Effects of Cognitive Stimulation Task on Cognitive State and Activity Participation in Elderly People with Mild Cognitive Impairment (MCI)

Background: Mild cognitive impairment (MCI) is a cognitive state associated with increased risk of dementia. Little research on MCI exists from low-and middle-income countries (LMICs), despite high prevalence of dementia in these settings. Objective: This systematic review aimed to review epidemiological reports to determine the prevalence of MCI and its associated risk factors in LMICs. Methods: Medline, Embase, and PsycINFO were searched from inception until November 2019. Eligible articles reported on MCI in population or community-based studies from LMICs. No restrictions on the definition of MCI used as long as it was clearly defined. Results: 4,621 articles were screened, and 78 retained. In total, n = 23 different LMICs were represented; mostly from China (n = 55 studies). Few studies from countries defined as lower-middle income (n = 14), low income (n = 4), or from population representative samples (n = 4). There was large heterogeneity in how MCI was diagnosed; with Petersen criteria the most commonly applied (n = 26). Prevalence of aMCI (Petersen criteria) ranged from 0.6%to 22.3%. Similar variability existed across studies using the International Working Group Criteria for aMCI (range 4.5%to 18.3%) and all-MCI (range 6.1%to 30.4%). Risk of MCI was associated with demographic (e.g., age), health (e.g., cardio-metabolic disease), and lifestyle (e.g., social isolation, smoking, diet and physical activity) factors. Conclusion: Outside of China, few MCI studies have been conducted in LMIC settings. There is an urgent need for population representative epidemiological studies to determine MCI prevalence in LMICs. MCI diagnostic methodology also needs to be standardized. This will allow for cross-study comparison and future resource planning.

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Mild cognitive impairment in the elderly Relationship between communication and functional capacity

Dementia & Neuropsychologia ◽

10.1590/1980-57642018dn12-020009 ◽

2018 ◽

Vol 12 (2) ◽

pp. 165-172 ◽

Cited By ~ 1

Author(s):

Ana Iza Gomes da Penha Sobral ◽

Cláudia Marina Tavares de Araújo ◽

Marcos Felipe Falcão Sobral

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Activities Of Daily Living ◽

Elderly People ◽

Communication Skills ◽

Social Communication ◽

Daily Living ◽

The Elderly ◽

Intermediate Form ◽

Instrumental Activities

Abstract Mild Cognitive Impairment is characterized as an intermediate form between age-related change and dementia. For the elderly, autonomy and independence are related to the ability to remain active in conducting their social activities and, for this to occur, communication is fundamental in this process. Objective: To assess the association between communication and the abilities of elderly people with mild cognitive impairment to perform instrumental activities of daily living. Methods: A cross-sectional, quantitative, analytical, correlational study was conducted at the Open University of the Third Age (UnATI), a program of the Federal University of Pernambuco. This study included 92 people, comprising 46 elderly with mild cognitive impairment and a caregiver or family member who met the inclusion criteria. The elderly were asked to complete a sociodemographic questionnaire and Lawton-Brody’s Instrumental Activities of Daily Living Scale. The caregivers were asked to complete the Functional Assessment of Communication Skills. The following variables were studied: social communication skills and instrumental activities of daily living. Data were stored in an Excel® 2007 spreadsheet, and the Pearson correlation test was used for the statistical analysis. Results: There were statistically significant correlations in four domains of social communication: referring to family members by name (p=0.0033); requesting information about people or events (p=0.0355); understanding conversations in a noisy environment (p=0.0448); and understanding what they watch on television or listen to on the radio (p=0.0127). Conclusion: Changes in the communication of elderly people with mild cognitive impairment interfere with their ability to perform instrumental activities autonomously and independently.

