scholarly journals Determining Role of TGF-β3 in Some Treatments of Albino Mouse, Mus musculus Linnaeus, 1758 Infected with Hydatid Cyst by Using an Immunohistoflourescent Staining Technique

2022 ◽  
Vol 6 (1) ◽  
pp. 58-67
Author(s):  
Afrah Sadek
Keyword(s):  
Body Weight ◽  
Hydatid Cyst ◽  
Hydatid Disease ◽  
Mus Musculus ◽  
Staining Technique ◽  
Hydatid Cysts ◽  
Treatment Efficiency

The present study was conducted as an attempt to treat secondary hydatid disease in white mice strain Balb/c by immunohistoflourescent (IHF) staining technique. For this purpose, the mice were infected with hydatid cysts and treatment was done by oxfendazole (OFZ) at a concentration of 30 mg/kg, praziquantel (PZQ) at a concentration of 40 mg/kg and albendazole (ABZ) at a concentration of 10 mg/kg of body weight. Each drug was given weekly for four months and the same concentrations as above. The results showed that the highest treatment efficiency was in case of OFZ + PZQ treated mice, while the groups treated with OFZ, OFZ + ABZ and ABZ + PZQ showed less treatment efficiency, respectively. The IHF staining technique was used to determine the cytokinesis of TGF-β3 in the spleen and liver of experimental mice. For this reason, OFZ is considered as one of the most promising chemotherapies used in the treatment of hydatid cysts.

scholarly journals Testes and body weight alteration related cardamom extract administration in mice

2019 ◽  
Vol 3 (1) ◽  
pp. 7
Author(s):  
Tyagita Hartady ◽  
Arvia Nisrina Praditha ◽  
Nabila Ayu Faza ◽  
Rini Widyastuti
Keyword(s):  
Body Weight ◽  
Mus Musculus ◽  
Point Of View ◽  
Average Weight

Cardamom is known as a plant with millions of benefits and it is known to contain aphrodisiac substances. The role of cardamom as an aphrodisiac need to be studied more deeply from the scientific point of view. The experimental object is a 3-month-old male white mice (<em>Mus musculus albinus</em>) with an average weight of about 30-35 grams. After being acclimatized for approximately 2 weeks, 35 mice were divided into 3 groups based on the dose of cardamom extract. At the end of the experiment, the mice will be sacrificed and then the testes were weighed and cauda epididymis were isolated to collect the sperm. Our findings suggested that the dose of administration has important role in affecting the weight of testes and bodies of mice. However, further studies on sperm profiles and optimal administration doses of cardamom extract are highly recommended.

scholarly journals Peritoneal hydatic cysts: a series of cases and the review of literature

2021 ◽  
Vol 17 (1) ◽  
pp. 20-36
Author(s):  
N. Vlad ◽  
C. Lupașcu ◽  
A. Vasilescu ◽  
Șt. Georgescu ◽  
C. Bradea ◽  
...  
Keyword(s):  
Hydatid Cyst ◽  
Hydatid Disease ◽  
Clinical Signs ◽  
Postoperative Mortality ◽  
Laparoscopic Approach ◽  
Signs And Symptoms ◽  
Surgical Excision ◽  
Hydatid Cysts ◽  
Cystic Tumors ◽  
Peritoneal Hydatidosis

Primary peritoneal hydatidosis is an extremely rare ( 2% of all intra-abdominal hydatid disease). Peritoneal hydatid disease is secondary to liver or splenic involvement following spontaneous rupture or accidental spillage during surgery. Methods: We made a retrospective study based on the analysis of the database of the I Surgery Clinic of the University Emergency Hospital „St. Spiridon ”from Iași, with peritoneal hydatid cyst, including all the data from the medical files. Between 1991 and 2021 a total of 18 patients were operated for primary (3) or secondary peritoneal cysts (15). During the same period, 1002 cases of hydatid cyst with various locations were treated in the Iasi Surgery Clinic: 805 abdominal (714 hepatic, 43 splenic, and 18 peritoneal) and 197 extra abdominal (thoracic, cervical, muscular, retroperitoneal, etc.). The incidence of hydatid diseases has decreased over time from 35 cases per year to 18 cases per year. In the year of the COVID pandemic (2020) the incidence decreased to 10 cases per year.Most of the patients with peritoneal hydatidosis were asymptomatic or had atypical symptoms. The diagnosis was based on the preoperative history, rupture of the cysts, serology, ultrasound and computer tomography. Open surgery was the procedure of choice (16 cases) with conservative (13 cysts) and radical (3 cysts) methods. The laparoscopic approach was performed in 2 cases of primary peritoneal hydatid cysts. Results: The outcome of surgery was good without postoperative mortality or severe morbidity and the recurrence rate was 22.2%. Conclusions: Peritoneal hydatidosis is a rare disease; it is important to prevent the disease. Clinical signs and symptoms are nonspecific for a long time.We suspect this diagnosis in the case of abdominal cystic tumors especially in endemic regions. The diagnosis is made based on the history of operated hydatid disease, clinical signs, imaging and immunological tests. Total surgical excision of hydatid cysts or partial perichystectomy after evacuation of the inactivated cyst is the chosen treatment. Proper perioperative medical treatment prevents recurrence. Long-term follow-up is necessary to detect and treat any recurrence.

