Azadirachta Indica:Indian Neem,A Natural Killer of Microorganisms

Abstract-Medicinal Plants are always of immense vital component for pharmaceutical word. Azadirachta indica, commonly known as neem, has attracted worldwide prominence in recent years owing to its wide range of medicinal properties. Neem is a medicinal plant which is always at top from ancient world to modern world. The importance of the neem tree has been recognized by the US National Academy of Sciences, which published a report in 1992 entitled 'Neem- a tree for solving global problems'. Various parts of neem are sources for mankind to treat many severe diseases. More than 140 compounds have been isolated from different parts of neem. All parts of the neem tree- leaves, flowers, seeds, fruits, roots and bark have been used traditionally for the treatment of inflammation, infections, fever, skin diseases and dental disorders. Neem leafanditsconstituentshavebeendemonstrated to exhibit immunomodulatory, anti-inflammatory,antihyperglycaemic,antiulcer,antimalarial,antifungal,antibacterial,antiviral,antioxidant,antimutagenicandanticarcinogenicproperties. Keeping these points in view the present study is aimed to study antimicrobial activity of plant extracts prepared from leaves of neem plant against Klebsiella pneumoniae,Pseudomonasaeruginosa,Bacillus subtilis, Staphylococcus aureus and Escherichia coli. There is a significant antimicrobial activity observed by neem leave extract against these microbial strains.

2017 ◽  
Vol 3 (4) ◽  
pp. 383-391
Author(s):  
Mohd Asif Khan ◽  
Shashi Bhooshan Tiwari ◽  
Himanshu Gupta ◽  
Huma Noor

Since ancient time, herbal drugs were highly used in the prevention and cure of various human illnesses. In India, Azadirachta indica being commonly known as Neem or Margosa is one of the multi-functional trees; belonging to Meliaceae family. In 1992, the US National Academy of Sciences was published a report entitled ‘Neem- a tree for solving global problems’. It is still considered as ‘village dispensary’ throughout the India. There are two species of Azadirachta which have been investigated; Azadirachta indica that is found in the Indian subcontinent and Azadirachta excelsa Kack that is homegrown to Indonesia and Philippines. A large number of pharmacologically active substances have been identified and isolated from the different parts of neem including azadirachtin, meliacin, gedunin, salanin, nimbin, valassin and various other components which are derived from these main compounds. Many different studies have been evaluated and authenticated for its various traditional and pharmacological activities like itching, leprosy, wound healing, spermicidal, anti-inflammatory, insecticidal, antidiabetic and analgesic etc. In the beginning of 1979, patenting on neem was started by CSIR to separate the active compounds from neem oil. Its great implantation fights with soil erosion, global warming, deforestations and desertification world-wide. In 2002, World Neem Conference raised the neem tree as an industrial or commercial plant. This review is going to explore comprehensively; traditional, pharmacological potential along with patenting, environmental & industrial significant of various parts of neem tree with safety concerns.


2021 ◽  
Author(s):  
Christopher Keane ◽  
Susan Sullivan ◽  
Leila Gonzales

<p>The American Geosciences Institute in cooperation with its member societies has developed the Framework for Addressing Racial and Ethnic Equity in Geosciences Professional Societies.  The geoscience societies are a pivotal area to influence the culture of the geosciences, and in response to the events of June 2020, many societies determined they needed to directly act on the issue of equity in the geosciences. Being birthed from a federation of US-centric organizations, the Framework has clear US-aligned approaches and boundaries.  However, the baseline proposed actions are fundamentally universal and meet the goal of the authoring committee to provide a framework from which we hope geoscience organizations of all types would use it to craft their own specific action plan and policies.   A critical component of this framework for the committee was to ensure definable actions were included.   Some of these suggested actions and their intended extensions will be discussed.  Additionally, ongoing conversations among the societies, with the US National Academy of Sciences Board on Earth Science and Resources, and other science organizations have begun to examine what the path forward looks like.   One area that AGI particularly is concerned about is the process of measuring progress.   Understanding and recognizing the impacts of efforts like this is critical to ensure agile responses for success.   But with AGI's intimate knowledge of much of the U.S. federal data, some of the ambiguities and definitional challenges within the US system complicates the ability to directly measure progress and for which further discussion of what success looks like is critically needed.  </p>


Climate Law ◽  
2015 ◽  
Vol 5 (2-4) ◽  
pp. 252-294 ◽  
Author(s):  
William C. G. Burns ◽  
Jane A. Flegal

The feckless response of the world community to the mounting threat of climate change has led to a growing interest in climate geoengineering research. In early 2015, the us National Academy of Sciences released two major reports on the topic. While it is notable that both reports recommended some form of public participation to inform research, this article argues that the vagueness of these recommendations could mean that their implementation might not comport with optimal approaches for public deliberation. We outline some options for public deliberation on climate geoengineering and important design considerations.


