scholarly journals Verification of Internal Oleation Doses mentioned by Vangasena to achieve proper Oleation before Vamana and Virechana

2015 ◽  
Vol 6 (3) ◽  
Author(s):  
Vishakha Rajesh Wetal
Keyword(s):  
Maximum Dose ◽  
Objective Evaluation ◽  
Therapeutic Purpose ◽  
Time Required ◽  
Medium Dose

Background -Maximum(Pradhan), minimum(heena) and medium(madhyam) doses for  internal oleation pursued as preparation, before Vamana (induced vomiting for therapeutic purpose) and Virechana (induced purgation for therapeutic purpose) is mentioned in all three Ayurveda classic texts (Brihat-trayi), on the basis of time required for its digestion and doshavastha.. This method is very subjective contrary to the objective evaluation affirmed in Vangasen-Snehpanadhikar(VS), where evaluator does not make any judgment. The actual dose quantification, in increasing order for shodhan purpose is mentioned in VS. Objective-To verify suitability of internal oleation doses cited in Vangasen to achieve Samyak Snigdha Lakshanani(SSL) and to monitor its complications if any.    Method - This method was applied for 18 patients intended for either Vamana or Virechana to verify its authenticity to achieve SSL. Sixteen patients were given medium dose and two were given maximum dose. Oleation was discontinued as soon as SSL were achieved.Result-Out of 18 patients one achieved SSL in three days, five in four days, six in five days and five patients in six days. One patient took seven days to achieve SSL. Out of 18 patients, on last day one digest sneha in 2 hrs, 3 digest it in 4 to 5 hrs, 9 in 6 to 7 hrs, and 5 patients took 10 to 15 hrs to digest sneha on the day of completion of Snehana. Complications were not observed in any patient.Conclusion-Medium or maximum doses specified in VS, can be used for internal oleation before Vamana and Virechana to achieve SSL without any complication. Thus the method is practical one. 

scholarly journals Dose-volume histogram constrains for small intestine in postoperative transcutaneous radiotherapy of endometrial carcinoma: comparison between conventional and conformal techniques

2013 ◽  
Vol 3 (2) ◽  
pp. 82-87
Author(s):  
Anela Ramić ◽  
Dženita Ljuca ◽  
Goran Marosević
Keyword(s):  
Small Intestine ◽  
Maximum Dose ◽  
Three Dimensional ◽  
Conformal Radiotherapy ◽  
Dose Volume Histogram ◽  
Dose Volume ◽  
Clinical Center ◽  
The Difference ◽  
Paired T Test ◽  
Medium Dose

Introduction: The aim of this study was to determine the dose-volume histogram (DVH) constrains of conventional and conformal transcutaneous radiotherapy for small intestine and perform their comparison.Methods: This retrospective-prospective study included patients who were treated for endometrial cancer using conventional transcutaneous radiotherapy at the Department of Radiotherapy Clinic of Oncology,Hematology and Radiotherapy, University Clinical Center Tuzla in the period from 2009 to 2011. The study was performed on patients of all ages suffering from this condition. The study involved 35 patients. DVHparameters which were analyzed are: minimum dose (Dmin), maximum dose (Dmax), medium dose (Daver) of the small intestine, as well as the volume of the small intestine, which is included in 75%, 95% and 100%dose (V33,75Gy, V42,75Gy, V45Gy) expressed in percentages and cubic centimeters of the affected organ. Working hypothesis was tested with paired t test. The difference between the variables at the level of p <0.05 was considered statistically significant.Results: DVH constrains of transcutaneous conformal radiotherapy showed signifi cantly smaller dose contribution on small intestine than DVH parameters of conventional transcutaneous radiotherapy (p<0.0001).Conclusion: The dose contribution on small intestine was signifi cantly lower by planning three-dimensional conformal transcutaneous radiotherapy in comparison to the conventional planning.

scholarly journals Comparison of Turfgrass Visual Quality Ratings with Ratings Determined Using a Handheld Optical Sensor

