scholarly journals A New Insight into the Morphology of the Human Liver: A Cadaveric Study

ISRN Anatomy ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Sunitha Vinnakota ◽  
Neelee Jayasree
Keyword(s):  
Human Liver ◽  
Diagnostic Errors ◽  
Left Lobe ◽  
Morphological Features ◽  
Cadaveric Study ◽  
Medical College ◽  
Normal Surfaces ◽  
Medical Undergraduates ◽  
Macroscopic Examination ◽  
Insight Into

Background. Day to day advances in the fields of radiology like sonography and CT need to revive interest in the cadaveric study of morphological features of liver, as the accessory fissures are a potential source of diagnostic errors. Accessory fissures vary from single to multiple over different parts of the liver. Aim. In the present study the morphological features of human liver specimens were evaluated by macroscopic examination and morphometric analysis. Methods. The study was conducted on 58 specimens obtained from cadavers utilized for routine dissection for medical undergraduates from the year 2004 to 2012 in the Anatomy Department of MIMS Medical College. Results. In the present study the livers as described in the established anatomical literature with normal surfaces, fissures, and borders were considered normal. Out of the 58 specimens, 24 were normal without any accessory fissures or lobes and with normal contours. Two specimens were with hypoplastic left lobes. Lingular process of left lobe was observed in only one specimen. Conclusions. Knowledge of the various accessory fissures of liver prevents misdiagnosis of cystic lesions or any pathological lesions of the liver.

scholarly journals Morphology of human liver - A cadaveric study

2019 ◽  
Vol 12 (2) ◽  
pp. 48-52
Author(s):  
Dhanalaxmi D Neginhal ◽  
◽  
Umesh K Kulkarni ◽  
Keyword(s):  
Human Liver ◽  
Cadaveric Study

scholarly journals ASSIMILATING AND REPRODUCING CONCEPTS AFTER PHARMACOLOGY LECTURE - A QUESTIONNAIRE-BASED STUDY

2020 ◽  
pp. 122-125
Author(s):  
SYAM SREEDHARAN ◽  
DHANYA SASIDHARAN PALAPPALLIL ◽  
LAILA KANDATH VEEDU ◽  
HARI SANKAR KN ◽  
ATHIRA MUTHANATTU DIVAKARAN
Keyword(s):  
Poor Performance ◽  
Second Phase ◽  
Simple Explanation ◽  
Medical College ◽  
The Social ◽  
Medical Undergraduates ◽  
Simple Language ◽  
The Subject ◽  
Spss Software ◽  
Short Answer Questions

Objective: Medical undergraduates learn pharmacology during the second phase of MBBS. Considering the expanding list of drugs and volatility associated with its learning, the objective of this study was to describe the factors that interfere with the assimilation and reproduction of the concepts in pharmacology. Methods: This was a descriptive study done in the Department of Pharmacology of a Government Medical College in Central Kerala for a period of 2 months. Five short answer questions were chosen to elicit responses from the participants in the form of a surprise test. A Google fill out form elicited the perception of the participants about learning during the pharmacology lecture. The data were sorted and entered into Statistical Package for the Social Sciences (SPSS) software version 16 (SPSS Inc, Chicago, USA). Descriptive data were expressed using frequencies and percentages. Results: Of the 148 students, 84 (56.75%) participated in the study. For the surprise test, the mean marks scored were 2.24±0.77 (maximum marks 5). Forty-seven (56%) participants claimed that they were attentive in pharmacology lectures only “sometimes.” The majority of the participants 82 (97.6%) “sometimes” found it difficult to imbibe the concepts in pharmacology. Seventy (83.3%) agreed that definitions are difficult to learn as such. Only 10 (11.9%) disagreed with the statement that a drug’s action cannot be interpreted as its use because sometimes actions can aggravate some diseases. Sixty-one (72.6%) participants had difficulty in understanding the word “rationale.” Five minutes break, continuity of topics, separate question-answer session at the end of class, summarization, a video demonstration of the mechanism of action, providing printed lecture notes, simple explanation, mnemonics to learn, clinical correlation, lectures during morning hours, and team-based quizzes were some suggestions to increase the assimilation of the subject. Conclusion: Participants had a mean score which was <50% of the total score. While the scores for definitions varied the question on uses of drugs fetched similar marks; however, the students had poor performance on the question related to rationale. Ignorance about the meaning of the word “rationale” shows the importance of regular feedback and the use of simple language in understanding the problems faced by the participants in learning the concepts in pharmacology.

scholarly journals Changing trends in uterine rupture audit, from the Institute of obstetrics and gynecology, modern government maternity hospital, Osmania medical college

2020 ◽  
Vol 9 (9) ◽  
pp. 3631
Author(s):  
Pratibha Devabhaktuni ◽  
Padmaja Allani ◽  
Maheen F.
Keyword(s):  
Caesarean Section ◽  
Uterine Rupture ◽  
Maternity Hospital ◽  
Fetal Outcome ◽  
Bladder Rupture ◽  
Obstetrics And Gynecology ◽  
Medical College ◽  
Lower Segment Caesarean Section ◽  
Trial Of Labor ◽  
Insight Into

