Wstępna diagnostyka chorób krwi

2021 ◽  
Vol 99 (4) ◽  
pp. 177-181
Author(s):  
Wiesław Wiktor Jędrzejczak
Keyword(s):  
Laboratory Tests ◽  
Blood Count ◽  
Urine Analysis ◽  
Complete Blood Count ◽  
Doctor Who ◽  
Blood Disorders ◽  
Blood Disorder ◽  
Erythrocyte Sedimentation ◽  
Initial Symptoms ◽  
Current Article

Final result of treatment of majority of neoplastic and non‑neoplastic blood disorders depends on their early diagnosis and immediate referral to hematologist. This determines that initial hematological diagnosis has to be carried out on the level of family physician or other doctor, who in the process of diagnosis of other disorder will detect abnormalities that may suggest a blood disorder. Current article concerns the use of a triad of laboratory tests: complete blood count, erythrocyte sedimentation rate, and urine analysis. Borderline values are provided that should prompt referral to a hematologist, and it is explained why these particular values were accepted. Common use of such information should shorten time from initial symptoms of blood disorders to the beginning of therapy.

The Management of Febrile Infants by Primary-Care Pediatricians in Utah: Comparison With Published Practice Guidelines

PEDIATRICS ◽  
1995 ◽  
Vol 95 (5) ◽  
pp. 623-627 ◽  
Author(s):  
Paul C. Young
Keyword(s):  
Primary Care ◽  
Practice Guidelines ◽  
Laboratory Tests ◽  
Blood Count ◽  
Response Rate ◽  
Expert Panel ◽  
Complete Blood Count ◽  
Age Groups ◽  
Design Case ◽  
Primary Care Pediatricians

Objective. To determine primary-care pediatricians' management of febrile infants and compare them with published practice guidelines. Design. Case scenarios were sent to 194 primary-care pediatricians in Utah, describing three febrile infants, ages 21 days, 60 days, and 20 months, corresponding to the three age groups: 0 to 28 days; 29 to 90 days, and 91 days to 36 months for which the guidelines suggest different strategies. Results. Ninety-four pediatricians responded (response rate, 48%). Compliance with the guidelines was 39% for the 21 day old, 9.6% for the 60 day old, and 75% for the 20 month old. No respondent followed the guidelines for all three infants. Performance of tests to determine if an infant was low risk varied from 3%, for a stool white cell examination in a febrile 2 month old with diarrhea, to 75% for a complete blood count in a 20 month old with a temperature of 40°C. Compliance did not differ between private and academic practitioners. Those in practice less than 5 years (n = 22) were more likely than those with more experience to follow the guidelines for the 21 day old but not the other two infants. Conclusion. Primary-care pediatricians in Utah manage febrile infants with fewer laboratory tests and less hospitalization than recent practice guidelines developed by an expert panel of academic specialists suggest.

scholarly journals NILAI RUJUKAN HEMATOLOGI PADA ORANG DEWASA SEHAT BERDASARKAN SYSMEX XT-1800i

2018 ◽  
Vol 12 (3) ◽  
pp. 137
Author(s):  
T Esa ◽  
S Aprianti ◽  
M Arif ◽  
Hardjoeno .
Keyword(s):  
Reference Values ◽  
Laboratory Tests ◽  
Blood Count ◽  
Healthy Adult ◽  
Blood Donation ◽  
Complete Blood Count ◽  
Reference Value

The reference values of laboratory tests are affected by factors such as instruments and methods of tests, which are always beingdeveloped. For these reasons, each laboratory is recommended to determine their own reference values. To determine the reference valuesof complete blood count in healthy adult people, and compare them to the reference values which is taken from the references. A crosssectional study was conducted on 200 healthy adult people, aged 18-60 years, selected during blood donation. The eight haematologicalparameters were estimated using Sysmex Xt-1800i at Dr.Wahidin Sudirohusodo Hospital. The data were analyzed statistically by SPSS11.5 programs. The reference values of leukocyte, erythrocyte, haemoglobin, hematocrit, MCV, MCH, MCHC and platelet were: 4400 to10000 /µL; %:4.2–6.2 × 106/µL; &:3.8–5.5 × 106/µL; %:12.5–17.3 g/dL; &:11.8–15.4 g/dL; %:38.1–50.4 %; &:31.1–49.7 %; 80,1to 94,3 fL, 25,9–31,9 pg, 31,4–35,2 g/dL, and %:171.2–405.1 × 103/µL; &:191.8–441.5 × 103/µL, respectively. Significant differenceswere observed in the MCH and platelet values (p< 0,005). The values found in this study were similar to the reference value commonlyused in our laboratory, except for the MCH value which was lower and the platelet value which was higher..

