Is ischemic modified albumin a marker in osteomyelitis patients?

2020 ◽  
pp. 1-13
Author(s):  
Cihan Adanas ◽  
Sezai Ozkan ◽  
Canan Demir
Keyword(s):  
Prospective Study ◽  
Key Words ◽  
Albumin Level ◽  
Healthy Controls ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Ischemia Modified Albumin ◽  
Protein Levels ◽  
Reactive Protein ◽  
The Cross

Abstract Objective: To compare the levels of ischemia modified albumin between osteomyelitis patients and healthy controls. Method: The cross-sectional prospective study was conducted at Van Yüzüncü Y?l University, Van, Turkey, from May 2018 to May 2019, and comprised inpatients diagnosed with osteomyelitis, and healthy controls. Serum IMA concentrations were determined spectrophotometrically at 470nm wavelength. Serum ischemia modified albumin levels were measured and compared between the patients and the controls. Data was analysed using SPSS 20. Results: Of the 77 subjects, 37(48%) were patients and 40(52%) were controls. Serum ischemia modified albumin level in patients was significantly higher than controls (p<0.05). There was a significant correlation between ischemia modified albumin and C-reactive protein levels (p<0.05). Conclusion: Serum ischemia modified albumin level in patients was significantly higher than controls (p<0.05). Key Words: Osteomiyelitis, Ischemia-modified albumin, Receiving operation curve, Biomarker, C-reactive protein. Continuous...

scholarly journals Use of C-reactive protein level in diagnosis of tubercular pleural effusion

2019 ◽  
Vol 8 (1) ◽  
pp. 20-23
Author(s):  
Subash Pant ◽  
Sanjeet Krishna Shrestha ◽  
Lucky Sharma ◽  
Bibechana Shrestha
Keyword(s):  
Pleural Effusion ◽  
Pleural Fluid ◽  
Protein Level ◽  
College Teaching ◽  
C Reactive Protein ◽  
Biochemical Tests ◽  
Cross Sectional ◽  
Female Ratio ◽  
Protein Levels ◽  
Reactive Protein

Background: C-reactive protein in both pleural fluid and serum has been found to be higher in tubercular pleural effusion than in other causes of pleural effusion. Objectives: The main aim of this study was to find out the diagnostic value of C-reactive protein in patients withlymphocytic pleural effusion. Methodology: A cross-sectional study was conducted in 90 patients with pleural effusion who underwent thoracocentesis at Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal. The complete biochemical tests of pleural fluid and serum were performed. The C-reactive protein concentrations of both pleural fluid and serum were then measured from samples from patients with lymphocytic exudative pleural effusion. Results: Ninety patients with exudative lymphocytic pleural effusion were included. Male patients were 56 (62.2%) and female were 34 (37.8%) with the male to female ratio of 1.64. Mean age of the patients was 51±21.54 (Mean ± Standard Deviation). The pleural fluid C-reactive protein levels in tubercular pleural effusion were higher (48.87±24.19 mg/dl) compared to non-tubercular group (38.30±17 mg/dl; p<0.001). Similarly, the serum fluid C-reactive protein levels in tubercular pleural effusion were higher (29.60±13mg/dl) compared to non-tubercular group (18.14±9.2mg/dl; p< 0.001). The sensitivity of pleural fluid C-reactive protein level in diagnosing tubercular pleural effusion was 86%. Conclusion: Simple and inexpensive test like C-reactive protein is useful in the diagnostic workup of lymphocytic pleural effusions. High C-reactive protein levels are very suggestive of tubercular pleural effusion.

C-reactive protein levels are related to suicidality in euthymic patients with bipolar disorder

2016 ◽  
Vol 33 (S1) ◽  
pp. S337-S337
Author(s):  
M. Pantovic Stefanovic ◽  
B. Dunjic-Kostic ◽  
M. Lackovic ◽  
A. Damjanovic ◽  
A. Jovanovic ◽  
...  
Keyword(s):  
Suicide Attempts ◽  
Previous History ◽  
Control Group ◽  
Healthy Controls ◽  
C Reactive Protein ◽  
Course Of Illness ◽  
Protein Levels ◽  
Reactive Protein ◽  
History Of ◽  
Competing Interest

IntroductionImmune alterations are believed to be an important part in etiopathogenesis of affective disorders. However, it is not clear if the altered immune mediators are related to distinct disorders or particular psychopathology.AimsThe aim of our study was to explore the differences in C-reactive protein levels (CRP) between euthymic BD patients and healthy controls, as well as to explore the relationship between CRP and lifetime presented psychopathology within BD.MethodsThe study group consisted of 83 patients diagnosed with BD, compared to the healthy control group (n = 73) and matched according to age, gender, and body mass index (BMI). Lifetime psychopathology has been assessed according to predominant polarity as well as previous history of suicide attempts and psychotic episodes.ResultsThe CRP levels were significantly higher in BD patients when compared to healthy controls. After covarying for confounders, we observed that CRP levels, in euthymic BD patients, were related to number of previous suicide attempts, but not other indicators of lifetime psychopathology.ConclusionsBD patients per se, and particularly those with more suicide attempts, are more likely to present with proinflammatory state, even when in remission. Previous history of suicide attempts could bear specifically vulnerable endophenotype within BD. Systemic, longitudinal monitoring of the course of illness, and potential inflammatory mediators that underlie its systemic nature is warranted.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Evaluation of Ischemia-Modified Albumin and C-Reactive Protein in Type 2 Diabetics with and without Ketosis

