An evaluation of Mucormycosis, Outburst

2021 ◽  
pp. 591-593
Author(s):  
Sholly. CK
Keyword(s):  
Fungal Infection ◽  
Sudden Change ◽  
Health Issues ◽  
Rotten Wood ◽  
Airway Mucosa ◽  
Animal Dung ◽  
Life Saving ◽  
Life Threatening ◽  
Long Term Ventilation ◽  
Sugar Levels

Black fungus is also known as Mucormycosis, and it is occasional but threatening infection. Black fungus is caused by getting into exposure with fungus spores in the surroundings. It can also form in the skin after the fungus enters through a cut, scrape, burn, or another type of skin trauma. Fungi live in the environment, particularly in soil and decaying organic matter such as leaves, compost piles, rotten wood, particularly in soil, compost, and animal dung. This fungal infection is caused by a type of mould known as 'mucromycetes’. It should be noted that this rare fungal infection affects persons who have health issues or who use drugs that weaken the body's ability to fight the infections. There are different types of mucormycosis Trusted Source, including rhino cerebral (sinus and brain), pulmonary (lung), gastrointestinal, and cutaneous (skin) mucormycosis. The COVID-19 generates a sudden change in the interior environment of the host for the fungus, and the medical treatment administered unknowingly promotes fungal development. COVID-19 causes harm to the airway mucosa and blood vessels. It also causes a rise in serum iron, which is required for the fungus to grow. Broad-spectrum antibiotics not only kill potentially harmful bacteria but also beneficial commensals. Although antifungals such as Voriconazole prevent Aspergillosis, Mucor survives and grows due to a lack of resistance. Long-term ventilation decreases immunity, and there is conjecture that the humidifier water that is delivered along with the oxygen transfers the fungus. It is ubiquitous and found in soil and air and even in the nose and mucus of healthy people. It affects the sinuses, the brain and the lungs and can be life-threatening in diabetic or severely immunocompromised individuals, such as cancer patients or people with HIV/AIDS. Doctors believe mucormycosis, which has an overall mortality rate of 50%, may be being triggered by the use of steroids, a life-saving treatment for severe and critically ill Covid-19 patients. Steroids reduce inflammation in the lungs for Covid-19 and appear to help stop some of the damage that can happen when the body's immune system goes into overdrive to fight off coronavirus. But they also reduce immunity and push up blood sugar levels in both diabetics and non-diabetic Covid-19 patients. It’s thought that this drop in immunity could be triggering these cases of mucormycosis.

Review on Mucormycosis: It is a life Threatening infection

2021 ◽  
pp. 316-318
Author(s):  
S.D. Mankar ◽  
Waditake Poonam ◽  
Prajakta Jejurkar
Keyword(s):  
Fungal Infection ◽  
Organic Waste ◽  
The Body ◽  
Health Issues ◽  
Home Remedies ◽  
Animal Dung ◽  
The World ◽  
Life Threatening ◽  
Ayurvedic Treatment

Mucormycosis, often known as black fungus, is a fungal infection caused by the mucormycetes fungi. Zygomycetes is a class of fungi. Mucormycetes, the fungus that cause mucormycosis, are found all throughout the world, especially in soil and in decaying organic waste like leaves, compost piles, and animal dung. It is not contagious and cannot be passed from one person to another. Mucormycosis (also known as zygomycosis) is a dangerous but uncommon fungal infection caused by a fungus known as mucormycetes. Molds can be found all over the place. Mucormycosis is a fungal infection that primarily affects persons who have health issues or who use medications that reduce the body's capacity to resist infections and illness. Infections are most typically acquired when mould spores are inhaled or, less commonly, when spores enter the body through a cut in the skin. It takes place after COVID-19. Home remedies, such as consuming probiotics, and foods that promote immunity, can help to minimise mucormycosis. The main purpose of this review Related to Mucormycosis is to diminish the growth of Mucormycosis by taking Ayurvedic Treatment.

