Glazing Safety and Resilience: New High Performance Options

2021 ◽  
Author(s):  
Stephen R. Miller ◽  
Steven D. Lerner ◽  
Valerie L. Block
Keyword(s):  
High Performance ◽  
Safety Performance ◽  
Optical Performance ◽  
Laminate Composites ◽  
Strengthened Glass ◽  
Over Time

High performance marine glass can be characterized as a product that offers safety from accidental or intentional breakage, as well as resilience over time. The composites that fall into this category often include strengthened glass, tough, durable interlayers that bond the glass, and coatings that provide improved solar optical performance. In addition, the laminate composites deliver acoustical benefits, as well as security benefits beyond the basic safety performance of the material. This paper presents the components that comprise high performance marine glazing, the testing that the products go through, and examples of yachts and vessels that have incorporated high performance features into their glazing specifications.

scholarly journals Rough diamonds in emerging markets: legacy, competitiveness, and sustained high performance

2019 ◽  
Vol 26 (3) ◽  
pp. 363-386
Author(s):  
Seung Ho Park ◽  
Gerardo R. Ungson
Keyword(s):  
Human Capital ◽  
Emerging Markets ◽  
High Performance ◽  
Core Competencies ◽  
Market Potential ◽  
Government Support ◽  
Screening Tests ◽  
Institutional Voids ◽  
Content Type ◽  
Over Time

Purpose The purpose of this paper is to uncover the underlying drivers of sustained high performing companies based on a field study of 127 companies in Brazilian, Russian, Indian and Chinese (BRIC) and Association of Southeast Asian Nations (ASEAN) emerging markets. Understanding these companies provides a complementary way of appraising the growth, development and transformation of emerging markets. The authors synthesize the findings in an overarching framework that covers six strategies for building and sustaining legacy that leads to the succession of intergenerational wealth over time: overcoming institutional voids, inclusive markets, deepening localization, nurturing government support, building core competencies and harnessing human capital. The authors relate these strategies to different levels of development using Prahalad and Hart’s BOP framework. Design/methodology/approach This study examines the underlying drivers of sustained high-performance companies based on field studies from an initial set of 105,260 BRIC companies and close to 500 companies in ASEAN. The methods employed four screening tests to arrive at a selection of the highest-performing firms: 70 firms in the BRIC nations and 58 firms from ASEAN. Following the selection, the authors constructed cases using primary interviews and secondary data, with the assistance of Ernst & Young and with academic colleagues in Manila. These studies were originally conducted in two separate time periods and reported accordingly. This paper synthesizes the findings of these two studies to arrive at an extended integrative framework. Findings From the cases, the authors examine six strategies for building and sustaining legacy that lead to high performance over time: overcoming institutional voids, creating inclusive markets, deepening localization, nurturing government support, building core competencies and harnessing human capital. To address the evolving state of institutional voids in these countries, the authors employ similar methods to hypothesize the placement of these strategies in the context of the world economic pyramid, initially formulated as the “bottom of the pyramid” framework. Originality/value This paper synthesizes and extends the authors’ previous works by proposing the concept of legacy to describe the emergence and succession of local exemplary firms in emerging markets. This study aims to complement extant measures of nation-growth based primarily on GDP. The paper also extends the literature on institutional voids in shifting the focus from the mix of voids to their evolving state. Altogether, the paper provides a complementary narrative on assessing the market potential of emerging markets by adopting several categories of performance.

scholarly journals Markov-Modulated Continuous-Time Markov Chains to Identify Site- and Branch-Specific Evolutionary Variation in BEAST

2020 ◽  
Vol 70 (1) ◽  
pp. 181-189
Author(s):  
Guy Baele ◽  
Mandev S Gill ◽  
Paul Bastide ◽  
Philippe Lemey ◽  
Marc A Suchard
Keyword(s):  
High Performance ◽  
Markov Models ◽  
Marginal Likelihood ◽  
Likelihood Estimation ◽  
Phylogenetic Inference ◽  
Time Variability ◽  
Substitution Process ◽  
Wide Range ◽  
Markov Modulated ◽  
Over Time

