scholarly journals A Systematic Literature Review of the Potential Therapeutic Effects of Ayahuasca Tea Prepared From the Use of Banisteriopsis Caapi and Psychotria Viridis

2020 ◽  
Vol 9 (1) ◽  
pp. 112
Author(s):  
Adriane Cordeiro Trevisani ◽  
João Pedro Cordeiro Trevisani ◽  
Moacir Haverroth ◽  
Ailton Da Cruz Melo ◽  
Isabela Carvalho dos Santos ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Literature Review ◽  
Traditional Knowledge ◽  
Plant Species ◽  
Bioactive Compounds ◽  
Bacterial Infections ◽  
Therapeutic Potential ◽  
Alternative Therapy ◽  
Therapeutic Effects ◽  
Efficacy And Safety

Ayahuasca is a drink of indigenous origin made as a decoction obtained from medicinal plants found mainly in Acre, state of Brazil, which are the leaves of Psychtoria viridis, popularly known as “chacrona” in Brazil, and the stem of Banisteriopsis caapi, commonly known as mariri or jagube. The decoction is used in religious practices for the therapy of diseases that affect the human being, such as psychological disorders, neurological, parasitic and bacterial infections. Considering the existing bioactive compounds and the therapeutic potential of ayahuasca, this study aims to carry out a literature review of scientific articles (PubMed, Scielo and LILACS) in order to gather knowledge within 30 years of study about the therapeutic potentials of ayahuasca. In the current literature, the studies focus on the area of neuropsychology, dealing with ayahuasca as a form of therapy for neurological and neuromotor disorders. In addition, antimicrobial, antiparasitic, immunomodulatory, and antioxidant actions have already been reported. However, new studies are still needed in these areas in order to evaluate the efficacy and safety of ayahuasca and its component plant species, in order to use it as an alternative therapy, especially in the population from which the traditional knowledge about this beverage came from.

scholarly journals Therapeutic Effects of Medicinal Plants on Cutaneous Wound Healing in Humans: A Systematic Review

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Tarcisio Vitor Augusto Lordani ◽  
Celia Eliane de Lara ◽  
Fabiana Borges Padilha Ferreira ◽  
Mariana de Souza Terron Monich ◽  
Claudinei Mesquita da Silva ◽  
...  
Keyword(s):  
Systematic Review ◽  
Medicinal Plants ◽  
Human Skin ◽  
Plant Species ◽  
Therapeutic Potential ◽  
Healing Process ◽  
Skin Lesions ◽  
Therapeutic Effects ◽  
Cutaneous Lesions ◽  
Cutaneous Wounds

The pharmaceutical industry has made great strides in providing drugs that are able to stimulate the healing process, but only 1–3% of all drugs that are listed in Western pharmacopoeias are intended for use on the skin or cutaneous wounds. Of these, at least one-third are obtained from plants. We sought to review the therapeutic effects of medicinal plants on human skin lesions. For this systematic review, we searched the PubMed, Scopus, and Web of Science databases to identify clinical trials that were published from 1997 to 2017. We reviewed studies that described the use of medicinal plants for the treatment of skin lesions in humans. Ten studies were selected, eight of which were published from 2007 to 2016, with a total of 503 patients. Among the plant species that were used for the treatment of human skin lesions, 12 belonged to 11 families and were included in the analysis. All of the plant species that were studied presented high therapeutic potential for the treatment of cutaneous lesions.

Medicinal Plants and Bioactive Compounds for Diabetes Management: Important Advances for Drug Discovery

2020 ◽  
Vol 26 ◽  
Author(s):  
Kondeti Ramudu Shanmugam ◽  
Bhasha Shanmugam ◽  
Gangigunta Venkatasubbaiah ◽  
Sahukari Ravi ◽  
Kesireddy Sathyavelu Reddy
Keyword(s):  
Herbal Medicine ◽  
Medicinal Plants ◽  
Bioactive Compounds ◽  
Diabetes Management ◽  
Therapeutic Potential ◽  
Public Health Problem ◽  
In Vivo Studies ◽  
Major Public Health Problem

