Medicinal Plants and Natural Dietary Supplements with Anti-Obesity Therapeutic Effects for Treatment of Different Kinds of Hepatitis

2022 ◽  
Author(s):  
Mohamad Hesam Shahrajabian ◽  
Wenli Sun
Author(s):  
Ramin Ansari ◽  
Amirhossein Dadbakhsh ◽  
Fatemeh Hasani ◽  
Fatemeh Hosseinzadeh ◽  
Zohreh Abolhassanzadeh ◽  
...  

: Sciatica is a common back pain caused by irritation of the sciatic nerve. Current pharmacologic therapies have proven inadequate for many patients with sciatic pain. On the other hand, there is a global increasing demand toward the use and administration of natural medicaments for this disorder. Traditional Persian Medicine (TPM) is a school of medicine and a medicinal plant based resource for clinical studies put forward by Persian scholars. The aim of the present study is to gather and study the effectiveness of all medicinal plants from five main Persian pharmacopeias. Furthermore, different data bases such as PubMed and Scopus have been checked to derive relevant activities for these plants. In all, 99 medicinal plants related to 42 families have been authenticated. Asteraceae and Apiaceae were the most frequent families and Roots and Seeds were the most reported botanical parts. The employed routs of administration were oral (54%), topical (33%) and rectal (13%). Anti-inflammatory, analgesic activity and anti-nociceptive properties of medicines are known as some main mechanisms to manage sciatic pain. These functions are possessed by 30%, 15%, and 15% of the studied plants, respectively. Medicaments that can be introduced as lead agents for further investigation are Zingiber officinale Roscoe, Olea europaea L., Strychnos nux-vomica L and Artemisia vulgaris L which showed all of these properties in previous studies. Hence, conducting adducible clinical trials using these lead agents may lead to novel drugs with lesser undesirable and much more therapeutic effects on controlling sciatic pain.


2021 ◽  
Vol 134 ◽  
pp. 111101
Author(s):  
Faeze Keihanian ◽  
Mohsen Moohebati ◽  
Amin Saeidinia ◽  
Seyed Ahmad Mohajeri ◽  
Saeid Madaeni

2012 ◽  
Vol 40 (02) ◽  
pp. 321-334 ◽  
Author(s):  
Jeong-Won Lee ◽  
Sok Cheon Pak ◽  
Songhee Jeon ◽  
Dong-Il Kim

Yukmijihwangtang (YM), a boiled extract of medicinal plants, has been prescribed for patients with kidney dysfunction in Korea; however, the mechanism underlying its therapeutic effects has not been fully elucidated. This study was conducted to evaluate the beneficial effects on bladder function by using modified YM (M-YM), which included Ulmi radicis cortex in addition to the six traditional medicinal plants in YM. Bladder irritation of the rats was caused by intravesical instillation of HCl . The animals were divided into six groups: sham group, cystitis-injury group with no treatment, cystitis-injury group with prednisolone treatment (5 mg/kg), and cystitis-injury with M-YM treatment (100, 200 or 500 mg/kg groups). Whole bladders were collected at day eight after injury. Samples were analyzed by histological and immunological examinations. An in vitro study was performed to determine whether M-YM extracts inhibit lipopolysaccharide (LPS)-induced nitric oxide (NO) production and I κ B phosphorylation in a human uroepithelial cell line of T24 cells. Administration of M-YM notably improved bladder histological changes, and suppressed IL-6/TNF α production and I κ B phosphorylation in a rat model of chronic cystitis. M-YM also inhibited LPS-induced NO production and I κ B phosphorylation in T24 cells. This study suggests that administration of M-YM might be an applicable therapeutic traditional medicine for the treatment of interstitial cystitis.


2020 ◽  
pp. 270-288
Author(s):  
Vítězslav Vilímek

This study focuses on the names of medicinal plants which are used in the linguistic area of Těšín Silesia and which have been derived from their eff ects known in folk human and veterinary medicine. The etymol-ogy of the names of these plants was transparent to the average speaker of the language and acted as a clear guide on how to use them. It is therefore a suitable source of ethnolinguistic knowledge. We identify four typical types of motivation: the organ or part of body for which the plant is used; the disease against which the plant is used; the eff ect; the person or animal for whose treatment the plant is used. Each type is documented using specifi c examples and aided by analyses of the origin of the name of the plant and its therapeutic use as it is known in Těšín Silesia. In interesting cases, comparison with contemporary Czech and other Slavic languages is also carried out.


