implications, in order to provide optimal therapy of HS affected families by a multidisciplinary specialized management addressing both, patients and their cohabitants simultaneously.


2016 ◽  
pp. 94-97
Author(s):  
O. Makarchuk ◽  
◽  
G. Gavrilyuk ◽  

One of the most common benign hyperproliferative diseases of the female reproductive organs are uterine leiomyoma, the frequency of which, according to various literature in women of reproductive age is between 20% and 40%, and is the main indication for surgery, including removal of the organ. Long-term effects of surgical interventions for uterine fibroids have been the subject of numerous debates. In modern literature is not much research on the assessment of the quality of life both in organ treatment of uterine fibroids, and after surgical recovery. Quality of life have undoubtedly significant prognostic value and can be used in selecting the optimal treatment of uterine fibroids, as well as the development of individual approach to postoperative rehabilitation of patients. The objective: was the study of quality of life and the search for possible ways to improve in women after surgical healing uterine fibroids. Materials and methods. A survey of 80 women of reproductive age (study group), which was conducted without hysterectomy applications. Clinical and laboratory examination conducted in the dynamics of the postoperative period and at 6, 12 months and 3 years after surgical recovery. Assessment of comparative analysis require further formation of two groups comparing 20 patients with myoectomy and 20 women with no uterus amputation supravaginal applications. The control group consisted of 20 healthy patients. Assessment of quality of life survey conducted by using common clinical trials and monitoring at the individual questionnaire MOS 36- Item Short-Form Health Survey- MOS SF-36. Statistical analysis of the survey results was carried out using the software package Microsoft Office Excel and Statistica 6.0 for Windows. Results. In women, the main indicators of psycho-emotional and vegetative manifestations were most pronounced immediately after surgery and remained stable in three years with no significant deviations in the comparison group. Among the most frequently observed fatigue (76.25%), sleep disorders (88.75%), irritability and mood changes (76.25%) and emotional lability, anxiety and depressive symptoms. Of The results of evaluation of quality of life should be noted that first disturbed functioning role of women because of poor physical and emotional state, as evidenced by the significant differences obtained on the scale of General Health (GH) (overall health). Three years after the rapid improvement in women’s core group established stable condition posthisterektomy pronounced effect on quality of life. Thus, in total 33.75% of the principal groups characterized as low quality of life, compared with 5.0% of patients in the control group and 10,0% of women with myoectomy. Conclusions. The highest level of dissatisfaction with life studied patients presenting in health – 28.75% (23) cases, slightly less professional – 22.5% (18), emotional – 17.5% (17) and as in the sexual sphere – 13.75% (11) cases. That associated complications related symptoms posthisterektomy syndrome, increases the level of stress and hysterectomy as the body creates prerequisites for psychosomatic disorders. This action provides additional risk factors for the development of psychosocial distress in this group of patients. Key words: uterine fibroids, hysterectomy, posthisterektomy syndrome, psychosomatic disorders, quality of life.


CNS Spectrums ◽  
2018 ◽  
Vol 23 (1) ◽  
pp. 108-108
Author(s):  
Sultana Jahan ◽  
Sailaja Bysani

