The Patterns of Antihypertensive Drugs use in Acute Hemorrhagic Stroke Patients

2020 ◽  
Vol 13 (2) ◽  
pp. 547
Author(s):  
Din Amalia Widyaningrum ◽  
Wenny Putri Nilamsari ◽  
Wardah Rahmatul Islamiyah ◽  
Dewi Wara Shinta
Author(s):  
Dedi Sutia ◽  
Syarif Indra ◽  
Hendra Permana ◽  
Andi Fadilah Yusran Putri ◽  
Ribka Ankashima Sembiring

ELECTROCARDIOGRAM INTERPRETATION ABNORMALITIES ACCORDING TO NEUROIMAGING IN HEMORRHAGIC STROKEABSTRACTIntoduction: Stroke is the third leading cause of death in the world (about 30% of cases of stroke are hemorrhagic). Cardiovascular disease has correlation to stroke, as risk factor and complication leading to mortality.Aim: To describe electrocardiogram (ECG) interpretation abnormalities in acute hemorrhagic stroke patients.Methods: This retrospective descriptive study evaluated the archive data of acute hemorrhagic stroke patients neurology ward General Hospital of Dr. M. Djamil Padang who according to inclusion and exclusion criteria since 1st February to 30th September 2018. The samples were an electrocardiography of acute hemorrhagic stroke patients. Data were analyzed by univariate analysis using statistical package for the social science (SPSS) software 23.Results: This study administered 81 subjects; 34 subjects (41.98%) were male and 47 subjects (58.02%) were female. The highest age group was 61-70 years old (29.63%). Most common risk factor was hypertension (66.68%). There were 40 intracerebral hemorrhage (ICH) subjects (49.38%) and 7 subarachnoid hemorrhage (SAH) subjects (11.11%) who had ECG interpretation abnormality. Both groups had left ventricle hypertrophy (LVH) as the most common ECG interpretation abnormality (ICH: 40.76%, SAH: 3.73%). The only one of ICH with secondary SAH subject had ECG interpretation abnormality.Discussion: Abnormal electrocardiogram interpretation were more common than normal electrocardiogram interpretation in acute hemorrhagic stroke subjects. Left ventricle hypertrophy (LVH) is the most common ECG interpretation abnormality in acute hemorrhagic stroke subjects.Keywords: ECG abnormalities, hemorrhagic stroke, intracerebral hemorrhage, subarachnoid hemorrhageABSTRAKPendahuluan: Stroke adalah penyebab kematian ketiga terbanyak di dunia (sekitar 30% kasus stroke adalah tipe stroke hemoragik). Masalah kardiovaskular berhubungan erat dengan stroke, sebagai faktor risiko dan komplikasi yang mengakibatkan mortalitas.Tujuan: Penelitian ini mendeskripsikan temuan abnormalitas interpretasi elektrokardiogram (EKG) menurut gambaran neuroimaging pada pasien stroke hemoragik akut.Metode: Penelitian deskriptif retrospektif ini mengevaluasi arsip data pasien stroke hemoragik akut di ruangan rawat inap neurologi ruangan rawat inap neurologi Rumah Sakit Umum Pusat Dr. M. Djamil, Padang yang sesuai dengan kriteria inklusi dan eksklusi sejak 1 Februari hingga 30 September 2018. Sampel penelitian adalah gambaran EKG pasien stroke hemoragik akut. Data dianalisis dengan analisis univariat menggunakan software statistical package for the social science (SPSS) 23.Hasil: Pada penelitian ini didapatkan 81 subjek; 34 subjek (41,98%) adalah laki-laki dan 47 subjek (58,02%) adalah perempuan. Kelompok usia subjek terbanyak adalah kelompok usia 61-70 tahun (29,63%). Faktor risiko terbanyak adalah hipertensi (66,68%). Ada 40 subjek perdarahan intraserebral (PIS) (49,38%) dan 7 subjek perdarahan subaraknoid (PSA) (11,11%) yang memiliki abnormalitas interpretasi EKG. Kedua kelompok subjek memiliki left ventricle hypertrophy (LVH) sebagai abnormalitas interpretasi EKG terbanyak (PIS:40,76%, PSA: 3,73%) Ada 1 subjek PIS dengan PSA sekunder (1,23%) dan subjek tersebut memiliki abnormalitas interpretasi EKG. Ada 14 subjek yang memiliki LVH sebagai abnormalitas interpretasi EKG dari 30,90% yang memiliki perdarahan stroke di kapsula interna (lokasi perdarahan terbanyak). Jumlah subjek dengan interpretasi EKG normal terbanyak adalah subjek dengan perdarahan di talamus.Diskusi: Left ventricle hypertrophy (LVH) adalah temuan abnormalitas interpretasi EKG terbanyak yang ditemukan pada subjek perdarahan stroke di kapsula interna (lokasi perdarahan terbanyak).  Jumlah subjek dengan interpretasi EKG normal terbanyak adalah subjek dengan perdarahan di talamus.Kata kunci: Abnormalitas EKG, perdarahan intraserebral, perdarahan subarakhnoid, stroke hemoragik


