scholarly journals Peculiarities of hormonal, macro- and microelemental status in wrestlers

2021 ◽  
Vol 11 (1) ◽  
pp. 11-18
Author(s):  
D. S. Korolev ◽  
M. V. Ivkina ◽  
A. N. Arkhangelskaya ◽  
K. G. Gurevich
Keyword(s):  
Vitamin D ◽  
Control Group ◽  
Hormonal Status ◽  
Sports Performance ◽  
Elisa Method ◽  
Sodium Calcium ◽  
Icp Ms ◽  
Active Training ◽  
Potassium Magnesium

Objective: to determine the content of hormones, as well as some macro- and microelements in athletes-wrestlers outside the period of competition and active training.Materials and methods: the study involved 66 athletes-wrestlers and 107 students involved in sports professionally. The level of hormones and vitamin D was determined by the ELISA method. To analyze the content of macro- and microelements, the subjects were cut off a lock of hair from the back of the head in an amount of at least 0.1 g. The studies were carried out on an ICP-MS Agilent 7900 mass spectrometer.Results: levels of cortisol, TSH and T4 are higher, and levels of testosterone, T3 and vitamin D are lower in athletes compared to the control group. An increase in the content of sodium, calcium, potassium, magnesium, cobalt and a decrease in iodine were revealed in fighters from those who were not involved in sports professionally.Conclusion: the data obtained indicate an imbalance in the work of the body’s endocrine systems and impaired adaptation to stress. It is known that the determination of the hormonal status is used to assess the adaptation, the revealed changes in the indicators of vitamin D, macro- and microelements, allow the study of these indicators in order to prevent the syndrome of overtraining of athletes, to maintain and improve sports performance.

scholarly journals Determination of the Antioxidant Parameters of Commonly Available Black Pine (Pinus Nigra J.f. Arnold)

2021 ◽  
Vol 50 (4) ◽  
pp. 1021-1028
Author(s):  
Nuran Cikcikoglu Yildirim ◽  
Esref Gezer ◽  
Numan Yildirim
Keyword(s):  
Superoxide Dismutase ◽  
Industrial Area ◽  
Pinus Nigra ◽  
Control Group ◽  
Enzymatic Antioxidants ◽  
Black Pine ◽  
Elisa Method ◽  
Glutathione S Transferase ◽  
Antioxidant Parameters

The antioxidant parameters of black pine (Pinus nigra J.F. Arnold) needles samples collected from different areas in the province of Diyarbakır, Turkey were studied. Black pine needles samples were collected from three different locations (Egil, Kosuyolu, and Diyarbakır industrial area) in the province of Diyarbakır in summer and winter seasons. The activity of enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione S-transferase (GST) and malondialdehyde (MDA) levels of the samples were determined by ELISA method. Results showed that SOD enzyme activities of the samples collected in summer from Kosuyolu and the industrial area decreased compared to the control group, but increased in the samples collected in winter from the same areas. When compared to the control group, it was observed that the MDA levels of the samples collected from Kosuyolu and the industrial area increased. Bangladesh J. Bot. 50(4): 1021-1028, 2021 (December)`

LABORATORY RESEARCH OF HORMONAL STATUS IN PREGNANT WOMEN WITH OBESITY

2019 ◽  
pp. 49-54
Author(s):  
O. P. Myalyuk ◽  
M. I. Marushchak ◽  
O. V. Shtrimaitis ◽  
O. I. Golyb ◽  
N. V. Pystovit
Keyword(s):  
Pregnant Women ◽  
Placental Lactogen ◽  
Laboratory Research ◽  
Control Group ◽  
Hormonal Status ◽  
Gestational Period ◽  
Excessive Body Weight ◽  
The Moment ◽  
Pregnancy Hormones

