Calciphylaxis in Renal Hyperparathyroidism: A Case-based Review

2016 ◽  
Vol 8 (2) ◽  
pp. 156-159
Author(s):  
Rajeev Parameswaran ◽  
Sandra Tan ◽  
Ngiam K Yuan ◽  
Diana GZ Lim
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
High Mortality ◽  
Severe Pain ◽  
Lower Extremities ◽  
The Body ◽  
Renal Hyperparathyroidism ◽  
Case Based

ABSTRACT Calciphylaxis is a rare fatal condition associated with chronic renal failure, with a prevalence of about 4%. The condition is associated with microcalcification of small- and medium-sized arteries, leading to skin ischemia, necrosis, and gangrene. Any part of the body may be involved, but it is predominant in the lower extremities. Severe pain is usually associated with ulcers and may be difficult to manage. Although parathyroidectomy may improve the symptoms, the prognosis remains dismal with a high mortality. We present a case of severe calciphylaxis associated with renal hyperparathyroidism and briefly review the literature on the condition. How to cite this article Tan S, Yuan NK, Lim DGZ, Parameswaran R. Calciphylaxis in Renal Hyperparathyroidism: A Case-based Review. World J Endoc Surg 2016;8(2):156-159.

scholarly journals Expected ages in the patients of chronic diseases

2016 ◽  
Vol 10 (4) ◽  
Author(s):  
Intesaruk Rashid Khan ◽  
Ahmed Imran Siddiqui ◽  
Wafa Aftab
Keyword(s):  
Heart Failure ◽  
Renal Failure ◽  
Retrospective Study ◽  
Chronic Disease ◽  
Chronic Renal Failure ◽  
Hepatic Cirrhosis ◽  
Disease Process ◽  
Chronic Illnesses ◽  
The Body ◽  
Medical Wards

This retrospective study was conducted to find out the expected ages in the patients of hepatic cirrhosis, chronic renal failure and heart failure. This study thus covers most of the patients of out medical wards presenting with chronic illnesses. On comparison of these expected ages it is also found that the expected age in all these three groups is not much different. So, the disease process or the mechanism of the chronic disease in the body may be different, but somehow the final out come is not much different in terms of life span.

scholarly journals Subtotal Parathyroidectomy: A Possible Treatment for Calciphylaxis

2003 ◽  
Vol 82 (5) ◽  
pp. 390-393 ◽  
Author(s):  
Gideon Bahar ◽  
Daniel Mimouni ◽  
Meora Feinmesser ◽  
Michael David ◽  
Aharon Popovzer ◽  
...  
Keyword(s):  
Renal Failure ◽  
Parathyroid Hormone ◽  
Chronic Renal Failure ◽  
Treatment Options ◽  
Lower Extremities ◽  
Skin Lesions ◽  
Rare Disorder ◽  
Subtotal Parathyroidectomy ◽  
Hormone Levels

Calciphylaxis is a rare disorder in patients with chronic renal failure that is characterized by ischemic necrotic skin lesions. The prognosis is grave and mortality is high (80%). The precise mechanism of calciphylaxis is still unknown, but in addition to chronic renal failure, elevated parathyroid hormone levels appear to play a role. The role of parathyroidectomy in treating affected patients is questionable. In this article, we describe the case of a patient with chronic renal failure who developed rapidly progressive subcutaneous calcifications and ulcerations in the lower extremities. These lesions regressed following subtotal parathyroidectomy. We also review the literature on calciphylaxis, with a focus on treatment options.

scholarly journals Etiology and outcome of peritoneal dialysis in 100 patients with chronic renal failure in Al-Ramadi Teaching

2020 ◽  
Vol 7 (2) ◽  
pp. 41-48
Author(s):  
Haitham N. AL-Koubaisy
Keyword(s):  
Renal Failure ◽  
Peritoneal Dialysis ◽  
Chronic Renal Failure ◽  
Teaching Hospital ◽  
Obstructive Uropathy ◽  
The Body ◽  
Common Disease ◽  
Human Beings ◽  
Significant Difference ◽  
Common Causes

