scholarly journals Bioactive phenolic acids from Scorzonera radiata Fisch.

2014 ◽  
Vol 12 ◽  
pp. 78-84
Author(s):  
N Tsevegsuren ◽  
P Proksch ◽  
Y Wang ◽  
G Davaakhuu
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Plant ◽  
Crude Extract ◽  
Chromatographic Separation ◽  
Quinic Acid ◽  
Structural Identification ◽  
Benzoic Acids ◽  
Aerial Parts ◽  
Dicaffeoylquinic Acid ◽  
Monoterpene Glycoside

Chromatographic separation of the crude extract obtained from the aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes [4], two new flavonoids, one new quinic acid derivative, as well as twenty known compounds including eight quinic acid derivatives, four flavonoids, two coumarins, five simple benzoic acids, and one monoterpene glycoside. We present here results on isolation and structural identification some active phenolic compounds from the Scorzonera radiata - eight quinic acid derivatives (quinic acid, 4,5-dicaffeoylquinic acid, 4,5-dicaffeoyl-epi-quinic acid, 3,5-dicaffeoylquinic acid, 3,5-dicaffeoyl-epi-quinic acid, chlorogenic acid, 5-p-coumaroylquinic acid (trans), 5-p-coumaroylquinic acid (cis)). Quinic acid derivatives exhibited antioxidative activity.DOI: http://dx.doi.org/10.5564/mjc.v12i0.177 Mongolian Journal of Chemistry Vol.12 2011: 78-84

Phenolic Compounds from the Mongolian Medicinal Plant Scorzonera radiata

2012 ◽  
Vol 67 (3-4) ◽  
pp. 135-143 ◽  
Author(s):  
Yao Wang ◽  
Victor Wray ◽  
Nanzad Tsevegsuren ◽  
Wenhan Lin ◽  
Peter Proksch
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Plant ◽  
Antioxidant Activities ◽  
Quinic Acid ◽  
Natural Compounds ◽  
Mass Spectrometric ◽  
Dpph Assay ◽  
Mass Spectrometric Data ◽  
Spectrometric Data ◽  
Aerial Parts

Chromatographic separation of a crude extract obtained from aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded fifteen natural compounds, including two new flavonoids and one new quinic acid congener, as well as four flavones and eight quinic acid derivatives, all of which are known natural compounds. The structures of the isolated compounds were elucidated on the basis of NMR (1H, 13C, COSY, HMBC, ROESY, and TOCSY) and mass spectrometric data. The antioxidant activities of the quinic acid derivatives were evaluated by the DPPH assay

scholarly journals Phenolic Compounds from An Algerian Endemic Species of Hypochaeris laevigata var. hipponensis and Investigation of Antioxidant Activities

Plants ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 514 ◽  
Author(s):  
Nabila Souilah ◽  
Zain Ullah ◽  
Hamdi Bendif ◽  
Kamel Medjroubi ◽  
Tahar Hazmoune ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Antioxidant Activities ◽  
Quinic Acid ◽  
Total Phenolic ◽  
Antioxidant Action ◽  
Endemic Plant ◽  
Aerial Parts ◽  
Phenolic Constituents ◽  
First Time ◽  
Phenolic And Flavonoid

Hypochaeris laevigata var. hipponensis (Asteraceae) is an endemic plant from Algeria. In the current study, we analyzed for the first time its chemical composition, especially phenolic constituents of dichloromethane (DCM), ethyl acetate (EA), and n-butanol (BuOH) fractionsof the aerial parts of Hypochaeris laevigata var. hipponensis by liquid chromatography-mass spectrometry (LC-MS/MS). The number of phenolic compounds detected in DCM, EA, and BuOH fractions were found to be 9, 20, and 15, respectively. More specifically, 12 phenolic acids were detected. Among them, quinic acid, chlorogenic acid, and caffeic acid were the most abundant ones. Meanwhile, only seven flavonoids were detected. Among them, rutin, apigetrin, and isoquercitrin were the major ones. We also determined the total phenolic and flavonoid contents, and fraction EA showed the highest values, followed by BuOH, and DCM fractions. Furthermore, the antioxidant action was dictated by five methods and the tested plant fractions demonstrated a noteworthy antioxidant action.

scholarly journals Identification of the antimicrobial substances produced by Solanum palinacanthum (Solanaceae)

2008 ◽  
Vol 80 (3) ◽  
pp. 427-432 ◽  
Author(s):  
Aline C. Pereira ◽  
Denilson F. Oliveira ◽  
Geraldo H. Silva ◽  
Henrique C.P. Figueiredo ◽  
Albero J. Cavalheiro ◽  
...  
Keyword(s):  
High Performance ◽  
Antimicrobial Agents ◽  
Quinic Acid ◽  
Aspergillus Ochraceus ◽  
Minimal Inhibitory Concentrations ◽  
Antimicrobial Substances ◽  
Aerial Parts ◽  
Dicaffeoylquinic Acid ◽  
The One ◽  
Antibacterial And Antifungal

To find out natural antimicrobial agents as alternative in therapeutics and to preserve food, the methanol extract of Solanum palinacanthum aerial parts was submitted to purification steps guided by antibacterial and antifungal assays. As a consequence, the flavonoid rutin and 3,5-dicaffeoylquinic acid were isolated by column chromatographyand high performance liquid chromatography, and identified by mass and nuclear magnetic resonance spectrometry. Minimal inhibitory concentrations (MIC) of the quinic acid derivative against Aeromonas hydrophila, Bacillus subtilis, Staphylococcus aureus and the fungus Aspergillus ochraceus were 250, 1000, 1000 and > 568µg/mL, respectively. Against the same microorganisms, MIC for rutin were 1000, > 1000, > 1000 and 35µg/mL, respectively. Rutinwas very promising for A. ochraceus control, since its MIC against such fungus was close to the one observed for benzalkonium chloride, which is used as a fungicide in Brazil.

