Increasing running volume elicits hematological changes in trained endurance runners: a case study (El aumento del volumen de entrenamiento de carrera induce alteraciones hematológicas en corredores entrenados: un estudio de caso)

Corpuscular Hemoglobin ◽

Endurance Running ◽

Mean Cell Volume ◽

Endurance Runners ◽

Hematological Indicators ◽

Hematological Changes ◽

Trained Runners

Abstract. Background: Endurance running training induces several hematological changes that increase the capture, transport and delivery of the oxygen to the exercising muscles. Objective: This study aimed to verify how a dramatic increase in running volume induced new alterations in several hematological indicators in previously trained endurance runners. Methods: Three subjects (PL: 26 years, 169,5 cm; HP, 27 years, 167,9 cm; MC, 27 years, 180,7 cm) running 10-12 km/day, increased their running volume to prepare the participation in a 100-km ultra-marathon. New training program included 10-12 training sessions per week, totalizing 200-260 km. Average daily running volume was 35.8±6.2 km. The parameters analyzed were: hemoglobin, erythrocytes, hematocrit, mean cell volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), leukocytes, neutrophils, eosinophils, lymphocytes, and monocytes. Results: Erythrocyte count, hemoglobin, and hematocrit decreased 6.5%, 5.1% and 6.7%, respectively for the average of the three runners. Leukocytes, neutrophils, eosinophils, lymphocytes, and monocytes showed different alterations among participants with all the values remaining within normal reference values. Conclusion: Well-trained runners show further hematological alterations when training volume is dramatically increased, which can be seen as the specific adaptation to the new training level. It seems that hemogram is more sensitive than leucogram to the increase in running volume.Resumen. Antecedentes: El entrenamiento de resistencia aeróbica induce varios cambios hematológicos que aumentan la captura, el transporte y la entrega del oxígeno a los músculos en ejercicio. Objetivo: El objetivo de este estudio fue verificar cómo un aumento dramático en el volumen de corrida indujo nuevas alteraciones en varios indicadores hematológicos en corredores previamente entrenados. Métodos: Tres sujetos (PL: 26 años, 169,5 cm, HP, 27 años, 167,9 cm, MC, 27 años, 180,7 cm) corriendo 10-12 km / día, aumentaron su volumen de carrera para preparar la participación en un ultra maratón de 100 km. El nuevo programa de entrenamiento incluyó 10-12 sesiones de entrenamiento por semana, totalizando 200-260 km. El promedio diario de volumen de carrera fue de 35,8 ± 6,2 km. Los parámetros analizados fueron hemoglobina, eritrocitos, hematocrito, volumen celular medio (MCV), hemoglobina corpuscular media (MCH), concentración media de hemoglobina corpuscular (MCHC), leucocitos, neutrófilos, eosinofilos, linfocitos y monocitos. Resultados: El recuento de eritrocitos, la hemoglobina y el hematocrito disminuyeron 6,5%, 5,1% y 6,7%, respectivamente, para el promedio de los tres corredores. Los leucocitos, neutrófilos, eosinofilos, linfocitos y monocitos mostraron diferentes alteraciones entre los participantes con todos los valores restando dentro de los valores normales de referencia. Conclusión: Corredores bien entrenados muestran alteraciones hematológicas adicionales cuando el volumen de entrenamiento aumenta drásticamente, lo que puede ser visto como la adaptación específica al nuevo nivel de entrenamiento. Parece que el hemograma es más sensible que el leucograma al aumento en el volumen de entrenamiento de carrera.

