scholarly journals ALTERNATIVE OPTIONS FOR THE PLACEMENT OF ASSETS OF THE UNIFIED ACCUMULATIVE PENSION FUND

2021 ◽  
Vol 83 (4) ◽  
pp. 22-31
Author(s):  
A. A. Zhantaeva ◽  
Keyword(s):  
Pension Fund ◽  
Financial Instruments ◽  
Investment Portfolio ◽  
Short Period ◽  
Portfolio Managers ◽  
The Right ◽  
Structure Of Liquid ◽  
Level Of Risk

In this situation, the peculiarity of managing pension assets is that there are certain requirements for the structure of the investment portfolio, that is, the introduction of preliminary restrictions on the upper share of various categories of instruments in the investment portfolio. They are: by assets, by risk, by concentration of ownership, by issuer and by type of securities. Therefore, in the process of forming a portfolio of assets (shares), assets with the least volatility are selected, i.e. the initial goal is to preserve assets, then profitability. In this regard, investment portfolio managers need to create a structure of liquid financial instruments that can be converted into cash in a very short period of time and receive a stable income with a reasonable level of risk, and make the right decision, carefully comparing them with alternative financial instruments. ... The effectiveness of such strategies often depends on the ability to prioritize investment activities and combine objectives and core principles. The goal is to ensure the safety of investments.

Hypertriglyceridemia: An Infrequent, Difficult-to-predict, Severe Metabolic and Vascular Problem Associated with Estrogen Administration

2020 ◽  
Vol 18 (3) ◽  
pp. 254-261
Author(s):  
Thomas F. Whayne
Keyword(s):  
Acute Pancreatitis ◽  
Severe Side Effect ◽  
Recurrent Acute Pancreatitis ◽  
Postmenopausal Symptoms ◽  
Severe Hypertriglyceridemia ◽  
Short Period ◽  
Cv Disease ◽  
The Right ◽  
And Control ◽  
Transdermal Route

Supplementary estrogen plays important roles for female patients as convenient birth control, relief of postmenopausal symptoms, and in the management of other selected problems. However, as is the case for essentially all medications, there are side effects. Short of a major pulmonary embolus, the most severe side effect of estrogen would appear to be sporadic, rare, and severe hypertriglyceridemia associated with acute pancreatitis. The occurrence of this fortunately rare problem usually happens in the presence of some preexisting and usually mild increase in triglycerides (TG). A case of chronic and severe recurrent acute pancreatitis is described in the introduction and the management was complete estrogen avoidance. Started close to menopause and continued for a relatively short period, estrogens may have some cardiovascular (CV) benefit but the general recommendation is not to prescribe them for CV disease prevention. Estrogens may contribute to decreased diabetes mellitus (DM) risk and control. Administration of estrogens by the transdermal route may decrease some problems such as venous thromboembolism (VTE) and elevation of TG. Administration of estrogen in the right situation brings significant benefit to the female patient but skillful, careful, and knowledgeable use is essential.

HETEROTOPIC PREGNANCY WITH INEVITABLE ABORTION (RIGHT ADNEXAL LIVE ECTOPIC AND COEXISTING INTRAUTERINE TRIPLETS WITH ABSENT FETAL CARDIAC ACTIVITY)

2021 ◽  
pp. 58-59
Author(s):  
Jayanta Sarkar ◽  
Mini Sengupta
Keyword(s):  
Ectopic Pregnancy ◽  
Abdominal Cavity ◽  
Lower Abdominal Pain ◽  
Cardiac Activity ◽  
Exploratory Laparotomy ◽  
Sudden Onset ◽  
Heterotopic Pregnancy ◽  
Intrauterine Pregnancy ◽  
Short Period ◽  
The Right

Heterotopic pregnancy describes the occurrence of two or more pregnancies in different implantation sites simultaneously, intrauterine pregnancy coexists withectopic pregnancies (ampullary in 80%). A 27-year-old women (P ,L1) presented to the emergency department with a complaint of sudden onset of right-sided lower abdominal pain with 1+1 vaginal bleeding and had a short period of Amenorrhea. Ultrasonography demonstrated three intrauterine gestational sacwith foetal pole noted but Cardiac activity was absent . The right adnexa showed a heteroechoic area andmoderate amount of free uid was present in the lower abdominal cavity. Ectopic pregnancy was disturbed. An emergency exploratory laparotomy was performed under general anesthesia. Haemoperitoneum was found with a ruptured righttubal ectopic pregnancy as well. Both the ovaries appeared normaland a corpus luteal cyst was presentin right ovary. Right sided salpingectomy was performed with removal of the ectopic mass,heamostasis secured ,on table blood transfusion had been given.Suction evacuation had also been performed by manual vacuum aspirationon same sitting.Both the specimen send for histopathology. Histology conrmedGestational sac suggestive of an intra uterine pregnancy coexists with ectopic pregnancy. Left tube and both ovaries were found healthy. Episodes of PID also have a strong correlation with occurrence of ectopic gestation. Once diagnosis of heterotrophic pregnancy has been made the management is essentially surgical.