scholarly journals Identification and Antibacterial Evaluation of Selected Jordanian Medicinal Plants

2018 ◽  
Vol 34 (5) ◽  
pp. 2456-2463
Author(s):  
Wael A. Al-Zereini ◽  
Fuad Al-Rimawi ◽  
Saleh Abu-Lafi ◽  
Fadi Alakhras ◽  
Ghassab M. Al-Mazaideh ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Phenolic Compounds ◽  
Medicinal Plants ◽  
Ethyl Acetate ◽  
Plant Extracts ◽  
Crude Extract ◽  
Hplc Analysis ◽  
Room Temperature ◽  
Aerial Parts ◽  
Antibacterial Evaluation

Dried aerial parts of three medicinal plants grown wild in Jordan, namely Ononis natrix L., Salvia spinosa L. and Salvia verbenace L., were extracted upon soaking with ethyl acetate by continuous shaking at room temperature for three days. The extracts were analyzed for their phenolic and flavonoids content by HPLC-PDA. The HPLC analysis of the plant extracts revealed the presence of flavonoids and phenolic compounds in the three plant extracts. The antibacterial activity of the crude extract was evaluated. The PDA wavelengths range was from 227-347 nm. Bioactivities were attributed mainly to the immense content of phenol-based compounds in plants.

scholarly journals Constituents of Cuscuto Reflexa are anti-HIV Agents

1997 ◽  
Vol 8 (1) ◽  
pp. 70-74 ◽  
Author(s):  
N Mahmood ◽  
S Piacente ◽  
A Burke ◽  
Al Khan ◽  
C Pizza
Keyword(s):  
Crude Extract ◽  
Quinic Acid ◽  
Cuscuta Reflexa ◽  
Gp 120 ◽  
Dicaffeoylquinic Acid ◽  
Pure Compounds ◽  
Specific Proteins ◽  
Anti Hiv Agents ◽  
Anti Hiv

Crude water extracts of Cuscuta reflexa exhibited anti-HIV activity. Fractionation of the crude extract led to the isolation of nine pure compounds with closely related structures, showing interesting structure activity relationships. 3,5,7,4′-Tetrahydroxyflavanone (aromadendrin) inhibited infection by binding to V3 loop of gp 120 and inhibiting its interaction with CD4, whereas 3,5,7,3′,4′-pentahydroxyflavanone (taxifolin), with an extra OH group in the 3′ position in ring B was less specific and exhibited less selectivity in cell cultures. In general, flavanones containing an extra OH group in the 3′ position (taxifolin, taxifolin-7-O-β-D-glucopyranoside and coccinoside B) were less specific and inhibited viral protease, reverse transcriptase, CD4 /gp120 interaction in vitro and bound to non specific proteins. Other compounds isolated from C reflexa were derivatives of quinic acids; 3,4-O-dicaffeoylquinic acid was more active than 3-O-caffeoyl quinic acid. The anti-HIV activity of crude extract may be the result of combinatory effects with compounds of different modes of action.

Phenolic compounds from an Algerian medicinal plant (Pallenis spinosa): simulated gastrointestinal digestion, characterization, biological and enzymatic activities

2021 ◽  
Author(s):  
Hanane Amrani-Allalou ◽  
Lila Boulekbache ◽  
Luana Izzo ◽  
Lynda Arkoub-Djermoune ◽  
Mohamed Lamine Freidja ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Plant ◽  
Folk Medicine ◽  
Enzymatic Activities ◽  
Gastrointestinal Digestion ◽  
Oral Infections ◽  
Simulated Gastrointestinal Digestion

Pallenis spinosa is a medicinal plant which is used in folk medicine as curative or preventive remedies for various diseases such diabetes, respiratory and oral infections. Individual phenolic compounds from...

scholarly journals Modulation of Oxidative Stress and Hemostasis by Flavonoids from Lentil Aerial Parts

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 497
Author(s):  
Jerzy Żuchowski ◽  
Agata Rolnik ◽  
Weronika Adach ◽  
Anna Stochmal ◽  
Beata Olas
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Human Plasma ◽  
Crude Extract ◽  
Lens Culinaris ◽  
Bioactive Substances ◽  
Phenolic Fraction ◽  
Aerial Parts ◽  
Scientific Attention

While specific metabolites of lentil (Lens culinaris L.) seeds and their biological activity have been well described, other organs of this plant have attracted little scientific attention. In recent years, green parts of lentils have been shown to contain diverse acylated flavonoids. This work presents the results of the research on the effect of the crude extract, the phenolic fraction, and seven flavonoids obtained from aerial parts of lentils on oxidative damage induced by H2O2/Fe to lipid and protein constituents of human plasma. Another goal was to determine their effect on hemostasis parameters of human plasma in vitro. Most of the purified lentil flavonoids had antioxidant and anticoagulant properties. The crude extract and the phenolic fraction of lentil aerial parts showed antioxidant activity, only at the highest tested concentration (50 μg/mL). Our results indicate that aerial parts of lentils may be recommended as a source of bioactive substances.

UHPLC-PDA-ESI-MS profile of phenolic compounds in the aerial parts of Cuphea ingrata Cham. & Schltdl.

2021 ◽  
pp. 1-5
Author(s):  
Danuta Sobolewska ◽  
Aleksandra Owczarek ◽  
Monika Olszewska ◽  
Niraldo Paulino ◽  
Irma Podolak ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Esi Ms ◽  
Aerial Parts
Sign in / Sign up

Export Citation Format

Share Document