2020 ◽  
pp. 9-14
Author(s):  
Mahfuj-Ul Anwar ◽  
Sajeda Afrin ◽  
ASM Rahenur Mondol ◽  
Mohammad Nurul Islam Khan ◽  
Narayan Chandra Sarkar ◽  
...  

Background: Stroke is a leading cause of mortality and disability worldwide. To prevent complications and permanent defects, early diagnosis, distinguishing the type and risk factor of stroke is crucial. Methodology: It was a hospital based cross sectional study, purposive sampling method was used, and a total of 469 stroke patients admitted into Department of Medicine, Rangpur medical college hospital, Bangladesh were included in this study. Results: In this study we have studied of 469 acute stroke patients. Among them 81% (380) were ischemic stroke patients and 19% (89) were hemorrhagic stroke. Overall male were more than female 308 (65.7%) vs 161(34.4%). The mean age for the ischemic stroke group was 64.1 ± 10.9 years, which was significantly higher than that of the hemorrhagic group (59.8 ± 9.60years) (P<0.05). Acute hemorrhagic stroke patients presented with acute onset of focal neurological deficit 61.8%, headache 64%, vomiting 59.6%, alteration of consciousness 48.3% and convulsion 27%. On the other hand, acute ischemic stroke patient presented with alteration of consciousness 65.5%, acute onset of focal neurological deficit 39.5%, paralysis 41%, deficit after awakening 32.4% and aphasia 34.7%. Among the risk factors of stroke in acute ischemic stroke patients hypertension was 59.2%, diabetes mellitus 20%, history of previous stroke 16.1%, ischemic heart disease 14.5% and atrial fibrillation 10.3% were present, on the other hand in acute hemorrhagic stroke patients hypertension 76.4%, smoking 70.8% and diabetes mellitus 6.7% were present. 26.97% of the acute hemorrhagic stroke and 13.9% of the acute ischemic stroke patients died in hospital. Conclusion: Common presentation of stroke was acute onset of focal neurological deficit; headache and vomiting were more in hemorrhagic stroke patient; alteration of consciousness, paralysis was predominant in ischemic stroke patient.


2009 ◽  
Vol 32 (5) ◽  
pp. 307 ◽  
Author(s):  
Huan Zhang ◽  
Zhong Ju ◽  
Tan Xu ◽  
Weijun Tong ◽  
Erdunchaolu Jin ◽  
...  

Purpose: To study the association between blood pressure (BP) SBP, DBP, mean arterial pressure (MAP) and pulse pressure (PP) and clinical outcome in acute hemorrhagic stroke patients in the Chinese population. Methods: 1,760 hemorrhagic stroke patients admitted to six hospitals from January 1, 2003 to December 31, 2005 were included in the study. BP and other variables were collected within the first 24-hr of admission. Clinical outcomes at discharge were evaluated by neurologists. Multivariate-adjusted odds ratios associated with increment of 1 standard deviation (SD) mmHg in four BP were determined by multiple logistic regression analysis. Results: The four BP indexes at admission were positively associated with death and SBP, DBP, MAP were associated with dependency. Adjusted odds ratios (95% confident interval) of death associated with increment of 1 SD mmHg were 1.74 (1.44,2.12), 1.39 (1.15,1.69),1.61 (1.32,1.96) and 1.66 (1.39,1.99) for SBP, DBP, MAP and PP, respectively (all P < 0.01), and adjusted odds ratio of dependency associated with increment of 1 SD mmHg was 1.15 (1.03,1.27), 1.21 (1.09,1.34) and 1.19 (1.07,1.32) for SBP, DBP and MAP, respectively (all P < 0.05). Conclusion: Increased SBP, DBP, MAP and PP at admission were all associated with in-hospital mortality, and increased SBP, DBP and MAP were associated with dependency at discharge among hemorrhagic stroke patients.


