Review on Nanotechnology and its utilization in Pharmaceuticals

2021 ◽  
pp. 319-322
Author(s):  
Kiran Patole ◽  
Anil Danane ◽  
Amit Nikam ◽  
Anuja Patil
Keyword(s):  
Drug Delivery ◽  
Pharmaceutical Industry ◽  
Molecular Biology ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Medication Delivery ◽  
Traditional Drug ◽  
Pharmaceutical Nanotechnology

Nanotechnology is the study of tiny structures ranging in size from 0.1 to 100 nanometers. It includes biophysics, molecular biology, and bioengineering, as well as medical subspecialties such as cardiology, ophthalmology, endocrinology, oncology, and immunology. Pharmaceutical Nanotechnology combines the methods and ideas of nanoscience and nanomedicine with pharmacy to create novel medication delivery systems that transcend the limitations of traditional drug delivery systems. The purpose of this article is to provide an overview of nanotechnology and its uses in the pharmaceutical industry.

Carbon Nanotubes, Quantum Dots and Dendrimers as Potential Nanodevices for Nanotechnology Drug Delivery Systems

2013 ◽  
Vol 6 (3) ◽  
pp. 2113-2124
Author(s):  
Prashant Malik ◽  
Neha Gulati ◽  
Raj Kaur Malik ◽  
Upendra Nagaich
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Quantum Dots ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Atomic Scale ◽  
Sustained Drug Delivery ◽  
Pharmaceutical Nanotechnology ◽  
Conventional Device

Nanotechnology deal with the particle size in nanometers. Nanotechnology is ranging from extensions of conventional device physics to completely new approaches based upon molecular self assembly, from developing new materials with dimensions on the nanoscale to direct control of matter on the atomic scale. In nanotechnology mainly three types of nanodevices are described: carbon nanotubes, quantum dots and dendrimers. It is a recent technique used as small size particles to treat many diseases like cancer, gene therapy and used as diagnostics. Nanotechnology used to formulate targeted, controlled and sustained drug delivery systems. Pharmaceutical nanotechnology embraces applications of nanoscience to pharmacy as nanomaterials and as devices like drug delivery, diagnostic, imaging and biosensor materials. Pharmaceutical nanotechnology has provided more fine tuned diagnosis and focused treatment of disease at a molecular level.    

scholarly journals Bacteriophage-based tools: recent advances and novel applications

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 2782 ◽  
Author(s):  
Lisa O'Sullivan ◽  
Colin Buttimer ◽  
Olivia McAuliffe ◽  
Declan Bolton ◽  
Aidan Coffey
Keyword(s):  
Drug Delivery ◽  
Drug Discovery ◽  
Molecular Biology ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Bacterial Populations ◽  
Recent Advances ◽  
Novel Applications ◽  
Novel Drug ◽  
Bacterial Control

Bacteriophages (phages) are viruses that infect bacterial hosts, and since their discovery over a century ago they have been primarily exploited to control bacterial populations and to serve as tools in molecular biology. In this commentary, we highlight recent diverse advances in the field of phage research, going beyond bacterial control using whole phage, to areas including biocontrol using phage-derived enzybiotics, diagnostics, drug discovery, novel drug delivery systems and bionanotechnology.

Cancer Therapy Based on Smart Drug Delivery with Advanced Nanoparticles

2019 ◽  
Vol 19 (6) ◽  
pp. 720-730 ◽  
Author(s):  
Xiangqi Kong ◽  
Yi Liu ◽  
Xueyan Huang ◽  
Shuai Huang ◽  
Feng Gao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Side Effect ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Molecular Imaging Probes ◽  
Imaging Probes ◽  
Traditional Drug ◽  
Smart Drug ◽  
Smart Drug Delivery ◽  
Better Than