Background : Diabetes is a major public health problem in the world. It affects each and every part of the human body and also leads to organ failure. Hence, great progress made in the field of herbal medicine and diabetic research. Objectives: Our review will focus on the effect of bioactive compounds of medicinal plants which are used to treat diabetes in India and other countries. Methods: Information regarding diabetes, oxidative stress, medicinal plants and bioactive compounds were collected from different search engines like Science direct, Springer, Wiley online library, Taylor and francis, Bentham Science, Pubmed and Google scholar. Data was analyzed and summarized in the review. Results and Conclusion: Anti-diabetic drugs that are in use have many side effects on vital organs like heart, liver, kidney and brain. There is an urgent need for alternative medicine to treat diabetes and their disorders. In India and other countries herbal medicine was used to treat diabetes. Many herbal plants have antidiabetic effects. The plants like ginger, phyllanthus, curcumin, aswagandha, aloe, hibiscus and curcuma showed significant anti-hyperglycemic activities in experimental models and humans. The bioactive compounds like Allicin, azadirachtin, cajanin, curcumin, querceitin, gingerol possesses anti-diabetic, antioxidant and other pharmacological properties. This review focuses on the role of bioactive compounds of medicinal plants in prevention and management of diabetes. Conclusion: Moreover, our review suggests that bioactive compounds have the potential therapeutic potential against diabetes. However, further in vitro and in vivo studies are needed to validate these findings.

A review on phytochemical and therapeutic potential of Iris germanica

2021 ◽  
Author(s):  
Bahareh Sadat Yousefsani ◽  
Motahareh Boozari ◽  
Kobra Shirani ◽  
Amirhossein Jamshidi ◽  
Majid Dadmehr
Keyword(s):  
Bioactive Compounds ◽  
Therapeutic Potential ◽  
Experimental Studies ◽  
Therapeutic Effects ◽  
Pharmacological Activities ◽  
Pharmacological Studies ◽  
Iris Germanica ◽  
Safety Studies ◽  
History Of ◽  
Therapeutic Activities

Abstract Objectives Iris germanica L. is a medicinal plant, which has a long history of uses, mainly in medieval Persia and many places worldwide for the management of a wide variety of diseases. In this study, we aimed to review ethnopharmacological applications in addition to phytochemical and pharmacological properties of I. germanica. Key findings Ethnomedical uses of I. germanica have been reported from many countries such as China, Pakistan, India, Iran and Turkey. The medicinal part of I. germanica is the rhizome and the roots. Based on phytochemical investigations, different bioactive compounds, including flavonoids, triterpenes, sterols, phenolics, ceramides and benzoquinones, have been identified in its medicinal parts. Current pharmacological studies represent that the plant possesses several biological and therapeutic effects, including neuroprotective, hypoglycaemic, hypolipidaemic, antimicrobial, antioxidant, antiproliferative, anti-inflammatory, antiplasmodial, antifungal, immunomodulatory, cytotoxic and antimutagenic effects. Summary Although the majority of preclinical studies reported various pharmacological activities of this plant, however, sufficient clinical trials are not currently available. Therefore, to draw a definitive conclusion about the efficacy and therapeutic activities of I. germanica and its bioactive compounds, further clinical and experimental studies are required. Moreover, it is necessary to focus on the pharmacokinetic and safety studies on the extracts of I. germanica.

scholarly journals Documentation of Indigenous Knowledge on Folk Medicine in Doddakavalande Doddakavalande Hobli, Nanjangud Taluk of Mysore District, Karnataka

2020 ◽  
Vol 10 (1) ◽  
pp. 39-47
Author(s):  
M Nagalakshmi ◽  
S Rashmi
Keyword(s):  
Medicinal Plants ◽  
Indigenous Knowledge ◽  
Traditional Knowledge ◽  
Plant Species ◽  
Folk Medicine ◽  
Traditional Healers ◽  
Drug Formulation ◽  
Ethnobotanical Survey ◽  
Traditional Medicines ◽  
Herbal Formulations

