Histopathological Spectrum of Premalignant and Malignant Lesions of Esophagus in the Population of Karachi

2020 ◽  
Author(s):  
Asma Shabbir
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Single Case ◽  
Malignant Neoplasms ◽  
Reference Laboratory ◽  
Histologic Pattern ◽  
Male Preponderance ◽  
Stratified Squamous Epithelium ◽  
Grade Ii ◽  
Diagnostic Research

Background: Squamous cell carcinoma (SCC) and adenocarcinoma are the most common esophageal cancers. Barrett’s esophagus is the change of esophageal stratified squamous epithelium to columnar cells which if remain undiagnosed follows the dysplasia – carcinoma sequence. The last two decades show a change in the histologic pattern of esophageal carcinoma. Adenocarcinoma is at majority rate than SCC in the West, however, in Asia, SCC is still the commonest cancer of esophagus. In this study, we aim to define a spectrum of premalignant and malignant neoplasms of esophagus in our region. Methods: This study was done at Dow Diagnostic Research and Reference Laboratory (DDRRL). All the cases of preneoplastic and neoplastic lesions of esophagus received during the period of 7 years (2009-2015) were reviewed. The data obtained were subjected to descriptive statistical analysis using SPSS version 21. Results: Out of 94 premalignant cases, 70 (74.5%) were diagnosed as Barrett’s esophagus, 23 (24.5%) as dysplasia and 1 (1.1%) as adenoma. From the total of 450 malignant cases, 395 (87.7%) were SCC, 54 (12%) were adenocarcinoma and a single case of leiomyoma was diagnosed. Grade II SCC was found to be most the common lesion. Conclusion: Barrett’s esophagus was more than dysplasia and showed male preponderance. SCC was the predominant esophageal cancer, which is similar to the other studies in our country. SCC was found more common in females than males and vice versa for adenocarcinoma. Majority of all the cases belonged to 41-60 years of age group.

scholarly journals Analysis of vibrodiagnostics methods in the technical state study of designed multimedia mobile scenes

2019 ◽  
Vol 302 ◽  
pp. 01011
Author(s):  
Marcin Łukasiewicz ◽  
Michał Liss ◽  
Natalia Dluhunovych
Keyword(s):  
Modal Analysis ◽  
Diagnostic Tests ◽  
Research Process ◽  
Technical Condition ◽  
Technical State ◽  
Normal Operation ◽  
Design Stage ◽  
Analysis Methods ◽  
State Study ◽  
Diagnostic Research

The paper presents the possibilities of using vibroacoustic methods in the study of the technical condition of designed multimedia mobile scenes. In particular, the possibility of implementing modal analysis methods in modelling and diagnostic research process has been presented. The use of virtual methods enables diagnostic tests both at the design stage and at the stage of normal operation, whereas modal methods help to explain the nature of the work of the element under investigation.

scholarly journals Problems in detecting misfit of latent class models in diagnostic research without a gold standard were shown

2016 ◽  
Vol 74 ◽  
pp. 158-166 ◽  
Author(s):  
Maarten van Smeden ◽  
Daniel L. Oberski ◽  
Johannes B. Reitsma ◽  
Jeroen K. Vermunt ◽  
Karel G.M. Moons ◽  
...  
Keyword(s):  
Gold Standard ◽  
Latent Class ◽  
Latent Class Models ◽  
Diagnostic Research ◽  
Class Models ◽  
Without A Gold Standard

scholarly journals Methodological and Methodical Principles of the Empirical Study of Spiritual Development of a Personality

2017 ◽  
Vol 4 (1) ◽  
pp. 42-47
Author(s):  
Olga Klymyshyn ◽  
Hanna Karpenko
Keyword(s):  
Spiritual Development ◽  
Personality Development ◽  
Human Person ◽  
Self Determination ◽  
General Index ◽  
Determination System ◽  
Age Patterns ◽  
Diagnostic Research ◽  
Methodological Principles ◽  
Spiritual Potential

The article reveals the essence of the methodological principles of the spiritual development of a personality. The results of the theoretical analysis of psychological content of spirituality from the positions of system and structural approach to studying of a personality, age patterns of the mental personality development, the sacramental nature of human person, mechanisms of human spiritual development are taken into consideration. The interpretation of spirituality and the spiritual development of a personality is given. Initial principles of the organization of the empirical research of the spiritual development of a personality (ontogenetic, sociocultural, self-determination, system) are presented. Such parameters of the estimation of a personality’s spiritual development as general index of the development of spiritual potential, indexes of the development of ethical, aesthetical, cognitive, existential components of spirituality, index of religiousness of a personality are described. Methodological support of psychological diagnostic research is defined

scholarly journals Badania diagnostyczne w glottodydaktyce – zalety i trudności

Neofilolog ◽  
1970 ◽  
pp. 183-194
Author(s):  
Krystyna Mihułka
Keyword(s):  
High School ◽  
Foreign Language ◽  
University Students ◽  
Intercultural Competence ◽  
Theoretical Framework ◽  
Language Teachers ◽  
Foreign Language Teachers ◽  
Diagnostic Studies ◽  
Diagnostic Research

The purpose of the following article is to discuss the theoretical framework of diagnostic research used in glottodidactics as well as to analyze some selected diagnostic studies conducted by Polish and German researchers in the last decade into the development of high school and university students’ and foreign language teachers’ intercultural competence. In the last part of this article attention is paid to the presentation and discussion of the most frequent problems which researchers encounter while planning and carrying out diagnostic studies.