Background: Cancer, as one of the most dangerous disease, causes millions of deaths every year. The main reason is the absence of an effective and thorough treatment. Drug delivery systems have significantly reduced the side-effect of chemotherapy. Combined with nanotechnology, smart drug delivery systems including many different nanoparticles can reduce the side-effect of chemotherapy better than traditional drug delivery systems. Methods: In this article, we will describe in detail the different kinds of nanoparticles and their mechanisms emphasizing the triggering factors in drug delivery. Besides, the application of smart drug delivery systems in imaging will be introduced. Results: Combined with nanotechnology, smart drug delivery systems including many different nanoparticles can reduce the side-effect of chemotherapy better than traditional drug delivery systems. Conclusion: Despite considerable progress in nanoparticle research over the past decade, such as smart drug delivery systems for the treatment of cancer, molecular imaging probes and the like. The range of nanoparticles used in multifunction systems for imaging and drug delivery continues to grow and we expect this dilatation to continue. But to make nanoparticles truly a series of clinical products to complement and replace current tools, constant exploration efforts and time are required. Overall, the future looks really bright.

An Overview of the Recent Developments and Patents in The Field of Pharmaceutical Nanotechnology

2020 ◽  
Vol 14 ◽  
Author(s):  
Deepika Purohit ◽  
Deeksha Manchanda ◽  
Manish ◽  
Jyoti Rathi ◽  
Ravinder Verma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Carbon Nanomaterials ◽  
Drug Carriers ◽  
Delivery Systems ◽  
Correlation Spectroscopy ◽  
Colloidal System ◽  
The Novel ◽  
Pharmaceutical Nanotechnology ◽  
Novel Drug

Background: Compared to traditional dosage methods, the novel drug delivery systems (NDDS) provide various advantages. In the last few years, tremendous focus has been given to work focused on the novel drug delivery methods for small and large molecular drug carriers utilizing particulate drug delivery systems as well. It is evident from last decade as seen in number of patents cited in this field that the technology has evolved tremendously. Objective: Drug carriers utilized by this novel technology includes liposomes, dendrimers, polymeric nanoparticles, magnetic nanoparticles, solid lipid nanoparticles, carbon nanomaterials. Various forms of polymers have been used in the production of nanocarriers. Methods: Nanocarriers are colloidal system varying in size from 10 to 1000 nm. This technology now used to identify, manage and monitor numerous diseases and physical methods to alter and enhance the pharmacokinetic and pharmacodynamic properties of specific types of drug molecules. Results: Nanoparticles can be formulated by a number of techniques including ionic gelation, cross-linking, coacervation/precipitation, nanoprecipitation, spray drying, emulsion- droplet coalescence, nano sonication techniques etc. Several methods are used with which these nanoparticles can be characterized. These methods include nuclear magnetic resonance, optical microscopy, atomic force microscopy, photon correlation spectroscopy and electron microscopy, surface charge, in-vitro drug release, etc. Conclusion: In the present review, authors have tried to summarize the recent advances in the field of pharmaceutical nanotechnology and also focuses on the application and new patents in the area related to NDDS.

scholarly journals Special Issue: Advanced Materials in Drug Release and Drug Delivery Systems

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 1042
Author(s):  
Katarzyna Winnicka
Keyword(s):  
Drug Delivery ◽  
Pharmaceutical Industry ◽  
Drug Release ◽  
Drug Delivery Systems ◽  
Pharmaceutical Formulations ◽  
Delivery Systems ◽  
Advanced Materials ◽  
Special Issue ◽  
New Drug ◽  
Drug Molecules

Development of new drug molecules is costly and requires longitudinal, wide-ranging studies; therefore, designing advanced pharmaceutical formulations for existing and well-known drugs seems to be an attractive device for the pharmaceutical industry [...]

scholarly journals Bioinspired Silica Offers a Novel, Green, and Biocompatible Alternative to Traditional Drug Delivery Systems

2016 ◽  
Vol 2 (9) ◽  
pp. 1493-1503 ◽  
Author(s):  
Scott Davidson ◽  
Dimitrios A. Lamprou ◽  
Andrew J. Urquhart ◽  
M. Helen Grant ◽  
Siddharth V. Patwardhan
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Traditional Drug

scholarly journals Nanoparticle-based drug delivery systems: What can they really do in vivo?