During the physiological course of pregnancy, hormones are in equilibrium, providing adequate implantation and placental placement, necessary for the further normal development of the fetus. The most significant changes concern hormone-estrogen fraction and progesterone in pregnant women. The purpose of the study was to identify and assess laboratory parameters of hormonal background in pregnant women with obesity. 60 pregnant women with constitutional obesity were examined from 2018 to 2019. The patients were divided into two subgroups: I subgroup - 30 patients whom we prepared for pregnancy and conducted the entire gestational period, II subgroup -30 pregnant women were examined and received the necessary therapeutic and preventive measures only from the moment of treatment. The control group was composed of 20 pregnant women with a physiological course of the gestational period. For the evaluation of hormonal status, the determination of estradiol (E), progesterone (PG), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), as well as the chorionic gonadotropin (HG) and placental lactogen (PL) was carried out. We found that obese pregnant women had a significant reduction in the level of these hormones compared to healthy pregnant women, so the choice of obstetric tactics in pregnant women with obesity should be carried out according to their values. In addition, the determination of hormone level disorders allows to predict the development of severe complications already in the I trimester to the appearance of the first clinical and laboratory symptoms. Despite the high risk of complications in pregnant women with excessive body weight, obesity is not a contraindication to pregnancy.

LABORATORY RESEARCH OF HORMONAL STATUS IN PREGNANT WOMEN WITH OBESITY

2019 ◽  
pp. 49-54
Author(s):  
O. P. Myalyuk ◽  
M. I. Marushchak ◽  
O. V. Shtrimaitis ◽  
O. I. Golyb ◽  
N. V. Pystovit
Keyword(s):  
Pregnant Women ◽  
Placental Lactogen ◽  
Laboratory Research ◽  
Control Group ◽  
Hormonal Status ◽  
Gestational Period ◽  
Excessive Body Weight ◽  
The Moment ◽  
Pregnancy Hormones

During the physiological course of pregnancy, hormones are in equilibrium, providing adequate implantation and placental placement, necessary for the further normal development of the fetus. The most significant changes concern hormone-estrogen fraction and progesterone in pregnant women. The purpose of the study was to identify and assess laboratory parameters of hormonal background in pregnant women with obesity. 60 pregnant women with constitutional obesity were examined from 2018 to 2019. The patients were divided into two subgroups: I subgroup - 30 patients whom we prepared for pregnancy and conducted the entire gestational period, II subgroup -30 pregnant women were examined and received the necessary therapeutic and preventive measures only from the moment of treatment. The control group was composed of 20 pregnant women with a physiological course of the gestational period. For the evaluation of hormonal status, the determination of estradiol (E), progesterone (PG), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), as well as the chorionic gonadotropin (HG) and placental lactogen (PL) was carried out. We found that obese pregnant women had a significant reduction in the level of these hormones compared to healthy pregnant women, so the choice of obstetric tactics in pregnant women with obesity should be carried out according to their values. In addition, the determination of hormone level disorders allows to predict the development of severe complications already in the I trimester to the appearance of the first clinical and laboratory symptoms. Despite the high risk of complications in pregnant women with excessive body weight, obesity is not a contraindication to pregnancy.

scholarly journals Determination of the Level of some Adipokines in Hypo-and Hyperthyroids Patients in Baghdad City

2017 ◽  
Vol 14 (4) ◽  
pp. 713-716
Author(s):  
Baghdad Science Journal
Keyword(s):  
Tumor Necrosis Factor ◽  
Interleukin 6 ◽  
Tumor Necrosis ◽  
Control Group ◽  
Elisa Method ◽  
Hyperthyroid Patients ◽  
Necrosis Factor

Determination of the level of adipokines (obestatin, vaspin, tumor necrosis factor-? and interleukin-6)in hypo-and hyperthyroid patients from Educational Baghdad Hospital in Baghdad City was investigated. Fifty patients with hypothyroidism and Fifty patients with hyperthyroidism were selected. A control group of thirty euthyroid persons was included. Blood was collected by vein puncture and serum was separated and stored at –20C. Adipokines (obestatin, vaspin, tumor necrosis factor-? and interleukin-6) were estimated using ELISA method. The findings show a significant (p

Vitamin D Treatment in Patients with Hashimoto’s Thyroiditis may Decrease the Development of Hypothyroidism

2016 ◽  
Vol 86 (1-2) ◽  
pp. 9-17 ◽  
Author(s):  
Bekir Ucan ◽  
Mustafa Sahin ◽  
Muyesser Sayki Arslan ◽  
Nujen Colak Bozkurt ◽  
Muhammed Kizilgul ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Hashimoto’S Thyroiditis ◽  
Healthy Control Group ◽  
Hashimoto's Thyroiditis ◽  
Control Group ◽  
Endocrine Society ◽  
Thyroid Autoantibody ◽  
Healthy Control ◽  
The Mean