The most important results of the scientific studies, carried out by the Institutes of the National Academy of sciences of Ukraine in the frames of the program for scientific research of the NAS of Ukraine "New Functional Substances and Materials for Chemical Engineering" in 2017-2021, are summarized. In the result of fulfillment of the projects of the Program a number of principally new organic, inorganic, polymeric substances and materials as well as composited based thereon of various functional destination were created, new energy-, resource-saving and ecologically-friendly ways for low-tonnage obtaining of substances and materials of chemical engineering were developed. Use of the obtained materials and methods of chemical substances obtaining in different fields of the national industry will improve the competitive capacity of the national products on the external and internal markets, will favor to significant reduction of the dependency of the country on import of deep technology chemical products, setting up of production of a wide range of chemical products, reagents and preparations in Ukraine.


2017 ◽  
Vol 1 ◽  
pp. 239784731769499 ◽  
Author(s):  
Edward J Calabrese

This commentary summarizes a spate of recent papers that provide historical evidence that the 1956 recommendation of the US National Academy of Sciences Biological Effects of Atomic Radiation I Genetics Panel to switch from a threshold to a linear dose–response model for risk assessment was an ideologically motivated decision based on deliberate falsification and fabrication of the research record. The recommendation by the Genetics Panel had far-reaching influence, affecting cancer risk assessment, risk communication strategies, community public health, and numerous medical practices in the United States and worldwide. This commentary argues that the toxicology, risk assessment, and regulatory communities examine this issue, addressing how these new historical evaluations affect the history and educational practices of these fields as well as carcinogen regulation.


2004 ◽  
Vol 34 (1) ◽  
pp. 21-38 ◽  
Author(s):  
KATHLEEN S. SHORT

Individuals and families may encounter difficulty making ends meet on many dimensions and there are a large number of measures designed to identify this group. In general, there is agreement that all of the approaches capture different pieces of the puzzle, while no single indicator can yield a complete picture. In an attempt to understand this multidimensional aspect of poverty, several measures are examined in this article: the official US poverty measure, a relative poverty measure, an experimental measure following recommendations of the US National Academy of Sciences, an index of material hardship, a measure of household debt, and responses to a question about inability to meet expenses. This study uses the 1996 panel of the Survey of Income and Program Participation (SIPP). The SIPP is a longitudinal survey that allows us to examine all of these various indicators for the same people over the period from 1996 to 1998. The study uses regression analysis to assess the relationship between and among the various indicators of economic hardship.


Author(s):  
Vladyslava Piskizhova ◽  

The purpose of the study is a historiographical analysis of the works of modern Ukrainian historians on the issues of ethnic history of the Greeks of Ukraine, who belong to its oldest and most stable ethnic communities. In this regard, several tasks are set, one of which is to define main thematic areas of these studies and the degree of their analysis. The methodology is based on the scientific principles of historicism and objectivity. Specific scientific methods of historiographic analysis, synthesis, ideographic and other methods were used. Scientific novelty is determined primarily by the fact that this topic within the outlined chronological boundaries has not become the subject of a separate scientific study so far. Conclusions: Development of issues of ethnic history of the Greeks of Ukraine, which was initiated in the studies of scholars from Western European countries and the Russian Empire at the end of the XVIII – XIX centuries and has evolved significantly thanks to the scientific achievements of Soviet historians, received a new impetus in the early 1990s in the works of Ukrainian historians. The emergence of another wave of scientific interest in this topic is associated with the reset of the national historical science after the proclamation of independence of Ukraine, the imperatives of state ethnopolitics, the demands of the Ukrainian public, etc. These developments are based on a wide range of newly discovered sources and are characterized by modern research approaches, rethinking key issues of the problem, developing new theories (primarily on the ethnogenesis of Urums and Roumeans), etc. It is determined that a significant contribution to the study of the issue was made by the staff of the Institute of History of Ukraine of the National Academy of Sciences of Ukraine, in particular the Cabinet of Ukrainian-Greek Relations (since 2007 – Research Center for Ukrainian-Greek Relations) headed by N.O. Terentyeva. Against the background of a wide variety of issues on the ethnic history of Ukrainian Greeks, which have a fairly high level of development today, primarily in the history of the Greeks of Nizhyn and North Azov region, their national and cultural life in independent Ukraine is the least represented


2021 ◽  
Vol 10 (2) ◽  
pp. 80-83
Author(s):  
Chris Margules

Conservation biology emerged as a scientific discipline in the mid-1980s with the explicit practical goal of conserving species and habitats. The term ‘biodiversity’ was coined soon after, apparently at some time during the organization of the September 1986 National Forum on Biodiversity held by the US National Academy of Sciences and the Smithsonian Institution. The science of conservation biology was quickly taken up. Journals proliferated and textbooks soon followed. Laboratories within university biology and ecology departments specialized in conservation biology. Along with a great many other young biologists and ecologists, I climbed the moral high ground and set about research to help change the future by discovering how to protect biodiversity.


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