AbstractEDUCATIONAL OBJECTIVESAt the conclusion of the session, the participant should be able: 1) To recognize emetophobia & how it can lead to significant impairment & reduce quality of life; 2) To appreciate the prevalence of emetophobia among the general population, 3) To learn that the selective serotonin reuptake inhibitor sertraline can be effective for emetophobia; 4)Need for more research.INTRODUCTIONEmetophobia is an intense, irrational fear of vomiting. The prevalence rate of emetophobia in a community sample has been estimated to 8.8 % with a female to male ratio 4:1: It can occur at any age and can have a chronic course affecting one’s academic/career, family, and social life.METHODSCase 1: B. was a 7 year old female referred by her pediatrician for psychiatric evaluation for her intense fear ofvomiting. Mother shared that B’s overwhelming fear of vomiting started when she was 6 years old and it may have stemmed from an incident when one of B’s cousins threw up inside their van. At school, B constantly monitored whether or not anybody was getting sick around her. If she found out, someone was sick she began screaming and crying. B’s academic performance was negatively affected due to her intense irrational fear.Case 2: P was a 12 year male patient referred by his pediatrician for psychiatric evaluation after receiving 4 days inpatient treatment on the pediatric unit for dehydration. Patient reported that he was afraid of vomiting and gradually stopped eating and drinking & became so dehydrated that he was hospitalized. Several months prior to his hospitalization he had suffered from theflu & during that time he had intense vomiting and since then he has been fearful of a recurrence of the vomiting.After a complete psychiatric evaluation, a diagnosis of emetophobia was established for each patient. Both patients were treated with sertraline.RESULTSB and P both started with initial dose of sertraline 12.5mg daily and then increased gradually over a period of next few months. They responded well with sertraline. B and P continued sertraline 50mg daily and 25mg daily as a maintenance treatment respectively. At 1 year follow up visit both of them were symptoms free.CONCLUSIONSEmetophobia is a common and chronic debilitating mental illness. Still there are no treatment protocols and randomized controlled trials for the treatment of emetophobia. CBT/Exposure-based therapies are the most commonly used approaches for emetophobia per literature. More studies are needed for a better understanding of eremophobia, which is relatively deserted illness although it can cause as much suffering as other major psychiatric disorders do and any patient presenting with these symptoms deserve to be evaluated an managed with scientific understanding and guideline.Funding AcknowledgementsNo funding.


2016 ◽  
Vol 23 (3) ◽  
Author(s):  
H. M. Havrylyuk ◽  
O. M. Makarchuk

Recently, it has been noticed a great number of uterine fibroids in women with unrealized reproductive function; moreover, the number of combined forms of hyperplastic processes of the reproductive system in 20-25% of women under 30 years of age and 60% of women over 40 years of age is constantly growing creating a favourable background for cancer. It is also known that women with hyperplastic processes suffer from psycho-emotional disorders both before surgeries and after surgical recovery; many of them are diagnosed with adjustment disorder. As many researches note, the main psychotherapeutic aspects include passive view of life, increased anxiety, tendency to dependent behaviour, rejection of own body, protective behaviour and problems with self-assessment. It should also be noted that a comprehensive study of clinical and laboratory data and subjective criteria of life quality is essential in assessment of the feasibility of hysterectomy in women of reproductive age, even if they do not plan to bear children in the future. The objective of the research was to estimate life quality as well as to improve the system of dispensary observation and rehabilitation of women who underwent uterine surgery.Materials and methods. There was performed a comprehensive examination and surgical treatment of 60 women of reproductive age with uterine fibroid who underwent hysterectomy with preservation of appendages. We used modern high quality endocrinological and instrumental techniques. The assessment of the received data was made immediately after surgery, 6 and 2 months, 3 and 5 years after surgery. Quality of life was studied on the basis of a comprehensive assessment using the modified scale of the Nottingham Health Profile and the study of such important indicators as energy, sleep, emotional reactions, social isolation, physical activity, pain. All statistical analysis was performed using a standard package “Statistica for Windows – 6.0”.Results and discussion. On the basis of anamnestic data of patients we revealed health deterioration with high rates of liver and gastrointestinal tract disorders, metabolic disturbances (obesity, hypertensive disorders, fibrocystic breast disease), metabolic-endocrine changes and surgery. Reproductive health in women with uterine fibroid was characterized by long establishment of regular menstrual cycle, its breach in the period of puberty, inflammatory diseases of the genital organs, benign ovarian tumours and their surgical removal, inadequate reproductive behaviour with absent or delayed implementation of reproductive function and induced abortion. 12 months and especially 5 years after surgery there was noticed a progressive deterioration of the ovarian function, which was reflected as the reduction in their volume due to the reduction in the number and size of follicles, deterioration of blood supply to the ovaries, decreased blood flow in the internal iliac artery basin. It should also be noted the progressive hypestrogenism; in addition, there was a clear correlation with the age of the woman, who underwent surgical operation. Changes in life quality of patients with hyperplastic processes of the uterus were manifested in the postoperative period as follows: a decrease in physical activity (43.33% of cases), increased sexual dysfunction (36.66%), inhibition of mental state, conflict-orientated social behaviour, weakening of role functions and subjective deterioration of health and life quality (51.66% of cases).Conclusions. Thus, surgery on uterine fibroids with total or subtotal hysterectomy contributes to interference in a complex neuroendocrine interaction between hypothalamus, pituitary, ovaries, adrenal cortex, thyroid gland and affects the blood supply, innervation, and lymph efflux in the pelvic floor; therefore, postoperative syndromes are polyglandular and polysystemic. Long-term effects after surgery are accompanied by progressive hypestrogenism, decrease in the ovarian function (the reduction in their volume observed during ultrasound examination), reduction in the number and size of follicles, deterioration of blood supply to the ovaries, low blood supply to the internal iliac artery basin.