Abstract Markov models of character substitution on phylogenies form the foundation of phylogenetic inference frameworks. Early models made the simplifying assumption that the substitution process is homogeneous over time and across sites in the molecular sequence alignment. While standard practice adopts extensions that accommodate heterogeneity of substitution rates across sites, heterogeneity in the process over time in a site-specific manner remains frequently overlooked. This is problematic, as evolutionary processes that act at the molecular level are highly variable, subjecting different sites to different selective constraints over time, impacting their substitution behavior. We propose incorporating time variability through Markov-modulated models (MMMs), which extend covarion-like models and allow the substitution process (including relative character exchange rates as well as the overall substitution rate) at individual sites to vary across lineages. We implement a general MMM framework in BEAST, a popular Bayesian phylogenetic inference software package, allowing researchers to compose a wide range of MMMs through flexible XML specification. Using examples from bacterial, viral, and plastid genome evolution, we show that MMMs impact phylogenetic tree estimation and can substantially improve model fit compared to standard substitution models. Through simulations, we show that marginal likelihood estimation accurately identifies the generative model and does not systematically prefer the more parameter-rich MMMs. To mitigate the increased computational demands associated with MMMs, our implementation exploits recent developments in BEAGLE, a high-performance computational library for phylogenetic inference. [Bayesian inference; BEAGLE; BEAST; covarion, heterotachy; Markov-modulated models; phylogenetics.]

scholarly journals Trajectory classes of job performance

2015 ◽  
Vol 20 (4) ◽  
pp. 424-442 ◽  
Author(s):  
Mariella Miraglia ◽  
Guido Alessandri ◽  
Laura Borgogni
Keyword(s):  
Individual Differences ◽  
Job Performance ◽  
Self Efficacy ◽  
High Performance ◽  
Organizational Transformation ◽  
Growth Mixture Modeling ◽  
Content Type ◽  
Stable Class ◽  
Supervisory Ratings ◽  
Over Time

Purpose – Previous literature has recognized the variability of job performance, calling attention to the inter-individual differences in performance change. Building on Murphy’s (1989) theoretical model of performance, the purpose of this paper is to verify the existence of two distinct classes of performance, reflecting stable and increasing trends, and to investigate which personal conditions prompt the inclusion of individuals in one class rather than the other. Design/methodology/approach – Overall job performance was obtained from supervisory ratings for four consecutive years for 410 professionals of a large Italian company going through significant reorganization. Objective data were merged with employees’ organizational tenure and self-efficacy. Growth Mixture Modeling was used. Findings – Two main groups were identified: the first one started at higher levels of performance and showed a stable trajectory over time (stable class); the second group started at lower levels and reported an increasing trajectory (increasing class). Employees’ with stronger efficacy beliefs and lower tenure were more likely to belong to the stable class. Originality/value – Through a powerful longitudinal database, the nature, the structure and the inter-individual differences in job performance over time are clarified. The study extends Murphy’s (1989) model, showing how transition stages in job performance may occur also as a result of organizational transformation. Moreover, it demonstrates the essential role of self-efficacy in maintaining high performance levels over time.

scholarly journals Nitrogen fertilization in the contents of secondary compounds in cassava cultivars

2018 ◽  
Vol 39 (3) ◽  
pp. 1015 ◽  
Author(s):  
Diego Gazola ◽  
Claudemir Zucareli ◽  
Rudiney Ringenberg ◽  
José Perez da Graça ◽  
Clara Beatriz Hoffmann-Campo
Keyword(s):  
Nitrogen Fertilization ◽  
Acid Content ◽  
High Performance ◽  
Secondary Compounds ◽  
Nitrogen Fertilizers ◽  
Liquid Chromatograph ◽  
Cultural Management ◽  
Potted Plants ◽  
N Rates ◽  
Over Time