scholarly journals The Correlation between Complete Blood Count Parameters and Appendix Diameter for the Diagnosis of Acute Appendicitis

Healthcare ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 39 ◽  
Author(s):  
Emin Daldal ◽  
Hasan Dagmura
Keyword(s):  
Acute Appendicitis ◽  
Laboratory Tests ◽  
Blood Count ◽  
Complete Blood Count ◽  
Lymphoid Hyperplasia ◽  
White Blood Count ◽  
C Reactive Protein ◽  
Distribution Width ◽  
Lymphocyte Ratio ◽  
Reactive Protein

Acute appendicitis is one of the most common causes of acute abdominal diseases seen between the ages of 10 and 19, mostly seen in males. The lifetime risk of developing acute appendicitis is 8.6% for males and 6.7% for females. We aimed to investigate the efficacy of the complete blood count parameters, C-reactive protein, and Lymphocyte-C-reactive Protein Ratio laboratory tests in the diagnosis of acute appendicitis, as well as their relationship with appendix diameter. We retrospectively examined all patients who underwent appendectomy between 1 January 2012 and 30 June 2019 in the General Surgery Clinic of Gaziosmanpasa University Faculty of Medicine. Laboratory tests, imaging findings, age, and gender were recorded. Lymphoid hyperplasia is considered as normal appendix—in other words, as negative appendicitis. The distribution of Lymphoid hyperplasia and appendicitis rates were statistically different in the groups formed according to appendix diameter (≤6 and >6 mm) (p < 0.001). We found a significant correlation between appendix diameter and WBC (White blood count), Lymphocyte, Neutrophil, RDW(Red blood cell distribution width), NLR(Neutrophil to lymphocyte ratio), and PLT/L (Platelet to lymphocyte ratio), MPV (Mean platelet volume) and RDW were significantly different in patients with an appendix diameter of ≤6 mm (p = 0.007, p = 0.006, respectively). WBC, Neutrophil, PDW, and NLR values were significantly different between appendicitis and hyperplasia groups in patients with an appendix diameter of >6 mm. The sensitivity of the NLR score (cutoff = 2.6057) in the diagnosis of appendicitis was 86.1% and selectivity was 50% in these patients. Complete blood count parameters evaluation with the clinical findings revealed that NLR is an important parameter that may help the diagnosis of acute appendicitis with an appendix diameter of >6 mm. In patients whose pathological results indicated acute appendicitis but who had a diameter of ≤6 mm, we found an elevated MPV and low RDW values.

The Complete Blood Count

2010 ◽  
Vol 29 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Terri Lynne Milcic
Keyword(s):  
Gestational Age ◽  
Laboratory Tests ◽  
Blood Count ◽  
Neonatal Period ◽  
Complete Blood Count ◽  
Clinical Information ◽  
Diagnostic Assessment ◽  
Reference Ranges ◽  
Hematopoietic System ◽  
Common Laboratory

THE COMPLETE BLOOD COUNT (CBC) is one of the more common laboratory tests ordered during the neonatal period. The CBC may be obtained to evaluate for anemia, infection, and thrombocytopenia.1 The test offers a wealth of clinical information about the hematopoietic system, including erythrocyte, leukocyte, and thrombocyte values. Establishing normal neonatal ranges has been difficult because blood has not been drawn on healthy neonates of similar ages.2 Reference ranges that consist of the 5th to 95th percentile compiled from various studies have been used to approximate normal neonatal values.3 A variety of factors such as sample site, timing of the sample, gestational age, and the neonate’s degree of health can affect the CBC.1 Therefore, the astute practitioner must be able to recognize the clues and nuances of the CBC to guide the diagnostic assessment.4

scholarly journals Effects of Pomegranate Juice (Punica Granatum) on Inflammatory Biomarkers and Complete Blood Count in Patients with COVID-19: A Structured Summary of a Study Protocol for a Randomized Clinical Trial