scholarly journals Myelodysplastic Syndrome Clinically Presenting with the “Classic TTP Pentad”

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Santiago Fabián Moscoso Martínez ◽  
Evelyn Carolina Polanco Jácome ◽  
Elizabeth Guevara ◽  
Vijay Mattoo
Keyword(s):  
Myelodysplastic Syndrome ◽  
Clinical Presentation ◽  
Renal Involvement ◽  
Medical Emergency ◽  
Complete Blood Cell Count ◽  
Blood Cell Count ◽  
Thrombocytopenic Purpura ◽  
Life Saving ◽  
Threatening Condition ◽  
Life Threatening

The clinical presentation of myelodysplastic syndrome (MDS) is not specific. Many patients can be asymptomatic and can be detected only due to an abnormal complete blood cell count (CBC) on routine exam or for other reasons while others can be symptomatic as a consequence of underlying cytopenias. Thrombotic thrombocytopenic purpura (TTP) usually is suspected under the evidence of microangiopathic hemolytic anemia (MAHA) and thrombocytopenia and because it is a life-threatening condition (medical emergency) immediate initiation of plasmapheresis could be life-saving. The following case illustrates an unusual presentation of MDS in a patient who came in to the emergency room with the classic TTP “pentad” of fever, renal involvement, MAHA, mental status changes, and thrombocytopenia. We will focus our discussion in the clinical presentation of this case.

The Role of Psilocybin-Assisted Psychotherapy to Support Patients With Cancer: A Critical Scoping Review of the Research

2021 ◽  
pp. 089801012110390
Author(s):  
Rebecca H. Lehto ◽  
Megan Miller ◽  
Jessica Sender
Keyword(s):  
Mental Health ◽  
Health Issues ◽  
Mushroom Species ◽  
Patients With Cancer ◽  
Existential Suffering ◽  
Vulnerable Patients ◽  
Scoping Literature Review ◽  
Life Threatening ◽  
Self Transcendence

Treatments for addressing psychiatric mental health issues in vulnerable patients with cancer are established. Yet, many patients persist with unrelenting psychological difficulties despite intervention. There is growing interest in the role of psilocybin-assisted psychotherapy for managing treatment-resistant mental health challenges in patients with cancer. Psilocybin is a naturally occurring compound derived from certain mushroom species that can induce entheogenic experiences or an altered state of consciousness. Reed's Self-Transcendence Theory provides a holistic lens to examine existential concerns and mental health in individuals who perceive their illness as potentially life threatening, such as those with cancer. This scoping literature review used Arksey and O’Malley's template to evaluate research examining psilocybin-assisted psychotherapy for patients with cancer. Eight articles met inclusion/exclusion criteria (four quantitative, two mixed methods, and two qualitative). Review findings indicated that the majority of patient experiences were positive, centering on themes of death acceptance, reflection, and broadened spirituality. Although psilocybin-assisted psychotherapy is in early stages of clinical testing, it thus shows promise for carefully screened patients with cancer who have persistent existential suffering. It will be critical for investigators to tailor this emerging intervention to select patients and for clinicians to be engaged in assessment of outcomes and efficacy.

Cardiac Arrhythmia Detection using Dual Tree Wavelet Transform and Convolutional Neural Network

2021 ◽  
Author(s):  
K Reddy Madhavi ◽  
Padmavathi kora ◽  
L Venkateswara Reddy ◽  
J Avanija ◽  
KLS Soujanya ◽  
...  
Keyword(s):  
Neural Network ◽  
Wavelet Transform ◽  
Cardiac Cells ◽  
P Wave ◽  
Computer Assisted ◽  
Ecg Signals ◽  
Coronary Diseases ◽  
Life Saving ◽  
Life Threatening ◽  
Assisted Diagnosis