scholarly journals Surgical Management of pleural Complications of Lung and Liver Hydatid Cysts in 34 Patients

2014 ◽  
Vol 8 (4) ◽  
pp. 15-19
Author(s):  
Manoucher Aghajanzadeh ◽  
Mohammad Reza Asgary ◽  
Ali Alavi Foumani ◽  
Syrus Emir Alavi ◽  
Siamak Rimaz ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Retrospective Study ◽  
Surgical Treatment ◽  
Hydatid Cyst ◽  
Surgical Management ◽  
Hydatid Disease ◽  
Endemic Area ◽  
Morbidity And Mortality ◽  
Hydatid Cysts ◽  
Common Procedure

The aim of this retrospective study was to review pleural complications and results of surgical management of patient with hydatid disease. Between 2000 and 2010, 34 patients among 260 patients with hydatid disease, were diagnosed with pleural complications. Findings are presented in relative frequencies tables. The most common pleural complication was empyema in 9 patients. The most common procedure was cystotomy, evacuation and decortication in 25 patients. In endemic area, pleural complications of hydatid cyst should be considered for differential diagnosis. And because of higher morbidity and mortality, surgical treatment should be carried out before complications.DOI: http://dx.doi.org/10.3126/ijls.v8i4.10893

scholarly journals Tailgut Cyst and Perineal Hydatid Cyst: A Case Report with Multimodality Imaging Findings

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Ibtisam Musallam Aljohani ◽  
Khalefa Ali Alghofaily ◽  
Sebastian R. McWilliams ◽  
Mnahi Bin Saeedan
Keyword(s):  
Case Report ◽  
Hydatid Cyst ◽  
Male Patient ◽  
Hydatid Disease ◽  
Multimodality Imaging ◽  
Presacral Space ◽  
Tailgut Cyst ◽  
Imaging Findings ◽  
Hydatid Cysts ◽  
Diagnostic Challenge

A tailgut cyst is a rare developmental lesion and usually is located in the retrorectal or presacral space. Extrahepatic hydatid disease has been reported in several locations including the pelvis and it often poses a diagnostic challenge. There are very few reported cases of primary perineal hydatid cysts. We present the multimodality imaging findings of a tailgut cyst and concurrent perineal hydatid disease in a 32-year-old male patient.

scholarly journals Comparative molecular study between some plant extract and tinidazole on hydatid cysts in Basra, southern Iraq

2019 ◽  
Vol 10 (3) ◽  
pp. 1675-1680
Author(s):  
Jalal Y. Mustafa ◽  
Ghazi Y. Azal ◽  
Suzan A. Al-Azizz ◽  
Fatin A. Muatafa ◽  
Arwa R. Lazim
Keyword(s):  
Public Health ◽  
Hydatid Cyst ◽  
Hydatid Disease ◽  
Plant Extract ◽  
Molecular Study ◽  
Health Problems ◽  
Hydatid Cysts ◽  
Capparis Spinosa ◽  
Southern Iraq

Hydatid disease or Echinoccosis is one of the serious public health problems. This study was designed as a comparative molecular study between some plant extract and tinidazole of sheep hydatid cysts in Basra province. In this study, 213 sheep were examined and the number of those infected with hydatid cysts was 75 (35.2 %). The results showed that hydatid cyst was detected successfully by performing PCR technique. In addition, Quercus aegilops has been shown the best plant extract for destroying all genes, the second plant extract which is Capparis spinosa showed destroying of two genes (G6-7, COI) and failed to destroy (sh4-1). Furthermore, Prosopis fracta has shown to destroy only (G6-7) and tinidazole failed to destroy any of these genes used in this study.

scholarly journals A Heavily Giant Calcified Hydatid Cyst of the Liver with Thoracic Involvement Presenting as an Abdominal Mass (A Very Rare Case Report): The Role of Imaging

2020 ◽  
Vol 2 (6) ◽  
Author(s):  
Mohammed Danfulani ◽  
Abubakar Musa ◽  
Ibrahim Haruna Gele
Keyword(s):  
Hydatid Cyst ◽  
Hydatid Disease ◽  
Rare Case ◽  
Abdominal Mass ◽  
The Body ◽  
Radiological Findings ◽  
Rare Case Report ◽  
Magnetic Resonance Imaging Mri ◽  
The Tropics

Hydatid disease is common in the tropics. It is caused by infection with the larval stage of Echinococcus tapeworm. Infestation of humans, who are accidentally the intermediate host, occurs from ingestion of water or food contaminated by fecal material of definitive host (dog, wolves, deer, sheeps). The most frequent organ of involvement is the liver in up to 70%, followed by the lung about 18% and with a lower reported incidence in other organs or tissues in the body. It primarily affects the liver and shows typical imaging findings. However clinical presentation varies widely and is non specific. Thus, imaging plays an important role in diagnosis of hydatid diseases. Ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) can depict hydatid disease. The imaging methods used depend on involved organ and the radiological findings which range from purely cystic lesions to completely solid appearance. We report a very rare case of a calcified huge hydatid cyst in a 42 year old patient to buttress the role of imaging in management of such cases.

