THE EFFECT OF VIBRO-MASSAGE ON THE LEVEL OF SELECTED MARKER OF MUSCLE DAMAGEAND CONNECTIVE TISSUES AFTER LONG-TERM PHYSICAL EXERCISE IN MALES

2018 ◽  
Vol 28 (82) ◽  
pp. 21-27
Author(s):  
Anna Tyka ◽  
Tomasz Pałka ◽  
Anna Piotrowska ◽  
Danuta Żiżka ◽  
Wanda Pilch ◽  
...  

Study aim. The aim of the study was to examine the influence of using of vibro-massage on specific parameters of frequency, amplitude and pulsation sequence after prolonged physical exercise on post-workout restitution among men, based on the assessment of biochemical concentrations of indicators assessing the degree of damage to muscle cells. Material and methods. A group of 20 men aged 22±2.5 years was selected for the study, with average values of: body height (BH) - 179±1.00 cm, body mass (BM) - 74.3±1.70 kg, percentage of fat content (PF) - 10.8±0.60%, and with a fairly high level of VO2max 52.6±8.0 ml.kg-1.min-1. Results. In two groups - with the use of vibration procedures (VG) and placebo (PG), statistically significant differences were found for lactate concentration (LA) in blood samples (serum) collected after 15, 30 and 60 minutes, as well as MMP-2, Mb and IL-6 1h later and 24 hours following the exercise. Conclusions. It has been shown that a single, strong physical stimulus causes large disturbances of homeostasis in the body, while the use of vibro-massage with the indicated parameters, during rest, results in an increase in the rate of the body’s restitution during the post-exercise phase.

2021 ◽  
Vol 1 (1) ◽  
pp. 8-10
Author(s):  
Michael Chinedu Olisah ◽  
◽  
Dim Catherine Nicholate ◽  

Background: Prolonged exercise leads to progressive water and electrolyte loss from the body as sweat is secreted to promote heat loss. The rate of sweating depends on many factors and is increased in proportion to the work rate and the environmental temperature and humidity. Prolong exercise could lead to an alteration in electrolyte concentrations and this could lead to deleterious effects in the body. Aim: To determine the effect of Physical Exercise on Serum Electrolytes Urea and Creatinine in undergraduate footballers in Anambra State. Method: Six football teams comprising of 11 players each were grouped into 3 sets. Each set containing 22 players was allowed to play football for at least 2hours with a 15 minutes break interval. They were allowed to take only 250mls water during this exercising period. Blood samples were collected from all the subjects prior to the exercise from anticubital veins with the subjects in sitting position. Post-Exercise blood Samples were collected within 5 minutes after and 2hrs after the exercise. The blood samples were also analyzed for serum electrolytes, urea and creatinine. Blood sample for calcium was collected after removing the tourniquet for 2 minutes. The serum concentrations of sodium, potassium, bicarbonate, chloride and calcium were estimated using ion-selective electrodes while urea and creatinine were estimated using standard colorimetric methods. Results: There was no significant difference in mean concentrations of serum electrolytes (Na+, K+, Cl- and HCO3-) profile levels in pre-exercising subjects when compared with the post-exercising period. (P> 0.05). However, the mean levels of Ca2+ increased significantly in post-exercise period when compared with the pre-exercising condition (P < 0.05). The findings of this work suggest that short duration of exercise does not alter significantly the serum electrolytes.


1974 ◽  
Vol 47 (3) ◽  
pp. 249-257 ◽  
Author(s):  
D. F. Marcus ◽  
H. F. Edelhauser ◽  
M. G. Maksud ◽  
R. L. Wiley

1. Normal subjects performed fatiguing static hand-grip contraction at tensions of 20% and 55% of their maximum voluntary contraction (MVC). Intraocular pressure (IOP) was measured by applanation tonometry before, during and after the isometric exercise. Forearm blood samples were taken from the antecubital vein in both the exercised and non-exercised arm before and 2 min post-exercise for measurement of plasma lactate, osmolality, Pv,o2, Pv,co2 and pH. 2. During hand grip the heart rate and blood pressure increased significantly, whereas the IOP remained unchanged from control in both the 20% and 55% MVC experiments. 3. In the recovery period heart rate and blood pressure returned to control values within 3 min and the IOP decreased significantly from control in both the 20% and 55% MVC experiments. 4. When an occlusion cuff was inflated on the exercising arm just before release of the 55% MVC grip, the decreased IOP could be delayed until the cuff was released. 5. Post-exercise blood samples showed elevated lactate concentrations and Pv,o2 and decreased pH in the exercised arm; however, the values remained unchanged in the non-exercised arm. The decreased IOP after exercise may be related to an increased blood lactate concentration.