An ethnobotanical survey was conducted to collect information from traditional healers on the use of herbal medicine in Doddakavalande Hobli, Nanjangud taluk of Mysore District. The indigenous knowledge of local healers was documented through questionnaire and personal interviews. In the present study, about 19 respondents of age group between 50 to 89 yrs gave information of traditional medicines used to cure different ailments. Of about 35 plant species belonging to 26 families were used for the treatment of human ailments. In which family Fabaceae and Polygonaceae contained 3 plant species, followed by Acanthaceae, Amaranthaceae, Apocynaceae, Cucurbitaceae, Poaceae contained 2 species each, and the rest of the families Amaryllidaceae, Anacardiaceae, Apiaceae, Aristolochiaceae, Asteraceae, Cleastraceae, Crassulaceae, Lamiaceae, Lecythidaceae,  Meliaceae,  Olaceae, Phylanthaceae, Piperaceae,  Plumbaginaceae, Poaceae, Polygonaceae, Rutaceae,  Smilacaceae, Solanaceae,  Styracaceae and Zingiberaceae. Habit wise analysis of medicinal plant species used indicated that herbs (19 species) were the most preferred life form followed by trees (8 species), shrubs (5 species) and climbers (3 species) for drug formulation. Herbal formulations were administrated either internally or applied externally depending on the type of ailment. Local people in the study area possess traditional knowledge of medicinal plants to treat various human ailments, therefore it is necessary to preserve the indigenous knowledge on traditional medicines by proper documentation, identification of plant species used, and herbal preparation. Keywords: Ethnobotany, Traditional knowledge, Medicinal plants, Mysore district.

scholarly journals Pemanfaatan Tumbuhan Obat Masyarakat Marind yang Bermukim di Taman Nasional Wasur, Merauke

2018 ◽  
Vol 1 (2) ◽  
pp. 58-64
Author(s):  
Dwi Haryanto ◽  
Rosye H.R. Tanjung ◽  
Konstantina M.B. Kameubun
Keyword(s):  
Medicinal Plants ◽  
Literature Review ◽  
Medicinal Plant ◽  
Key Words ◽  
Plant Species ◽  
National Park ◽  
Medicinal Plant Species ◽  
Root Bark ◽  
Plant Leaf ◽  
Ipomoea Triloba

Study on the used of medicinal plants by Marind people who lived at Wasur National Park, Merauke was conducted by using descriptive methods which include observation, interview, documentation, literature review techniques, as well as  emic and ethic approaches. During the study there were 46 species which belong to 26 families plants found as medicinal plants used by Marind people to cure about 30 diseases. Among 46 species, there were 7 potential medicinal plant species which known  and used by most Marind people. The seven potential medicinal plant species were Ipomoea triloba L., Bauhinia sp., Pittosporum sp., Kingiodendron platycarpum Bent., Sophora tool mentosa L.Cyrtandra sp., dan Tinopspora disstiflora L. Part of plant used vary from leaf, root, bark, fruit and other part of plant. Compare to other part of plant, leaf was the most common used as traditional medicinal plant. Key words:   traditional medicinal plant, Marind people, Wasur National Park

scholarly journals Mesenchymal Stem Cell-Derived Extracellular Vesicle: A Promising Alternative Therapy for Osteoporosis

2021 ◽  
Vol 22 (23) ◽  
pp. 12750
Author(s):  
Cheng-Hsiu Lu ◽  
Yi-An Chen ◽  
Chien-Chih Ke ◽  
Ren-Shyan Liu
Keyword(s):  
Stem Cells ◽  
Therapeutic Potential ◽  
Large Population ◽  
Alternative Therapy ◽  
Osteoporosis Treatment ◽  
Extracellular Vesicle ◽  
Therapeutic Effects ◽  
Promising Alternative ◽  
Treatment Of Osteoporosis ◽  
Therapeutic Applications

Osteoporosis is the chronic metabolic bone disease caused by the disturbance of bone remodeling due to the imbalance of osteogenesis and osteoclastogenesis. A large population suffers from osteoporosis, and most of them are postmenopausal women or older people. To date, bisphosphonates are the main therapeutic agents in the treatment of osteoporosis. However, limited therapeutic effects with diverse side effects caused by bisphosphonates hindered the therapeutic applications and decreased the quality of life. Therefore, an alternative therapy for osteoporosis is still needed. Stem cells, especially mesenchymal stem cells, have been shown as a promising medication for numerous human diseases including many refractory diseases. Recently, researchers found that the extracellular vesicles derived from these stem cells possessed the similar therapeutic potential to that of parental cells. To date, a number of studies demonstrated the therapeutic applications of exogenous MSC-EVs for the treatment of osteoporosis. In this article, we reviewed the basic back ground of EVs, the cargo and therapeutic potential of MSC-EVs, and strategies of engineering of MSC-EVs for osteoporosis treatment.

