Myocarditis Post Moderna Vaccination: Review of Criteria for Diagnosis

The Acromegaly Consensus Group redefined the consensus criteria for cure of acromegaly. 74 neurosurgeons and experienced endocrinologists summarized the latest results on diagnosis and treatment of acromegaly. In this consensus statement the reliable growth hormone and insulin-like growth factor-1 assays were established. Definition of disease control was discussed based on the available publications and evidence. This short communication summarizes the clinical aspects of consensus criteria for diagnosis and cure of acromegaly based on the original article. Orv. Hetil., 2011, 152, 703–708.

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187-OR: Randomized Clinical Trial of the IADPSG vs. Carpenter Coustan Criteria for Diagnosis of Gestational Diabetes Mellitus

Diabetes ◽

10.2337/db20-187-or ◽

2020 ◽

Vol 69 (Supplement 1) ◽

pp. 187-OR

Author(s):

CHRISTINA M. SCIFRES ◽

KALEAB ABEBE ◽

HYAGRIV SIMHAN ◽

PATRICK CATALANO ◽

TINA COSTACOU ◽

...

Keyword(s):

Diabetes Mellitus ◽

Clinical Trial ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Randomized Clinical Trial ◽

Criteria For Diagnosis

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Dukungan sosial dan kualitas hidup orang dengan HIV/AIDS

Berita Kedokteran Masyarakat ◽

10.22146/bkm.12563 ◽

2017 ◽

Vol 33 (3) ◽

pp. 147

Author(s):

Mardia Mardia ◽

Riris Andono Ahmad ◽

Bambang Sigit Riyanto

Keyword(s):

Quality Of Life ◽

Social Support ◽

Antiretroviral Therapy ◽

Social Life ◽

Opportunistic Infections ◽

People Living With Hiv ◽

Hiv Diagnosis ◽

Criteria For Diagnosis ◽

Hiv Aids

Purpose: This study aimed to determine the quality of life among people living with HIV/AIDS based on the criteria for diagnosis and other factors.Methods: This study was conducted in the VCT clinic hospital of Dr. Moewardi. The population was HIV-positive patients with antiretroviral therapy. Data collection conducted through medical records and interview to patients. Results: Out of a total of 89 respondents, 66.29% were males and 71.91% were aged between 26-45 years. We found significant correlations for diagnosis of HIV/AIDS, opportunistic infections, time since HIV diagnosis, duration of ARV therapy, social support, modes of transport, sex, age, and marital status with the quality of life. Multivariate analysis obtained by each variable showed the strongest association with the quality of life was time since diagnosis, social support and duration of ARV therapy. Conclusion: The quality of life was better for those who have been diagnosed with HIV/AIDS ≥ 32 months, with social support, and who have been undergoing antiretroviral therapy ≥ 29 months. Improved counseling in the early days of ARV therapy is necessary to always maintain the treatment and provide support for their social life.

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CT density of cervical thymus, in comparison with mediastinal thymus

Insights into Imaging ◽

10.1186/s13244-019-0781-z ◽

2019 ◽

Vol 10 (1) ◽

Author(s):

Anitha Sen ◽

Jiji Valsalamony ◽

Jubie Raj

Keyword(s):

Young Adults ◽

Soft Tissue ◽

Older Age ◽

List Type ◽

Age Group ◽

Positive Correlation ◽

Children And Young Adults ◽

Criteria For Diagnosis ◽

Ct Density ◽

Moderate Positive Correlation

Abstract Objectives Cervical component of thymus is noted more in children and young adults than in older age group. CT texture (lobules of soft tissue interspersed with fat), similarity with CT density of mediastinal thymus and continuity with mediastinal thymus on sagittal/coronal images, are given as the criteria for diagnosis of the cervical thymus. But CT densities of cervical and mediastinal components of the thymus may vary. The purpose of our study was to compare CT densities of cervical and mediastinal parts of the thymus, in cases where ultrasonography correlation was available. Methods We retrospectively identified 22 patients who had undergone CT between May 2015 and May 2017 and in whom ultrasonography (USG) correlation was available. CT densities of cervical and mediastinal components of thymus were measured. Results CT density of cervical thymus is lower than the CT density of mediastinal thymus by ~ 25 HU. There is a moderate positive correlation between CT densities of cervical and mediastinal parts of the thymus. CT densities of both cervical and mediastinal thymus were found to reduce with age, but the reduction was statistically significant only in the cervical thymus in this study. Conclusions CT densities of cervical and mediastinal components of the thymus may vary, with CT density of cervical thymus being lower. There is a positive correlation between CT densities of cervical and mediastinal parts of the thymus. CT density of cervical thymus reduces with age. Understanding these may help avoid confusion on CT and avoid the need for correlative USG, saving time and effort.