Blood Donation in Nigeria: Standard of the Donated Blood

Journal of Laboratory Physicians ◽

10.4103/0974-2727.105589 ◽

2012 ◽

Vol 4 (02) ◽

pp. 094-097 ◽

Cited By ~ 4

Author(s):

Nwogoh Benedict ◽

Awodu Omolade Augustina ◽

Bazuaye Godwin Nosakhare

Keyword(s):

Blood Donation ◽

Hematological Parameters ◽

Corpuscular Hemoglobin ◽

Mean Cell Volume ◽

Benin City ◽

Cell Counts ◽

Significant Difference ◽

The Mean

ABSTRACT Objective: The objective was to determine the basic hematological parameters of remunerated blood donors in Benin City and to compare them with those of voluntary donors. Materials and Methods: This is a prospective study conducted in a tertiary health facility in Benin City. Pretransfusion samples were obtained from blood bags after gentle mixing and analyzed for hematological parameters. Samples were analyzed using the hematology autoanalyzer MODEL SYSMEX KN21. Result: A total of 215 samples were obtained comprising 160 remunerated (paid) and 55 voluntary donor samples. In the paid donors, the mean hemoglobin concentration (Hb) and hematocrit (HCT) 7.7±2.9 and 28.8±8.5 respectively. This was significantly lower than those of voluntary donors who had 13.9±1.2 and 42.2±3.3 with P < 0.001. The mean values of the red cell counts (RBC), white cell counts (WBC), mean cell volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) were significantly lower in paid donors as P-values were <0.001. MCV was significantly low but not compared to the other parameters as P=0.04. There was no significant difference in the platelet count. Conclusion: Paid donors in Benin City have significantly lower hematological parameters than controls.

Hematological Changes and Severity of Aggression in Black and White Forensic Patients

Psychological Reports ◽

10.2466/pr0.1993.73.3f.1105 ◽

1993 ◽

Vol 73 (3_suppl) ◽

pp. 1105-1106 ◽

Cited By ~ 1

Author(s):

Reuben T. Spitz ◽

Hilliard G. Foster ◽

Marc Hillbrand

Keyword(s):

White Male ◽

Blood Cell Count ◽

Corpuscular Hemoglobin ◽

Mean Values ◽

Forensic Patients ◽

Black And White ◽

Red Blood Cell Count ◽

Analysis of hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin concentration, and red blood-cell count for a group of 46 black and 59 white male forensic patients showed significant hematological differences between the groups, with white patients demonstrating higher mean values for all four measures.

Comparison of Hematological and Biochemical Profiles of Late Pregnant and Non-Pregnant Mares

jurnal veteriner ◽

10.19087/jveteriner.2021.22.1.1 ◽

2021 ◽

Vol 22 (1) ◽

pp. 1-7

Author(s):

Murat Onur Yazlik ◽

Ezgi Dikmeoglu ◽

Arzu Esen ◽

Ufuk Kaya ◽

Özgenur Kafkas ◽

...

Keyword(s):

Blood Cell ◽

Cell Count ◽

Biochemical Parameters ◽

Clinical Practices ◽

Blood Cell Count ◽

Corpuscular Hemoglobin ◽

Mean Cell Volume ◽

Pregnancy Status

The maternal body must adapt to fetal growth and development during the state of pregnancy for successful foal and mother. Pregnancy status as in other mammals is related to physiology and hematology. This study aimed to compare the hematology profiles and biochemical parameters of late pregnant and non-pregnant mares. Twenty-two mares were included in the study. Mares were divided into two groups according to the pregnancy status. Hematology profile and biochemical parameters were analyzed from blood samples collected from the jugular vein. All data were analyzed using Stata 12/MP4. White blood cell count, lymphocyte, red blood cell count, hemoglobin concentration, hematocrit, monocyte and percentage of monocyte were significantly lower in non-pregnant mares compared to late pregnant mares (P<0.05). No significant differences were noted in values of neutrophil, eosinophil, mean cell volume, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, platelet, mean platelet volume, red cell distribution width in both groups (P>0.05). On the other hand, biochemical parameters analysis showed that calcium, total bilirubin, and triglyceride concentrations were greater in late pregnant mares (P<0.05). However, urea, albumin, cholesterol, and magnesium concentrations were similar among groups (P>0.05). In conclusion, the present study showed hematology profile and biochemical parameters differences in late pregnant and non-pregnant mares. These values could be useful in clinical practices to assess the situation of late pregnant mares.

