scholarly journals Incidence of Dengue Infection among Febrile Patients in Port Sudan

2020 ◽  
pp. 1-6
Author(s):  
AreegSalih Abdel Aziz Ahmed ◽  
◽  
Tahani Bashir Mohammeddeen Ahmed ◽  
Keyword(s):  
Risk Factors ◽  
Dengue Fever ◽  
Clinical Symptoms ◽  
Venous Blood ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Occurrence Rate ◽  
Clinical Feature ◽  
Hematological Indicators

Objective: Aiming to detect dengue virus antibodies in clinically suspicious patients’ serum, contributing to clinical and laboratory advancements in dengue infection management, exploring the association between a clinico-laboratory makeup and Dengue fever, and enhancing the capacity to anticipate, diagnose, and respond to dengue infection. Methods: At Port Sudan 2015, a descriptive cross-sectional hospital-based study was implemented. Six tertiary care hospitals in Port Sudan were included in the report. Patients who attended assigned hospitals with a suspected dengue infection were investigated. Individuals who are at least 9 months old, residency in study area for at least 7 days, pyrexia with unspecified cause for 2-7 days, thrombocytopenia in malaria negative blood film, as well as ages of 9 months and older considerably involved. Gender, age, residency, and clinical symptoms were used as independent variables while dengue patients posing as the dependent variable. Sample size approximation was created based on previous African community studies. To target respondents, a randomized cluster model was used. Information was gathered through direct interview, as well as questionnaire after signed a consent form. 5ml of venous blood withdraw by a professional nurse from each respondent, then examined for hematological indicators of dengue fever using Sysmex XP-300 Automated Hematology Analyzerand dengue specific IgM antibodies using Panbio® Dengue IgM Capture ELISA. Entering data and analysis of the volunteers’ characteristics, the Statistical Package for Social Sciences program (SPSS Inc., Chicago, IL, USA) version 20 was used. Incredibly simple descriptive statistics were used to analyze the laboratory results of the Dengue indicators as well as risk factors. Results: The study involved 83 cases out of 110 that were tested by ELISA at different hospitals in Port Sudan and determined to be diagnosed with the dengue virus.The incidence rate among febrile patients was 75% (68 cases), with DF documented in 80 cases (96%) and DHF in three scenarios (4%). higher prevalence within the (21-30) age category 50/110. (45%).High occurrence rate during July (63 cases) (57%). Fever was the most noticeable clinical feature 79/83(95%, more evident hematological indicators included thrombocytopenia and leucopenia (88%) 97 out of 110 (71%) 78/110 in each event. Most of study subjects were unaware regarding risk factors with exception of transmission mode. Conclusions: Study reported high incidence among suspected febrile participants. Most of patients presented as DF, with greater occurrence among reproductive age group and during July.Thrombocytopenia and leucopenia were more prominent clinical manifestations.With the exception of the mode of transmission, the majority of study respondents were unaware of the risk factors.

scholarly journals Haematological profile of dengue fever

2017 ◽  
Vol 5 (12) ◽  
pp. 5367 ◽  
Author(s):  
Anita Tahlan ◽  
Amrita Bhattacharya
Keyword(s):  
Dengue Fever ◽  
Clinical Symptoms ◽  
Hematological Parameters ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Northern Region ◽  
Positive Serology ◽  
Community Based ◽  
Haematological Profile ◽  
Viral Illness

Background: Dengue is a viral illness that is increasingly becoming endemic in India. This study aimed to study the haematological profile of patients diagnosed with dengue infection in a tertiary care hospital.Methods: 89 patients suspected of having dengue illness were followed. Out of which those confirmed by positive serology were followed and studied in detail (n=46).Results: Common clinical symptoms were fever, vomiting, and abdominal pain. Common haematological abnormalities were thrombocytopenia and leucopoenia. All patients improved clinically with improvement of biochemical and hematological parameters. None of the patients died in this series.Conclusions: Dengue Fever continues to be a significant health problem especially in Northern region of India. A sharp vigilance is required by concerned authorities to prevent and minimize any future outbreak. It is extremely important to implement and maintain an effective, sustainable and community based disease prevention program.

scholarly journals Clinical profile of dengue fever in children: analysis of 2017 outbreak from Central Kerala, India