2021 ◽  
Author(s):  
Mojtaba Yousefi ◽  
Mohammadreza Sadriirani ◽  
Azizollah Pourmahmoodi ◽  
Sara Mahmoodi ◽  
Bahar Samimi ◽  
...  
Keyword(s):  
Trial Design ◽  
Blood Count ◽  
Complete Blood Count ◽  
Punica Granatum ◽  
Pomegranate Juice ◽  
Inflammatory Biomarkers ◽  
C Reactive Protein ◽  
Double Blind ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

Abstract ObjectivesThis study is conducted to investigate efficacy of pomegranate juice on inflammatory biomarkers, C-reactive protein (CRP), interleukin 6(IL-6), erythrocyte sedimentation rate (ESR) and complete blood count (CBC) in hospitalized patients with mild to moderate coronavirus disease 2019 (COVID- 19).Trial DesignThis is a randomized, placebo-controlled, double-blind, parallel 2-arm (1:1 ratio) clinical trial.

scholarly journals Role of Loop Ileostomy in the Management of Ulcerative Colitis Patients

2020 ◽  
Vol 15 (2) ◽  
pp. 62-68
Author(s):  
Ahmed N. Hussein
Keyword(s):  
Ulcerative Colitis ◽  
Erythrocyte Sedimentation Rate ◽  
Medical Therapy ◽  
Sedimentation Rate ◽  
Blood Count ◽  
Complete Blood Count ◽  
Loop Ileostomy ◽  
Erythrocyte Sedimentation ◽  
Fulminant Ulcerative Colitis

Background: Ulcerative colitis is a chronic inflammatory condition characterized by relapsing and remitting episodes of inflammation limited to the mucosal layer of the colon.Loop ileostomy might be helpful in the management of the disease. Objective: To evaluate the role of loop ileostomy in the management of ulcerative colitis.  Methods: Between Januarys 2008 and January 2018, patients with fulminant ulcerative colitis resistant to medical therapy had been referred to our surgical unit and were included in our study. Assessment of the patients’ medical status (serum electrolytes, total serum protein, complete blood count, erythrocyte sedimentation rate, general stool exam,and abdominal ultrasound and x-rays) and psychological statuswere done and then preoperative status correction followed by defunctioning loop ileostomy operated upon them and followed postoperatively in hospital for the response fortwo weeks of hospitalization. Results: Twenty patients were included in the study, two patients died postoperatively due to comorbidities and pulmonary embolism. Eighteen of twenty patients had a gradual improvement clinically (mucus diarrhea with/without blood, weight gain, fever, psychological and edema) and in hematological and biochemicalvalues (complete blood count, serum albumin protein, erythrocyte sedimentation rate and electrolytes) within two weeks. Conclusion: Defunctioning loop ileostomy is a simple,less morbidprocedure if compared to other medical treatments which can change the complication features of fulminant ulcerative colitis towards either continue in medical therapy or towards definitive curative surgery and cost effective as it decrease the need for expensive medications.

scholarly journals Hirudin as an anticoagulant for both haematology and chemistry tests

2000 ◽  
Vol 22 (4) ◽  
pp. 109-112 ◽  
Author(s):  
Takeo Kumura ◽  
Masayuki Hino ◽  
Takahisa Yamane ◽  
Noriyuki Tatsumi
Keyword(s):  
Blood Cells ◽  
Laboratory Tests ◽  
Blood Count ◽  
Complete Blood Count ◽  
Clinical Chemistry ◽  
Laboratory Medicine ◽  
Differential Count ◽  
Blood Collection ◽  
Tetraacetic Acid ◽  
Coagulation Pathway

Hirudin, an extract from the leech, has powerful antithrombin activity affecting the blood coagulation pathway. We evaluated the usefulness of hirudin in anticoagulating specimens for routine laboratory tests. Results using blood anticoagulated with hirudin corresponded well with results with blood treated with ethylenediamine tetraacetic acid (EDTA) in the complete blood count (CBC), including white blood cell (WBC) differential count and morphology of blood cells, when CBC was performed within 2 h of blood collection. Clinical chemistry results from hirudin-treated samples were similar to results obtained with serum specimens. Thus, hirudin may be a useful anticoagulant for emergency laboratory medicine.