Background: Between January 2001 to September 2003, 46,171 deliveries were recorded, the number of caesarean deliveries during this period of two years and nine months were 16,182 (35.04%).  Methods: An Audit from the Institute of obstetrics and gynecology, of uterine ruptures.Results: Total 81 cases of uterine rupture were managed at the Institute. Total number of scar ruptures managed were, 48/81 uterine ruptures. Five women had previous classical upper segment caesarean, and in previous lower segment caesarean section (LSCS), there were 43 cases of rupture uterus. In two cases following forceps delivery, traumatic uterine ruptures were recorded. Spontaneous ruptures were 31 during the study period. Bladder rupture occurred in 13 cases, 16.04% of uterine ruptures.  The fetal outcome in uterine ruptures 81 cases, live births were 19-23.45%. The number of vaginal births after caesarean section were 261, 215, 186 in the years 2001, 2002 and 2003 at the Institute of obstetrics and gynecology. The number of scar ruptures were 7/261, 9/215, 2/186 in the respective years. Hysterectomy was done in 43/81=53.08%. Rent repair of the uterine rupture was done in 38/81.Conclusions: An Audit from the Institute of obstetrics and gynecology, of uterine ruptures has provided the following data that gives an insight into the practice of obstetrics during the decade 2000 to 2010 in the teaching Institute.  Caesarean deliveries accounted for 35.04% of the total deliveries.  Repeat caesarean sections were 7105, 43.9%. The number of vaginal births after caesarean section (VBAC) were 662. Scar ruptures in VBAC were 18 /662-2.71%. The maternal mortality in MGMH study was 3/81 uterine ruptures-3.7%. Scar ruptures constituted, 48/81-59.25% of uterine ruptures. Trial of labor after caesarean (TOLAC) and VBAC are practiced in the teaching Institute.

scholarly journals Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation

2009 ◽  
Vol 284 (13) ◽  
pp. 8349-8358 ◽  
Author(s):  
Barbara Cellini ◽  
Riccardo Montioli ◽  
Alessandro Paiardini ◽  
Antonio Lorenzetto ◽  
Carla Borri Voltattorni
Keyword(s):  
Human Liver ◽  
Minor Allele ◽  
Alanine:Glyoxylate Aminotransferase ◽  
Insight Into

New insight into the binding modes of TNP-AMP to human liver fructose-1,6-bisphosphatase

2016 ◽  
Vol 165 ◽  
pp. 155-160 ◽  
Author(s):  
Xinya Han ◽  
Yunyuan Huang ◽  
Rui Zhang ◽  
San Xiao ◽  
Shuaihuan Zhu ◽  
...  
Keyword(s):  
Human Liver ◽  
Binding Modes ◽  
Fructose 1,6 Bisphosphatase ◽  
Insight Into

scholarly journals Renitence vacuoles facilitate protection against phagolysosomal damage in activated macrophages

2018 ◽  
Vol 29 (5) ◽  
pp. 657-668 ◽  
Author(s):  
Amanda O. Wong ◽  
Matangi Marthi ◽  
Zachary I. Mendel ◽  
Brian Gregorka ◽  
Michele S. Swanson ◽  
...  
Keyword(s):  
Membrane Damage ◽  
Morphological Features ◽  
Activated Macrophages ◽  
Membrane Ruffling ◽  
Silica Bead ◽  
Mechanistic Insight ◽  
Silica Beads ◽  
Lps Activation ◽  
Kinetics Of ◽  
Insight Into

As professional phagocytes, macrophages are susceptible to endolysosomal membrane damage inflicted by the pathogens and noxious particles they ingest. Whether macrophages have mechanisms for limiting such damage is not well understood. Previously, we reported a phenomenon, termed “inducible renitence,” in which lipopolysaccharide (LPS) activation of macrophages protected their endolysosomes against damage initiated by the phagocytosis of silica beads. To gain mechanistic insight into the process, we analyzed the kinetics of renitence and morphological features of LPS-activated versus resting macrophages following silica bead–mediated injury. We discovered novel vacuolar structures that form in LPS-activated but not resting macrophages following silica bead phagocytosis. Because of their correlation with renitence and damage-resistant nature, we termed these structures “renitence vacuoles” (RVs). RVs formed coincident with silica bead uptake in a process associated with membrane ruffling and macropinocytosis. However, unlike normal macropinosomes (MPs), which shrink within 20 min of formation, RVs persisted around bead-containing phagosomes. RVs fused with lysosomes, whereas associated phagosomes typically did not. These findings are consistent with a model in which RVs, as persistent MPs, prevent fusion between damaged phagosomes and intact lysosomes and thereby preserve endolysosomal integrity.

scholarly journals VARIATIONS OF FISSURES OF LUNGS. Variaciones en la fisuras de los pulmones