scholarly journals Riskmetrics™ Methodology in Assessment of Investment Risk on Capital Markets

2010 ◽  
Vol 9 (1) ◽  
pp. 34-51
Author(s):  
Grzegorz Mentel
Keyword(s):  
Capital Markets ◽  
Stock Exchange ◽  
Risk Measures ◽  
Market Risk ◽  
Investment Risk ◽  
Financial Instruments ◽  
Investment Portfolio ◽  
Warsaw Stock Exchange ◽  
Financial Portfolio

Riskmetrics™ Methodology in Assessment of Investment Risk on Capital Markets In the article the author has presented the methodology of assessment of market risk connected with investing in all sorts of financial instruments such as: shares, bonds and other derivatives, e.g. RiskGrade (RG). The measure has been introduced by RiskMetrics. The article presents the application of RiskGrades methodology while choosing the optimum investment portfolio for a Polish investor who invests in shares in the Warsaw Stock Exchange. Moreover, some other risk measures have been discussed which describe the efficiency of the optimum financial portfolio.

scholarly journals ELEMENTS OF CONTROL THEORY APPLIED TO AN INVESTMENT PORTFOLIO IN THE CAPITAL MARKET. THE OPTIMAL TIME HORIZON FOR SELLING A PORTFOLIO

2015 ◽  
Vol 1 (310) ◽  
Author(s):  
Jerzy Tymiński
Keyword(s):  
Capital Market ◽  
Stock Exchange ◽  
Optimal Time ◽  
Dynamic Programming Method ◽  
Financial Instruments ◽  
Investment Portfolio ◽  
Warsaw Stock Exchange ◽  
Investment Portfolios ◽  
Rational Investment ◽  
The Capital Market

The article presents a concept of capital management for assembling investment portfolios. Two optimization variants of a portfolio to be purchased are discussed. Portfolio I is structural, using the „traditional model”. To assemble Portfolio II, elements of reliability theory and the dynamic programming method were used. The article also analyses the sale of a portfolio with respect to the demand for financial instruments in the capital market. The presented concept dealing with rational investment decisions during transactions at the Warsaw Stock Exchange can also be used by managers to create an effective portfolio of financial instruments.

Short-Latency Crossed Inhibitory Responses in Extensor Muscles During Locomotion in the Cat

2008 ◽  
Vol 99 (2) ◽  
pp. 989-998 ◽  
Author(s):  
Alain Frigon ◽  
Serge Rossignol
Keyword(s):  
Gluteus Medius ◽  
Short Latency ◽  
Triceps Surae ◽  
Step Cycle ◽  
Bipolar Electrodes ◽  
Cutaneous Reflex ◽  
Cuff Electrode ◽  
Short Period ◽  
Excitatory Responses ◽  
The Right

During locomotion, contacting an obstacle generates a coordinated response involving flexion of the stimulated leg and activation of extensors contralaterally to ensure adequate support and forward progression. Activation of motoneurons innervating contralateral muscles (i.e., crossed extensor reflex) has always been described as an excitation, but the present paper shows that excitatory responses during locomotion are almost always preceded by a short period of inhibition. Data from seven cats chronically implanted with bipolar electrodes to record electromyography (EMG) of several hindlimb muscles bilaterally were used. A stimulating cuff electrode placed around the left tibial and left superficial peroneal nerves at the level of the ankle in five and two cats, respectively, evoked cutaneous reflexes during locomotion. During locomotion, short-latency (∼13 ms) inhibitory responses were frequently observed in extensors of the right leg (i.e., contralateral to the stimulation), such as gluteus medius and triceps surae muscles, which were followed by excitatory responses (∼25 ms). Burst durations of the left sartorius (Srt), a hip flexor, and ankle extensors of the right leg increased concomitantly in the mid- to late-flexion phases of locomotion with nerve stimulation. Moreover, the onset and offset of Srt and ankle extensor bursts bilaterally were altered in specific phases of the step cycle. Short-latency crossed inhibition in ankle extensors appears to be an integral component of cutaneous reflex pathways in intact cats during locomotion, which could be important in synchronizing EMG bursts in muscles of both legs.