2021 ◽  
Author(s):  
Wenyuan G. Zhu ◽  
Jamie E. Hibbert ◽  
Kuan-Hung Lin ◽  
Nathaniel D. Steinert ◽  
Jake L. Lemens ◽  
...  

AbstractThis study describes a mouse model of progressive resistance exercise that utilizes a full-body/multi-joint exercise (weight pulling) along with a training protocol that mimics a traditional human paradigm (3 training sessions per week, ∼8-12 repetitions per set, 2 minutes of rest between sets, ∼2 maximal-intensity sets per session, last set taken to failure, and a progressive increase in loading that is based on the individual’s performance). We demonstrate that weight pulling can induce an increase in the mass of numerous muscles throughout the body. The relative increase in muscle mass is similar to what has been observed in human studies, and it is associated with the same type of long-term adaptations that occur in humans (e.g., fiber hypertrophy, myonuclear accretion, and in some instances a fast-to-slow transition in Type II fiber composition). Moreover, we demonstrate that weight pulling can induce the same type of acute responses that are thought to drive these long-term adaptations (e.g., the activation of signaling through mTORC1 and the induction of protein synthesis at 1 hr post-exercise). Collectively, the results of this study indicate that weight pulling can serve as a highly translatable mouse model of progressive resistance exercise.


Biomics ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 75-99
Author(s):  
A.R. Mavzyutov ◽  
R.R. Garafutdinov ◽  
E.Yu. Khalikova ◽  
R.R. Gazizov ◽  
An.Kh. Baymiev ◽  
...  

The emergence of the new SARS-CoV-2 coronavirus has given rise to many enigmas, to which there are no answers yet. However, the degree of threat to humanity, due to the fact that by the beginning of February 2021, more than 100 million people were ill in the world, of which 2 million died, led to the fact that the efforts of many researchers were aimed at combating this disease, including massive sequencing of the complete genomes of SARS-CoV-2, as this is necessary for diagnostics and prediction of the epidemiological situation, including in the long term. Currently, a fairly high level of conservativeness of the SARS-CoV-2 genome is shown, but there is also a significant variability of intra-host viral RNA, confirming the concept of the existence of quasispecies for RNA-containing viruses. As of February 2021, the complete genomes of almost half a million coronavirus isolates have been sequenced worldwide, and a number of nomenclatures have been proposed to streamline their analysis, including the convenient dynamic nomenclature Pango lineage. Variations of SARS-CoV-2 genomes in the form of consensus SNPs (Single Nucleotide Polymorphism) and intra-host iSNVs (intra-host Single Nucleotide Variant) were demonstrated. Taking into account iSNV and minor mutations, about 85% of the 29.9 thousand nucleotides viral genome were changed at least once, but only a very few of them turned into major mutations due to certain features that ensure the predominant distribution of such strains. The example of the S-protein gene, taking into account iSNV, minor and major mutations, shows its significant variability, which is detected when sequencing hundreds of thousands of SARS-CoV-2 genomes. On the basis of the analysis of 400 complete SARS-CoV-2 genomes isolated on the territory of the Russian Federation during 2020, the dynamics of the circulation of individual strains with acquired major mutations, the representation of which is slightly different from the changes in the SARS-CoV-2 genome in the rest world, is estimated. The possibility of long-term persistence of the new coronavirus in the human body is note, while the reservoirs for the latent existence of SARS-CoV-2, in contrast, for example, to the herpes simple virus, remain unknown. There is no consensus on the possibility of reactivation of SARS-CoV-2 or reinfection. The latter is theoretically possible in cases where SARS-CoV-2 strains belonging to other genetic lineages and clades are found in the body of the "re-infected". This, however, does not exclude the possibility of mutating the virus within a single host. Despite significant progress in monitoring the spread of SARS-CoV-2, many questions remain, but as knowledge of the biology of the new coronavirus accumulates, they will also be answered.