Comparison of K2 and K3 EDTA Anticoagulant on Complete Blood Count and Erythrocyte Sedimentation Rate

2021 ◽  
Vol 28 (1) ◽  
pp. 75
Author(s):  
Harida Zahraini ◽  
Yulia Nadar Indrasari ◽  
Hartono Kahar
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Blood Count ◽  
Complete Blood Count ◽  
Rank Test ◽  
Cross Sectional ◽  
Erythrocyte Sedimentation ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design

The use of anticoagulants is one of the important pre-analytic factors in hematological tests. Both dipotassium (K2) andtripotassium (K3) Ethylene Diamine Tetraacetic Acid (EDTA) are widely used anticoagulants. International CouncilStandardization of Hematology (ICSH) and several researchers recommend the use of K2 EDTA due to its less hyperosmolareffect on blood cells compared to K3 EDTA. This study aimed to compare the results of Complete Blood Count (CBC) andErythrocyte Sedimentation Rate (ESR) using anticoagulant K2 EDTA and K3 EDTA. This study was an analytic observationalstudy with a cross-sectional design conducted from April to December 2018. The subject of the study were 103 healthyadults selected by consecutive sampling. Blood samples were collected in both anticoagulant tubes with a volume of 3 mLeach. Samples were tested twice, in the first 0 hours and the next 6 hours using Sysmex XN 1000 and Alifax Roller 20 LC.Kolmogorov-Smirnov test, paired T-test and Wilcoxon rank test were used for statistical analysis. The agreement testbetween both anticoagulants was carried out using the Bland Altman plot for parameters with a significant difference. Therewas a significant difference between both anticoagulants for the parameters of hemoglobin, hematocrit MCV, MCHC, RDW,PDW, MPV, PLC-R, and erythrocyte sedimentation rate in both the first and second tests. The agreement test using the BlandAltman plot showed that the difference in these parameters was within the Limit of Agreement (LOA) range of 95%. Thisstudy showed that there were differences in some parameters of complete blood count and erythrocyte sedimentation ratebetween the two anticoagulants (K2 K3 EDTA), but these differences were within the LOA range.

scholarly journals A Novel Technique of Spectral Discrimination of Variants of Sickle Cell Anemia

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Vadivel Masilamani ◽  
Sandanasamy Devanesan ◽  
Fatma AlQathani ◽  
Mashael AlShebly ◽  
Hebatullah Hassan Daban ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
High Performance ◽  
Complete Blood Count ◽  
Sickle Cell Trait ◽  
Strong Support ◽  
Blood Disorders ◽  
Spectral Technique ◽  
Blood Disorder ◽  
Time Period

Sickle cell anemia (SCA) is an inherited blood disorder with worldwide incidence of 15%; out of this, it is found in up to 20% in countries like Kingdom of Saudi Arabia and Bahrain. The standard conventional method of detection is complete blood count (CBC) followed by hemoglobin electrophoresis or high-performance liquid chromatography (HPLC) or both. In this context, spectral detection of variants of sickle cell anemia (SCA) is an innovative technique, which when made accurate and reliable could be an effective alternative, since the instrumentation is compact (5 kg) and hence portable. This makes mass screening even in remote villages possible. In this paper, we give the essential aspects of fluorescent spectral features of sickle cell trait (SCT), sickle cell disease (SCD), beta (β) thalassemia trait (BTT) + SCD, and beta (β) thalassemia disease (BTD) + SCD. All the above four major variants could be discriminated among themselves and also from the normal control blood sample. All these analyses could be carried out with 5 ml of blood, in a time period of 10 minutes. The results of this paper give strong support for an alternative method, a spectral technique, for molecular-level diagnosis of sickle cell anemia and other closely related blood disorders.

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