2020 ◽  
Vol 9 (1) ◽  
pp. 112
Author(s):  
Adriane Cordeiro Trevisani ◽  
João Pedro Cordeiro Trevisani ◽  
Moacir Haverroth ◽  
Ailton Da Cruz Melo ◽  
Isabela Carvalho dos Santos ◽  
...  

Ayahuasca is a drink of indigenous origin made as a decoction obtained from medicinal plants found mainly in Acre, state of Brazil, which are the leaves of Psychtoria viridis, popularly known as “chacrona” in Brazil, and the stem of Banisteriopsis caapi, commonly known as mariri or jagube. The decoction is used in religious practices for the therapy of diseases that affect the human being, such as psychological disorders, neurological, parasitic and bacterial infections. Considering the existing bioactive compounds and the therapeutic potential of ayahuasca, this study aims to carry out a literature review of scientific articles (PubMed, Scielo and LILACS) in order to gather knowledge within 30 years of study about the therapeutic potentials of ayahuasca. In the current literature, the studies focus on the area of neuropsychology, dealing with ayahuasca as a form of therapy for neurological and neuromotor disorders. In addition, antimicrobial, antiparasitic, immunomodulatory, and antioxidant actions have already been reported. However, new studies are still needed in these areas in order to evaluate the efficacy and safety of ayahuasca and its component plant species, in order to use it as an alternative therapy, especially in the population from which the traditional knowledge about this beverage came from.


2021 ◽  
Vol 7 (3) ◽  
pp. 038-044
Author(s):  
Pradeep Kumar

The traditional medicinal plants are believed to be an impotent source of phytochemicals with potential therapeutic effects, and caring for different diseases. The plant Solanum surattense has active phytochemicals like saponins, alkaloid, phenols, solamargine, solasurine, solasonine, gum, ascorbic acid, sterols, torvoside K, torvoside L, khasianine, glycosides, flavonoids, aculeatiside A, solamargine, glycoalkaloid, steroidal compound, steroidal alkaloids, polyphenol (caffeic acid), coumarins (esculentin and aesculin), steroids (carpesterol, campesterol, daucosterol, stigmasterol, cycloortanol, and cholesterol), triterpinins, and sapogenin. This medicinal plant is widespread in pharmaceutics and still presents a large source of active phytochemicals with different activity such as antimicrobial, anti-larvicidal, anthelmintic, antimalarial, antioxidant, antidiabetic, anti-asthmatic, and anti-cancerous. This review of the literature revealed new researches on the phytochemicals of S. surattense that how the active phytochemicals are performed different activities on the molecular level in vital aspects.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sha Li ◽  
Chien-Shan Cheng ◽  
Cheng Zhang ◽  
Guo-Yi Tang ◽  
Hor-Yue Tan ◽  
...  

Background: The outbreak of the pandemic coronavirus disease 2019 (COVID-19) has now become a global pandemic spreading throughout the world. Unfortunately, due to the high infectiousness of the novel β-coronavirus, it is very likely to become an ordinary epidemic. The development of dietary supplements and functional foods might provide a strategy for the prevention and management of COVID-19.Scope and Approach: A great diversity of potential edible and medicinal plants and/or natural compounds showed potential benefits in managing SARS, which may also combat COVID-19. Moreover, many plants and compounds have currently been proposed to be protective against COVID-19. This information is based on data-driven approaches and computational chemical biology techniques. In this study, we review promising candidates of edible and medicinal plants for the prevention and management of COVID-19. We primarily focus on analyzing their underlying mechanisms. We aim to identify dietary supplements and functional foods that assist in managing this epidemic.Key findings and Conclusion: We infer that acetoside, glyasperin, isorhamnetin, and several flavonoid compounds may prevent and/or be effective in managing COVID-19 by targeting the viral infection, reducing the host cytokine storm, regulating the immune response, and providing organ protection. These bioactive dietary components (used either alone or in combination) might assist in the development of dietary supplements or functional foods for managing COVID-19.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Fifonsi A. Gbeasor-Komlanvi ◽  
Wendpouiré I. C. Zida-Compaore ◽  
Ikpindi H. Dare ◽  
Aboudoulatif Diallo ◽  
Tchin P. Darre ◽  
...  

