scholarly journals A Comparison of Burden of Disease from Toxic Waste Sites with other Recognized Public Health Threats in India, Indonesia and the Philippines

2014 ◽  
Vol 4 (7) ◽  
pp. 2-13 ◽  
Author(s):  
Jack Caravanos ◽  
Lina Hernandez Gutierrez ◽  
Bret Ericson ◽  
Richard Fuller
Keyword(s):  
Public Health ◽  
Burden Of Disease ◽  
Chemical Exposure ◽  
The Philippines ◽  
Toxic Waste ◽  
World Health ◽  
Health Conditions ◽  
Chromium Vi ◽  
Life Years ◽  
Health Threats

Background. Although toxic waste sites have been well investigated in many developed countries, their prevalence and health impact have not been well documented in low and middle income countries where risks attributable to environmental pollution are generally higher than in developed nations. Methods. We compared the burden of disease from toxic waste sites expressed in disability-adjusted life-years (DALYs) with the same measurement for other threats in India, Indonesia and the Philippines. We used Blacksmith Institute for a Pure Earth's DALY estimates for chemical exposure at 373 toxic waste sites in the 3 countries and World Health Organization (WHO) DALY estimates for different health conditions in the same countries. Results. Chromium VI causes the majority of DALYs among chemicals in India, while lead does so in the Philippines and Indonesia. In India, exposure to chromium VI showed higher DALY estimates than health conditions such as multiple sclerosis, Parkinson's disease and various cancers. In Indonesia, exposure to chromium VI and lead presented higher DALYs than conditions such as upper respiratory infections. In the Philippines, lead had higher DALYs than most of the examined conditions, including malaria and human immunodeficiency virus (HIV)/AIDS. Conclusions. This study highlights that the burden of disease expressed in DALYs from toxic waste sites may be greater than previously recognized and greater than other well addressed public health threats. We call attention to the need for surveillance of toxic waste sites, epidemiological analysis of the associations between exposure to toxic chemicals and outcomes, and remediation of chemical contamination in India, Indonesia and the Philippines.

scholarly journals Burden of disease due to hip, knee, and unspecified osteoarthritis in the Peruvian social health insurance system (EsSalud), 2016

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 238
Author(s):  
Roger V. Araujo-Castillo ◽  
Carlos Culquichicón ◽  
Risof Solis Condor
Keyword(s):  
Health Insurance ◽  
Burden Of Disease ◽  
Hip Osteoarthritis ◽  
Social Health Insurance ◽  
Social Health ◽  
World Health ◽  
Health Insurance System ◽  
Insurance System ◽  
Life Years ◽  
Social Health Insurance System

Introduction: Since its introduction by the World Health Organization (WHO), the concept of burden of disease has been evolving. The current method uses life expectancy projected to 2050 and does not consider age-weighting and time-discounting. Our aim is to estimate the burden of disease due to hip, knee, and unspecified osteoarthritis using this new method in the Peruvian Social Health Insurance System (EsSalud) during 2016. Methods: We followed the original 1994 WHO study and the current 2015 Global Burden of Disease (GBD) methods to estimate disability adjusted life years (DALY) due to osteoarthritis, categorized by sex, age, osteoarthritis type, and geographical area. We used disability weights employed by the Peruvian Ministry of Health, and the last update issued by WHO. Results: Overall, EsSalud reported 17.9 new cases of osteoarthritis per 1000 patients per year. Annual incidence was 23.7/1000 among women, and 72.6/1000 in people above 60 years old. Incidence was 5.6/1000 for knee osteoarthritis and 1.1/1000 for hip. According to the 1994 WHO method, there were 399,884 DALYs or 36.6 DALYs/1000 patients per year due to osteoarthritis. 12.4 and 2.2 DALYs/1000 patients per-year were estimated for knee and hip osteoarthritis, respectively. Using the 2015 GBD method, there were 1,037,865 DALYs or 94.9 DALYs/1000 patients per year. 31.4 and 5.3 DALYs/1000 patients per year were calculated for knee and hip osteoarthritis, respectively. Conclusions: In the Peruvian social health insurance subsystem, hip, knee, and unspecified osteoarthritis produced a high burden of disease, especially among women and patients over 60. The 2015 GBD methodology yields values almost three times higher than the original recommendations.

