scholarly journals Occurrence of Antibiotic Residues and Antibiotic-Resistant Bacteria in Nile Tilapia Sold in Some Markets in Accra, Ghana: Public Health Implication

2018 ◽  
Vol 7 (6) ◽  
pp. 129 ◽  
Author(s):  
Eric S. Donkor ◽  
Isaac Anim-Baidoo ◽  
Evans Fei ◽  
Collins Amponsah ◽  
Michael Olu-Taiwo ◽  
...  
Keyword(s):  
Public Health ◽  
Nile Tilapia ◽  
Capital City ◽  
Multi Drug Resistance ◽  
Resistant Bacteria ◽  
Antibiotic Residues ◽  
Antibiotic Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Public Health Implication ◽  
Fish Samples

In Ghana there are concerns that antibiotics may be used inappropriately to boost fish production, though no study has investigated this problem. To provide preliminary insights into public health aspects of the problem, we investigated the occurrence of antibiotic residues and antibiotic-resistant bacteria in Nile tilapia (Oreochromis niloticus), a fish commonly cultivated and consumed in Ghana. Two hundred Nile Tilapia fish were randomly sampled from four major markets in Accra, the capital city of Ghana. One hundred samples were screened for antibiotic residues using a microbial inhibition plate test that detects sixteen different antibiotics commonly used in animal husbandry and aquaculture. The other 100 samples were cultured for bacteria using direct culture methods, and the isolates were tested against seven antibiotics by the Kirby Bauer method. The overall prevalence of antibiotic residues in the fish samples was 7%. Bacteria that were isolated from the fish samples were Shigella sonnei (10%), Enterobacter cloacae (7%), Escherichia coli (6%), Salmonella Typhi (3%) and Klebsiella pneumoniae and Proteus mirabilis (2%). All bacteria isolated were susceptible to gentamicin and ciprofloxacin but resistant to ampicillin. Multi-drug resistance (ie resistance to three or more different classes of antibiotics) occurred in 86.7% of the isolates. Nile Tilapia sold in Accra is a source of multi-drug resistant bacteria. Consumption of the fish can also lead to significant exposure to antibiotic residues.

scholarly journals Presence of Antibiotic Residues and Antibiotic Resistant Bacteria in Cattle Manure Intended for Fertilization of Agricultural Fields: A One Health Perspective

Antibiotics ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 410
Author(s):  
Judith Huygens ◽  
Els Daeseleire ◽  
Jacques Mahillon ◽  
Daan Van Elst ◽  
Johan Decrop ◽  
...  
Keyword(s):  
Beef Cattle ◽  
Farmyard Manure ◽  
Multi Drug Resistance ◽  
Resistant Bacteria ◽  
Antibiotic Residues ◽  
Agricultural Field ◽  
Antibiotic Resistant Bacteria ◽  
Salmonella Spp ◽  
Antibiotic Resistant ◽  
E Coli

Antibiotic resistant bacteria and antibiotic residues can enter the environment when using animal manure as fertilizer. Twenty-five mixed beef cattle farmyard manure samples and 9 mixed fattening calf slurry samples from different farms across Belgium were investigated for the presence of 69 antibiotic residues, antibiotic resistant Escherichia coli and Salmonella spp. Doxycycline, oxytetracycline, ciprofloxacin, enrofloxacin, flumequine and lincomycin were detected in all fattening calf slurry samples with mean concentrations of 2776, 4078, 48, 31, 536 and 36 µg/kg manure, respectively. Sulfadiazine was detected at a mean concentration of 10,895 µg/kg. Further, antibiotic residues were found in only 4 of the 25 beef cattle farmyard manure samples. Oxytetracycline was detected twice below 500 µg/kg. Paromomycin, ciprofloxacin and enrofloxacin were detected in a concentration below 100 µg/kg. Of E. coli isolates, 88% and 23% from fattening calf slurry and beef cattle farmyard manure, respectively, were resistant to at least one of the antibiotics tested. Multi-drug resistance was observed at a maximum of 10 and 7 antibiotics, respectively. The occurrence of antibiotic resistant E. coli and antibiotic residues is shown to be higher in fattening calf slurry than in beef cattle farmyard manure used for agricultural field fertilization.

MODELING ANTIBIOTIC RESISTANCE IN PREGNANT WOMAN AND FETUS

2011 ◽  
Vol 19 (03) ◽  
pp. 505-520
Author(s):  
HAI-FENG HUO ◽  
JUN LI ◽  
YU-NING LI
Keyword(s):  
Public Health ◽  
Pregnant Woman ◽  
Transmission Dynamics ◽  
Resistant Bacteria ◽  
Uniform Persistence ◽  
Antibiotic Residues ◽  
Global Public Health ◽  
Antibiotic Resistant ◽  
Gestational Period ◽  
Potential Impact

Infection caused by antibiotic-resistant pathogens is one of global public health problems. Many factors contribute to the emergence and spread of these pathogens. A model which describes the transmission dynamics of susceptible and resistant bacteria in a pregnant woman and the fetus is presented. Detailed qualitative analysis about positivity, boundedness, global stability and uniform persistence of the model is carried out. Numerical simulation and sensitivity analysis show that antibiotic input has potential impact for neonatal drug resistance. Our results show that the resistant bacteria in baby mainly come from antibiotics which are wrongly-used during gestational period, or foods containing antibiotic residues.