The production of chemical substances is a strategy of plants to defend against the attack of pest insects. The synthesis of secondary compounds in plants is influenced by genotype and cultural management, such as the use of nitrogen fertilizers. Thus, the objective of this work is to evaluate the effect of doses of nitrogen fertilizer over time on the production of secondary compounds in two industrial cassava cultivars. The experiment was carried out in a greenhouse (25 ± 5 °C) of Embrapa Soybean in Londrina, Paraná, with the cultivation of potted plants (4l) in a 2 × 4 × 3 factorial scheme, with five replications. Two genotypes of industrial cassava (‘Baianinha’ and ‘Caiuá’) and four different nitrogen doses (0, 30, 60, and 90 kg ha-1) were used, with sampling at 15, 30, and 45 d after fertilization. Nitrogen fertilization was performed 50 d after sprouting. In the apical leaves, the levels of rutin, caffeic, p-coumaric and ferulic acids were evaluated in a high performance liquid chromatograph (HPLC). Exploratory analyses were performed on the data variables to verify the assumptions for analysis of variance (ANOVA), such as the independence and normality of errors, homogeneity of treatment variances and non-additivity of the model (they were submitted to analysis of homogeneity and normality, respectively. After these tests, ANOVA and Tukey’s test (p ? 0.05) were performed. For the quantitative data concerning the N rates, regression study analyzes were performed. The Caiuá cultivar was found to have a higher ferulic acid content. The caffeic acid content decreased over time after the application of N in both cultivars. The rutin content in both cultivars did not increase with an increase in nitrogen dose. At a dose of 90 kg ha-1, both cultivars presented a lower p-coumaric acid content after 30 d.

scholarly journals STABILITY EVALUATION OF CAFFEINE-8-THIOGLICOLIC ACID AMIDES, WITH DETERMINED ANTIHYPOXIC EFFECTS

2017 ◽  
Vol 5 ◽  
pp. 1266-1274
Author(s):  
Javor Mitkov ◽  
Maya Georgieva ◽  
Alexander Zlatkov
Keyword(s):  
High Performance ◽  
Thioglycolic Acid ◽  
Degradation Products ◽  
New Product ◽  
Reversed Phase ◽  
Controlled Synthesis ◽  
Stability Evaluation ◽  
Chromatography Method ◽  
Liquid Chromatography Method ◽  
Over Time

This study evaluates a series of caffeine-8-thioglycolic acid amides that were synthesized in the study, for signs of possible degradation. The chemical stability of the test compounds was examined under different conditions of pH and temperature over time. A modified reversed phase-high-performance liquid chromatography method was applied to determine stability and identify possible degradation products. The study identified a new product from oxidative destruction of the test compound through controlled synthesis.

scholarly journals Changes in the contents of kaempherol, quercetin and L-ascorbic acid in sea buckthorn berries during maturation

2000 ◽  
Vol 9 (1) ◽  
pp. 17-22 ◽  
Author(s):  
N. JEPPSON ◽  
G. XIANGQUN
Keyword(s):  
Ascorbic Acid ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Sea Buckthorn ◽  
Maturation Stages ◽  
The Mean ◽  
Over Time

The contents of kaempherol, quercetin and L-ascorbic acid in sea buckthorn berries were measured at different maturation stages using High Performance Liquid Chromatography (HPLC) methods. The content of ascorbic acid decreased over time with significant differences between sampling dates for the five cultivars studied. The mean decrease was 25% in 19 days, from 1.48 to 1.10 g kg-1. Quercetin decreased whereas kaempherol increased during maturation. Among three studied cultivars, the decrease in quercetin was significant (from 0.028 to 0.014 g kg-1) in 'Otradnaja', where as the increase (from 0.012 to 0.016 g kg-1) in kaempherol was significant in the others two, 'Prozratnaja' and 'Gibrid Pertjik'.;

Research Note Problems in Monitoring the Safety Performance of British Manufacturing at the End of the Twentieth Century

1994 ◽  
Vol 42 (1) ◽  
pp. 104-110 ◽  
Author(s):  
Theo Nichols
Keyword(s):  
Labour Force ◽  
Industrial Relations ◽  
Health And Safety ◽  
Injury Rate ◽  
Safety Performance ◽  
Fatality Rate ◽  
Labour Force Survey ◽  
Short Account ◽  
Related Research ◽  
Over Time

I have frequently expressed the view that the statistics for over three day injuries cannot be relied upon for the sort of temporal research on safety in which I have recently been engaged, for instance concerning the effectiveness of the 1974 Health and Safety at Work Act (Nichols, 1989a; 1990). It has been suggested in the context of some related research (Nichols, 1989b; 1991a) that the over three day injury rate may actually be a useful indicator of safety in some respects and that the fatality rate may not be (Tombs, 1992).1 By contrast, the following short account looks to the future and considers whether, in the 1990s, a point has been reached when any official injury statistics for employees in UK manufacturing can provide satisfactory monitoring of improvements or otherwise in safety over time. First, the fatality rate is briefly discussed, then the rate for major injuries, then the rate for over three day injuries. Two other new sources of injury data are also briefly considered, the 1990 Labour Force Survey (LFS) and the 1990 Work Industrial Relations Survey (WIRS3).