scholarly journals Global Burden of Alcohol Use Disorders and Alcohol Liver Disease

Biomedicines ◽  
2019 ◽  
Vol 7 (4) ◽  
pp. 99 ◽  
Author(s):  
Jürgen Rehm ◽  
Kevin D. Shield
Keyword(s):  
Liver Disease ◽  
Alcohol Use ◽  
Burden Of Disease ◽  
Alcohol Use Disorders ◽  
World Health ◽  
Years Of Life Lost ◽  
Disease Category ◽  
Mortality And Morbidity ◽  
Economic Wealth ◽  
Life Years

Alcohol use is a major risk factor for burden of mortality and morbidity. Alcoholic liver disease (ALD) and alcohol use disorders (AUDs) are important disease outcomes caused by alcohol use. We will describe the global mortality and burden of disease in disability-adjusted life years for ALD and AUDs, based on data from the comparative risk assessment of the World Health Organization for 2016. AUDs have a limited impact on mortality in this assessment, since alcohol poisonings are almost the only disease category directly attributable to AUDs; most other alcohol-related deaths are indirect, and the cause which directly led to the death, such as liver cirrhosis, is the one recorded on the death certificate. Burden of disease for AUDs is thus mainly due to disability resulting from alcohol use. In contrast to AUDs, ALD is one of the major lethal outcomes of alcohol use, and burden of disease is mainly due to (premature) years of life lost. Many of the negative outcomes attributable to both AUDs and ALD are due to their interactions with other factors, most notably economic wealth. To avoid alcohol-attributable morbidity and mortality, measures should be taken to reduce the AUDs and ALD burden globally, especially among the poor.

scholarly journals Evaluation of the social and economic burden of road traffic noise-attributed myocardial infarction in Bulgarian urban population / Procjena socijalnog i ekonomskog tereta infarkta miokarda povezanog s cestovnom bukom u bugarskog urbanog stanovništva

2015 ◽  
Vol 66 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Angel M. Dzhambov ◽  
Donka D. Dimitrova
Keyword(s):  
Myocardial Infarction ◽  
Economic Burden ◽  
Burden Of Disease ◽  
Urban Population ◽  
Road Traffic ◽  
Traffic Noise ◽  
Significant Proportion ◽  
World Health ◽  
Road Traffic Noise ◽  
Life Years

Abstract Road traffic noise is a widely studied environmental risk factor for ischaemic heart disease and myocardial infarction in particular. Given that myocardial infarction is a leading disability and mortality cause in Bulgaria and that a significant proportion of the urban population is exposed to high noise levels, quantification of the burden of disease attributable to traffic noise is essential for environmental health policy making and noise control engineering. This study aimed at estimating the burden of the myocardial infarction cases attributable to road traffic noise in the Bulgarian urban population. We used the methodology for estimating the burden of disease attributable to environmental noise outlined by the World Health Organization. Risk data were extracted from a recently published meta-analysis providing updated exposureresponse relationship between traffic noise and the risk for myocardial infarction. Based on these data we calculated the fraction of myocardial infarction cases attributable to traffic noise, loss of quality-adjusted life-years (QALYs), and the economic burden, assuming € 12,000 per QALY. About 2.9 % or 101 of all myocardial infarction cases could be attributed to road traffic noise. Fifty-five of these were fatal. Nine hundred and sixty-eight QALYs were lost to these cases. The monetary value of these QALYs was about € 11.6 million. Although the measures used in this study are crude and give only an approximation of the real burden of disease from road traffic noise, they are indicative of the important social and economic aspect of noise pollution in Bulgaria. Hopefully, these results will direct the attention of epidemiologists, environmental hygienists, and health economists to this pivotal environmental issue.