2014 ◽  
Vol 31 (3) ◽  
pp. 349-376 ◽  
Author(s):  
Chris Shilling ◽  
Philip A. Mellor

Sociological studies of sport have established their subject matter as significant to a wide range of sociocultural concerns. Despite a broad consensus about its global importance, however, the reasons for the particular, even ‘extraordinary’, societal importance of sport today remain deeply contested. Most studies account for it by highlighting its entanglement within a range of secular phenomena including state building, rationalization, biopolitical regulation, and the ‘controlled-decontrolling’ of bodies and affects. Occupying a more marginal position within the discipline, others focus on the religious or quasi-religious characteristics of sport. Our paper suggests that neither of these positions, on their own, is best placed to capture the nature and implications of sport’s particular centrality to social life. Proposing a new theoretical approach to the subject that places competing conceptions of what we refer to as the ‘sporting sacred’ at the center of discussion, we outline, via a reconceptualization of the writings of two major classical theorists, Durkheim and Weber, a number of contrasting modalities through which sport is prized within contemporary society. These modalities, which embrace both secular and religious phenomena, can, we suggest, provide new insight into the divergent paths along which sports are being ‘pulled’ and steered in the modern era.


2021 ◽  
pp. 89-94
Author(s):  
Olha Proshchenko ◽  
Borys Ventskivsky ◽  
Iryna Ventskivska

Today, there are more and more reports of an increase in the proportion of patients with uterine fibroids (up to 45 %), in whom hysterectomy (HE) remains the only radical method of recovery. Over the past decades, views on this operation have changed significantly. HE and its influence on somatic and psychological status, psychogenic changes and vegetative-neurotic manifestations associated with postoperative acute circulatory ischemia of ovarian tissue have become the subject of scientific exchange in many discussion panels.The article presents data from an experimental psychological study, assessment of the severity of urogenital dysfunction using the standardized POP-Q system, characteristics of quality of life parameters, indicators of carbohydrate and lipid metabolism both at the stage of preoperative followup and within 12 months, 3 and 5 years after surgery. in 80 women of reproductive age with uterine fibroids who underwent vaginal hysterectomy.The comparison group included 60 patients with abdominal hysterectomy. As a result of the studies carried out using experimental psychological methods, the dominance of asthenic, anxiety and depressive disorders should be noted. The most common symptoms were decreased performance, mood, emotional lability, dyssomnia, decreased memory and concentration.The study of the parameters of the quality of life made it possible to note the lowest indicators in the older age category of the main group, low levels of parameters were recorded in relation to «physical» and «sexual health», the sphere of interpersonal relationships suffered less.After GE, an increase in body mass index, systolic and diastolic blood pressure, an increase in proinsulin and HOMA index, as well as very low density lipoprotein cholesterol and an atherogenic index were recorded.


2020 ◽  
Author(s):  
Zi-Lin Li ◽  
Tung-Yung Huang ◽  
Yih Ho ◽  
Ya-Jung Shih ◽  
Yi-Ru Chen ◽  
...  

Uterine fibroids, also known as uterine leiomyoma is the most common benign tumor of the uterus found in women of reproductive age. Uterine fibroids are the cause of major quality-of-life issues for approximately 25% of all women who suffer from clinically significant symptoms of uterine fibroid. Despite the prevalence of fibroid, currently, there are no effective treatment options for fibroid. The lack of understanding of the etiology of fibroid contributes to the scarcity of medical therapies available. Sex steroid hormones, dysregulation of cell signaling pathways, miRNA expression, and cytogenetic abnormalities may all implicate in fibroid etiology. Several herbal medicines have been used as anti-inflammation and antitumor agents. All of them have a common capability to inhibit expression of pro-inflammatory cytokines, proliferative genes, and pro-angiogenetic genes. Exploring herbal medicines as remedies lighten the hope of treatment. In the current review article, we discuss signal transduction pathways activated herbal medicines. We also address the possibility of using herbal medicines for uterine fibroid treatment.