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 681 ◽  
Author(s):  
Yi-Feng Wang ◽  
Lu Liu ◽  
Xue Xue ◽  
Xing-Jie Liang
Keyword(s):  
Drug Delivery ◽  
Blood Circulation ◽  
Drug Delivery Systems ◽  
Basic Research ◽  
Delivery Systems ◽  
Multi Drug Resistance ◽  
The Past ◽  
Controllable Release ◽  
Traditional Drug

In the past few decades, there has been explosive growth in the construction of nanoparticle-based drug delivery systems (NDDSs), namely nanomedicines, owing to their unique properties compared with traditional drug formulations. However, because of a variety of challenges, few nanomedicines are on sale in the market or undergoing clinical trial at present. Thus, it is essential to look back and re-evaluate what these NDDSs can really do in vivo, why nanomedicines are regarded as potential candidates for next-generation drugs, and what the future of nanomedicine is. Here, we focus mainly on the properties of NDDSs that extend blood circulation, enhance penetration into deep tumor tissue, enable controllable release of the payload into the cytoplasm, and overcome multi-drug resistance. We further discuss how to promote the translation of nanomedicines into reality. This review may help to identify the functions of NDDSs that are really necessary before they are designed and to reduce the gap between basic research and clinical application.

scholarly journals The role of pharmaceutical nanotechnology in the time of COVID-19 pandemic

2020 ◽  
Vol 15 (16) ◽  
pp. 1571-1582
Author(s):  
Lígia N de M Ribeiro ◽  
Belchiolina B Fonseca
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
In Vitro Toxicity ◽  
Clinical Use ◽  
Therapeutic Action ◽  
High Toxicity ◽  
Pharmaceutical Nanotechnology

There is no effective therapy against COVID-19 available so far. In the last months, different drugs have been tested as potential treatments for COVID-19, exhibiting high toxicity and low efficacy. Therefore, nanotechnology can be applied to improve the therapeutic action and minimize the toxicity of loaded drugs. In this review, we summarized the drugs tested as COVID-19 treatment and the advantages of antiviral nanostructured drug-delivery systems. Such systems have demonstrated low in vitro toxicity with better in vitro antiviral activity than free drugs. We believe that this approach should inspire novel nanostructured drug-delivery systems developments to find efficient COVID-19 treatments. Here, we discuss the remaining challenges for such promising nanosystems to be approved for clinical use.

Enhancing the Therapeutic Efficacy of Flavonoids as Anticancer Drugs Through Novel Drug Delivery Systems

2021 ◽  
pp. 207-229
Author(s):  
Anamika Basu
Keyword(s):  
Drug Delivery ◽  
Therapeutic Efficacy ◽  
Drug Delivery Systems ◽  
Fruits And Vegetables ◽  
Delivery Systems ◽  
Inorganic Nanoparticles ◽  
Therapeutic Uses ◽  
Different Types ◽  
Traditional Drug ◽  
Novel Drug

Flavonoids are a group of heterocyclic compounds that are well-known for their anti-cancer activity. Fruits and vegetables are the main dietary sources of flavonoids. Several mechanisms have been proposed for the effect of flavonoids to combat cancer. But before considering the flavonoids as chemotherapeutic drugs for cancer, a number of problems still need to be addressed before their therapeutic uses. Solubility may play a major role in the therapeutic efficacy of flavonoids. Bioavailability of flavonoids are also affected by several other factors. Nanotechnology is the most efficient tool to solve the problems of solubility, stability, and oral bioavailability. Nanotechnology-based drug delivery has several benefits compared to the traditional drug delivery systems. Different types of nano delivery systems are used for producing nanomedicines such as lipid-based nanomedicines, polymer-based nanomedicines, and inorganic nanoparticles. Different types of flavonoids encapsulated nanoparticles have been developed to improve their effectiveness against different types of cancer.

Sign in / Sign up

Export Citation Format

Share Document