scholarly journals Environmental Burden of Childhood Disease in Europe

2019 ◽  
Vol 16 (6) ◽  
pp. 1084 ◽  
Author(s):  
David Rojas-Rueda ◽  
Martine Vrijheid ◽  
Oliver Robinson ◽  
Aasvang Gunn Marit ◽  
Regina Gražulevičienė ◽  
...  
Keyword(s):  
Risk Factors ◽  
Particulate Matter ◽  
Environmental Risk ◽  
Secondhand Smoke ◽  
Burden Of Disease ◽  
Environmental Risk Factors ◽  
World Health ◽  
Childhood Disease ◽  
Environmental Burden ◽  
Life Years

Background: Environmental factors determine children’s health. Quantifying the health impacts related to environmental hazards for children is essential to prioritize interventions to improve health in Europe. Objective: This study aimed to assess the burden of childhood disease due to environmental risks across the European Union. Methods: We conducted an environmental burden of childhood disease assessment in the 28 countries of the EU (EU28) for seven environmental risk factors (particulate matter less than 10 micrometer of diameter (PM10) and less than 2.5 micrometer of diameter (PM2.5), ozone, secondhand smoke, dampness, lead, and formaldehyde). The primary outcome was disability-adjusted life years (DALYs), assessed from exposure data provided by the World Health Organization, Global Burden of Disease project, scientific literature, and epidemiological risk estimates. Results: The seven studied environmental risk factors for children in the EU28 were responsible for around 211,000 DALYs annually. Particulate matter (PM10 and PM2.5) was the main environmental risk factor, producing 59% of total DALYs (125,000 DALYs), followed by secondhand smoke with 20% of all DALYs (42,500 DALYs), ozone 11% (24,000 DALYs), dampness 6% (13,000 DALYs), lead 3% (6200 DALYs), and formaldehyde 0.2% (423 DALYs). Conclusions: Environmental exposures included in this study were estimated to produce 211,000 DALYs each year in children in the EU28, representing 2.6% of all DALYs in children. Among the included environmental risk factors, air pollution (particulate matter and ozone) was estimated to produce the highest burden of disease in children in Europe, half of which was due to the effects of PM10 on infant mortality. Effective policies to reduce environmental pollutants across Europe are needed.

Forecasting the extent of future public health challenges using the Scottish Burden of Disease study

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
G M A Wyper ◽  
E Fletcher ◽  
I Grant ◽  
G McCartney ◽  
D L Stockton
Keyword(s):  
Public Health ◽  
Population Health ◽  
Burden Of Disease ◽  
Years Of Life Lost ◽  
Ageing Population ◽  
Health Trends ◽  
Life Years ◽  
The Future ◽  
Public Health Challenges ◽  
Disease Study

Abstract Background Over the next 25 years in Scotland there is expected to be negative natural change in population growth in a rapidly ageing population. Recent evidence has highlighted the slowing of life expectancy gains and worsening trends in self-assessed general health. We have adapted the Scottish Burden of Disease study to forecast how demographic and health trends will shape future public health challenges. This is important in order to inform policy, service and workforce planning to meet anticipated needs. Methods For a baseline period of 2014-16 Disability-Adjusted Life Years (DALYs) were estimated for 132 causes of burden using routine data sources and patient-level record linkage techniques. Disability weights and disease models used to calculate Years Lived with Disability (YLD) were largely based on those from the Global Burden of Disease study, with life tables used to facilitate calculations of Years of Life Lost (YLL). The leading 20 causes were identified and trends in the occurrence of morbidity and mortality are currently being estimated up until 2019, and forecast to 2040, using age-period-cohort modelling. Crude and age-standardised rates will be used to monitor changes due to demography and exposure to the wider social determinants of health. Results In 2014-16, the leading causes of burden were ischaemic heart disease, neck and low back pain, depression, lung cancer and cerebrovascular disease. The leading 20 causes represented 68% of all-cause DALYs with ill-health and disability causing almost half of the burden. Conclusions Insights of the future trajectory of population health equip us with strong evidence to influence the need for a strong policy response on prevention. Estimates of the future occurrence of morbidities can be embedded in planning to ensure that services and the care workforce are proportionately designed to meet the increasing needs of a vulnerable ageing population. Key messages The most recent assessment highlighted that non-fatal and fatal health states approximately contribute equally to the overall disease burden in Scotland. Evidencing how future demographic and population health trends interact allows us to ensure that policy responses, care services and the care workforce can be designed based on anticipated needs.