2018 ◽  
Vol 5 (6) ◽  
pp. 2265 ◽  
Author(s):  
Senthil Kumar K. ◽  
Rajendran N. K. ◽  
Ajith Brabhukumar C.
Keyword(s):  
Dengue Fever ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Hemorrhagic Fever ◽  
Warning Signs ◽  
Clinical Profile ◽  
Severe Dengue ◽  
High Morbidity ◽  
Care Hospital ◽  
High Grade Fever

Background: In India, dengue epidemics are becoming more frequent (WHO, 2008). The majority of dengue viral infections are self-limiting, but complications may cause high morbidity and mortality. The objective of this study is to assess the clinical profile of the dengue infection in children less than 15 years of age and to evaluate the outcomes of dengue fever from March 2017 to July 2017 at the Pediatric Department of Karuna Medical College, the tertiary care hospital in Palakkad.Methods: In this retrospective study, medical records were reviewed and analyzed. Patients with suspected dengue infection were classified further into 2 groups, Dengue fever (probable dengue, dengue with warning signs) and ‘Severe Dengue’ (dengue hemorrhagic fever and/or dengue shock syndrome (DHF/DSS) according to WHO.Results: A total of 77 cases were classified into 67 (87%) non-severe and 10 (13%) severe dengue cases. The most common age of presentation was above 10 yrs. The mean age of admission was 8.9 yrs. The most common presenting symptom was fever seen in 93% followed by vomiting in 68%. Elevation in Aspartate transaminase (SGOT) and thrombocytopenia were found in 32.4 %.Conclusions: High grade fever, vomiting, abdominal pain and skin rash with normal or low platelet count were the presenting features. Early diagnosis, monitoring and prompt supportive management can reduce mortality.

scholarly journals Clinicohaematological profile of dengue in children: a hospital based study

2017 ◽  
Vol 4 (4) ◽  
pp. 1340 ◽  
Author(s):  
Irshad Abdul Majeed ◽  
K. Shreedhara Avabratha ◽  
Lokesha R. Gowda ◽  
Sadia Syeda
Keyword(s):  
Dengue Fever ◽  
Early Recognition ◽  
Tertiary Care ◽  
Clinical Manifestations ◽  
Haematological Parameters ◽  
Severe Dengue ◽  
Clinical Feature ◽  
Igm Elisa ◽  
Ns1 Antigen ◽  
Atypical Presentations

Background: Dengue fever is one of the most common arbo virus mediated outbreaks, being reported from different parts of the world. Now as the outbreaks are hitting different geographic locations, different clinical manifestations are being reported recently. The aim of this study is to document varied clinical manifestations and haematological parameters of dengue patients in a tertiary care centre.Methods: A total 130 cases of any of NS1 antigen, IgM card test positive or IgM ELISA positive dengue patients were included in this observational study. Clinical and haematological parameters were noted and analysed statistically.Results: Most common clinical feature was fever (100%) followed by headache (51.5%). Atypical features like seizures due to encephalitis was seen in a child with dengue. Seizure were present in 1.5% of cases, two children died due to severe dengue with shock and multi organ failure. In our study 26.92% of patients had thrombocytopenia. The mean Hb was 12.86 g/dl and platelet count was 104202/mm3.Conclusions: Fever and headache are the main features of dengue. However, one should be aware of different atypical presentations of dengue fever to diagnose and intervene timely. Early recognition of complication and timely intervention are required in the management of dengue cases. 

scholarly journals TO STUDY THE DIFFERENT CLINICAL PRESENTATION OF MALARIA

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Saurabh Daseda ◽  
Gaurav Runwal
Keyword(s):  
Clinical Presentation ◽  
Clinical Symptoms ◽  
Tertiary Care ◽  
Clinical Malaria ◽  
Clinical Feature ◽  
Intermittent Fever ◽  
Tertiary Care Centre ◽  
Exclusion Criteria ◽  
Systemic Complication ◽  
Life Threatening