scholarly journals Surgical excision of a cardiac hydatid cyst from the right ventricle in a child

2021 ◽  
Author(s):  
Alwaleed Al-Dairy ◽  
Rahim Abo Kasem
Keyword(s):  
Right Ventricle ◽  
Hydatid Cyst ◽  
Hydatid Disease ◽  
Rare Case ◽  
Surgical Excision ◽  
Hydatid Cysts ◽  
Life Threatening ◽  
The Right ◽  
Specific Symptoms

Cardiac Hydatid Cysts are uncommonly encountered entity of hydatid disease. Presentation may be with non-specific symptoms and sometimes with life threatening events. We present a rare case of a 9-year-old female who was diagnosed with a Cardiac Hydatid Cyst in the right ventricle, and underwent successful surgical excision

scholarly journals Giant intracranial hydatid cyst: A report of two cases and literature review

2012 ◽  
Vol 01 (01) ◽  
pp. 080-082 ◽  
Author(s):  
Anil Kumar ◽  
C.B. Sahay ◽  
T.J. Minj ◽  
Jeevesh Mallik
Keyword(s):  
Literature Review ◽  
Hydatid Cyst ◽  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Oral Route ◽  
Hydatid Cysts ◽  
Medical Sciences ◽  
Intracranial Hydatid Cyst

Abstract Hydatid disease is a zoonosis caused by Taenia echinococcus. The three main varieties Echinococcus granulosus, E. multilocularis and E. vogeli are primarily found in dogs and are transmitted to man by fecal–oral route. Commonly affected organs are liver, lungs and spleen. Brain is involved only in 2-5% cases. The authors herein present two cases of giant intracranial hydatid cysts managed at department of neurosurgery, Rajendra Institute of Medical Sciences, Ranchi, India.

scholarly journals Giant Isolated Hydatid Cyst of Spleen

2015 ◽  
Vol 1 (1) ◽  
pp. 7-11
Author(s):  
Mehdi Soufi ◽  
Ghizlane Kharrasse ◽  
Khanoussi wafae ◽  
Zahi Ismaili ◽  
Tijani El haroudi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Hydatid Cyst ◽  
Young Patient ◽  
Hydatid Disease ◽  
Gold Standard ◽  
Partial Cystectomy ◽  
Cystic Lesions ◽  
Imaging Findings ◽  
Hydatid Cysts ◽  
Spleen Preserving

Liver is most commonly involved organ in hydatid cyst. Primary splenic hydatid cysts are rare; we report a case of an isolated giant hydatid cyst of spleen in a 17-year-old man. The diagnosis was confirmed by imaging findings and serology. Partial cystectomy was performed with success. In cystic lesions of spleen, hydatid cyst should be kept in patrician’s mind in the differential diagnosis. Although splenectomy is the gold standard for treating hydatid disease of the spleen, in young patient spleen-preserving surgery seems give good results.

scholarly journals Uncommon Locations of Cystic Echinococcosis: A Report of 46 Cases from Southern Iran

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Reza Shahriarirad ◽  
Amirhossein Erfani ◽  
Mehrdad Eskandarisani ◽  
Mohammad Rastegarian ◽  
Bahador Sarkari
Keyword(s):  
Hydatid Cyst ◽  
Hydatid Disease ◽  
Cystic Echinococcosis ◽  
The Body ◽  
Pelvic Cavity ◽  
Fars Province ◽  
Hydatid Cysts ◽  
Unusual Location ◽  
Southern Iran ◽  
Demographical Data

Background. Most cases of hydatid cysts form in the liver and lung and other tissues are considered as unusual locations in hydatid cysts. The current study aimed to find out the rate and features of hydatid cysts in uncommon locations in Fars Province, Southern Iran, over a 15-year period. Methods. The hospital records of patients who underwent surgery for hydatid cysts in university-affiliated hospitals in Fars Province, Southern Iran, from 2004 to 2018, were retrospectively reviewed. For each patient, clinical and demographical data were recorded. Results. During a 15-year period, a total of 501 patients were surgically treated for hydatid cysts, and out of these, 46 (9.2%) were presented with the unusual locations of hydatid disease. Males constituted 28 (60.9%) of these patients while 18 (39.1%) of the patients were females. The patients’ age ranged from 5 to 80 years (mean = 40.49; SD = 20.37). The size of the cysts ranged from 2 to 20 cm (mean = 8.69, SD = 4.59). The most common unusual location for the hydatid cyst was the spleen with 30.4% of cases, followed by the pelvic cavity (15.2%). Out of 46 cases with unusual location of the hydatid cyst, 10 (21.7%) cases had lung, 22 (47.8%) cases had liver, and 5 (10.9%) cases had both liver and lung hydatid cysts, simultaneously with cysts in unusual locations. Conclusion. In cystic echinococcosis- (CE) endemic areas, hydatid disease can affect any organ, from head to toe, in humans. The disease should be considered in the differential diagnosis of any cystic entities anywhere in the body.

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