scholarly journals Lung cancer mortality due to delayed treatment: Literature review

2021 ◽  
Vol 60 (2) ◽  
pp. 36-38
Author(s):  
B. А. Abdurakhmanov ◽  
Z. К. Avizovа
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Survival Rates ◽  
Lung Cancer Mortality ◽  
Qualitative Assessment ◽  
Scientific Publications ◽  
Delayed Treatment ◽  
Incidence And Mortality ◽  
The Impact ◽  
Delay In Treatment

Lung cancer is still leading in the structure of cancer incidence and mortality worldwide. Delay in appropriate treatment increases the probability of death from this disease. Purpose: to study foreign scientific publications of recent years on the mortality from lung cancer due to delayed treatment. Results: The analysis of global literature for 2010-2020 shows that any delay in lung cancer treatment after establishing the diagnosis reduces the survival rates. Recent studies provide a qualitative assessment of the effect of delay in treatment on cancer mortality for prioritization and modeling. The indications for surgery, systemic treatment, and radiation therapy in seven types of cancer, including lung cancer, evidence a significant association between delay in treatment and increased mortality. The researchers believe that early diagnostics increase the treatment efficacy. Conclusion: Analyzing the barriers to timely treatment for lung cancer can help clarify and assess the impact of delayed treatment on survival. Policies designed to minimize delays in treatment can improve survival outcomes.

scholarly journals Lung cancer mortality due to delayed treatment: Literature review

2021 ◽  
Vol 60 (2) ◽  
pp. 36-38
Author(s):  
B. А. Abdurakhmanov ◽  
Z. К. Avizovа
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Survival Rates ◽  
Lung Cancer Mortality ◽  
Qualitative Assessment ◽  
Scientific Publications ◽  
Delayed Treatment ◽  
Incidence And Mortality ◽  
The Impact ◽  
Delay In Treatment

Relevance: Lung cancer is still leading in the structure of cancer incidence and mortality worldwide. Delay in appropriate treatment increases the probability of death from this disease. Purpose: to study foreign scientific publications of recent years on the mortality from lung cancer due to delayed treatment. Results: The analysis of global literature for 2010- 2020 shows that any delay in lung cancer treatment after establishing the diagnoses reduces the survival rates. Recent studies provide a qualitative assessment of the effect of delay in treatment on cancer mortality for prioritization and modeling. The indications for surgery, systemic treatment, and radiation therapy in seven types of cancer, including lung cancer, evidence a significant association between delay in treatment and increased mortality. The researchers believe that early diagnostics increase the treatment efficacy. Conclusion: Analyzing the barriers to timely treatment for lung cancer can help clarify and assess the impact of delayed treatment on survival. Policies designed to minimize delays in treatment can improve survival outcomes.

scholarly journals Exploring the impact of screening with low-dose CT on lung cancer mortality in mild to moderate COPD patients: A pilot study

2013 ◽  
Vol 107 (5) ◽  
pp. 702-707 ◽  
Author(s):  
Juan P. de-Torres ◽  
Ciro Casanova ◽  
Jose M. Marín ◽  
Jorge Zagaceta ◽  
Ana B. Alcaide ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pilot Study ◽  
Cancer Mortality ◽  
Low Dose ◽  
Lung Cancer Mortality ◽  
Low Dose Ct ◽  
Copd Patients ◽  
The Impact

scholarly journals The impact of atmospheric particulate matter on cancer incidence and mortality in the city of São Paulo, Brazil

2012 ◽  
Vol 28 (9) ◽  
pp. 1737-1748 ◽  
Author(s):  
Yoshio Yanagi ◽  
João Vicente de Assunção ◽  
Ligia Vizeu Barrozo
Keyword(s):  
Particulate Matter ◽  
Cancer Incidence ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Sao Paulo ◽  
Atmospheric Particulate Matter ◽  
São Paulo ◽  
Incidence And Mortality ◽  
The Impact ◽  
The City

This study aimed to verify the impact of inhalable particulate matter (PM10) on cancer incidence and mortality in the city of São Paulo, Brazil. Statistical techniques were used to investigate the relationship between PM10 on cancer incidence and mortality in selected districts. For some types of cancer (skin, lung, thyroid, larynx, and bladder) and some periods, the correlation coefficients ranged from 0.60 to 0.80 for incidence. Lung cancer mortality showed more correlations during the overall period. Spatial analysis showed that districts distant from the city center showed higher than expected relative risk, depending on the type of cancer. According to the study, urban PM10 can contribute to increased incidence of some cancers and may also contribute to increased cancer mortality. The results highlight the need to adopt measures to reduce atmospheric PM10 levels and the importance of their continuous monitoring.