Author(s):  
Jayshree J. Upadhye ◽  
Chaitanya A. Shembekar

Background: Polycystic ovarian syndrome (PCOS) is an endocrine disorder which affects the adolescent girls It affects 5% to 10% of women in their reproductive age. Awareness and accurate diagnosis is the first step in managing PCOS as it improves quality of life of the patient. The study was conducted to assess the knowledge on PCOS among the medical students.Methods: Survey of 200 girls was done to assess the knowledge on the polycystic ovarian syndrome among the medical students of different colleges studying in 1st, 2nd, and 3rd year. The data was collected from the students by using structured questionnaire.Results: In present study, 51% girls had normal BMI, 19.5% were overweight, 16.5% were obese while 13% were underweight. 33.5% females had acne, 16% had irregularity of menses, 5% had hirsutism while 2% had infertility. In present study, 33% adolescent and young girls had information about PCOS from teacher, 19% got information from friend, 11.5% got information from a doctor, 3.5% got information from newspaper while 5% got information from internet. 28% adolescent and young girls were unaware of PCOS.Conclusions: Thorough knowledge of the disorder and counseling for adolescents should be included in the curriculum which will provide awareness towards the disorder and lifestyle modification. Accurate diagnosis at a younger age may be a key.


Author(s):  
Ashish R. Kale

Background: Present study was a randomised prospective observational study carried out at Ashakiran Hospital and IVF centre Pune, Maharashtra, India to evaluate the efficacy, safety, and quality of life by using Ulipristal acetate 10 mg and Mifepristone 25 mg daily doses to treat uterine fibroids of two subgroups involving fibroids <3 cm and fibroids 3 to 5 cm all are in reproductive age group with symptomatic in nature over 3 months.Methods: A total number of 40 patients were recruited in the study of which they were divided into two groups according to the size of the fibroid as <3cm and 3-5cm as seen on transvaginal as well as transabdominal ultrasound. Further they were randomly assigned to either mifepristone or ulipristal orally with each category having 10 patients each to assess changes in fibroid size, in symptomatic pain reduction, menorrhagia and in quality of life.Results: The 25-mg dosage of Mifepristone is shown to be a good and effective way of treatment in fibroids less than 3 cm in achieving 40% reduction in size and 50% reduction in menorrhagia as compared to Ulipristal 10 mg which acts better in other subgroup of size 3-5 cm of fibroids.Conclusions: Still larger RCTs are needed to study the long-term benefits of these drugs.


Cleft lip and palate are the most frequent anomalies of the face, which can compromise normal functions in addition to interfering with the patient's quality of life. Oral health problems can impact daily life, being more striking for these patients due to their functional and aesthetic changes. The aim of the study was to evaluate the oral health-related quality of life of patients with cleft lip and/or palate at the Center for Attention to Face Defects (CADEFI/IMIP-PE). The sample consisted of 348 patients, 174 aged 8 to 12 years and 174 aged 13 to 18 years. The collection instrument used to measure quality of life was PedsQL 4.0. Data analysis was performed using the STATA 9.0 software, descriptive, observing the absolute and relative frequencies in relation to the demographic and clinical characteristics of the sample and measures of central tendency for the PedsQL 4.0 score and domains. Poisson regression with robust variance was performed to associate the total scores and individual domains of the PedsQL 4.0 with the types of cravings, their prevalence and demographic conditions. Subsequently, the selected variables were tested in the adjusted multivariate model, which could only be maintained if the variables presented p≤ 0.05. Robust rate ratios (RTR) and 95% confidence intervals (95% CI) were calculated. Practically all respondents (99.9%) reported some impact in at least one of the instrument's domains. Children aged 13 to 18 years had a positive impact, better quality of life, compared to those aged 8 to 12 years. Multidisciplinary treatment protocols for the rehabilitation of patients with cleft lip and palate seek to restore function and aesthetics, helping to overcome stigma and integrating into social life, which can justify the favorable results of the assessment of the quality of life of these patients


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