Chronic renal failure is fatal disease because it leads to failure of excretory ,metabolic and endocrine functions of the kidneys which lead to disturb all physiological functions of the body some of these derangements is fatal to human beings to save human these body disturbances by chronic renal failure is treated by renal transplant and dialysis in different ways including peritoneal dialysis (PD.). Chronic renal failure is a common disease in patients attending Ramadi teaching hospital whom treated by peritoneal dialysis (PD) with variable results . So this study is introduced to detect the health status for managing chronic renal failure treated by peritoneal dialysis. All patients were 100 patients (53 male and 47 female) with CRF who admitted to the medical word in Al-Ramadi teaching hospital during a period from November 2008 till July 2009. Thorough history, examination and investigations were done for them including: hemoglobin, ESR ,blood urea, serum creatinine, ECG and abdominal U/S then PD was done for them according to their indications. The study showed that male was 53% with the age between 13 and 87 years while the female was 47% with the age between 12 and 91 years. Diabetes mellitus (DM) and hypertension (HT) were the most common cause of CRF. The outcome was: 30%complete improvement, 21% partial improvement, 26% less responsive and 23% died. In the last months of my study there was significant improvement. Inconclusion; DM and HT were the most common causes of CRF respectively; however obstructive uropathy had a notable ratio. There was no significant difference regarding sex. The outcome of PD was poor early in my study with significant improvements later.

scholarly journals GRANTING OF EDUCATION STRUCTURED NUTRITION AND ELECTROLYTE (ESNE) ON CHANGING INTERDIALYTIC WEIGHT GAIN IN CHRONIC CALCULATION FAILURE PATIENTS

2019 ◽  
Vol 3 (2) ◽  
pp. 89-99
Author(s):  
Lutfi Wahyuni ◽  
Ika Ainur Rofiah ◽  
Mochammad Achwandi
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Failure ◽  
Weight Gain ◽  
Chronic Renal Failure ◽  
Kidney Disease ◽  
Kidney Function ◽  
The Body ◽  
Artificial Kidney ◽  
Fluid Restriction ◽  
Interdialytic Weight Gain

ABSTRACT   GRANTING OF EDUCATION STRUCTURED NUTRITION AND ELECTROLYTE (ESNE) ON CHANGING INTERDIALYTIC WEIGHT GAIN IN CHRONIC CALCULATION FAILURE PATIENTS By Lutfi Wahyuni, Ika Ainur rofiah, Mochammad Achwandi Chronic kidney disease is a condition when kidney function begins to decline gradually. The condition of the decline in kidney function occurs due to many factors, one of which is because the kidney damage that has occurred intensely for many years. Patients with chronic renal failure need a management or hemodialysis therapy, which is the cleansing process of blood from waste substances, through a screening process outside the body using an artificial kidney in the form of a dialysis machine. Hemodialysis therapy is needed in the management of patients with chronic renal failure who cannot be treated again (terminal). The success of hemodialysis is based on various elements, one of which is compliance with fluid restrictions. Limitation of fluid intake in patients with chronic renal failure is very important. The provision of structured education can be given to patients with chronic kidney failure who are undergoing hemodialysis therapy. Education structured nutrition and electrolyte (ESNE) is a structured health education on nutrition and electrolyte management for chronic renal failure patients undergoing hemodialysis. ESNE is done to improve patients' understanding of diet and electrolyte compliance to prevent an increase in IDWG and to improve patient compliance with fluid restrictions. The stages of service activities that have been carried out are to explain fluid requirements and fluid restriction in patients with chronic renal failure using the Education structured nutrition and electrolyte (ESNE) method, the next recourse is an evaluation after continuous or ESNE administration of respondents given treatment and respondents who were not treated. Keywords: Diet, Chronic Kidney Disease, Hemodialysis 

scholarly journals Monitoring Nilai Kritis Tekanan Sistolik Dan Diastolik Pada Asuhan Keperawatan Gagal Ginjal Kronik Yang Dilakukan Hemodialisis Jenis Arteriovena Shunt Cimino Dan Akses Femoral Cephalica

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Martono Martono
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Design Research ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
The Body ◽  
Dialysis Access ◽  
Cross Sectional ◽  
Femoral Access ◽  
Av Shunt