Ethnobotanical Survey of Medicinal Plants Used to Treat Cardiovascular Disorders in Ghasemloo Valley of Urmia City.

2021 ◽  
Vol 19 ◽  
Author(s):  
Gholam Basati ◽  
Saber Abbaszadeh ◽  
Afshin Hasanvand ◽  
Parastoo Baharvand
Keyword(s):  
Cardiovascular Diseases ◽  
Medicinal Plants ◽  
Plant Species ◽  
Blood Cholesterol ◽  
Therapeutic Effects ◽  
Clinical Effects ◽  
Cardiovascular Disorders ◽  
Indigenous Plants ◽  
Cardiovascular Research ◽  
Traditional Drug

Aims: Many pharmacutical plants belonged to this region are used as the traditional drug by traditional physicians of the Urmia city in order to treat signs of disorders and cardiovescular system diseases. Background: The Ghasemloo valley located in the Urmia city is one of the typical areas in the northwestern Iran and includes many pharmacutical and plant species. Objective: Many pharmacutical plants belonged to this region are used as the traditional drug by traditional physicians of the Urmia city in order to treat signs of disorders and cardiovescular system diseases. Method: Study was performed among 35 grocers in the Urmia city to identify effective and famous pharmacutical plants in treatment of cardiovescular and related diseases. Firstly a complete list of Urmia grocers was prepared from the Food and Drug Administrator of the Urmia University of Medical Sciences. The direct observation and interview alongside collecting herbarium samples of usual and effective indigenous medicinal plants were used to identify disorders and different signs of cardiovascular diseases. Questionnaires included personal information of grocers and they completed indigenous plants list containing information including the plant local name, the used organ, method of use, and the traditional therapeutic effect. Herbarium samples mentioned in the questionnaire were collected from the region and sent to the Jahad-e-Keshavarzi Research Centers and the Agriculture Faculty of Urmia university to determine the genus and species. After identifying and confirming the plant species, data related to the plant and results of cardiovascular research conducted on them were collected and recorded with reference to valid scientific sites. Data were enterred into the Excel 2010 program and then analyzed. Results : 60 medicinal plants of 26 families in Urmia were identified as effective in treatment of cardiovascular diseases from interviews and questionnaires; some plants mentioned in this study had known traditional therapeutic effects on cardiovascular disorders in the literature and some were identified with new effects. Results showed that the most therapeutic effects in cardiovascular diseases belonged to families Rosaceae (15%), Fabaceae (13%), Asteraceae (13%), and Apiaceae (10%). The most used organs of plants were the leave (23%) and fruit (19%). Plants were used mainly as infusion (68%) in the traditional method. Most plants of this study were used to treat the blood cholesterol (29%), hypertension (9%), the blood coagulation, prevention of bleeding (9%), and decrease in the abdominal fat (9%). Conclusion: Some herbs introduced in this study have new therapeutic effects introduced for the first time. It is necessary to study therapeutic effects of indigenous plants presented in this research in order to prove studied and mentioned therapeutic effects and to provide study field for researchers in relation to identifying effective substances and studying claimed clinical effects of these plants on different cardiovascular diseases.

Ethnobotanical Study of Traditional Medicinal Plants used as Anti-Psoriatic in Rajasthan

2016 ◽  
Vol 23 (4) ◽  
pp. 225-232
Author(s):  
M. Singhadiya ◽  
Isha Pandey ◽  
Vinod Maina ◽  
R. Pandey ◽  
Peddy Harikrishna
Keyword(s):  
Medicinal Plants ◽  
Research And Development ◽  
Traditional Knowledge ◽  
Indigenous People ◽  
Plant Species ◽  
New Drugs ◽  
Ethnobotanical Study ◽  
Plant Parts ◽  
Traditional Medicinal Plants ◽  
Ethnomedicinal Plant

The present study deals with 26 ethnomedicinal plant species belonging to 17 families used as antipsoriatic by the indigenous people in Rajasthan. The study also deals with types of Psoriasis, plant name, local name, family name, plant parts and mode in the treatment of psoriasis. The present study also gathered important information about traditional knowledge and the need to document, research and development of new drugs to fight against Psoriasis disease in Rajasthan in particular and India as a whole.