Age-Sex Related in Hematological Values of Sandalwood Pony Horses (Equus caballus) in East Sumba, NTT

Journal of Veterinary and Animal Sciences ◽

10.24843/jvas.2020.v03.i02.p06 ◽

2020 ◽

Vol 3 (2) ◽

Author(s):

Cynthia Dewi Gaina ◽

Antin Y. N. Widi ◽

Agus Saputra

Keyword(s):

Hematological Parameters ◽

Age Groups ◽

Physiological Status ◽

Published Data ◽

Corpuscular Hemoglobin ◽

Hematological Indicators ◽

Age And Sex ◽

Hematological Values

Normal hematological values need to be defined for each category of horse, like age and sex to obtain precise diagnostic results. No published data on hematology exist for Sandalwood horses that are extensively reared in East Sumba, NTT. The main objective of this research was to compare the hematological characteristic of horse group based on age and sex. Blood samples from sixteen horses were collected based on sex into male (n=6), female (n=10) and age groups of 2-3 years (n=4) and 6-10 years old (n=12). About 3 ml of blood sample was collected aseptically from jugular vein of each of these animals in sterile vacutainer tube. The following variables were measured: erythrocyte, leucocyte, platelet, hemoglobin (Hb), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and mean platelet volume (MPV). These hematological parameters were calculated with the automatic hematology analyzer at Health Laboratory in Kupang, NTT. This result was analyzed by using student T-test and analysis of variance. These results would contribute to better understanding of the hematological indicators for estimating the physiological status of Sandalwood horse in East Sumba as it can be used as valuable information of its health physiological status.

Applying Nanotechnology for Environmental Sustainability - Advances in Environmental Engineering and Green Technologies ◽

Copper and Copper Nanoparticles Induced Hematological Changes in a Freshwater Fish Labeo rohita – A Comparative Study

10.4018/978-1-5225-0585-3.ch015 ◽

2016 ◽

pp. 352-375

Author(s):

Kaliappan Krishnapriya ◽

Mathan Ramesh

Keyword(s):

Blood Cells ◽

Mean Corpuscular Volume ◽

Labeo Rohita ◽

White Blood Cells ◽

Mean Corpuscular Hemoglobin Concentration ◽

Corpuscular Hemoglobin ◽

Treated Fish ◽

In the present study, fish Labeo rohita were exposed to 20, 50 and 100 µg/L of both Cu NPs and copper sulphate (CuSO4, bulk copper) for 24 h and hematological profiles were estimated. A significant (P< 0.01) change in the hemoglobin (Hb), hematocrit (Hct), white blood cells (WBC) and Mean Corpuscular Volume (MCV) levels were observed in all the three concentrations of both bulk and Cu NPs treated fish when compared to control groups. However a non significant change in red blood cells (RBC) (20 and 50 µg/L Cu NPs) and mean corpuscular hemoglobin (MCH) (20 and 50 µg/L bulk Cu) were observed. The alteration in Mean Corpuscular Hemoglobin Concentration (MCHC) value was found to be non significant both in bulk and Cu NPs treated fish. The alterations of these parameters can be used as a potential indicator to examine the health of fish in aquatic ecosystem contaminated with metal and metal based nanoparticles.

Blood: tests used to assess the physiological and immunological properties of blood

AJP Advances in Physiology Education ◽

10.1152/advan.00079.2015 ◽

2016 ◽

Vol 40 (2) ◽

pp. 165-175 ◽

Cited By ~ 2

Author(s):

J. G. Quinn ◽

E. A. Tansey ◽

C. D. Johnson ◽

S. M. Roe ◽

L. E. A. Montgomery

Keyword(s):