Abstract.The relationship between Hashimoto’s thyroiditis and vitamin D has been demonstrated in several studies. The aim of the present study was to evaluate vitamin D concentrations in patients with Hashimoto’s thyroiditis, the effect of vitamin D therapy on the course of disease, and to determine changes in thyroid autoantibody status and cardiovascular risk after vitamin D therapy. We included 75 patients with Hashimoto’s thyroiditis and 43 healthy individuals. Vitamin D deficiency is defined as a 25-hydroxy vitamin D (25(OH)D3) concentration less than 20ng/mL. Vitamin D deficient patients were given 50.000 units of 25(OH)D3 weekly for eight weeks in accordance with the Endocrine Society guidelines. All evaluations were repeated after 2 months of treatment. Patients with Hashimoto’s thyroiditis had significantly lower vitamin D concentrations compared with the controls (9.37±0.69 ng/mL vs 11.95±1.01 ng/mL, p < 0.05, respectively). Thyroid autoantibodies were significantly decreased by vitamin D replacement treatment in patients with euthyroid Hashimoto’s thyroiditis. Also, HDL cholesterol concentrations improved in the euthyroid Hashimoto group after treatment. The mean free thyroxine (fT4) concentrations were 0.89±0.02 ng/dL in patients with Hashimoto’s thyroiditis and 1.07±0.03 ng/dL in the healthy control group (p < 0.001). The mean thyroid volumes were 7.71±0.44 mL in patients with Hashimoto’s thyroiditis and 5.46±0.63 mL in the healthy control group (p < 0.01). Vitamin D deficiency is frequent in Hashimoto’s thyroiditis and treatment of patients with this condition with Vitamin D may slow down the course of development of hypothyroidism and also decrease cardiovascular risks in these patients. Vitamin D measurement and replacement may be critical in these patients.

FRACTIONAL DETERMINATIONS OF URINARY 17-KETOSTEROIDS IN HYPEREMESIS GRAVIDARUM

1962 ◽  
Vol 41 (1) ◽  
pp. 123-128 ◽  
Author(s):  
Pentti A. Järvinen ◽  
Sykkö Pesonen ◽  
Pirkko Väänänen
Keyword(s):  
Hyperemesis Gravidarum ◽  
First Trimester ◽  
Control Group ◽  
Before And After ◽  
Daily Urine ◽  
First Trimester Of Pregnancy ◽  
The Difference

ABSTRACT The fractional determination of 17-ketosteroids in the daily urine was performed in nine cases of hyperemesis gravidarum and in four control cases, in the first trimester of pregnancy both before and after corticotrophin administration. The excretion of total 17-KS is similar in the two groups. Only in the hyperemesis group does the excretion of total 17-KS increase significantly after corticotrophin administration. The fractional determination reveals no difference between the two groups of patients with regard to the values of the fractions U (unidentified 17-KS), A (androsterone) and Rest (11-oxygenated 17-KS). The excretion of dehydroepiandrosterone is significantly higher in the hyperemesis group than in the control group. The excretion of androstanolone seems to be lower in the hyperemesis group than in the control group, but the difference is not statistically significant. The differences in the correlation between dehydroepiandrosterone and androstanolone in the two groups is significant. The high excretion of dehydroepiandrosterone and low excretion of androstanolone in cases of hyperemesis gravidarum is a sign of adrenal dysfunction.

Determination of clinical efficiency of deproteinized dialysate from blood of milk-fed calves after endoprosthetics in patients with ventral hernias

2020 ◽  
Vol 28 (3) ◽  
pp. 323-333
Author(s):  
Sergej V. Ivanov ◽  
Ilya S. Ivanov ◽  
Evgenij G. Obyedkov ◽  
Liliya P. Popova
Keyword(s):  
Abdominal Wall ◽  
Inflammatory Reaction ◽  
Inflammatory Process ◽  
Anterior Abdominal Wall ◽  
Dynamic Change ◽  
Main Group ◽  
Control Group ◽  
Surgical Department ◽  
Regeneration Stage