Abstract: Systolic Pressure, Diastolic, Hemodialysis. Renal function at a more serious stage of the remnants of the metabolism could not be removed from the body, besides that, however, the kidneys can no longer change K / H for Na that resulted in an increase in the amount of potassium that machine that later can be triggered the interruption the heart. Hemodialysis is one of the alternative solutions that can be done when the kidneys experiencing the inability to mengekresikan debris from the remnants of the metabolism of the body. This research aims to clarify the picture changes critical value systolic pressure and diastolic pressure that done arteriovenous Cimino shunt type of hemodialysis and femoral access cephalic nursing nursery on chronic renal failure. This is the explanatory research design research with cross-sectional approach. A sample of this research is to patients with chronic renal failure undergoing hemodialysis which numbered 44 samples with sampling techniques using purposive sampling. This research statistics tests using descriptive test with the level of the significance of 95 %. The results of the study showed that the patients who performed hemodialysis aged candidates are age ≥51 about 59 percent and the age of the youngest 29 years and oldest 77 years, which dominated gender male.57 percent patients who do good hemodialysis AV Shunt or dialysis access Cephalica Femoral most no change in systolic pressure and diastolic pressure or settled.

scholarly journals Efektivitas Relaksasi Benson Terhadap Kecemasan Pasien Yang Menjalani Hemodialisa

2021 ◽  
Vol 14 (1) ◽  
pp. 57-64
Author(s):  
Isnaini Nur Anisah ◽  
Arina Maliya
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Literature Review ◽  
Kidney Function ◽  
Therapeutic Option ◽  
Hemodialysis Patients ◽  
The Body ◽  
Electrolyte Balance ◽  
Long Time ◽  
Body Fluid Balance

Pendahuluan: Penyakit gagal ginjal merupakan gangguan fungsi ginjal yang terjadi saat tubuh tidak bisa mempertahankan metabolisme, keseimbangan cairan serta elektrolit sehingga menyebabkan terjadinya retensi urea dan sampah nitrogen dalam darah. Hemodialisa menjadi pilihan terapi untuk mengatasi gagal ginjal kronik. Hemodialisa dilakukan dengan alat khusus untuk mempertahankan fungsi ginjal dengan menyeimbangkan kadar elektrolit dan keseimbangan cairan tubuh. Hemodialisa yang dilakukan dalam waktu lama dapat menyebabkan gangguan pada aspek biologis maupun aspek psikologis bagi pasien hemodialisa. Sebanyak 48,6 % pasien hemodialisa mengalami gangguan kecemasan. Salah satu non-farmakologi terapi untuk mengurangi kecemasan yaitu relaksasi benson yang dilakukan selama 15-20 menit setiap pagi dan sore hari. Tujuan dari penelitian untuk mengetahui efektivitas relaksasi benson terhadap kecemasan pada pasien yang menjalani hemodialisa. Metode yang digunakan untuk penelitian ini adalah studi literature review dengan membandingkan beberapa literature dari penelusuran situs jurnal seperti Sciendirect, PubMed, Elsevier dan Google Schoolar Hasil Penelitian menunjukkan relaksasi benson yang dilakukan sehari 2 kali selama 15-20 menit efektif untuk mengatasi masalah kecemasan pada pasien yang melakukan hemodialiasa. Kesimpulan: relakasi benson efektif dan bekerja dengan baik dalam menurunkan kadar kecemasan pada pasien hemodialisa Kata Kunci : gagal ginjal kronik, Hemodialisa, Cemas, Relaksasi Benson. Abstract: Introduction: Kidney failure is a disorder of kidney function that occurs when the body cannot maintain metabolism, fluid and electrolyte balance, causing retention of urea and nitrogen waste in the blood. Hemodialysis is a therapeutic option for treating chronic renal failure. Hemodialysis is performed with special tools to maintain kidney function by balancing electrolyte levels and body fluid balance. Hemodialysis that is carried out for a long time can cause disturbances in biological and psychological aspects for hemodialysis patients. As many as 48.6% of hemodialysis patients experienced anxiety disorders. One of the non-pharmacological therapies to reduce anxiety is benson relaxation which is done for 15-20 minutes every morning and evening. The aim of this study was to determine the effectiveness of Benson relaxation on anxiety in patients undergoing hemodialysis. The method used for this research is a literature review study by comparing some literature from searching journal sites such as Sciendirect, PubMed, Elsevier and Google Schoolar. The results showed that Benson relaxation which is carried out twice a day for 15-20 minutes is effective in overcoming anxiety problems in patients with do regular hemodialysis. Conclusion: Benson Relaxation is effective and works well in reducing anxiety levels in hemodialysis patients Keywords: chronic renal failure, hemodialysis, anxiety, Benson Relaxation

scholarly journals PENGARUH MUSIK INSTRUMENTAL TERHADAP KUALITAS HIDUP PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISA

2021 ◽  
Vol 4 (1) ◽  
pp. 125-134
Author(s):  
Tiarnida Nababan
Keyword(s):  
Quality Of Life ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Kidney Failure ◽  
Instrumental Music ◽  
Alternative Therapy ◽  
The Body ◽  
Wilcoxon Test ◽  
Rank Test

Chronic renal failure or late-stage renal disease is a progressive and irreversible disorder of renal function (the body fails in maintaining metabolism and balance of fluids and electrolytes), thereby causing uremia (retention of urea and other nitrogen waste in the blood). Treatment of kidney failure disease can be done by pharmacological and non-pharmacological means. Non-pharmacological treatment can be in the form of the provision of instrumental music. This study aims to find out the influence of instrumental music on quality of life in chronic kidney failure patients undergoing hemodialysis at the Royal Prima Hospital Medan. This type of research is pre-experimental research with a one-group pre-post-test design with the provision of instrumental music for 20 minutes. The population is 66 people and sampled as many as 20 people with accidental sampling techniques. The analysis used in using Wilcoxon test. Based on the calculation of the Wilcoxon signed-rank test, obtained Z= - 3,938 with (p=0.000) < 0.05, so it can be concluded that there is an instrumental music influence on the quality of life in chronic renal failure patients undergoing hemodialysis at Royal Prima Medan Hospital in 2018. It is recommended that instrumental music can be applied as an alternative therapy to improve the quality of life.

scholarly journals Assessment of pain in chronic renal failure patients going through hemodialysis

Rev Rene ◽  
2020 ◽  
Vol 21 ◽  
pp. e43685
Author(s):  
Fabiana Larissa Barbosa da Silva ◽  
Geórgia Alcântara Alencar Melo ◽  
Regilane Cordeiro dos Santos ◽  
Renan Alves Silva ◽  
Letícia Lima Aguiar ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Family Income ◽  
Pain Scale ◽  
The Body ◽  
Mcgill Pain Questionnaire ◽  
Visual Analogue Pain Scale ◽  
Cross Sectional ◽  
Income Source ◽  
Visual Analogue Pain

Objective: to assess the pain and the differences of this assessment with social, economic and clinical variables in individuals with chronic kidney disease. Methods: cross-sectional study, with 90 patients with hemodialysis clinics. Three instruments were used clinical/sociodemographic, visual analogue pain scale and McGill pain questionnaire. Mann-Whitney and Kruskal-Wallis U tests were used. Results: the most frequent kind of pain was musculoskeletal (35.6%), which was classified as moderate by using the visual analogue pain scale. In McGill’s questionnaire, the most selected categories were sensory and affective, which characterize pain as acute and thin. Significant statistical differences in medians of pain were found with family income, source of income, use of analgesics/anti-inflammatories, use of acupuncture and impaired sleep. Conclusion: pain was a recurrent result in various regions of the body among patients with chronic renal failure.

Новые подходы к лечению анемии хронических заболеваний

2018 ◽  
pp. 106-112
Author(s):  
А.В. Будневский ◽  
Е.С. Овсянников ◽  
Е.В. Воронина ◽  
Н.Б. Лабжания ◽  
Ю.Г. Жусина
Keyword(s):  
Renal Failure ◽  
Chronic Disease ◽  
Chronic Renal Failure ◽  
Lupus Erythematosus ◽  
Genetic Defect ◽  
The Body ◽  
Recombinant Erythropoietin ◽  
Anemia Of Chronic Disease ◽  
Downstream Signaling ◽  
Erythropoietin Treatment