scholarly journals Peranan Gejala Klinis dan Pemeriksaan Darah Tepi dalam Diagnosis Dini Influenza pada Pasien dengan Gejala Influenza Like Illness

2017 ◽  
Vol 1 (2) ◽  
pp. 96
Author(s):  
Adityo Susilo ◽  
Suhendro Suwarto ◽  
Iris Rengganis ◽  
Kuntjoro Harimurti
Keyword(s):  
Negative Predictive Value ◽  
Predictive Value ◽  
Influenza A ◽  
Prevalence Ratio ◽  
Influenza Like Illness ◽  
Diagnostic Research ◽  
Virus Influenza

Pendahuluan. Influenza merupakan penyakit infeksi yang disebabkan oleh virus influenza. Pada manusia, influenza sering menimbulkan penyakit pernapasan akut dengan manifestasi klinis berupa influenza like illness. Penegakkan diagnosis influenza seringkali sulit oleh karena manifestasi klinis yang tidak khas. Demam disebut sebagai gejala klinis terpenting dan limfopenia didapatkan sebagai suatu temuan laboratoris yang konsisten. Usaha untuk mengetahui proporsi dan mengelaborasi gejala klinis dan pemeriksaan darah tepi sederhana diperkirakan dapat meningkatkan probabilitas diagnosis influenza.Tujuan. Mengetahui proporsi influenza serta mengevaluasi peranan gejala klinis dan pemeriksaan laboratorium sederhana pada pasien penyakit pernapasan akut dengan influenza like illness sehingga dapat digunakan sebagai faktor prediktif terhadap diagnosis influenza.Metode. Studi potong lintang berbasis diagnostic research pada pasien penyakit pernapasan akut dewasa dengan gejala influenza like illness di Puskesmas Kecamatan Pulo Gadung dan Puskesmas Kelurahan Rawamangun antara Maret hingga Juni 2011. Spesimen analisis virus menggunakan bahan apus nasofaringeal, dengan teknik analisis PCR kualitatif dan imunokromatografi antigen.Hasil. Dari 90 orang subyek penelitian didapatkan 13 orang (14,4%) terbukti terinfeksi virus influenza A melalui teknik PCR. Variabel demam menunjukkan hasil uji kemaknaan yang signifikan terhadap influenza (p 0,003) dengan prevalence ratio 6,28 (95% CI 1,476-26,759). Sensitifitas demam, batuk dan pilek terhadap influenza masing-masing adalah 85% dan negative predictive value demam sebesar 98%. Variabel determinan lainnya tidak menunjukkan hasil yang bermakna terhadap influenza pada uji kemaknaan statistik.    Simpulan. Proporsi influenza pada pasien dengan gejala ILI diperoleh cukup tinggi dengan proporsi demam yang terbukti lebih tinggi pada pasien influenza. Sensitivitas demam, batuk dan pilek terhadap influenza tinggi dengan negative predictive value yang memuaskan untuk seluruh variabel determinan. 

scholarly journals Attitude and readiness of Dentistry students in Kerman University of Medical Sciences concerning Tele-dentistry in 2017

2017 ◽  
Vol 1 (4) ◽  
pp. 91-92
Author(s):  
Kambiz Bahaadinbeigi ◽  
Fatemeh Tabatabaei ◽  
Maryam Eslami Jahromi
Keyword(s):  
Dental Care ◽  
English Language ◽  
Public Awareness ◽  
Dental Students ◽  
Good Tool ◽  
Adequate Knowledge ◽  
Significant Difference ◽  
The Future ◽  
Knowledge And Attitude ◽  
Diagnostic Research

Introduction: Tele-dentistry is the use of information and telecommunications technology for dental care, counseling, education and public awareness in the same way as remote medical. Tele-dentistry is a relatively new field that can change the dental care system. However, many dentists are unaware of the goals, benefits, and how to participate. Therefore, this study was conducted to determine the knowledge and attitude of dental students regarding telemedicine. Methods:The present study is descriptive-analytic. The study population consisted of all dental students in Kerman in year 2017 and sample of 230 students selected by proportional sampling. For data collection, a complete English translation of an English-language article in the Journal of Clinical and Diagnostic Research, whose validity was confirmed by three of the leading medical informatics specialists in English, was then used to analyze the data using the software SPSS 19. Results: The findings of this study showed that there is no significant difference between the students' age, sex and term of education with their knowledge of tele-dentistry (P>0.05). Knowledge and attitude of 72% of students in tele-dentistry is very low. 40% of them said tele-dentistry would be very beneficial and more than half of them would be willing to do tele-dentistry in the future. 81% of them agreed that tele-dentistry could be a good tool for health education and oral health, and effective in educating the health of a large number of people. 75% of them felt that distance dental care saves time, and 81% of students believed that tele-dentistry was not financially feasible. Conclusion: The results of this study showed that many respondents lacked adequate knowledge and knowledge about tele-dentistry. Hence, there is a huge need for awareness among dentists to further the future of dentistry in the future. Therefore, it is suggested that the related institutions take more serious measures for awareness and education about tele-dentistry for students.

Sign in / Sign up

Export Citation Format

Share Document