scholarly journals Redefining Role of 5-Fluorouracil and Exploring the Impact of Taxanes and Cisplatin in Locally Advanced and Recurrent Carcinoma Cervix in Concurrent Setting With Radiotherapy: A Literature Review

Cureus ◽  
2020 ◽  
Author(s):  
Jasmeet Kaur ◽  
Sapna Marcus ◽  
Shreya Garg ◽  
Anju Kansal
Keyword(s):  
Literature Review ◽  
Locally Advanced ◽  
Carcinoma Cervix ◽  
Recurrent Carcinoma ◽  
The Impact

Stages of the formation of temporary and permanent occlusion and the impact of early tooth extraction on the dentition state. Literature review

2019 ◽  
pp. 22-24
Author(s):  
G.A. Murachueva ◽  
I.M. Rasulov ◽  
S.G. Gusenov
Keyword(s):  
Literature Review ◽  
Temporomandibular Joint ◽  
Tooth Extraction ◽  
Physiological State ◽  
Review Of The Literature ◽  
Full Development ◽  
Permanent Occlusion ◽  
The Impact

A review of the literature on the stages of the formation of temporary and permanent occlusion has been performed. This stages play an important role not only for the full development of the maxillofacial apparatus, temporomandibular joint, but also the whole organism. The role of early tooth extraction in the formation of the physiological state of the dentoalveolar system is considered. The conclusion is drawn about the need for a deeper study of this problem in the structure of general dental morbidity.

scholarly journals The impact of tumour regression in locally advanced carcinoma cervix during external beam radiotherapy and the need for adaptive planning

2016 ◽  
Keyword(s):  
Ct Scan ◽  
Locally Advanced ◽  
Target Volume ◽  
Ct Images ◽  
Tumour Regression ◽  
Target Coverage ◽  
Carcinoma Cervix ◽  
Advanced Carcinoma ◽  
The Impact ◽  
Planning Ct

Aim: To study the impact of tumour regression occurring during IMRT for locally advanced carcinoma cervix and study dose distribution to target volume and OARs and hence the need for any replanning. Materials and Methods: 40 patients undergoing IM-IGRT and weekly chemotherapy were included in the study. After 36 Gy, a second planning CT-scan was done and target volume and OARs were recontoured. First plan (non-adaptive) was compared with second plan (adaptive plan) to evaluate whether it would still offer sufficient target coverage to the CTV and spare the OARs after having delivered 36 Gy. Finally new plan was created based on CT-images to investigate whether creating a new treatment plan would optimize target coverage and critical organ sparing. To measure the response of the primary tumour and pathologic nodes to EBRT, the differences in the volumes of the primary GTV and nodal GTV between the pretreatment and intratreatment CT images was calculated. Second intratreatment IMRT plans was generated, using the delineations of the intratreatment CT images. The first IMRT plan (based on the first CT-scan or non adaptive plan) was compared with second IMRT plan (based on the second CT-scan or adaptive plan). Results: 35% patients had regression in GTV in the range of 4.1% to 5%, 20% in the range of 1.1%-2%, 15% in the range of 2.1%-3% and 20% in the range of 6%-15%. There was significant mean decrease in GTV of 4.63 cc (p=0.000). There was a significant decrease in CTV on repeat CT done after 36 Gy by 23.31 cc (p=0.000) and in PTV by 23.31 cc (p=0.000). There was a statistically significant increase in CTV D98, CTV D95, CTV D50 and CTV D2 in repeat planning CT done after 36 Gy. There was no significant alteration in OARs doses. Conclusion: Despite tumour regression and increased target coverage in locally advanced carcinoma cervix after a delivery of 36 Gy there was no sparing of OARs. Primary advantage of adaptive RT seems to be in greater target coverage with non-significant normal tissue sparing.

Identifying the Role of Digital Technologies in Sport Spectators Customer Experiences through Qualitative Approach

2021 ◽  
Vol 8 (2) ◽  
pp. 141-160
Author(s):  
Ekaterina Glebova ◽  
Michel Desbordes
Keyword(s):  
Literature Review ◽  
Sport Management ◽  
New Technologies ◽  
Digital Technologies ◽  
Primary Data ◽  
Technological Transformation ◽  
Consumption Culture ◽  
International Sport ◽  
The Impact

The massive uptake of digital technologies has changed the way how fans and the sports service field communicate and interact. In the current paper, we would like to emphasize the role of technology holistically in sport spectators customer experiences (SSCX) as a "game-changer" marketing in sports and the digitalization of SSCX. In this paper, we aim to explore and qualitatively describe by interviewees verbatim how new technologies impact SSCX. It draws on the literature review, combined with the primary data collected on unstructured interviews with international sport management and technology experts (N=10). It brings sports marketing insights followed by examples from industry professionals. Iterative analysis of data combined with literature review let us achieve to outline the crucial points and trends of technological transformations in sports spectacle. We offer an updated perspective on the SSCX through the prism of the impact of digital technologies and reshaping sports consumption culture. To this end, we develop a conceptual model that captures the nature of modern SSCX influenced by digital technologies. Keywords: technological transformation, sports spectacle, customer experience, co-creation, connectivity