2016 ◽  
Vol 4 (2) ◽  
pp. 50-56
Author(s):  
Anterpreet K Arora ◽  
Poonam Verma ◽  
Jagdev Singh Kullar ◽  
Ravi Kant Sharma ◽  
Rajan Singla ◽  
...  
Keyword(s):  
Imaging Techniques ◽  
Anatomical Variations ◽  
Morphological Features ◽  
Cadaveric Study ◽  
Ct Scans ◽  
X Rays ◽  
Medical Field ◽  
Lung Anatomy ◽  
Anatomical Knowledge ◽  
Oblique Fissure

Antecedentes: La conciencia y el conocimiento de las variaciones anatómicas de las fisuras del pulmón es requerido por los discípulos de especialidades interesados para una interpretación precisa sobre diferentes técnicas de imagen. Este conocimiento es necesario para el reconocimiento de la anatomía lobular y así localizar los segmentos broncopulmonar. Por lo tanto, se realizó un estudio cadavérico que informa la prevalencia de variaciones de número de fisuras del pulmón en población Punjabi. Método: Las cavidades torácicas de 50 cadáveres debidamente embalsamados que contienen los pulmones fueron disecados y se observaron las características morfológicas de las variaciones anatómicas como número, fisuras y los lóbulos. Resultados: Cien fisuras pulmonares se observaron en 55 pulmones. Había variaciones en 41 pulmones derecho y 14 pulmones izquierdos. Cinco pulmones derechos mostraron ausencia de fisura horizontal, un pulmón derecho no tenía fisura, quince pulmones derechos mostraron fisura horizontal incompleta. Once pulmones derechos y seis pulmones izquierdos tuvieron fisuras oblicuas incompletas. En cuatro pulmones izquierdos la fisura oblicua estuvo ausente. Se observaron fisuras supernumerarias en cuatro pulmones izquierdos y nueve pulmones derechos. Las conclusiones: El conocimiento anatómico de las variaciones de fisuras y lóbulos puede ser importante, y también para académicos en el campo médico. Las conclusiones con respecto a las variaciones vistas en fisuras de ambos los pulmones fueron comparables con estudios anteriores. Las variaciones de anatomía pulmonar son importantes para ambos: el diagnóstico por radiólogos que interpretan radiografías y escáneres de tomografía computada y el tratamiento de varias enfermedades pulmones por cirujanos al realizar lobectomías y por clínicos que implican todos los dominios de la medicina. Background: Awareness and knowledge of anatomical variations of fissures of lung is required by the disciples of concerned specialties for accurate interpretation on different imaging techniques. This knowledge is necessary for the appreciation of lobar anatomy and thus locating the bronchopulmonary segments. Therefore a cadaveric study was undertaken to report the prevalence of variations involving number of fissures of lung in Punjabi population. Methods: The thoracic cavities of 50 properly embalmed cadavers containing lungs were dissected and morphological features like number, fissures and lobes were observed for the presence of anatomical variations. Results: A total of 100 variant pulmonary fissures appeared in 55 lungs. There were variations in 41 right lungs and 14 left lungs. Five right lungs showed the absence of horizontal fissure, one right lung was without any fissure, fifteen right lungs showed incomplete horizontal fissure. Eleven right lungs and six left lungs had incomplete oblique fissures. In four left lungs oblique fissure was absent. Supernumerary fissure was seen in four left lungs and nine right lungs. Conclusions: Anatomical knowledge of variations of fissures and lobes may be important, and also to academicians in the medical field. The findings regarding the variations seen in fissures of both the lungs were comparable with previous studies. Variations of lung anatomy are important for both the diagnosis by radiologists interpreting X-rays and CT scans and treatment of various lungs diseases by surgeons performing lobectomies and by clinicians involving all the domains of medicine.

scholarly journals Hepatic Lobectomy-Case Report of Two Patients, Performed at Chittagong Medical College Hospital

1970 ◽  
Vol 26 (3) ◽  
pp. 153-157
Author(s):  
SM Ashraf Ali ◽  
Md Margub Hussain
Keyword(s):  
Case Report ◽  
Life Experience ◽  
Left Lobe ◽  
Medical College Hospital ◽  
General Surgeon ◽  
College Hospital ◽  
Socioeconomic Condition ◽  
Low Socioeconomic ◽  
Medical College ◽  
Tertiary Center

Lobectomy of liver is indicated for different conditions; mainly malignancy and trauma. Though it is highly specialized operation and preferably be performed in specialized tertiary center, sometime a general surgeon may not be in a position to avoid the surgery due to very low socioeconomic condition or to tackle emergency traumatic condition. Two case report of Lobectomy of liver; right lobectomy for hepatocellular carcinoma, and left lobectomy for left lobe big cyst and multiple stones in it were performed at Chittagong Medical College Hospital utilizing the existing facilities. Both patients recovered uneventfully. Case I expired after two month and fourteen day, Case II leading a pain free cheerful normal life. Experience of management of these two cases of resection of liver is recorded at Chittagong Medical College Hospital. DOI: 10.3329/jbcps.v26i3.4201 J Bangladesh Coll Phys Surg 2008; 26: 153-157

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