Method: This study was done at Department Of Medicine. All patients admitted with malaria in tertiary care Centre during the study period August 2017 to July 2018 were taken for the study after considering the inclusion and exclusion criteria. Our study is a clinical, prospective, observational and open study. Result: Fever occurred in all patients, and it was intermittent in 72.5% of the cases, continuous in 17.5% of the cases and remittent in the remaining 10%. Intermittent fever is the commonest. All 100% patients had chills and rigors. Most of the Patients (65%) had presented with acute illness of 2- 10 days duration of fever. Bifrontal dull aching to throbbing headache associated with fever was presenting clinical symptoms in 92% of patients. Most of the patients complained of generalized weakness, malaise and myalgia. Cerebral manifestation is seen in 10% of patients. Spleenomegaly was predominant in 64% of patients and 40% patient had hepatomegaly. Patient with mixed infection had more propensity to develop systemic complication. Conclusion: Malaria is an age-old disease of mankind, caused by protozoal plasmodium and transmitted by anopheles mosquito. It is prevalent throughout most tropical countries. Both species are commonly presented with symptoms of intermittent Fever, chills, Bi-frontal headache, vomiting and commonly clinical feature is splenomegaly. Severe complication like anemia, thrombocytopenia jaundice, acute renal failure and sometimes life threatening cerebral malaria are need to address promptly to avoid adverse outcome. Keywords: Clinical, Malaria, WHO & Presentation.

scholarly journals Clinical and laboratory profile and outcome of dengue cases among children attending a tertiary care hospital of South India

2017 ◽  
Vol 4 (3) ◽  
pp. 1074 ◽  
Author(s):  
Punith Patak Nagaram ◽  
Prathima Piduru ◽  
Venkata Krishna Munagala ◽  
Vishnu Vandana Matli
Keyword(s):  
Risk Factors ◽  
Dengue Fever ◽  
Bladder Wall ◽  
Tertiary Care ◽  
Severe Dengue ◽  
Wall Thickening ◽  
Severe Thrombocytopenia ◽  
Care Hospital ◽  
Age Group ◽  
Laboratory Profile

Background: Dengue fever is an arboviral disease which is endemic in tropical countries and is of major concern with its morbidity and mortality. WHO classified dengue into three categories: undifferentiated fever, dengue fever (DF) and dengue haemorrhagic fever (DHF). Severe dengue is also regularly observed during primary infection of infants born to dengue-immune mothers. The objective of present study was to assess the clinical profile, laboratory profile and associated risk factors related to outcome of children less than 15 years of age. The outcome of the children and their management protocols were also assessed in the study.Methods: A prospective cross sectional study with 174 confirmed cases of dengue in children <15 years were enrolled and classified as per WHO guidelines. The demographic data, clinical history, laboratory parameters were noted in a separate questionnaire form. Hematological parameters were noted, chest x-ray, ultra-sonogram in required cases was done and observations noted. Cases were managed as per WHO protocol and risk factors were observed. The outcomes of the cases were noted as discharge or death of the case.Results: A total of 174 children with 149 non-severe dengue and 25 severe dengue cases with 95 males and 79 females were enrolled in the study. 6-10 years was the most common age group. The mean age of children admitted with severe dengue fever was 5.81yrs.and without severe dengue fever was 7yrs.The mean duration of hospitalization was 5.21 days in severe dengue and 3.4 days in non-severe dengue cases. Fever was the most common presenting symptom and hepatomegaly was the common clinical finding in the study.  Bleeding manifestations were seen in cases of severe dengue with raised haematocrit levels, raised SGOT levels and severe thrombocytopenia. Pleural effusion and gall bladder wall thickening with ascites was seen in severe dengue cases. Management was by administration of colloids and crystalloids.Conclusions: Dengue is a dreadful fever among pediatric age group which needs to be considered with great caution in management.  Understanding the risk factors helps in predicting the mortality which helps in management and better outcome of the fever. 

scholarly journals FREQUENCY AND SEVERITY OF LIVER INVOLVEMENT IN DENGUE VIRUS INFECTION.