scholarly journals Solar keratoma: An atypical case

2015 ◽  
Vol 86 (1) ◽  
Author(s):  
Sean M. Miller ◽  
Ralph H. Katzwinkel
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Atypical Case ◽  
Short Period ◽  
The Right

This case report shows that keratomas can occur in both hind feet of equine patients and should be considered as a diagnosis for long-standing, intermittent lameness localised to the hooves. A Thoroughbred racehorse presented with long-standing abscessation of the right hind hoof. Owing to the long-standing nature, the abscess draining tract was surgically explored. A focal mass was found within the solar horn. Histopathology revealed the mass to be a keratoma. A similar mass was removed from the left hind hoof a few months later after similar presenting signs. This case shows that keratomas can occur in more than one hoof within a short period and should be considered a differential diagnosis for long-standing lameness localised to the hoof.

Indexing long-term financial contracts

1981 ◽  
Vol 108 (3) ◽  
pp. 299-360 ◽  
Author(s):  
A. D. Wilkie
Keyword(s):  
Beneficial Effect ◽  
Price Index ◽  
Pension Fund ◽  
Financial Instruments ◽  
Financial Contracts ◽  
Life Assurance ◽  
The United Kingdom ◽  
Insight Into ◽  
Assurance Contracts

This paper has two functions: first, in part 1, to present briefly the results of some recent investigations into the behaviour of a price index (in the United Kingdom) in order to gain some insight into the possible future progress of inflation; secondly, in parts 2–4, to present the arguments in favour of the linking to a price index of financial instruments, in particular government stocks, life assurance contracts and pension fund benefits. Part 1 is heavily statistical, and those who prefer the controversial material can go straight to part 2, noting only the conclusion to part 1, viz.: that it is not easy to forecast inflation over any lengthy period. Parts 2–4 are controversial, and I expect will still be topical when the paper is presented. I make no pretence to be impartial; I am convinced that widespread index-linking of long-term contracts would have a beneficial effect on the conduct of our financial affairs. It is up to those who disagree with me to put their case in the discussion; but I hope my supporters will express their views too.

rTMS age-dependent response in treatment-resistant depressed subjects: a mini-review

CNS Spectrums ◽  
2012 ◽  
Vol 17 (1) ◽  
pp. 24-30 ◽  
Author(s):  
Stefano Pallanti ◽  
Andrea Cantisani ◽  
Giacomo Grassi ◽  
Sarah Antonini ◽  
Chiara Cecchelli ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Rating Scale ◽  
Low Frequency ◽  
Treatment Resistant ◽  
The Third ◽  
Depressed Patients ◽  
Medical Disorders ◽  
Short Period ◽  
The Right ◽  
Low Frequency Rtms

BackgroundIn old age, depressive syndromes often affect people with chronic medical illnesses, cognitive impairment, and disability, which can worsen the outcomes of other medical disorders and promote disability. Repetitive magnetic transcranial stimulation (rTMS) is a simple and effective treatment in patients with treatment-resistant depression. Therefore the use of rTMS could be of particular potential benefit in treatment-resistant elderly patients, who often cannot tolerate the higher doses of drugs needed or show phenomena of intolerance and interaction. However, several studies assessing the efficacy of rTMS found smaller response rates in elderly patients when compared to younger samples. Nevertheless, the correlation between age and response is still a controversial issue, and there is no strong evidence to date. The aim of our study was to retest the effectiveness and safety of low-frequency rTMS in a 3 weeks active treatment in a group of resistant-depressed patients, and to investigate the role of age in the response to stimulation treatment.MethodsEnrolled in this study were 102 treatment-resistant depressed patients. The patients were treated with low-frequency rTMS over the right dorso-lateral prefrontal cortex (DLPFC) for 3 weeks with a simple protocol (420 pulses per session for 15 sessions). At baseline, at the end of the second week, and at the end of the third week of treatment, the Hamilton Depression Rating Scale (HAM-D) and the Hamilton Anxiety Rating Scale (HAM-A) were administered.ResultsLow-frequency rTMS on the prefrontal dorsolateral right area resulted in a statistically significant reduction of mean HAM-D scores in the entire group of patients at the end of treatment. The responder's rate in the whole group at the end of the third week was 56.86%. A significant inverse relationship between HAM-D reduction and age was found in the “older” (>60 years old) group, not in the “younger” (<60 years old) group.ConclusionResults from this study show that low-frequency rTMS over the right DLPFC, with a relatively low number of pulses (420 pulses per session) and a relatively short period of treatment, is effective in the treatment of resistant patients (in a sample also including elderly patients) in a 3-weeks treatment protocol with a low reduction with the progress of age. Furthermore, we found a greater response in younger patients and an inverse correlation between age and treatment response. Adaptations of the protocol according to age are reviewed.