scholarly journals COVID-19 and the rise of social activism in Southeast Asia: a public health concern

2021 ◽  
Author(s):  
Jeff Clyde G Corpuz
Keyword(s):  
Public Health ◽  
Southeast Asia ◽  
Social Activism ◽  
The Philippines ◽  
World Health ◽  
Health Concern ◽  
Human Right ◽  
Health Crisis ◽  
Control And Prevention ◽  
Health Organization

Abstract The current public health crisis has radically altered the social and civic involvement in Southeast Asia. Although the virus has shifted the landscape of engagement, it has not dampened the enthusiasm of the public. In 2020–2021, more people than ever seem to be paying attention and even getting involved in activism. Many dramatic events happened during the coronavirus crisis such as from protests in support of the Black Lives Matter movement, public activism around the environment, economic inequality, authoritarianism and human rights violations. In Indonesia, the Philippines, Malaysia, Thailand and just recently Myanmar. The journal has lately published about the ‘Relationship of George Floyd protests to increases in COVID-19 cases using event study methodology’ and it has rightly expressed that the Centers for Disease Control and Prevention (CDC)-recommended social distancing guidelines must be followed in a protest situation. In response to the situation of social activism in Southeast Asia, one must follow the CDC-recommended and World Health Organization (WHO) guidelines in the Region. Although protesting is an individual human right, one must also be cautious and be aware of the deadly virus since we are still in a pandemic and the COVID-19 virus continues to mutate.

scholarly journals Decomposition of Ethiopian life expectancy by age and cause of mortality; 1990-2010

2016 ◽  
Author(s):  
Gizachew Balew ◽  
Youngtae Cho
Keyword(s):  
Life Expectancy ◽  
Respiratory Infection ◽  
Burden Of Disease ◽  
Neglected Tropical Diseases ◽  
World Health ◽  
Tropical Diseases ◽  
Lower Respiratory Infection ◽  
Diarrheal Diseases ◽  
Life Years ◽  
Tract Infections

Background: Ethiopia, a sub-Saharan country with over 94 million populations growing at a rate of 2.6 percent is showing a fast socio-economic improvement. According to World Health Organization 2014, life expectancy in the country has increased by about 19 years with in the last two decades. It has also reduced child mortality by 2/3rd; two years ahead of millennium development goal deadline. This research will focus in decomposing the improvement in life expectancy in the country from 1990 to 2010. Methods: We used a secondary data on cause and age specific mortality estimate of Ethiopia from institute of health metrics and evaluation. Burden of disease is measured using potential life years lost and potential life years gained using survival 6 program and compared across time. Further improvement in life expectancy is decomposed across age and specific causes using Pollard’s life expectancy decomposition method. Results: Burden of disease measured in weighted years of life lost (YLL) shows that lower respiratory infection at a value of 5.35, neonatal disorders [4.058], diarrheal diseases [3.6], neglected tropical diseases [2.4], meningitis [1.49] and tuberculosis [1.19] are the top causes of burden in 1990 which showed a slight shift in 2010. Lower respiratory tract infections showed the highest reduction in YLL by about 41.27%, followed by diarrheal disease (32.8%) and meningitis (26.46%). Decomposition of life expectancy shows among the total 15.25 years increase in life expectancy from 1990 to 2010, about 5.8 (35.78%) years of increase in life expectancy is achieved through improved longevity in children’s aged 1- 4 year. On the other hand diarrheal diseases reduction contributes about 3.12 [15.96%] followed by lower respiratory infection about 2.54 [12.98%], neglected tropical diseases by 1.45 [7.43%] and tuberculosis by 1.2 [6.25%] years. Conclusions and recommendation: Burden of disease in Ethiopia has declined dramatically which has contributed to the improvement in life expectancy, with the highest reduction already recorded in major communicable diseases. Though it is encouraging that mortality from children has reduced in the country, the slow change in mortality and burden of disease in the general adult population needs future public attention.