2019 ◽  
Vol 26 (07) ◽  
pp. 1074-1078
Author(s):  
Masood Tareen ◽  
Riaz Hussain Awan ◽  
Seema Nayab ◽  
Khadim Hussain Awan
Keyword(s):  
Dengue Fever ◽  
Liver Enzymes ◽  
Early Recognition ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Liver Involvement ◽  
Care Hospital ◽  
Cross Sectional ◽  
Study Setting

Objectives: To determine the frequency & severity of liver involvement in dengue infection among adults at tertiary care hospital. Period: Six months (9th May 2016 to 9th Nov 2016). Study Design:  Cross-sectional study. Setting: Department of Gastroenterology and Department of Medicine Liaquat National Hospital, Karachi. Patients and Methods: Results: A total of 343 patients with Dengue fever were selected to conduct this study with mean age of 34.67±9.09 years. Mean duration of the fever was 7.31±1.62 days. Mean duration of hospital stay of the patients came out to be 3.50+0.82 days. Severity of liver enzymes derangement was mild in 80 patients (23%), moderate in 246 (72%) & severe in 17(5%). Mortality was seen in 14% (47 patients) & 100% mortality was seen in dengue fever patients with severely deranged Liver enzymes. Conclusion: Dengue fever patients with deranged liver enzymes had statistically worse outcome thus can lead to early recognition of high risk cases.

scholarly journals A clinical study of ectopic pregnancy in a tertiary care hospital

2018 ◽  
Vol 7 (11) ◽  
pp. 4461
Author(s):  
Arati Behera ◽  
Ranjita Ghadei ◽  
Rudra Narayan Bal
Keyword(s):  
Risk Factors ◽  
Ectopic Pregnancy ◽  
Tertiary Care ◽  
Medical Practitioner ◽  
High Risk Group ◽  
Reproductive Age ◽  
Common Symptom ◽  
Care Hospital ◽  
Age Group ◽  
Future Fertility

Background: Ectopic pregnancy is a life-threatening emergency commonly encountered by medical practitioner. Diagnosis is frequently missed and should be considered in any women in the reproductive age group with abdominal pain or vaginal bleeding. The aim of the study is to assess the incidence, clinical presentation, risk factors, methods of diagnosis, treatment, outcome and complications.Methods: This was a prospective study at S.C.B. Medical college from January to December 2017. Parameters like age, parity, gestational period, risk factors, clinical presentations, findings on ultrasonogram and at surgery with morbidities associated with diagnosed cases of ectopic pregnancy (n=93) were noted and analysed with SPSS-19 software.Results: Incidence of ectopic pregnancy was 18/1000 deliveries. Maximum cases were in age group of 21 to 30 years (54.8 %) and parous (76.3%). Common risk factors were having history of abortions (46.2%), previous tubal sterilization (24.7%), having one or more caesarean section (17.2%) and h/o infertility (16.1%). Most common symptom was pain abdomen (96.8%). Commonest site was ampullo-isthmic region of tube and rupture was the commonest mode of presentation. All underwent laparotomy and unilateral salpingectomy was done in 86 % of cases. It contributed to 3.27 % of total maternal deaths.Conclusions: Suspicion in high risk group can direct one to investigate and diagnose early, thereby reducing morbidity, mortality and improving the prospect of future fertility.

scholarly journals FACTORS PREDICTING MORBIDITY IN PATIENTS WITH DENGUE FEVER IN A TERTIARY CARE HOSPITAL

2013 ◽  
Vol 5 (1) ◽  
pp. e2013014 ◽  
Author(s):  
Muhammad Imran Hasan Khan ◽  
Eram Anwar ◽  
Adnan Agha ◽  
Noha Saleh ◽  
Ehsan Ullah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dengue Fever ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
Denv Infection ◽  
Care Hospital ◽  
Factors Associated ◽  
Logistics Regression

Introduction: Dengue virus (DENV) affects over half the world’s population in 112 countries, and dengue fever (DF) is the second largest arthropod borne infectious global hazard after malaria with complications like Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) accounting for significant morbidity and mortality world over. Pakistan is significantly affected with DENV infection and to-date no study identifying risk factors associated with complications of DF has been done. Methods: 997 confirmed cases of DF were collected in a tertiary care hospital in Lahore, Pakistan and their clinical and biochemical data were collected. Univariate, multivariate and logistics regression analysis was performed to identify risk factors associated with development of DHF and DSS. Results: Bleeding OR 70.7 (CI 38.4-129.9), deranged liver function test OR 1.9 (CI 0.97-0.99), platelet count on admission less than 50,000 x109/L OR 0.16 (CI 0.13-0.19), presence of urinary red blood cells OR 1.4 (CI 0.179-0.900) and presence of urinary protein OR 1.1 (CI 0.191-0.974) were related to development of DHF and DSS.

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