scholarly journals Patency of Cerebral Microvessels after Focal Embolic Stroke in the Rat

2001 ◽  
Vol 21 (4) ◽  
pp. 413-421 ◽  
Author(s):  
Chen Xu Wang ◽  
Kathryn G. Todd ◽  
Yi Yang ◽  
Tessa Gordon ◽  
Ashfaq Shuaib
Keyword(s):  
Evans Blue ◽  
Internal Carotid ◽  
Focal Cerebral Ischemia ◽  
Time Intervals ◽  
Cerebral Microvessels ◽  
Lower Blood ◽  
Short Period ◽  
Neuroprotective Strategies ◽  
The Right ◽  
Downstream Movement

In patients with thrombotic stroke, the occluded artery often reopens over time. This results through a natural dissolution of the occluding material, and fragments of the material may move downstream to obstruct distal arteries. The current study was undertaken to investigate the patency of brain microvessels at varying time intervals after injection of a preformed clot into the right internal carotid artery of rats. Cerebral microvessels in brain sections were visualized using immunohistochemistry for fibronectin (detecting existing microvessels) and Evans blue (visualizing perfused microvessels). The percentage of patent microvessels was calculated as the number of Evans blue-positive microvessels divided by the number of fibronectin-positive microvessels. In normal control animals, results showed that 98% ± 3% (mean ± SD) of microvessels in the cortex and 94% ± 14% in the striatum were patent. In the ischemic animals, immediately after clot injection, microvessels in the cortex and striatum were occluded, mainly in the territory irrigated by the middle cerebral artery. One hour after clot injection, microvessels had reopened in most of the cortex but remained occluded in some portions of the striatum, possibly as a result of downstream movement of fragments formed from the original clot. By 3 hours after clot injection, microvessels in the cortex were patent in all animals, whereas in the striatum microvessels were patent in 50% of the animals. In the other 50%, small striatal perfusion deficits persisted. At 24 hours after clot injection, microvessels were patent in both the cortex and striatum of all animals except one. These findings suggest that intracerebral clots dissolve spontaneously in a relatively short period of time, but that fragments formed from the clot may obstruct more distal blood vessels. It is likely that clot fragments lodge in arteries with lower blood flow and poor collateral perfusion, where they continue to cause ischemia for a longer duration. These results may in part explain the resistance of the striatum to neuroprotective strategies used for the treatment of focal cerebral ischemia.

scholarly journals Maternity (Family) Capital as a Support Program for Families with Children: Implementation Results and Development Prospects (Part Two)

2020 ◽  
Vol 16 (4) ◽  
pp. 21-35
Author(s):  
Valeriy Elizarov ◽  
Natal’ya Dzhanayeva
Keyword(s):  
Pension Fund ◽  
Social Protection ◽  
State Budget ◽  
Family Capital ◽  
New Directions ◽  
The Russian Federation ◽  
C Program ◽  
The Right ◽  
Families With Children ◽  
Development Prospects

Maternity (family) capital (hereinafter referred to as M(F)C) is a certain amount of funds allocated to families with children from the state budget with the goal of creating conditions providing families with children with The article analyzes the theoretical and practical issues of the development of the M(F)C program, the statistics of Rosstat, the Ministry of Labour and Social Protection and the Pension Fund of the Russian Federation, characterizing M(F)C. The article is divided into two parts due to its large volume. The first part of the article explores the conceptual and applied aspects of the origin and development of the M(F)C program. The genesis of the idea of maternal capital and the path from idea to bill is considered. The baseline parameters, such as the size of the capital, the period of action, the directions of use and the conditions governing access to funds M(F)C are analyzed. The second part shows how the initial parameters were adjusted: the extension of the period of action, the reduction of the period preceding the possibility of use, the clarification of the rules of documentation of the right to M(F)C, the removal of unnecessary administrative barriers for filing and consideration of applications, improving the conditions of use by adding new directions. The statistics of M(F)C, changes in the direction of its use and expenditures on these areas are analyzed. Proposals are presented to develop the M(F)C program, to expand its use to better support families with children

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