Цель обзора - представление новых, патогенетически обоснованных подходов к лечению анемии хронических заболеваний. Анемия хронических заболеваний часто сопутствует многим хроническим инфекциям (инфекционный эндокардит, остеомиелит, туберкулез), злокачественным новообразованиям, ревматическим болезням (ревматоидный артрит, системная красная волчанка, васкулиты), хронической почечной недостаточности. Генез такой анемии довольно сложен, многообразен и недостаточно изучен. Гепсидин является важнейшим пептидом, регулирующим всасывание железа в кишечнике. Множество восходящих и нисходящих сигнальных путей контролируют эксперссию гепсидина. Генетический дефект в одном из них может привести к дефициту, избытку или перераспределению железа в организме. Своевременное выявление и коррекция анемического синдрома могут улучшить качество жизни и выживаемость таких пациентов. Современные способы коррекции анемии хронических заболеваний, как правило, ограничиваются бесконтрольным применением препаратов железа. У больных с хронической почечной недостаточностью чаще всего используют рекомбинантный эритропоэтин, объясняя тактику лечения угнетением провоспалительными цитокинами синтеза эритропоэтина. В настоящее время разрабатывается ряд препаратов, непосредственно подавляющих синтез гепсидина или опосредованно регулирующих экспрессию стимуляторов и ингибиторов гепсидина. Некоторые лекарственные средства уже утверждены для клинического применения и могут успешно применяться для лечения железоперераспределительных анемий. Anemia of chronic disease is often associated with multiple chronic infectious diseases (infectious endocarditis, osteomyelitis, tuberculosis), cancer, rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, vasculitis), and chronic renal failure. The pathogenesis of this anemia is rather complex, diverse, and poorly understood. Hepcidin is an important peptide that regulates iron absorption in the intestine. Many upstream and downstream signaling pathways regulate expression of hepcidin. A genetic defect in one of them may lead to deficiency, excess or redistribution of iron in the body. Timely detection and correction of anemia can improve the quality of life and survival of patients. Modern methods for correction of anemia of chronic disease are usually limited to the uncontrolled use of iron supplements. The recombinant erythropoietin treatment is most commonly used in patients with chronic renal failure. These therapeutic tactics are usually explained by depression of erythropoietin synthesis by proinflammatory cytokines. Currently, a number of drugs is being developed, which inhibit hepcidin synthesis directly or indirectly by regulating expression of hepcidin inhibitors and stimulators. Some drugs have already been approved for clinical use and can be successfully used for treatment of anemia. In this review, we presented a new, pathogenetically well-grounded approach to the treatment of anemia of chronic disease.

The Nephroprotective Effects of the Herbal Medicine Preparation, WH30+, on the Chemical-Induced Acute and Chronic Renal Failure in Rats

2005 ◽  
Vol 33 (03) ◽  
pp. 491-500 ◽  
Author(s):  
Heidi H. Y. Ngai ◽  
Wai-Hung Sit ◽  
Jennifer M. F. Wan
Keyword(s):  
Renal Failure ◽  
Body Weight ◽  
Acute Renal Failure ◽  
Chronic Renal Failure ◽  
Serum Creatinine ◽  
Salvia Miltiorrhiza ◽  
Chinese Herb ◽  
The Body ◽  
Cordyceps Sinensis ◽  
Urea Nitrogen

In this study, we evaluated the renal protective effects of a Chinese herbal preparation WH30+in male Wistar rats with glycerol-induced acute renal failure and adenine-induced chronic renal failure. WH30+is a Chinese herb preparation composed of Rheum Palmatum, Salvia Miltiorrhiza, Cordyceps Sinensis, Leonurus Sibiricus, Epihedium Macranthum, Radix Astragali, and Radix Codonopsis Pilosulae, which has been used to treat kidney deficiency in human. An acute renal failure and chronic renal failure rat model were introduced by glycerol injection (i.m.) and fed with adenine-excessive diet, respectively. WH30+was administered to rats at the dose of 50 mg/kg/day from 10 days before the diseases were induced until the rats were sacrificed. A reduction in body weight ( p < 0.01) was observed in rats with chronic renal failure, but there was no difference between treatment groups. However, the body weight of rats with acute renal failure without treatment was significantly lower than those treated with WH30+( p < 0.05). Overall, serum creatinine and urea nitrogen were elevated significantly ( p < 0.01) in renal failure rats compared to control. Treatment with WH30+improved both serum creatinine and urea nitrogen slightly in both models. The WH30+-treated rats with acute renal failure had significantly ( p < 0.05) greater creatinine clearance than those without treatment. The results of the study show that WH30+is more effective in the prevention of acute renal failure than chronic renal failure.

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