A literature review exploring the role of technology in business survival during the Covid-19 lockdowns

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Salma S. Abed
Keyword(s):  
Literature Review ◽  
Small Businesses ◽  
Design Methodology ◽  
Human Life ◽  
Critical Role ◽  
Business Survival ◽  
Content Type ◽  
The Impact ◽  
Business Sectors

Purpose The Covid-19 pandemic has affected every aspect of human life. Even though the pandemic length was not too long, a huge volume of research relating to Covid-19 has been published in different contexts. This paper aims to review the literature investigating the impact of Covid −19 on businesses generally and explore studies examining the technology role of business survival during the Covid-19 lockdowns specifically. Design/methodology/approach This study implemented the concept of a systematic review approach to review the literature that has been conducted in the business field during the Covid-19 crisis in general. Additionally, it looks into the research examining the role of technology in business survival in the Covid-19 crisis specifically. All studies were conducted in 2020. A total of 53 studies were identified and categorised into different themes. The research methods, theories and locations have also been analysed. Findings It was found that Covid-19 pandemic has affected all business sectors in several ways. Technology adoption has a critical role for business survival during the Covid-19 crises especially with small businesses. Very limited research has been conducted on the adoption of different technologies during the Covid-19 lockdowns. Originality/value This study presents the most frequent themes and topics that have been explored in the literature during the Covid-19 crisis in the business field. It highlights the methods used in addition to the theories and research locations present in this literature. Finally, it proposes the possible implications of this literature review.

The Role of the Individual in ICT Standardisation

2015 ◽  
pp. 244-261
Author(s):  
Kai Jakobs
Keyword(s):  
Literature Review ◽  
Social Shaping Of Technology ◽  
The Social ◽  
Social Shaping ◽  
Technical Factors ◽  
Standards Development ◽  
The Individual ◽  
The Impact

This chapter discusses the influence individuals have in the ICT standards development process. The chapter draws upon ideas underlying the theory of the Social Shaping of Technology (SST). Looking through the SST lens, a number of non-technical factors that influence ICT standards development are identified. A literature review on the role of the individual in ICT standards setting and a case study of the IEEE 802.11 Working Group (WG) show that in a standards body's WG, the backgrounds, skills, attitudes, and behaviour of the individual WG members are crucially important factors. Yet, the case study also shows that in most cases employees tend to represent the ideas and goals of their respective employer. The chapter observes that the non-technical factors are ignored all too often in the literature. It argues that a better understanding of the impact and interplay of these factors, specifically including the skills and attitudes of the WG members, will have significant implications both theoretical and managerial.

The Role of Family in Youth Opioid Misuse: A Literature Review

2019 ◽  
Vol 27 (4) ◽  
pp. 429-442 ◽  
Author(s):  
Lovdeep Kaur ◽  
Eman Tadros ◽  
Rikki Patton
Keyword(s):  
Literature Review ◽  
Opioid Misuse ◽  
Opioid Use ◽  
Treatment Development ◽  
Factors Affecting ◽  
Relative Paucity ◽  
Full Text Review ◽  
Negative Impacts ◽  
The Impact

Objective: With the opioid epidemic reaching declared a public health emergency in recent years, a synthesis of recent knowledge outlining the impact of opioid use disorders on youth and families is needed. To this aim, this exploratory literature review examined how the role of family is discussed in research on youth opioid misuse, with the goal of acting as a springboard for further research and treatment development that could mitigate the negative impacts opioids are having on families and youth. Method: Peer-reviewed journal articles between 2008 and 2018 were accessed through PsycINFO in March 2018. A total of 279 unduplicated articles were identified through the search. Upon abstract and full-text review, a total of 21 articles met criteria for inclusion in the systematic review. Findings: Overall, the role of the family in adolescent opioid misuse was not commonly discussed in the literature, with 21 of 279 (7.5%) of articles meeting inclusion criteria for the current study. In the included articles, the following major themes were identified: (1) family factors affecting adolescent opioid misuse behavior and (2) family’s role in treatment of adolescent opioid misuse. Conclusions: The review evidences there is a relative paucity of literature on relational variables and youth opioid misuse. More practice-based scholarship, as well as more rigorous clinical research, is needed to inform future steps for clinical processes, policy, and research.

scholarly journals A Conceptual Model Proposal: Universities as Culture Change Agents for Sustainable Development