Undergraduate Students ◽

Blood Parameters ◽

Corpuscular Hemoglobin ◽

Mean Cell Volume ◽

Normal Ranges ◽

Appropriate Treatment ◽

Autoimmune Conditions ◽

Ease Of Access

The properties of blood and the relative ease of access to which it can be retrieved make it an ideal source to gauge different aspects of homeostasis within an individual, form an accurate diagnosis, and formulate an appropriate treatment regime. Tests used to determine blood parameters such as the erythrocyte sedimentation rate, hemoglobin concentration, hematocrit, bleeding and clotting times, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, mean cell volume, and determination of blood groups are routinely used clinically, and deviations outside the normal range can indicate a range of conditions such as anemia, pregnancy, dehydration, overhydration, infectious disease, cancer, thyroid disease, and autoimmune conditions, to mention a few. As these tests can be performed relatively inexpensively and do not require high levels of technical expertise, they are ideally suited for use in the teaching laboratory, enabling undergraduate students to link theory to practice. The practicals described here permit students to examine their own blood and that of their peers and compare these with clinically accepted normal ranges. At the end of the practicals, students are required to answer a number of questions about their findings and to link abnormal values to possible pathological conditions by answering a series of questions based on their findings.

Hematological changes in deer mice acclimated at different ambient temperatures

American Journal of Physiology-Legacy Content ◽

10.1152/ajplegacy.1960.198.1.195 ◽

1960 ◽

Vol 198 (1) ◽

pp. 195-199 ◽

Cited By ~ 5

Author(s):

John A. Sealander

Keyword(s):

Deer Mice ◽

Mean Corpuscular Hemoglobin Concentration ◽

Corpuscular Hemoglobin ◽

Ambient Temperatures ◽

Significant Difference ◽

Similar Temperature ◽

The Mean ◽

Deer mice ( Peromyscus maniculatus and Peromyscus leucopus) were acclimated at temperatures of 5° ±0.5°C and 30°±0.5°C for various intervals with periods at 20°±0.5°C preceding the cold and warm acclimation periods. Hemoglobin concentrations, hematocrits and erythrocyte diameters were measured on a group of nonsplenectomized mice and on another group of splenectomized mice which were subjected to similar temperature conditions. It was found that there were significant increases in hemoglobin and hematocrit values with acclimation at 5°C, which were more marked in the splenectomized mice. Differences in hemoglobin concentrations and hematocrits were significant between 5° and 30°C, but differences were not as apparent between mice at 30°C and those exposed at 20°C. There were no significant changes in erythrocyte diameters, although the mean corpuscular hemoglobin concentration was significantly lower in all of the splenectomized mice as opposed to the nonsplenectomized ones. It is suggested that splenectomy in some way enhances erythopoiesis in response to low temperature since there was no significant difference in hematocrits of nonsplenectomized and splenectomized mice exposed at 20°C prior to cold acclimation.

THE INFLUENCE OF THE PHYSIOLOGICAL STATE OF RABBITS ON HEMATOLOGICAL INDICATORS WITH CHANGES IN THE AREA OF THE PLANTARY SURFACE OF THE FEET

Scientific Notes Kazan Bauman State Academy of Veterinary Medicine ◽

10.31588/2413-4201-1883-246-2-262-267 ◽

2021 ◽

Vol 246 (2) ◽

pp. 262-267

Author(s):

N.S. Khokhlova ◽

◽

V.V. Semenyutin ◽

◽

Keyword(s):

Hematological Parameters ◽

Physiological State ◽

The Body ◽

Corpuscular Hemoglobin ◽

Plantar Surface ◽

Hind Limbs ◽

Pregnancy And Lactation ◽

Hematological Indicators

The influence of the physiological state of rabbits (pregnancy and lactation) on the hematological parameters of blood during changes in the area of the plantar surface of the feet of the hind limbs in conditions of cage keeping was studied. In the body of pregnant females, with the appearance of signs of hyperkeratosis and alopecia in the studied area of the feet, an increase in hemoglobin level occurs, an increase in MCH (mean corpuscular hemoglobin), MCV (Mean Corpuscular Volume), MCHC (corpuscular hemoglobin concentration) occurs, followed by a decrease in the development of hemorrhagic changes. The level of red blood cells has slight fluctuations. In lactating females, with the occurrence of alopecia and hyperkeratosis, an increase in the level of erythrocytes and hematocrit occurs with a simultaneous decrease in hemoglobin, and against the background of the development of hemorrhages, these indicators decrease, a decline in the values of MCH, MCHS and an increase in MCV are recorded. Regardless of the physiological state of the animal and changes in the area of the feet, the erythrocyte sedimentation rate (ESR) value and the level of leukocytes fluctuate within the limits of physiological values, which indicates the absence of an inflammatory process in the body. he revealed hematological changes indicate the development of adaptive processes in the event of hyperkeratosis and alopecia in the area of the plantar surface of the feet at various physiological conditions of rabbits with subsequent decompensating against the background of hemorrhagic changes.