Abstract The non-stationary ECG signals are used as a key tools in screening coronary diseases. ECG recording is collected from millions of cardiac cells’ and depolarization and re-polarization conducted in a synchronized manner as: The P-wave occurs first, followed by the QRScomplex and the T-wave, which will repeat in each beat. The signal is altered in a cardiac beat period for different heart conditions. This change can be observed in order to diagnose the patient’s heart status. There are life-threatening (critical) and non-life - threatening (noncritical) arrhythmia (abnormal Heart). Critical arrhythmia gives little time for surgery, whereas non-critical needs additional life-saving care. Simple naked eye diagnosis can mislead the detection. At that point, Computer Assisted Diagnosis (CAD) is therefore required. In this paper Dual Tree Wavelet Transform (DTWT) used as a feature extraction technique along with Convolution Neural Network (CNN) to detect abnormal Heart. The findings of this research and associated studies are without any cumbersome artificial environments. The CAD method proposed has high generalizability; it can help doctors efficiently identify diseases and decrease misdiagnosis.

Extracorporeal membrane oxygenation in pheochromocytoma-induced cardiogenic shock

2017 ◽  
Vol 26 (4) ◽  
pp. 314-316 ◽  
Author(s):  
Nadia Bouabdallaoui ◽  
Denis Bouchard ◽  
E. Marc Jolicoeur ◽  
Alexandra Chronopoulos ◽  
Pierre Y Garneau ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Cardiogenic Shock ◽  
Specific Treatment ◽  
Left Ventricular ◽  
Clinical Value ◽  
Membrane Oxygenation ◽  
Cardiopulmonary Support ◽  
Life Saving ◽  
Adrenal Pheochromocytoma ◽  
Life Threatening

Extracorporeal membrane oxygenation has been extensively used for cardiopulmonary support in cardiogenic shock. However, its clinical value in the management of pheochromocytoma crisis remains unclear. We report a rare case of life-threatening cardiogenic shock managed with peripheral venoarterial extracorporeal membrane oxygenation combined with endovascular left ventricular venting, in a 40-year-old female patient, in the setting of unknown adrenal pheochromocytoma. We highlight the life-saving role of extracorporeal membrane oxygenation in undiagnosed endocrine emergencies, allowing cardiac and end-organ recovery, and giving time for accurate diagnosis and specific treatment in such unusual situations.

scholarly journals Adrenal Insufficiency - Aetiology, Diagnosis and Treatment

2015 ◽  
Vol 3 (1) ◽  
pp. 36-47
Author(s):  
Nazma Akter ◽  
Nazmul Kabir Qureshi
Keyword(s):  
Quality Of Life ◽  
Adrenal Insufficiency ◽  
Presenting Symptoms ◽  
Life Saving ◽  
Life Threatening ◽  
Diagnostic Work ◽  
Work Up ◽  
Term Management

Adrenal insufficiency is caused by either primary adrenal failure or by hypothalamic-pituitary impairment of the corticotropic axis. Adrenal insufficiency, first codified in 1855 by Thomas Addison, remains relevant in 2014 because of its lethal nature. Though, it is a rare disease but is life threatening when overlooked. Main presenting symptoms such as fatigue, anorexia and weight loss are nonspecific, thus diagnosis is often delayed. The diagnostic work-up is well established but some pitfalls remain. The diagnosis is adequately established by the 250 ?g ACTH (adrenocorticotropic hormone) stimulation test in most cases. Glucocorticoids provide life saving treatment but long-term quality of life is impaired, perhaps because therapy is not given in a physiologic way. Dehydroepiandrosterone-replacement therapy has been introduced that could help to restore quality of life. It may be useful in pubertal girls, but not in adults. Monitoring of glucocorticoid-replacement is difficult due to lack of objective methods of assessment and is therefore largely based on clinical grounds. Thus, long-term management of patients with adrenal insufficiency remains a challenge, requiring an experienced specialist. DOI: http://dx.doi.org/10.3329/dmcj.v3i1.22238 Delta Med Col J. Jan 2015; 3(1): 36-47

scholarly journals Bowel infarct with mucormycosis of the intestine

2019 ◽  
Vol 6 (7) ◽  
pp. 2609 ◽  
Author(s):  
Bharat Sangal ◽  
Rajeev Sharma ◽  
Molly Joseph ◽  
Debarghya Chatterjee
Keyword(s):  
Septic Shock ◽  
Fungal Infection ◽  
Male Patient ◽  
Adult Male ◽  
Bowel Infarction ◽  
Life Threatening ◽  
Cerebral Infection ◽  
Adult Male Patient