Background. In the sub-Saharan African, region of the world with a fast growing aging population and where the use of herbal products is very common, there is a paucity of data on medication consumption patterns among elderly people. The objective of this study was to assess the prevalence of polypharmacy and its associated factors among community-dwelling elderly in Lomé, Togo, in 2017. Methods. A cross-sectional study was conducted from March to June 2017 in Lomé, Togo among people aged 60 years and older. The Respondent Driven Sampling method was used to recruit participants. Data on socio-demographic characteristics and medication consumption patterns, including the use of medicinal plants and dietary supplements, were collected using a standardized questionnaire during a face-to-face interview at participants’ home. Descriptive and binary logistic regression analyses were performed. Results. A total of 370 participants with median age 65 years, (IQR: 62–71) were enrolled in the study. Almost three elderly in five (57.6%) were multimorbid (had two or more chronic diseases). Conventional drugs (78.4%), medicinal plants (14.3%) and other dietary supplements (9.5%) were used by participants. The prevalence of polypharmacy was 22.7% (95% CI: 18.5–27.3%). Concurrent use of conventional drugs and medicinal plants or other dietary supplements was observed among 17.0% of participants and 67.3% reported self-medication. Multimorbidity (aOR = 4.55; 95% CI: [2.42–8.54]) and female sex (aOR = 1.86; 95% CI: [1.00–3.47]) were associated with polypharmacy. Conclusion. One elderly in five uses five or more medications in Togo. Further studies are needed to assess drug-drug interactions and herb-drug interactions among this population.


2020 ◽  
Vol 6 (4) ◽  
pp. 278-299 ◽  
Author(s):  
Anjoo Kamboj ◽  
Ishtdeep Kaur ◽  
Narinder Kaur

Background: Herbal drugs play a significant role to maintain the human healthiness and to treat the ailments since the dawn of civilization. Moreover, these plants have provided many lead compounds that culminated in modern medicine. A single herb is regarded as mini-combinatorial library of phytoconstituents hence the quality control of herbal drugs in an herbal formulation is not an easy task because a number of factors impact their pharmacological efficiency and consistent therapeutic effects. Hence, to provide consistent beneficial therapeutic effects, standardized herbal products of consistent quality and purity are required. Methods: This review is based on publications obtained by a selective search in PubMed using the keywords “Standardized herbal products”, “fingerprinting”, “authentication”, “chemometric, hyphenated techniques”, “quality control of herbal drugs”, “identification”. Results: In the era of modernization, chromatographic techniques coupled with sophisticated spectroscopic analytical methods are used in estimating the authenticity, identity and characteristic of herbal products. Further, with the advancement of computer technology, chemometrics methods have become a leading tool with an unsupervised pattern recognition technique for handling multivariate data without prior knowledge about the studied samples and mines more beneficial and valuable information about the chemical entities from the raw data. Conclusion: Standardization of HDs chromatographic fingerprint is not always a perfect way to present all compounds. To assess the quality of medicinal plants, new ways are regularly being explored such as combination chemical fingerprint with biological methods, biofingerprint and metabolic fingerprint quality metrology, pharmacodynamics and export system of medicinal plants have been researched in some groups but still a significant amount of work is required to achieve a perfect system for quality evaluation of herbal drugs. Further, novel chemometric techniques have been unfolded that mines more beneficial and valuable information about the chemical entities from the raw data. So this review emphasis mainly on hyphenated techniques associated with chemometric method used in herbal drugs for identifying more valuable information and various methods for providing data, among which most commonly used techniques are chemometric resolution method and Principal Component Analysis (PCA) method.


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