Antibiotic-Resistant Bacteria and Antibiotic Residue Contamination in Fresh Raw Foods Sold at Wholesale Markets in Thailand

2021 ◽  
Vol 104 (4) ◽  
pp. 654-662
Keyword(s):  
Bacterial Infection ◽  
Food Samples ◽  
Resistant Bacteria ◽  
Antibiotic Residues ◽  
Wholesale Market ◽  
Antibiotic Resistant Bacteria ◽  
Thai Population ◽  
Antibiotic Resistant ◽  
Raw Foods ◽  
Antibiotic Residue

Objective: To investigate the extent of antibiotic-resistant bacteria and antibiotic residue contamination in fresh raw foods sold at wholesale markets in Thailand, which may be the important drivers of antibiotic-resistant bacteria colonization and antibiotic-resistant bacterial infection in Thai population. Materials and Methods: Fresh raw foods, including food from animal products, seafoods, vegetables, fruits, and honey were purchased from two large wholesale markets in Thailand. Food samples were cultured for antibiotic-resistant bacteria and tested for the presence and amount of antibiotic residue. Results: Among 521 samples for bacterial culture, 86.9% grew at least one kind of bacteria. Enterobacteriaceae were commonly isolated and were commonly resistant to ampicillin (76.7% to 100%). ESBL-producers and ceftriaxone-resistant Enterobacteriaceae were prevalent in swine and duck samples (56.7% to 91.7%). Some isolates were resistant to co-amoxiclav (13.3% to 60.0%) and cefoxitin (5.0% to 30.0%). Colistin-resistant Enterobacteriaceae were observed in pork meat (1.4%) and chicken offal (7.0%). Ertapenem-resistant Enterobacteriaceae were detected in cha-om (26.7%). Among 501 samples for antibiotic residue testing, 37.1% contained at least one antibiotic residue. Enrofloxacin was the most prevalent antibiotic residue, followed by doxycycline and tilmicosin. Although most samples contained less antibiotics than the maximum residue limit (MRL), 7.0% contained an amount of at least one antibiotic above the MRL. Conclusion: Many fresh raw foods sold at wholesale markets in Thailand were contaminated with antibiotic-resistant bacteria, and some contained antibiotic residues. Therefore, Thai people are at risk of being colonized with antibiotic-resistant bacteria and developing antibiotic-resistant bacterial infection due to consuming foods contaminated with antibiotic-resistant bacteria or containing antibiotic residues. Keywords: antibiotic-resistant bacteria, antibiotic residue, fresh raw foods, wholesale market, Thailand

scholarly journals Beyond fecal microbiota transplantation: Developing drugs from the microbiome

2020 ◽  
Author(s):  
Ylaine Gerardin ◽  
Sonia Timberlake ◽  
Jessica R Allegretti ◽  
Mark B Smith ◽  
Zain Kassam
Keyword(s):  
Public Health ◽  
Drug Discovery ◽  
Infectious Diseases ◽  
Health Outcomes ◽  
Patient Care ◽  
Fecal Microbiota Transplantation ◽  
Fecal Microbiota ◽  
Resistant Bacteria ◽  
Antibiotic Resistant Bacteria ◽  
Antibiotic Resistant

Abstract The transfer of live gut microbes may transform patient care across a range of autoimmune, metabolic, hepatic and infectious diseases. One early approach, fecal microbiota transplantation, has shown promise in Clostridiodes difficile infection and the potential for improving clinical and public health outcomes for other antibiotic-resistant bacteria. These clinical successes have motivated the development of microbiome drugs, which will need to address challenges in safety, uniformity, and delivery while seeking to preserve the benefits of using whole microbiome communities as novel therapeutics and an innovative platform for drug discovery.

scholarly journals Antibiotic Resistance in Oral/Respiratory Bacteria

1998 ◽  
Vol 9 (4) ◽  
pp. 522-540 ◽  
Author(s):  
M.C. Roberts
Keyword(s):  
Antibiotic Resistance ◽  
Mercury Resistance ◽  
Resistant Bacteria ◽  
Antibiotic Residues ◽  
Mechanisms Of Resistance ◽  
Antibiotic Resistant Bacteria ◽  
Antibiotic Resistant ◽  
The Past ◽  
Resistant Gene ◽  
Rapid Transport

In the last 20 years, changes in world technology have occurred which have allowed for the rapid transport of people, food, and goods. Unfortunately, antibiotic residues and antibiotic-resistant bacteria have been transported as well. Over the past 20 years, the rise in antibiotic-resistant gene carriage in virtually every species of bacteria, not just oral/respiratory bacteria, has been documented. In this review, the main mechanisms of resistance to the important antibiotics used for treatment of disease caused by oral/respiratory bacteria-including β-lactams, tetracycline, and metronidazole-are discussed in detail. Mechanisms of resistance for macrolides, lincosamides, streptogramins, trimethoprim, sulfonamides, aminoglycosides, and chloramphenicol are also discussed, along with the possible role that mercury resistance may play in the bacterial ecology.

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