The Potential of Medicinal Plants as Galactagogue in Indonesia: A Review from Medical Perspective

2021 ◽  
Vol 14 (3) ◽  
pp. 1595-1612
Author(s):  
Astrid Feinisa Khairani ◽  
Teuku Muhammad Adzdzikri ◽  
Shafa Tasya Menggala ◽  
Muhammad Hasan Bashari ◽  
Enny Rohmawaty ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Breast Milk ◽  
Medicinal Plants ◽  
Literature Review ◽  
Common Factor ◽  
World Health ◽  
Efficacy And Safety ◽  
Positive Effects ◽  
The World ◽  
Medical Perspective

The World Health Assembly's target in exclusive breastfeeding has not been achieved. The most common factor contributing to this problem is the perceived insufficient production of breast milk, leading to the inability to give breastmilk to her child. Milk production can be increased using some ways, such as herbal galactagogue. This article aimed to review the effectiveness of some medicinal plants as galactagogues. This study uses a literature review approach by using several sources selected based on the criteria that have been set by researchers. Based on thirteen literature, herbs reviewed in this article showed positive effects as a galactagogue. Evidence regarding its efficacy and safety is scarce. Additionally, few clinical trials exist to justify its effectiveness. Further clinical trials are needed to support these findings.

scholarly journals Ethnobotanical characterization of medicinal plants used in Kisantu and Mbanza-Ngungu territories, Kongo-Central Province in DR Congo

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Kibungu Kembelo Pathy ◽  
Nzuki Bakwaye Flavien ◽  
Belesi Katula Honoré ◽  
Wouter Vanhove ◽  
Patrick Van Damme
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Plant Species ◽  
Therapeutic Potential ◽  
Social Groups ◽  
Central Province ◽  
Dr Congo ◽  
Plant Knowledge ◽  
Medicinal Plant Knowledge ◽  
Cultural Similarity

Abstract Background The phytotherapeutic knowledge of the Kongo people in the territories of Kisantu and Mbanza-Ngungu in Kongo-Central Province (DR Congo) is rapidly eroding. To document the remaining knowledge, we conducted an ethnobotanical survey on the most important medicinal plant species and diseases treated with them, as well as plants with therapeutic potential. We also checked for the cultural similarity in medicinal plant knowledge between the two territories and how knowledge about Kongo medicinal plants differs between different social groups. Methods From June 2017 until February 2018 and from February 2019 until April 2019, we conducted a survey with 188 phytotherapists, selected using the snowball method and surveyed using semi-structured interviews. Voucher specimens were taken for identification. Ethnobotanical data were analyzed using medicinal use value (UVs), informant agreement ratio (IARs), informant consensus factor (ICF), and species therapeutic potential (STP). Rahman’s similarity index was used for ethno-cultural comparison of medicinal plant knowledge between the two communities. Medicinal knowledge between different social groups was analyzed using non-parametric tests and Poisson regression. Results A total of 231 plants (i.e., 227 botanical species, representing 192 genera and 79 families) were reportedly used to treat 103 diseases. Most abundant taxa were reported for the Fabaceae family (including 11.9% of species and 10.9% of genera). Most reported species (45.0%) were from anthropized areas. Leaves (39.4%), herbs (37.1%), decoction (41.7%), and oral ingestion (72%) were the most frequently cited plant part, botanical form, preparation, and administration method, respectively. Four of all inventoried species showed high UVS (> 0.05), whereas eight had an IAR of one. According to ICF, 31 diseases were mentioned. Highest ICF (≥ 0.4) was observed for hemorrhoids (0.44), amoebiasis (0.43), and itchy rash (0.42). Fifty-four plant species were identified as likely possessing an interesting therapeutic potential. Low ethno-cultural similarity in medicinal knowledge (RSI = 16.6%) was found between the two territories. Analysis of the Kongo medicinal plant knowledge showed that the mean number of reported species and diseases vary considerably depending on gender, type, and residence of therapists (P < 0.05). Conclusion Results prove that the Kongo phytopharmacopeia makes use of interesting medicinal plant species that could be further studied for conservation and pharmacological applications.

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