2009 ◽  
Vol 19 (2) ◽  
pp. 309-316 ◽  
Author(s):  
Gregory E. Bell ◽  
Dennis L. Martin ◽  
Kyungjoon Koh ◽  
Holly R. Han
Keyword(s):  
Optical Sensor ◽  
Data Entry ◽  
Visual Quality ◽  
Objective Evaluation ◽  
Visual Evaluation ◽  
Growing Seasons ◽  
Human Evaluation ◽  
Quality Ratings ◽  
Turfgrass Quality ◽  
Time Required

Turfgrass performance can be assessed in terms of visual quality, but evaluators require training and may be distracted by many factors that affect accuracy and consistency. The objectives of this study were to assess a handheld optical sensor (GreenSeeker) for evaluating overall turfgrass quality in three turf species over two growing seasons, and to compare the combined time required for visual evaluation and data entry with the time required for the same functions using the handheld optical sensor. Visual quality ratings and sensor ratings were collected on schedules prescribed by the National Turfgrass Evaluation Program for the 2002 bermudagrass (Cynodon spp.), 2002 buffalograss (Buchloe dactyloides), and 2002 zoysiagrass (Zoysia spp.) studies in 2003 and 2004. Use of the sensor reduced the time required to complete data collection and data entry by 58% compared with human visual evaluation. Of the three species tested, the bermudagrass evaluation had the strongest correlation between ratings collected by the human evaluator and the sensor [r = 0.79 in 2003 (n = 343), r = 0.85 in 2004 (n = 343)]. The handheld optical sensor provided a consistent, objective evaluation of overall turfgrass quality and required less time than visual evaluation. The handheld optical sensor provides advantages for assessing turfgrass quality that cannot be realized by human evaluation, but the sensor alone is not sufficient for specific evaluations such as color, texture, or density that are routinely characterized by human evaluation.

The Critical Point Drying Method Applied to Scanning Electron Microscopy of L-929 Cells

1970 ◽  
Vol 28 ◽  
pp. 278-279
Author(s):  
Charles TurnbiLL ◽  
Delbert E. Philpott
Keyword(s):  
Electron Microscopy ◽  
Carbon Dioxide ◽  
Surface Tension ◽  
Critical Point ◽  
Freeze Drying ◽  
Attractive Alternative ◽  
Crystal Formation ◽  
Critical Point Drying ◽  
Time Required ◽  
Scanning Electron

The advent of the scanning electron microscope (SCEM) has renewed interest in preparing specimens by avoiding the forces of surface tension. The present method of freeze drying by Boyde and Barger (1969) and Small and Marszalek (1969) does prevent surface tension but ice crystal formation and time required for pumping out the specimen to dryness has discouraged us. We believe an attractive alternative to freeze drying is the critical point method originated by Anderson (1951; for electron microscopy. He avoided surface tension effects during drying by first exchanging the specimen water with alcohol, amy L acetate and then with carbon dioxide. He then selected a specific temperature (36.5°C) and pressure (72 Atm.) at which carbon dioxide would pass from the liquid to the gaseous phase without the effect of surface tension This combination of temperature and, pressure is known as the "critical point" of the Liquid.

Radiation Damage of Support Films

1981 ◽  
Vol 39 ◽  
pp. 28-29
Author(s):  
H.A. Cohen ◽  
W. Chiu
Keyword(s):  
Transfer Function ◽  
Low Temperatures ◽  
Carbon Support ◽  
Contrast Transfer Function ◽  
Electron Dose ◽  
Imaging Parameters ◽  
Negative Stain ◽  
Phase Corrections ◽  
Two Parameters ◽  
Medium Dose

The goal of imaging the finest detail possible in biological specimens leads to contradictory requirements for the choice of an electron dose. The dose should be as low as possible to minimize object damage, yet as high as possible to optimize image statistics. For specimens that are protected by low temperatures or for which the low resolution associated with negative stain is acceptable, the first condition may be partially relaxed, allowing the use of (for example) 6 to 10 e/Å2. However, this medium dose is marginal for obtaining the contrast transfer function (CTF) of the microscope, which is necessary to allow phase corrections to the image. We have explored two parameters that affect the CTF under medium dose conditions.Figure 1 displays the CTF for carbon (C, row 1) and triafol plus carbon (T+C, row 2). For any column, the images to which the CTF correspond were from a carbon covered hole (C) and the adjacent triafol plus carbon support film (T+C), both recorded on the same micrograph; therefore the imaging parameters of defocus, illumination angle, and electron statistics were identical.