2012 ◽  
Vol 7 ◽  
pp. BMI.S9060 ◽  
Author(s):  
Shao-gang Ma ◽  
Yao Jin ◽  
Wen Hu ◽  
Feng Bai ◽  
Wen Xu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Patients ◽  
C Reactive Protein ◽  
Type 2 Diabetic Patients ◽  
Ischemia Modified Albumin ◽  
Protein Levels ◽  
Reactive Protein ◽  
Diabetic Ketosis ◽  
Type 2 Diabetics

Overview To investigate whether serum ischemia-modified albumin or C-reactive protein is reliable for predicting type 2 diabetic patients with ketosis. Approach One hundred and four diabetic patients, 48 with diabetic ketosis, and 33 controls were enrolled in the study. Serum ischemia-modified albumin and C-reactive protein were measured and evaluated for their ability to distinguish diabetic ketosis. Results Compared to the controls, the ischemia-modified albumin and C-reactive protein levels were higher in patients with diabetic ketosis and type 2 diabetes at the baseline. The levels of ischemia-modified albumin were higher in patients with type 2 diabetes than in the controls. C-reactive protein and ischemia-modified albumin levels were reduced after insulin treatment. The level of ischemia-modified albumin was an independent risk marker for diabetic ketosis ( OR = 1.085, P = 0.008, 95% CI: 1.022–1.152). Receiver operating characteristic curves revealed that the areas under the curve were 0.917 for the modified albumin and 0.357 for C-reactive protein. Conclusion This study indicates that ischemia-modified albumin was significantly associated with diabetic ketosis and was more sensitive than C-reactive protein in reflecting diabetic ketosis.

scholarly journals Acute Phase Response in Patients With Uncomplicated and Complicated Endoscopic Retrogradic Cholangiopancreaticography

HPB Surgery ◽  
1994 ◽  
Vol 8 (2) ◽  
pp. 129-131 ◽  
Author(s):  
Heikki Kiviniemi ◽  
Tatu Juvonen ◽  
Jyrki Mäkelä
Keyword(s):  
Prospective Study ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Response Curve ◽  
Serum Amylase ◽  
Phase Response ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Biliary Diseases

Acute phase response after endoscopic retrogradic cholangiopancreaticography (ERCP) was studied in 42 patients with suspected pancreatic or biliary diseases. In uncomplicated cases acute phase response determined by serum C-reactive protein levels was rare and did not parallel the serum amylase or lipase levels. In three of the these 42 patients, post-ERCP pancreatitis developed and CRP levels elevated sharply and paralleled the degree of pancreatitis. Six additional patients outside of this prospective study with post-ERCP-pancreatitis and daily CRP determinations were used to determine the CRP-response curve in post-ERCP pancreatitis.

SEVERE CHRONIC PERIODONTITIS AND C-REACTIVE PROTEIN LEVELS

2017 ◽  
Vol 6 (2) ◽  
pp. 1
Author(s):  
Johelle De Santana Passos Soares ◽  
Isaac Suzart Gomes-Filho ◽  
Julita Maria Freitas Coelho ◽  
Simone Seixas da Cruz ◽  
Luís Claúdio Lemos Correia ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Descriptive Analysis ◽  
Cross Sectional Study ◽  
Blood Collection ◽  
C Reactive Protein ◽  
Clinical Attachment Loss ◽  
Cross Sectional ◽  
Protein Levels ◽  
Reactive Protein ◽  
Significant Difference

This study aims to analyze the relationship between chronic periodontitis and C-reactive protein (CRP), taking certain associated factors into consideration. A cross-sectional study was conducted on a sample of 75 adults of both sexes. After the participants had been interviewed, they underwent physical and dental examinations and blood collection. CRP levels were evaluated by means of nephelometry. A periodontal clinical examination was conducted by trained examiners and the diagnosis of chronic periodontitis was established when at least 30% of the individual’s teeth presented clinical attachment loss ≥ 5 mm. The analysis procedures consisted of descriptive analysis and linear regression. The results showed that there was no statistically significant difference in CRP levels between the groups with and without periodontitis. The median CRP level in the group with periodontitis was 2.3 mg/l (25-75% interquartile range, IQR = 0.74-5.4) and in the group without periodontitis, 1.8 mg/l (25-75% IQR = 0.79-4.54) (p = 0.417). Log CRP was significantly correlated only with the individual’s body mass index (BMI). The main findings from this study indicate that there is no association between severe chronic periodontitis and CRP, and factors like BMI need to be analyzed carefully in studies on this topic.

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