Aim. To study the influence of deproteinized dialysate from blood of milk-fed calves on the type of exudative discharge and dynamics of inflammatory reaction after hernia repair with plastics of the anterior abdominal wall with hernioendoprosthesis of polypropylene. Materials and Methods. The study involved 59 patients being on stationary treatment in the surgical department of Kursk Regional Clinical Hospital. Patients were hospitalized for the herniation of small or medium dimension. The patients were divided to two groups: the main (n=30) and control (n=29) groups. After endoprosthetics, the patients of the control group were given complex conservative treatment. The patients of the main group, besides standard treatment, were administered deproteinized dialysate from blood of milk-fed calves intravenously in drips 10 ml + 200 ml of 0.9% sodium chloride solution within 7 days. For cytological examination and determination of the type of cytograms, the traumatic discharge was collected and analyzed using the method of M.F. Kamaev and M.A. Palthsev. Results. Cytomorphometric examination was conducted on the third, fifth and seventh day after endoprosthetics with the aim of studying dynamic changes. Determination of cell composition and also of its changes characteristic of each studied period, was necessary for obtaining further information characterizing inflammatory process in the region of placement of the endoprosthesis. After endoprosthetics in patients who were administered hemodialysate, the inflammatory reaction was less pronounced than in patients who did not receive the preparation. This was associated with a more dynamic change of stages of the inflammatory process. In patients of the main group who received deproteinized dialysate, regenerative type of inflammation first appeared on the fifth day and made 6.9%; by the seventh day the share of patients with the regenerative type rose to 17.5%, while in the patients of the control group no regeneration stage was observed in both periods. Conclusion. Analysis of the efficiency of influence of hemodialysate on the inflammatory reaction in plastics of the anterior abdominal wall with polypropylene endoprosthesis evidences faster course of all stages of inflammation and reduction of its intensity by 10%.

Potential predictive marker of treatment effectiveness in patients with osteopenic syndrome after surgical menopause

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (4) ◽  
pp. 39-42
Author(s):  
Yansiiat Z. Zaydieva ◽  
Elena V. Kruchinina ◽  
Olga S. Gorenkova ◽  
Elena Yu. Polyakova ◽  
Elena N. Kareva ◽  
...  
Keyword(s):  
Vitamin D ◽  
Combination Therapy ◽  
Vitamin D Receptor ◽  
Surrogate Marker ◽  
Predictive Marker ◽  
Expression Level ◽  
Mineral Density ◽  
Vitamin D Receptors ◽  
Surgical Menopause

Introduction. Patients with surgical menopause have a risk for osteopenic syndrome (OS). Menopausal hormone therapy (MHT) in combination with calcium and vitamin D promotes increase in bone mineral density (BMD). The expression level of vitamin D receptor in mononuclear fraction cells (MNFC) of blood can be considered as a predictive marker of effectiveness of OS therapy. Aim. To search a molecular predictive marker of the effectiveness of OS treatment. Materials and methods. The study included 100 women aged 4055 years with a duration of surgical menopause from 12 months to 6 years. The criterion for including patients in the study was the absence of contraindications to the use of MHT. The subject of the study was the determination of BMD by dual-energy X-ray absorptiometry, polymerase chain reaction diagnostics of the level of expression of vitamin D genes, estradiol and progesterone receptors, determination of 25-OH vitamin D in the blood. Results. Analysis of 12-month OS therapy effectiveness evaluated with a surrogate marker BMD. The increase in BMD up to 34% per year was treated as absence of negative dynamics, more than 4% per year as positive one. Significant effect of combination therapy compared with MHT on BMD in patients with surgical menopause with a low baseline level of BMD (due to hypovitaminosis D) is associated with the anti-inflammatory, bone-protective effect of vitamin D. In both groups of patients not responding; to the prescribed therapy we were able to conduct a comparative analysis of expression level of the target molecules in the MNFC before the start of treatment. The efficacy of MHT and combination therapy for BMD disorders is positively associated with the expression level of vitamin D receptors in MNFC before treatment. Therefore, the vitDR mRNA level is a potential predictive marker of the effectiveness of OS treatment. The expression levels of nuclear estradiol beta receptor and membrane receptor for progesterone in MNFC before treatment showed an upward trend in women responding to therapy. Conclusion. The expression level of the vitamin D receptor in MNFC of blood is significantly lower in the group of women with no/insufficient effect on 12-month combined therapy. This indicator can be considered as a predictive marker of the effectiveness of OS therapy.

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