scholarly journals An estimation of the global burden of disease due to skin lesions caused by arsenic in drinking water

2005 ◽  
Vol 3 (2) ◽  
pp. 101-107 ◽  
Author(s):  
Lorna Fewtrell ◽  
Ron Fuge ◽  
David Kay
Keyword(s):  
Drinking Water ◽  
Burden Of Disease ◽  
Large Degree ◽  
Skin Lesions ◽  
World Health ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Life Years ◽  
D Region ◽  
Health Organization

The global burden of disease due to skin lesions caused by arsenic in drinking water was estimated by combining country-based exposure data with selected exposure–response relationships derived from the literature. Populations were considered to be exposed to elevated arsenic levels if their drinking water contained arsenic concentrations of 50 μg l−1 or greater. Elevated arsenic concentrations in drinking water result in a significant global burden of disease, even when confining the health outcome to skin lesions. The burden of disease was particularly marked in the World Health Organization (WHO) comparative risk assessment (CRA) ‘Sear D' region, which includes Bangladesh, India and Nepal. Unsurprisingly, Bangladesh was the worst affected country with 143 disability adjusted life years (DALYs) per 1,000 population. Although this initial estimate is subject to a large degree of uncertainty, it does represent an important first step in allowing the comparison of the problem relating to elevated arsenic in drinking water to other environmental health outcomes.

scholarly journals World Health Organization estimates of the global and regional disease burden of four foodborne chemical toxins, 2010: a data synthesis

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 1393 ◽  
Author(s):  
Herman Gibb ◽  
Brecht Devleesschauwer ◽  
P. Michael Bolger ◽  
Felicia Wu ◽  
Janine Ezendam ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Food Supply ◽  
Disease Burden ◽  
Disease Incidence ◽  
Case Fatality ◽  
World Health ◽  
Peanut Allergen ◽  
Major Pathway ◽  
Life Years ◽  
Incidence And Mortality

Background Chemical exposures have been associated with a variety of health effects; however, little is known about the global disease burden from foodborne chemicals. Food can be a major pathway for the general population’s exposure to chemicals, and for some chemicals, it accounts for almost 100% of exposure.  Methods and Findings Groups of foodborne chemicals, both natural and anthropogenic, were evaluated for their ability to contribute to the burden of disease.  The results of the analyses on four chemicals are presented here - cyanide in cassava, peanut allergen, aflatoxin, and dioxin.  Systematic reviews of the literature were conducted to develop age- and sex-specific disease incidence and mortality estimates due to these chemicals.  From these estimates, the numbers of cases, deaths and disability adjusted life years (DALYs) were calculated.  For these four chemicals combined, the total number of illnesses, deaths, and DALYs in 2010 is estimated to be 339,000 (95% uncertainty interval [UI]: 186,000-1,239,000); 20,000 (95% UI: 8,000-52,000); and 1,012,000 (95% UI: 562,000-2,822,000), respectively.  Both cyanide in cassava and aflatoxin are associated with diseases with high case-fatality ratios.  Virtually all human exposure to these four chemicals is through the food supply.  Conclusion Chemicals in the food supply, as evidenced by the results for only four chemicals, can have a significant impact on the global burden of disease. The case-fatality rates for these four chemicals range from low (e.g., peanut allergen) to extremely high (aflatoxin and liver cancer).  The effects associated with these four chemicals are neurologic (cyanide in cassava), cancer (aflatoxin), allergic response (peanut allergen), endocrine (dioxin), and reproductive (dioxin).

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