scholarly journals Effects of humeral intraosseous epinephrine in a pediatric hypovolemic cardiac arrest porcine model

2020 ◽  
Vol 5 (1) ◽  
pp. e000372
Author(s):  
Michael James Neill ◽  
James M Burgert ◽  
Dawn Blouin ◽  
Benjamin Tigges ◽  
Kari Rodden ◽  
...  
Keyword(s):  
High Performance ◽  
Porcine Model ◽  
Spontaneous Circulation ◽  
Sample Collection ◽  
Return Of Spontaneous Circulation ◽  
Concentration Maximum ◽  
Group 5 ◽  
Mean Concentration ◽  
Over Time ◽  
Group 1

BackgroundAims of the study were to determine the effects of humerus intraosseous (HIO) versus intravenous (IV) administration of epinephrine in a hypovolemic, pediatric pig model. We compared concentration maximum (Cmax), time to maximum concentration (Tmax), mean concentration (MC) over time and return of spontaneous circulation (ROSC).MethodsPediatric pig were randomly assigned to each group (HIO (n=7); IV (n=7); cardiopulmonary resuscitation (CPR)+defibrillation (defib) (n=7) and CPR-only group (n=5)). The pig were anesthetized; 35% of the blood volume was exsanguinated. pigs were in arrest for 2 min, and then CPR was performed for 2 min. Epinephrine 0.01 mg/kg was administered 4 min postarrest by either route. Samples were collected over 5 min. After sample collection, epinephrine was administered every 4 min or until ROSC. The Cmax and MC were analyzed using high-performance liquid chromatography. Defibrillation began at 3 min postarrest and administered every 2 min or until ROSC or endpoint at 20 min after initiation of CPR.ResultsAnalysis indicated that the Cmax was significantly higher in the IV versus HIO group (p=0.001). Tmax was shorter in the IV group but was not significantly different (p=0.789). The MC was significantly greater in the IV versus HIO groups at 90 and 120 s (p<0.05). The IV versus HIO had a significantly higher MC (p=0.001). χ2 indicated the IV group (5 out of 7) had significantly higher rate of ROSC than the HIO group (1 out of 7) (p=0.031). One subject in the CPR+defib and no subjects in the CPR-only groups achieved ROSC.DiscussionBased on the results of our study, the IV route is more effective than the HIO route.

QUANTITATION OF NEUROTROPHIN mRNA IN SKELETAL MUSCLE: CHANGES DURING THE PROCESS OF PERIPHERAL NERVE REGENERATION

2006 ◽  
Vol 10 (03) ◽  
pp. 131-140 ◽  
Author(s):  
Yasushi Morisawa ◽  
Shinichiro Takayama ◽  
Kazuhiko Okushi ◽  
Toshiyasu Nakamura ◽  
Keiichi Fukuda ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Nerve Injury ◽  
High Performance ◽  
Peripheral Nerve Regeneration ◽  
Hplc Method ◽  
Mrna Levels ◽  
Muscle Changes ◽  
Over Time

Peripheral nerve injury changes the kinetics of neurotrophins. The production of several neurotrophins increases at the site of injury. Although numerous reports have described changes in neurotrophins over time in areas of nerve injury, neurotrophin mRNA is present at very low levels in target tissues, making accurate quantitation difficult. We developed a reverse transcription–polymerase chain reaction/high-performance liquid chromatography (RT-PCR/HPLC) method that enables accurate quantitation of neurotrophin mRNA. We then attempted to quantitate mRNA levels for nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) produced by skeletal muscle innervated by the sciatic nerve following transection and reattachment of the nerve in mice. In addition, wet weights of the muscle were measured and changes in weight over time were determined. The results indicated that neurotrophin production in muscle increases as a result of peripheral nerve denervation due to transection, and decreases with nerve regeneration and reinnervation resulting from reattachment.

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