Gastrointestinal mucormycosis is a relatively uncommon opportunistic fungal infection. The classical presentation is that of a rhino-cerebral infection. It is a life threatening, angio-invasive condition typically affecting immunocompromised individuals. Only a handful cases of intestinal mucormycosis have been reported to date. Here, we discuss our experience regarding an adult male patient who succumbed to bowel infarction and perforation with septic shock due to intestinal mucormycosis.

scholarly journals Mucormycosis (Black fungus): An alarming sign for COVID-19 patients

2021 ◽  
Vol 6 (3) ◽  
pp. 136-139
Author(s):  
Ritesh Kumar Srivastav ◽  
Vishal Kumar Vishwakarma ◽  
Shiv Kumar Srivastav ◽  
Mahesh Prasad ◽  
Tarique Mahmood ◽  
...  
Keyword(s):  
Fungal Infection ◽  
Fungal Spores ◽  
Body Part ◽  
The Body ◽  
Fatality Rate ◽  
Health Issues ◽  
Pulmonary Infections ◽  
Skin Injury ◽  
Underlying Condition ◽  
Disseminated Mucormycosis

Mucormycosis (also known as zygomycosis) is a dangerous but uncommon fungal infection caused by a fungus known as mucormycetes. Mucormycosis can be caused by a variety of fungi. Mucormycetes are fungi that belong to the Mucorales scientific order. Molds can be found all over the place. Mucormycosis is a fungal infection that primarily affects persons who have health issues or who use medications that reduce the body's capacity to resist infections and illness. After inhaling fungal spores from the air, it most usually affects the sinuses or lungs. The majority of people are unaffected by these fungus. Breathing in mucormycete spores, on the other hand, can induce an infection in the lungs or sinuses, which can spread to other regions of the body in patients with compromised immune systems. It can also happen as a result of a cut, a burn, or another sort of skin injury. The fatality rate varied based on the patient's underlying condition, the type of fungus, and the affected body part (for example, the mortality rate was 46 percent among people with sinus infections, 76 percent for pulmonary infections, and 96 percent for disseminated mucormycosis). Antifungal medicines such as amphotericin-B, isavuconazole, posaconazole, and various combinations are used to inhibit the growth. Mucormycosis was studied for its spread, symptoms, treatment, prevention, and consequences.

History and experience of a volunteer ambulance first responder scheme in London

2021 ◽  
Vol 13 (8) ◽  
pp. 344-348
Author(s):  
Saman Al-Sahab ◽  
Aditi Nijhawan ◽  
Tim Kirkby ◽  
Shadman Aziz
Keyword(s):  
Cardiac Arrest ◽  
Blue Light ◽  
Response Times ◽  
Ambulance Service ◽  
First Responder ◽  
Emergency Responders ◽  
Life Saving ◽  
Wide Range ◽  
Life Threatening ◽  
Set Up

Emergency responders (ERs) are volunteers who attend category 1 (immediately life-threatening) and category 2 (emergency) 999 calls on behalf of the London Ambulance Service NHS Trust (LAS). ERs aim to arrive first on scene to these incidents to provide essential life-saving interventions prior to the arrival of further ambulance resources. ERs come from a wide range of backgrounds and undergo a thorough selection, training and mentorship process before advancing to working in a two-person ER crew. Compared to most traditional volunteer first responder schemes, the LAS ER scheme, which was set up in 2008, involves an enhanced skillset, dispatch to medical and traumatic emergencies in addition to cardiac arrest, and the use of blue-light vehicles to reduce response times. Over a period of 13 years, the scheme has grown in scope and size, and now operates with more than 120 volunteers based at seven ambulance stations across London.

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