Search mode for rapid detection of virus particles

1991 ◽  
Vol 49 ◽  
pp. 286-287
Author(s):  
O. E. Bradfute
Keyword(s):  
Electron Microscopy ◽  
Rapid Detection ◽  
Plant Virus ◽  
Low Dose ◽  
Search Mode ◽  
Virus Diseases ◽  
Virus Particles ◽  
Focus Image ◽  
Time Required ◽  
Rapid Switching

Electron microscopy is frequently used in preliminary diagnosis of plant virus diseases by surveying negatively stained preparations of crude extracts of leaf samples. A major limitation of this method is the time required to survey grids when the concentration of virus particles (VPs) is low. A rapid survey of grids for VPs is reported here; the method employs a low magnification, out-of-focus Search Mode similar to that used for low dose electron microscopy of radiation sensitive specimens. A higher magnification, in-focus Confirm Mode is used to photograph or confirm the detection of VPs. Setting up the Search Mode by obtaining an out-of-focus image of the specimen in diffraction (K. H. Downing and W. Chiu, private communications) and pre-aligning the image in Search Mode with the image in Confirm Mode facilitates rapid switching between Modes.

Microwaves: Application in Electron Microscopy

1990 ◽  
Vol 48 (3) ◽  
pp. 140-141
Author(s):  
Anthony S-Y Leong ◽  
David W Gove
Keyword(s):  
Electron Microscopy ◽  
Light Microscopy ◽  
Chemical Reactions ◽  
Electromagnetic Waves ◽  
Tissue Fixation ◽  
Primary Method ◽  
Dipolar Molecules ◽  
Wide Range ◽  
Time Required ◽  
Cryostat Sections

Microwaves (MW) are electromagnetic waves which are commonly generated at a frequency of 2.45 GHz. When dipolar molecules such as water, the polar side chains of proteins and other molecules with an uneven distribution of electrical charge are exposed to such non-ionizing radiation, they oscillate through 180° at a rate of 2,450 million cycles/s. This rapid kinetic movement results in accelerated chemical reactions and produces instantaneous heat. MWs have recently been applied to a wide range of procedures for light microscopy. MWs generated by domestic ovens have been used as a primary method of tissue fixation, it has been applied to the various stages of tissue processing as well as to a wide variety of staining procedures. This use of MWs has not only resulted in drastic reductions in the time required for tissue fixation, processing and staining, but have also produced better cytologic images in cryostat sections, and more importantly, have resulted in better preservation of cellular antigens.

Projected Structure of the Surface Protein of Sulfolobus Spec. B12 Determined to a Resolution of 1.0 NM by Cryo-Electronmicroscopy

1990 ◽  
Vol 48 (1) ◽  
pp. 102-103
Author(s):  
G. Lembcke ◽  
F. Zemlin
Keyword(s):  
Low Dose ◽  
Maximum Dose ◽  
Three Dimensional ◽  
Surface Protein ◽  
Protein S ◽  
Radiation Sensitivity ◽  
Specimen Preparation ◽  
Molecular Architecture ◽  
High Radiation ◽  
Fritz Haber

The thermoacidophilic archaebacterium Sulfolobus spec. B12 , which is closely related to Sulfolobus solfataricus , possesses a regularly arrayed surface protein (S-layer), which is linked to the plasma membrane via spacer elements spanning a distinct interspace of approximately 18 nm. The S-layer has p3-Symmetry and a lattice constant of 21 nm; three-dimensional reconstructions of negatively stained fragments yield a layer thickness of approximately 6-7 nm.For analysing the molecular architecture of Sulfolobus surface protein in greater detail we use aurothioglucose(ATG)-embedding for specimen preparation. Like glucose, ATG, is supposed to mimic the effect of water, but has the advantage of being less volatile. ATG has advantages over glucose when working with specimens composed exclusively of protein because of its higher density of 2.92 g cm-3. Because of its high radiation sensitivity electromicrographs has to be recorded under strict low-dose conditions. We have recorded electromicrographs with a liquid helium-cooled superconducting electron microscope (the socalled SULEIKA at the Fritz-Haber-lnstitut) with a specimen temperature of 4.5 K and with a maximum dose of 2000 e nm-2 avoiding any pre-irradiation of the specimen.