2020 ◽  
Vol 12 (11) ◽  
pp. 4635 ◽  
Author(s):  
Małgorzata Dzimińska ◽  
Justyna Fijałkowska ◽  
Łukasz Sułkowski
Keyword(s):  
Sustainable Development ◽  
Literature Review ◽  
Conceptual Model ◽  
Culture Change ◽  
Change Agents ◽  
The Body ◽  
Quality Culture ◽  
The University ◽  
The Impact

This paper aims to propose a conceptual model that synthesizes the existing findings concerning universities as culture change agents for sustainable development. The model could serve as a guidance on how universities might get involved in the pro-SD activities. It also underlines the prerequisite of the quality culture that should be introduced within all the activities of universities to successfully act as culture change agents for SD. This paper builds upon the holistic and inter-disciplinary approach to demonstrate that SD does not happen in isolation and that the role of universities in its creation is significant. This study includes a literature review to contextualize the impact of universities on culture and their potential role in SD. The conclusions stemming from the literature review materialize in the proposal of the conceptual model of the university as the culture change agent for SD. The elaborated framework responds to the need for greater clarity, ordering and systematization of the role of universities in the processes of initiating, promoting and modelling the SD-oriented changes while appreciating the role of culture as an enabler, means of social change and a result of SD-focused interventions. The paper contributes to the body of knowledge by offering a novel perspective on the assumed interrelations between university, its quality culture, university main operations such as education, research and engagement with the society as well as the culture and the agency of stakeholders in the context of meeting the world’s current demands without compromising the needs of future generations.

scholarly journals MRI versus clinical assessment in staging and response evaluation in locally advanced cervix cancer patients treated with concurrent chemo-radiation in a tertiary cancer center: a prospective study

2017 ◽  
Vol 6 (2) ◽  
pp. 392
Author(s):  
Aravindh Sivanandan Anand ◽  
Mintu Mathew Abraham ◽  
Vipin George Kuriakose
Keyword(s):  
Prospective Study ◽  
Treatment Response ◽  
Locally Advanced ◽  
Cervix Cancer ◽  
External Beam Radiation ◽  
Carcinoma Cervix ◽  
Figo Staging ◽  
Mri Staging ◽  
Kappa Value

Background: Carcinoma cervix is staged most commonly with FIGO staging even though it has a number of pitfalls, for standardization of treatment and epidemiological purpose. The objectives of this prospective study are to evaluate the role of MRI in staging of locally advanced cervix cancer and correlate with the FIGO staging and to assess the role of MRI in evaluating treatment response.Methods: 58 biopsy proved locally advanced carcinoma cervix patients who satisfied the inclusion and exclusion criteria from January 2014 to October 2015 were recruited. After the standard pretreatment evaluation including MRI abdomen and pelvis patients were started on concurrent chemo-radiation. Pelvic External beam radiation (EBRT) to a dose of 45Gy/23 fractions for a period of 4.5 weeks with cisplatin 40mg/m2 weekly once. Followed by intracavitary brachytherapy HDR weekly once 7Gy/fraction x 3 fractions. Treatment response assessed as per RECIST criteria. As a part of follow up, three monthly clinical evaluation and 4-6 months MRI evaluation were done.Results: Agreement between MRI and clinical stage was evaluated by calculating the kappa value as the measure of agreement. The kappa value obtained was 0.18 which showed poor agreement between the two, while comparing clinical and MRI assessment with regard to treatment response, the kappa value obtained was 0.08 signifying poor agreement.Conclusions: Correlation of FIGO and MRI staging reveals significant discordance between the two and on further evaluation it is seen that MRI staging correlates well with the local recurrence of the disease.

scholarly journals The role of telecare in supporting the needs of elderly people

2007 ◽  
Vol 13 (6) ◽  
pp. 293-297 ◽  
Author(s):  
Simon Brownsell ◽  
Hazel Aldred ◽  
Mark S Hawley
Keyword(s):  
Literature Review ◽  
Elderly People ◽  
Expert Panel ◽  
Trigger Factors ◽  
Factors Associated ◽  
Levels Of Care ◽  
Care And Support ◽  
The Impact ◽  
Major Consideration

A literature review was conducted to identify the 'trigger factors' associated with a need for increased levels of care and support for elderly people. An expert panel then prioritized the trigger factors into one of five bands of importance. The literature review produced 2037 hits. Of these, 1768 were excluded after reading the abstract and 111 after reading the full paper, leaving 158 papers for inclusion in the review. From these papers, 102 unique factors that triggered a need for greater care and support among elderly people were identified. The expert panel ranked 36 of the trigger factors into the top three bands of importance. Subsequent analysis suggested that telecare could be used to assist, prevent or minimise the impact of some 66% of these 36 trigger factors and 75% of the top 12 factors. This suggests that telecare has a significant role to play in the support of elderly people and should be a major consideration when re-designing services.

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