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Effects of health education in the elderly with mild cognitive impairment

Revista Brasileira de Enfermagem ◽

10.1590/0034-7167-2017-0032 ◽

2018 ◽

Vol 71 (suppl 2) ◽

pp. 801-810 ◽

Cited By ~ 4

Author(s):

Francine Golghetto Casemiro ◽

Diana Monteiro Quirino ◽

Maria Angélica Andreotti Diniz ◽

Rosalina Aparecida Partezani Rodrigues ◽

Sofia Cristina Iost Pavarini ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Health Education ◽

The Elderly ◽

Anxiety Symptoms ◽

Control Group ◽

Controlled Clinical Trial ◽

Cognitive State ◽

Paired Samples ◽

Education Group

ABSTRACT Objective: to analyze the effects of health education on both cognition and depressive/anxiety symptoms in the elderly with Mild Cognitive Impairment (MCI). Method: this is a randomized and controlled clinical trial. Participants (n=22) were recruited from a specialized outpatient clinic, and assigned into two groups: a Health Education Group (HEG) (n=10) and a Control Group (CG) (n=12). The participants were evaluated before and after the intervention, which was composed of classes and dynamics. The intervention consisted of 20 meetings, over a period of five months. The assessment was performed by means of the Addenbrooke’s Cognitive Examination – Revised (ACER), the Mini-Mental State Examination to access participant’s cognitive state, and the Beck’s Scale to access depressive/anxiety symptoms. A Memory Complaints Scale (EQM) was also used. The analysis was carried out using the Student’s t test for paired samples. Results: the HEG group demonstrated an improvement in attention/orientation (p= 0,026), memory (p=0.001), language (p= 0.033), and ACE-R (p= 0.003). On the other hand, the CG did not present improvement. Conclusion: the results highlight the importance of non-pharmacological interventions in older adults with MCI to reduce cognitive deficits.

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Validity of a novel computerized screening test system for mild cognitive impairment

International Psychogeriatrics ◽

10.1017/s1041610218000923 ◽

2018 ◽

Vol 30 (10) ◽

pp. 1455-1463 ◽

Cited By ~ 5

Author(s):

Jin-Hyuck Park ◽

Minye Jung ◽

Jongbae Kim ◽

Hae Yean Park ◽

Jung-Ran Kim ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Elderly People ◽

Predictive Value ◽

Screening Test ◽

Concurrent Validity ◽

Test System ◽

Screening Tests ◽

Validity And Reliability ◽

Healthy Elderly

ABSTRACTBackground:The mobile screening test system for screening mild cognitive impairment (mSTS-MCI) was developed for clinical use. However, the clinical usefulness of mSTS-MCI to detect elderly with MCI from those who are cognitively healthy has yet to be validated. Moreover, the comparability between this system and traditional screening tests for MCI has not been evaluated.Objective:The purpose of this study was to examine the validity and reliability of the mSTS-MCI and confirm the cut-off scores to detect MCI.Method:The data were collected from 107 healthy elderly people and 74 elderly people with MCI. Concurrent validity was examined using the Korean version of Montreal Cognitive Assessment (MoCA-K) as a gold standard test, and test–retest reliability was investigated using 30 of the study participants at four-week intervals. The sensitivity, specificity, positive predictive value, and negative predictive value (NPV) were confirmed through Receiver Operating Characteristic (ROC) analysis, and the cut-off scores for elderly people with MCI were identified.Results:Concurrent validity showed statistically significant correlations between the mSTS-MCI and MoCA-K and test–rests reliability indicated high correlation. As a result of screening predictability, the mSTS-MCI had a higher NPV than the MoCA-K.Conclusions:The mSTS-MCI was identified as a system with a high degree of validity and reliability. In addition, the mSTS-MCI showed high screening predictability, indicating it can be used in the clinical field as a screening test system for mild cognitive impairment.

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LINGUISTIC MEASURES OF SPOKEN UTTERANCES FOR DETECTING MILD COGNITIVE IMPAIRMENT

Innovation in Aging ◽

10.1093/geroni/igz038.826 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

pp. S224-S225

Author(s):

Meysam Asgari ◽

Jeffrey Kaye ◽

Hiroko Dodge

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Cognitive Stimulation ◽

Support Vector ◽

Svm Classifier ◽

Healthy Controls ◽

Document Frequency ◽

Trained Interviewer ◽

Validation Procedure ◽

Characteristic Area

Abstract Studies have shown that speech characteristics can aid in early-identification of those with mild cognitive impairment (MCI). We performed a linguistic analysis on spoken utterances of 41 participants (15 MCI, 26 healthy controls) from conversations with a trained interviewer using the Term Frequency-Inverse Document Frequency (TF-IDF) method. Data came from a randomized controlled behavioral clinical trial (ClinicalTrials.gov: NCT01571427) to examine effects of conversation-based cognitive stimulation on cognitive functions among older adults with normal cognition or MCI, which served as a pilot study for I-CONECT. From the collected spoken utterances we first constructed a fixed-dimensional feature vector using TF-IDF. Next, to distinguish between MCI and healthy controls, we trained a support vector machine (SVM) classifier on per-subject feature vectors according to 5-fold cross-validation procedure. Our results verify the effectiveness of TF-IDF features in this classification task with Receiver Operating Characteristic Area Under Curve of 81%, well above chance at 65%.