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Diagnostic tools for neurosyphilis: a systematic review

BMC Infectious Diseases ◽

10.1186/s12879-021-06264-8 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Gustavo Henrique Pereira Boog ◽

João Vitor Ziroldo Lopes ◽

João Vitor Mahler ◽

Marina Solti ◽

Lucas Tokio Kawahara ◽

...

Keyword(s):

New Technologies ◽

Clinical Suspicion ◽

Risk Of Bias ◽

Diagnostic Methods ◽

Diagnostic Tools ◽

Test Accuracy ◽

Cerebrospinal Fluid Analysis ◽

Evaluation Methodologies ◽

Fluid Analysis ◽

Criteria For Diagnosis

Abstract Purpose Increasing incidences of syphilis highlight the preoccupation with the occurrence of neurosyphilis. This study aimed to understand the current diagnostic tools and their performance to detect neurosyphilis, including new technologies and the variety of existing methods. Methods We searched databases to select articles that reported neurosyphilis diagnostic methods and assessed their accuracy, presenting sensitivity and specificity values. Information was synthesized in tables. The risk of bias was examined using the Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy recommendations. Results Fourteen studies were included. The main finding was a remarkable diversity of tests, which had varied purposes, techniques, and evaluation methodologies. There was no uniform criterion or gold standard to define neurosyphilis. The current basis for its diagnosis is clinical suspicion and cerebrospinal fluid analysis. There are new promising tests such as PCR tests and chemokine measurement assays. Conclusions The diagnosis of neurosyphilis is still a challenge, despite the variety of existing and developing tests. We believe that the multiplicity of reference standards adopted as criteria for diagnosis reveals the imprecision of the current definitions of neurosyphilis. An important next step for the scientific community is to create a universally accepted diagnostic definition for this disease.

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Calcitonin-Negative Neuroendocrine Carcinoma of the Thyroid Gland: Case Report and Literature Review

Case Reports in Oncology ◽

10.1159/000510807 ◽

2021 ◽

pp. 112-122

Author(s):

Ricardo Fernández-Ferreira ◽

Ildefonso Roberto De la Peña-López ◽

Karla Walkiria Zamudio-Coronado ◽

Luis Antonio Delgado-Soler ◽

María Eugenia Torres-Pérez ◽

...

Keyword(s):

Thyroid Carcinoma ◽

English Language ◽

Neoadjuvant Treatment ◽

Complete Response ◽

Cervical Region ◽

Proliferation Index ◽

Ki 67 ◽

Definitive Evidence ◽

Criteria For Diagnosis ◽

Fdg Pet Ct

Calcitonin-negative neuroendocrine tumor (CNNET) of the thyroid is an extremely rare entity. In some of the previously reported cases within the literature, the terms “atypical medullary thyroid carcinoma,” “calcitonin-free oat cell carcinoma,” and “a distinct clinical entity” were applied to NETs without definitive evidence of calcitonin production. In the English-language literature, not only are there only few reported cases of CNNET, but the criteria for diagnosis in these cases are also controversial. Most of the current published cases were also treated surgically for local disease. We describe a case of NET of the thyroid with calcitonin, chromogranin A and thyroglobulin negativity, synaptophysin and TTF-1 positivity, and a high Ki-67 proliferation index with metastases in the cervical region as well as mediastinal adenopathies. This case was considered an unresectable thyroid carcinoma, and chemotherapy including cisplatin and etoposide was started as neoadjuvant treatment at the department of medical oncology. Total thyroidectomy plus bilateral and central cervical dissection was performed, and the patient underwent 2 cycles of adjuvant radiotherapy. Currently, the patient’s 18F-FDG-PET/CT findings show a complete response 17 months after diagnosis. In conclusion, CNNET of the thyroid is very rare and there is limited evidence regarding treatment in patients with metastases. Chemotherapy including cisplatin and etoposide as well as early aggressive surgical resection appears to positively impact patients’ survival.

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