Red blood cell counts in sows during lactation

Veterinarski glasnik ◽

10.2298/vetgl1006359j ◽

2010 ◽

Vol 64 (5-6) ◽

pp. 359-365 ◽

Cited By ~ 1

Author(s):

Mirjana Joksimovic-Todorovic ◽

Vesna Davidovic ◽

Ljiljana Bokan

Keyword(s):

Haemoglobin Concentration ◽

Lactation Period ◽

Mean Corpuscular Hemoglobin Concentration ◽

Corpuscular Hemoglobin ◽

The Third ◽

Cell Counts ◽

Erythrocyte Sedimentation ◽

In the course of parturition and lactation, sows are susceptible to stress and make an effort to adapt to the newly-formed situation through different endocrine and metabolic mechanisms. In addition to endocrine, biochemical changes, hematological changes also occur in the sow organism. Having these facts in mind, the objective of this work was to examine the changes in the number of erythrocytes, hemoglobin concentration, hematocrit value, hematological indexes: mean corpuscular erythrocyte volume (MCV), mean corpuscular hemoglobin (MCH) in erythrocyte and mean corpuscular hemoglobin concentration (MCHC) in erythrocytes, as well as sedimentation values during the period of lactation in sows. The experiment was performed on ten sows of the Swedish Landrace breed, from which blood was taken on the first day postpartum (1-6 h), and during the third and fourth weeks of lactation. The obtained results of hematological analyses indicated a reduced number of erythrocytes, haemoglobin concentration and hematocrit value during the lactation period. The number of erythrocytes was significantly lower at the end of lactation in comparison with the number established on the first day postpartum. The hemoglobin concentration and hematocrit value were very significantly lower at the end of lactation against the first day postpartum. The values of the hematological indexes MCV, MCH and MCHC did not differ significantly in any of the examined periods. The rate of erythrocyte sedimentation was determined 1 h and 2 h postpartum.

Hematological Changes Associated with Pregnancy in Domestic Sows (Suis domesticus)

Agricultural Science Digest - A Research Journal ◽

10.18805/ag.d-307 ◽

2021 ◽

Author(s):

Simeon C. Okafor ◽

Chinwe U. Chukwudi ◽

Kevin C. Okanya ◽

John I. Ihedioha

Keyword(s):

Blood Cell ◽

Absolute Lymphocyte Count ◽

Monocyte Count ◽

Corpuscular Hemoglobin ◽

Blood Samples ◽

The Mean ◽

The Absolute ◽

Background: Pregnancy involves complex biological interaction and communication between the developing conceptus and maternal uterus, which may alter the blood cellular elements. The present investigation evaluated the hematological changes associated with pregnancy in domestic sows. Methods: Blood samples were collected by auricular venipuncture from twenty sexually mature domestic sows from four pig farms. Hematological analyses were carried out on the blood samples following standard procedures. Result: The mean packed cell volume (PCV), the red blood cell (RBC) count, hemoglobin (Hb) concentration, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and absolute lymphocyte count were higher during pregnancy and lower following parturition, whereas, the mean corpuscular volume (MCV) was lower during pregnancy and declined further following parturition. The mean total white blood cell (TWBC) count and the absolute neutrophil count were higher during pregnancy and further elevated postpartum while the absolute monocyte count was lower during pregnancy and elevated postpartum. The absolute eosinophil count was significantly (p less than 0.05) lower in the pregnant sows (0.35 ± 0.13) and postpartum sows (0.21 ± 0.15) than in the non-pregnant sows (1.06 ± 0.27). These hematological alterations could assist in monitoring the physiological and health status of the dam, fetuses and pregnancy diagnosis.