1991 ◽  
Vol 37 (11) ◽  
pp. 1978-1980 ◽  
Author(s):  
N Shimojo ◽  
K Fujino ◽  
S Kitahashi ◽  
M Nakao ◽  
K Naka ◽  
...  

Abstract To monitor changes in the concentration of blood lactate during physical exercise, we used an automated lactate analyzer based on an electro-enzymatic method with continuous blood sampling through a catheter. The lactate concentration was measured every 2 min; between measurements, the instrument was calibrated with a lactate standard. Ascorbic acid, bilirubin, hemoglobin, creatinine, uric acid, and glucose did not interfere with the measurements. The lactate concentrations in blood samples from apparently healthy subjects before and after exercise correlated well (r = 0.993) with results by the conventional enzymatic method. We measured the blood lactate concentrations in nine apparently healthy volunteers during exercise on a treadmill with an increasing workload. The point at which lactate concentrations started to increase was detected easily. Thus, the lactate analyzer is suitable for monitoring changes in blood lactate concentrations during exercise.


Cells ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2459
Author(s):  
Wenyuan G. Zhu ◽  
Jamie E. Hibbert ◽  
Kuan Hung Lin ◽  
Nathaniel D. Steinert ◽  
Jake L. Lemens ◽  
...  

This study describes a mouse model of progressive resistance exercise that utilizes a full-body/multi-joint exercise (weight pulling) along with a training protocol that mimics a traditional human paradigm (three training sessions per week, ~8–12 repetitions per set, 2 min of rest between sets, approximately two maximal-intensity sets per session, last set taken to failure, and a progressive increase in loading that is based on the individual’s performance). We demonstrate that weight pulling can induce an increase in the mass of numerous muscles throughout the body. The relative increase in muscle mass is similar to what has been observed in human studies, and is associated with the same type of long-term adaptations that occur in humans (e.g., fiber hypertrophy, myonuclear accretion, and, in some instances, a fast-to-slow transition in Type II fiber composition). Moreover, we demonstrate that weight pulling can induce the same type of acute responses that are thought to drive these long-term adaptations (e.g., the activation of signaling through mTORC1 and the induction of protein synthesis at 1 h post-exercise). Collectively, the results of this study indicate that weight pulling can serve as a highly translatable mouse model of progressive resistance exercise.


2018 ◽  
Vol 18 (1) ◽  
pp. 53-68 ◽  
Author(s):  
Wiesław Krumrych ◽  
Ryszard Gołda ◽  
Marcin Gołyński ◽  
Hanna Markiewicz ◽  
Mateusz Buzała

Abstract The aim of the study was to evaluate the effect of regular physical exercise on cortisol concentration and oxygen-dependent bactericidal activity of neutrophils in peripheral blood in recreational and competitive sport horses (racehorses - Ra, trotters - T, jumping horses - J, driving horses - D). The study was conducted on 55 clinically healthy horses. Blood samples were collected from the external jugular vein three times: before exercise, immediately after exercise, and after 30-min rest. Blood samples were subjected to haematological examination, cortisol concentration was determined by radioimmunoassay (RIA) and neutrophil oxygen metabolism of neutrophils was determined using a chemiluminescence method. The analysis showed that cortisol concentration was significantly higher (P<0.05) post-exercise only in the blood of sport horses. This finding, along with a significant correlation (P<0.00005) with the heart and respiratory rates, suggests that the magnitude of cortisol secretion is associated with the intensity and duration of exercise. The relatively small post-exercise increase in cortisol concentration during different exercises of horses resulted in a transient increase of chemiluminescence activity of neutrophils, mainly in D (P<0.00001) and J horses (P<0.01). In the studied groups analysis of the correlation between cortisol concentration and other parameters showed significant correlation only in the case of the CL total in T (P<0.02) and D horses (P<0.004). It is therefore apparent that in a limited concentration, this hormone may stimulate the activity of these cells, although the effect of other neurohormonal factors cannot be excluded. This result confirms that regular and moderate training loads have a beneficial effect on the immunological status of horses.