2021 ◽  
pp. 194187442098598
Author(s):  
Ibrahim Migdady ◽  
Aaron Shoskes ◽  
Leen Z. Hasan ◽  
Catherine Hassett ◽  
Pravin George ◽  
...  

Background and Purpose: The association between SARS-CoV-2 infection and stroke remains unknown. We aimed to compare the characteristics of stroke patients who were hospitalized with Coronavirus Disease 2019 (COVID-19) based on the timing of stroke diagnosis. Methods: We performed a retrospective analysis of adult patients in a health system registry of COVID-19 who were hospitalized and had imaging-confirmed acute stroke during hospitalization. Baseline characteristics and hospital outcomes were collected and analyzed. Results: Out of 882 COVID-19 patients who were hospitalized between March 9 to May 17, 2020, 14 patients (2% of all COVID-19 patients and 21% of those who underwent imaging) presented with stroke or developed stroke during hospitalization. Eleven had acute ischemic stroke (AIS) and 3 had acute hemorrhagic stroke. Six patients (43%) presented to the hospital with acute stroke symptoms and were found to have SARS-CoV-2. Compared to patients who presented with AIS, more patients with AIS during hospitalization were male, of older age, had pneumonia and acute respiratory distress syndrome, were severely ill, and had high inflammatory and thrombotic markers (including C reactive protein, D dimer, ferritin, and fibrinogen). Among all patients, hospital mortality was high (50%) and the majority of patients who were discharged had poor neurological outcome. Conclusions: A distinction should be made between patients who present with acute stroke with concurrent SARS-CoV-2 infection and those who develop stroke as a complication of severe COVID-19. It is likely that a subset of stroke patients will incidentally test positive for the virus given the widespread pandemic.


2013 ◽  
Vol 154 (44) ◽  
pp. 1743-1746
Author(s):  
Gergely Hofgárt ◽  
Rita Szepesi ◽  
Bertalan Vámosi ◽  
László Csiba

Introduction: During the past decades there has been a great progress in neuroimaging methods. Cranial computed tomography is part of the daily routine now and its use allows a fast diagnosis of parenchymal hemorrhage. However, before the availability of computed tomography the differentiation between ischemic and hemorrhagic stroke was based on patient history, physical examination, percutan angiography and cerebrospinal fluid sampling, and the clinical utility could be evaluated by autopsy of deceased patients. Aim: The authors explored the diagnostic performance of cerebrospinal fluid examination for the diagnosis of ischemic and hemorrhagic stroke. Method: Data of 200 deceased stroke patients were retrospectively evaluated. All patients had liquor sampling at admission and all of them had brain autopsy. Results: Bloody or yellowish cerebrospinal fluid at admission had a positive predictive value of 87.5% for hemorrhagic stroke confirmed by autopsy, while clear cerebrospinal fluid had positive predictive value of 90.7% for ischemic stroke. Patients who had clear liquor, but autopsy revealed hemorrhagic stroke had higher protein level in the cerebrospinal fluid, but the difference was not statistically significant (p = 0.09). Conclusions: The results confirm the importance of pathological evaluation of the brain in cases deceased from cerebral stroke. With this article the authors wanted to salute for those who contributed to the development of the Hungarian neuropathology. In this year we remember the 110th anniversary of the birth, and the 60th anniversary of the death of professor Kálmán Sántha. Professor László Molnár would be 90 years old in 2013. Orv. Hetil., 154 (44), 1743–1746.


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