Clinical Update: Functional Capacity Evaluations—An Update

1999 ◽  
Vol 4 (5) ◽  
pp. 4-7 ◽  
Author(s):  
Laura Welch
Keyword(s):  
Job Performance ◽  
Functional Capacity ◽  
Injury Risk ◽  
Disability Evaluation ◽  
Time Period ◽  
Submaximal Effort ◽  
Lack Of Sleep ◽  
Overall Performance ◽  
Time Required ◽  
Specific Limitation

Abstract Functional capacity evaluations (FCEs) have become an important component of disability evaluation during the past 10 years to assess an individual's ability to perform the essential or specific functions of a job, both preplacement and during rehabilitation. Evaluating both job performance and physical ability is a complex assessment, and some practitioners are not yet certain that an FCE can achieve these goals. An FCE is useful only if it predicts job performance, and factors that should be assessed include overall performance; consistency of performance across similar areas of the FCE; consistency between observed behaviors during the FCE and limitations or abilities reported by the worker; objective changes (eg, blood pressure and pulse) that are appropriate relative to performance; external factors (illness, lack of sleep, or medication); and a coefficient of variation that can be measured and assessed. FCEs can identify specific movement patterns or weaknesses; measure improvement during rehabilitation; identify a specific limitation that is amenable to accommodation; and identify a worker who appears to be providing a submaximal effort. FCEs are less reliable at predicting injury risk; they cannot tell us much about endurance over a time period longer than the time required for the FCE; and the FCE may measure simple muscular functions when the job requires more complex ones.

Das rupturierte infrarenale Aortenaneurysma – eine kritische Analyse

VASA ◽  
1999 ◽  
Vol 28 (1) ◽  
pp. 30-33 ◽  
Author(s):  
Bürger ◽  
Meyer ◽  
Tautenhahn ◽  
Halloul
Keyword(s):  
Aortic Aneurysm ◽  
Aortic Rupture ◽  
Anesthetic Management ◽  
Objective Evaluation ◽  
Left Ventricular ◽  
Apache Ii ◽  
Apache Ii Score ◽  
Infrarenal Aortic Aneurysm ◽  
Emergency Situations ◽  
Probability Of Death

Background: Objective evaluation of the management of patients with ruptured infrarenal aortic aneurysm in emergency situations has been described rarely. Patients and methods: Fifty-two consecutive patients with ruptured infrarenal aortic aneurysm (mean age, 70.3 years; range, 56–89 years; SD 7.8) were admitted between January 1993 and March 1998. Emergency protocols, final reports, and follow-up data were analyzed retrospectively. APACHE II scores at admission and fifth postoperative day were assessed. Results: The time between the appearance of first symptoms and the referral of patients to the hospital was more than 5 hours in 37 patients (71%). Thirty-eight patients (71%) had signs of shock at time of admission. Ultrasound was performed in 81% of patients as the first diagnostic procedure. The most frequent site of aortic rupture was the left retroperitoneum (87%). Intraoperatively, acute left ventricular failure occurred in four patients, and cardiac arrest in two others. The postoperative course was complicated significantly in 34 patients. The overall mortality rate was 36.5% (n = 19). In 35 patients, APACHE II score was assessed, showing a probability of death of more than 40% in five patients and lower than 30% in 17 others. No patient showing probability of death of above 75% at the fifth postoperative day survived (n = 7). Conclusions: Ruptured aortic aneurysm demands surgical intervention. Clinical outcome is also influenced by preclinical and anesthetic management. The severity of disease as well as the patient’s prognosis can be approximated using APACHE II score. Treatment results of heterogenous patient groups can be compared.

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