scholarly journals The impact of certification of general thoracic surgeons on lung cancer mortality: a survey by The Japanese Association for Thoracic Surgery

2016 ◽  
Vol 49 (5) ◽  
pp. e134-e140 ◽  
Author(s):  
Takeshi Nagayasu ◽  
Shuntaro Sato ◽  
Hiroshi Yamamoto ◽  
Naoya Yamasaki ◽  
Tomoshi Tsuchiya ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Thoracic Surgery ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Japanese Association ◽  
The Impact

scholarly journals Assessing Progress in Reducing the Burden of Cancer Mortality, 1985-2005

2014 ◽  
Vol 32 (5) ◽  
pp. 444-448 ◽  
Author(s):  
Samir Soneji ◽  
Hiram Beltrán-Sánchez ◽  
Harold C. Sox
Keyword(s):  
Lung Cancer ◽  
Cancer Incidence ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Mortality Rates ◽  
Years Of Life Lost ◽  
Average Person ◽  
Two Factors ◽  
The Impact ◽  
Cvd Mortality

Purpose Measuring the effect of cancer interventions must take into account rising cancer incidence now that people live longer because of declines in mortality from cardiovascular disease (CVD). Cancer mortality rates in the population do not accomplish this objective. We sought a measure that would reveal the effects of changing mortality rates from other diseases. Methods We obtained annual breast, colorectal, lung, and prostate cancer mortality rates from the Surveillance, Epidemiology, and End Results registries; we obtained noncancer mortality rates from national death certificates, 1975 to 2005. We used life-table methods to calculate the burden of cancer mortality as the average person-years of life lost (PYLL) as a result of cancer (cancer-specific PYLL) and quantify individual—and perhaps offsetting—contributions of the two factors that affect cancer-specific PYLL: mortality rates as a result of cancer and other-cause mortality. Results Falling cancer mortality rates reduced the burden of mortality from leading cancers, but increasing cancer incidence as a result of decreasing other-cause mortality rates partially offset this progress. Between 1985 and 1989 and between 2000 and 2004, the burden of lung cancer in males declined by 0.1 year of life lost. This decline reflects the sum of two effects: decreasing lung cancer mortality rates that reduced the average burden of lung cancer mortality by 0.33 years of life lost and declining other-cause mortality rates that raised it by 0.23 years. Other common cancers showed similar patterns. Conclusion By using a measure that accounts for increased cancer incidence as a result of improvements in CVD mortality, we find that prior assessments have underestimated the impact of cancer interventions.

scholarly journals Lung Cancer Mortality Trends in a Brazilian City with a Long History of Asbestos Consumption

2019 ◽  
Vol 16 (14) ◽  
pp. 2548 ◽  
Author(s):  
Gisele Aparecida Fernandes ◽  
Eduardo Algranti ◽  
Gleice Margarete de Souza Conceição ◽  
Victor Wünsch Filho ◽  
Tatiana Natasha Toporcov
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Asbestos Exposure ◽  
Lung Cancer Mortality ◽  
Epidemiological Studies ◽  
Sao Paulo ◽  
São Paulo ◽  
Mortality Trends ◽  
Risk Of Death ◽  
Incidence And Mortality

There are scarce epidemiological studies on lung cancer mortality in areas exposed to asbestos in developing countries. We compared the rates and trends in mortality from lung cancer between 1980 and 2016 in a municipality that made extensive use of asbestos, Osasco, with rates from a referent municipality with lower asbestos exposure and with the rates for the State of São Paulo. We retrieved death records for cases of lung cancer (ICD-9 C162) (ICD-10 C33 C34) from 1980 to 2016 in adults aged 60 years and older. The join point regression and age-period-cohort models were fitted to the data. Among men, there was an increasing trend in lung cancer mortality in Osasco of 0.7% (CI: 0.1; 1.3) in contrast to a mean annual decrease for Sorocaba of -1.5% (CI: −2.4; −0.6) and a stable average trend for São Paulo of -0.1 (IC: −0.3; 0.1). Similar increasing trends were seen in women. The age-period-cohort model showed an increase in the risk of death from 1996 in Osasco and a reduction for Sorocaba and São Paulo State during the same period. Our results point to a need for a special monitoring regarding lung cancer incidence and mortality in areas with higher asbestos exposure.