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Trait Impulsivity Is Independent of Mild Cognitive Impairment in a Parkinson’s Disease Cohort

Parkinson s Disease ◽

10.1155/2019/2672075 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6

Author(s):

Ashani Jeyadevan ◽

Megan C. Bakeberg ◽

Michelle Byrnes ◽

Jade Kenna ◽

Soumya Ghosh ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Cognitive Complexity ◽

Self Control ◽

Cognitive State ◽

Normal Cognitive Function ◽

Trait Impulsivity ◽

Motor Impulsivity

Introduction. Patients with Parkinson’s disease (PD) commonly experience cognitive deficits and some also develop impulse control disorders (ICDs); however, the relationship between impulsivity and cognitive dysfunction remains unclear. This study investigated whether trait impulsivity associates with mild cognitive impairment (MCI), or is altered in a PD patient cohort with MCI. Methods. A total of 302 patients with idiopathic PD were recruited sequentially from three Australian Movement Disorder clinics. Based on cognitive scores, participants were divided into two groups, one defined as having mild cognitive impairment (PD-MCI; n = 113) and the other with normal cognitive function (PD-C; n = 189). Trait impulsivity was evaluated using the Barrett Impulsiveness Scale 11 (BIS-11). Total impulsivity scores, as well as subscale scores, were compared between PD-C and PD-MCI groups. Results. The PD-MCI cohort had significantly lower scores in all cognitive domains, and mirrored expected clinical differences in medication, motor symptoms, and disease duration, when compared to the PD-C cohort. Self-reported impulsivity was not significantly different between groups, nor was there a difference within first-order subscale scores: attention p=0.137, cognitive instability p=0.787, self-control p=0.503, cognitive complexity p=0.157, motor impulsivity p=0.559, or perseverance p=0.734 between the PD-MCI and PD-C groups. Conclusions. These findings suggest that impulsive traits and behaviors are independent of changes in cognitive state and are not altered in PD patients with mild cognitive impairment.

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Effects of educational background on verbal fluency task performance in older adults with Alzheimer's disease and mild cognitive impairment

International Psychogeriatrics ◽

10.1017/s1041610210000839 ◽

2010 ◽

Vol 22 (6) ◽

pp. 995-1002 ◽

Cited By ~ 9

Author(s):

Naoko Kawano ◽

Hiroyuki Umegaki ◽

Yusuke Suzuki ◽

Sayaka Yamamoto ◽

Nanaka Mogi ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Test Scores ◽

Verbal Fluency ◽

Educational Background ◽

Cognitive State ◽

Category Fluency ◽

Fluency Task ◽

Fluency Test

ABSTRACTBackground: Previous studies have shown that the verbal fluency test (VFT) is a sensitive measure of cognitive dysfunction in Alzheimer's disease (AD). However, other studies have shown that the performances were significantly influenced by education in the normal elderly population. In order to examine the utility of the VFT as a tool for screening for AD, it is necessary to study the effect of education not only in the cognitively intact population but also in the population of early AD patients.Methods: Patients with AD (n = 345) and individuals with amnestic type of mild cognitive impairment (MCI) (n = 123) were asked to generate as many words as possible belonging to a category “animal” and beginning with “か [ka]” in syllabic Japanese “kana” script. In order to determine the education effect after adjusting for age and cognitive state on the VFT performance in early stage of AD, we performed multiple regression analysis with 396 individuals including both amnestic MCI and AD.Results: After adjusting for patients’ age, sex, and cognitive state, the years of education were significantly related to category fluency test scores, but not significantly related to letter fluency test scores.Conclusion: Our results demonstrated that a category fluency performance reflected not only AD-specific changes but also educational background. These results suggest the limitation of using the category fluency task for screening subjects at risk for developing AD without taking subjects' educational background into consideration.

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