2018 ◽  
Vol 32 (1) ◽  
pp. 85-93
Author(s):  
Ana Carolina Ghezzi ◽  
Lucieli Teresa Cambri ◽  
Gustavo Gomes de Araújo ◽  
José Diego Botezelli ◽  
Carla Ribeiro ◽  
...  

It has been shown that engaging in regular physical exercise yields short- and long-term health benefits, primarily by mitigating the risk for cardiovascular disease, but little information is known about physical deconditioning at aging process. The aim of the present study was to analyze the aerobic capacity, through maximal lactate steady state (MLSS), in Wistar rats of different ages (2,4, 6 e 12 months ) and physical conditioning deconditioning responses in middle-aged rats. The results were significant for weight gain in the sedentary (588 ± 71 g) and detraining animals (576 ± 62 g) at 12 months, whereas the conditioned group maintained their original body weights – BW (515 ± 72 g), similar at four (455 ±17 g) and six months of age (471 ± 37 g). MLSS decreased with age (2 months sedentary (8.4 ± 1% Body Weight, 4 months sedentary (6.4 ± 0.6% BW), 6 months sedentary (5.8 ± 1% BW), 12 months sedentary (5.1 ± 0.7% BW), but physical exercise was effective in attenuating the age-related loss of aerobic capacity after 12 months (5.8 ± 1.3% BW). The physical detraining was (5.3 ± 0.4% BW) was similar at 12 months trained. The physical training in long term protected against the increased of the body weight and fat depots caused by aging, but, this effect was found by deconditioning physical. Additionally, the physical training attenuated the aerobic capacity loss due to aging process and this effect was maintained after detraining physical.


Author(s):  
Ario Nakamura ◽  
Hidekazu Asano ◽  
Susumu Kawakami ◽  
Takashi Ito ◽  
Takashi Furukawa ◽  
...  

Overpack, a high-level radioactive waste package for Japan’s geological disposal program, is required for preventing sealed vitrified waste from contact with groundwater for at least 1,000 years. The weld joint between the body and lid must also meet this requirement. Certain welding methods were examined for applicability through full-scale welding tests using various welding depths up to 190 mm and two different lid structures. Results show that generation of welding flaws must be considered unavoidable. Therefore, ultrasonic testing (UT) must be conducted on the assumption that weld flaws will be present. Such UT systems must be designed for natural defects. Several types of UT must be evaluated for detection and size estimation capability at depths ranging from the surface to the bottom of the weld joint. Certain UT methods were examined for their ability to detect natural defects that were created on the surface of and inside a 190-mm thick carbon steel specimen. Probability of detection (POD) of each UT method was calculated by comparing the results of UT and destructive examination. In consideration of the preferred range of scanning depth for each UT method, a concept that combines UT methods was proposed as a practical UT system for the overpack weld joint.


2017 ◽  
Vol 11 (1) ◽  
pp. 460-465 ◽  
Author(s):  
Giovanni Matarese ◽  
Luca Ramaglia ◽  
Luca Fiorillo ◽  
Gabriele Cervino ◽  
Floriana Lauritano ◽  
...  

Introduction: The specialty of periodontology has changed dramatically in recent years. With the long-standing goal of retaining teeth in a functional and esthetical state, the periodontology has developed a high level of expertise in the regeneration of bone and connective tissues that support the teeth. However, periodontists have also joined maxillofacial surgeons as the primary providers of implant surgery. Methods: The tremendous innovations of periodontists induced also by the marketplace resulted in predictable periodontal treatment outcomes for most patients by the implants led to a dramatically different marketplace in which many patients with periodontitis can be treated by the implants rather than the traditional periodontal treatment. Results: The aim of this article is to focus on the innovator’s dilemma for periodontists today is that key elements of our rewarding contributions to dentistry in recent decades are unlikely to be part of a strong and rewarding future for the profession. Conclusions: With the intriguing role of the personalized medicine approach that integrates genomic and clinical information to predict a possible predisposition, we do not suggest a reduced role for periodontists in dental implant surgery but rather a more prominent role in complex cases to achieve surgical implant needs and proper reconstruction and long-term maintenance of the patient’s health.


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