scholarly journals Safety and Effectiveness of Lung Cancer Screening Using Low-dose Computed Tomography Scan in High-risk Individuals: A Comprehensive Review

2021 ◽  
Author(s):  
Sara Mohamadi ◽  
Rajabali Daroudi ◽  
Mohamadreza Mobinizadeh
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Cancer Screening ◽  
High Risk ◽  
Cancer Mortality ◽  
Lung Cancer Screening ◽  
Lung Cancer Mortality ◽  
Comprehensive Review ◽  
Incidence And Mortality ◽  
Technical Specifications

Context: Lung cancer is the most important cause of cancer mortality. Given the incidence and mortality of this disease, the implementation of preventive interventions is necessary. Objectives: The present study investigated the effectiveness of one of the most important interventions of lung cancer screening with lowdose computed tomography (LDCT) in high-risk individuals. Evidence Acquisition: The present study was an applied study performed as a comprehensive review. For the assessment of safety, studies on the technical specifications of computed tomography scans and issues related to the safety of applying this device were searched using keywords in medical databases. For the evaluation of clinical effectiveness, a comprehensive review of health technology assessment studies, systematic review studies, and screening guidelines was performed. Results: Based on 15 studies extracted for the safety issue, the diagnosis of harmless tumors, false positives cases and Unnecessary invasive complementary interventions, and possible negative effects of radiation exposure are discussable safety issues. Based on the synthesis of 16 studies on effectiveness, lung cancer screening intervention using LDCT was determined to reduce lung cancer mortality by 15 - 20% and mortality from other causes by 0 - 6%. Additionally, the incidence of this disease in its upper stages decreases significantly. Conclusions: Lung cancer screening using LDCT does not threaten the health of individuals seriously and, in comparison to nonintervention is more clinically effective and will lead to a statistically significant reduction in lung cancer mortality and increase in the timely diagnosis of this disease.  

scholarly journals Socioeconomic disparities in cancer incidence and mortality in England and the impact of age-at-diagnosis on cancer mortality

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0253854
Author(s):  
Ayşe Arık ◽  
Erengul Dodd ◽  
Andrew Cairns ◽  
George Streftaris
Keyword(s):  
Lung Cancer ◽  
Cancer Diagnosis ◽  
Cancer Incidence ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Socioeconomic Disparities ◽  
Morbidity And Mortality ◽  
Cancer Morbidity ◽  
The Impact ◽  
Female Lung Cancer

Background We identify socioeconomic disparities by region in cancer morbidity and mortality in England for all-cancer and type-specific cancers, and use incidence data to quantify the impact of cancer diagnosis delays on cancer deaths between 2001–2016. Methods and findings We obtain population cancer morbidity and mortality rates at various age, year, gender, deprivation, and region levels based on a Bayesian approach. A significant increase in type-specific cancer deaths, which can also vary among regions, is shown as a result of delay in cancer diagnoses. Our analysis suggests increase of 7.75% (7.42% to 8.25%) in female lung cancer mortality in London, as an impact of 12-month delay in cancer diagnosis, and a 3.39% (3.29% to 3.48%) increase in male lung cancer mortality across all regions. The same delay can cause a 23.56% (23.09% to 24.30%) increase in male bowel cancer mortality. Furthermore, for all-cancer mortality, the highest increase in deprivation gap happened in the East Midlands, from 199 (186 to 212) in 2001, to 239 (224 to 252) in 2016 for males, and from 114 (107 to 121) to 163 (155 to 171) for females. Also, for female lung cancer, the deprivation gap has widened with the highest change in the North West, e.g. for incidence from 180 (172 to 188) to 272 (261 to 282), whereas it has narrowed for prostate cancer incidence with the biggest reduction in the South West from 165 (139 to 190) in 2001 to 95 (72 to 117) in 2016. Conclusions The analysis reveals considerable disparities in all-cancer and some type-specific cancers with respect to socioeconomic status. Furthermore, a significant increase in cancer deaths is shown as a result of delays in cancer diagnoses which can be linked to concerns about the effect of delay in cancer screening and diagnosis during the COVID-19 pandemic. Public health interventions at regional and deprivation level can contribute to prevention of cancer deaths.

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