Variation in Content of Marker Compounds and Quality of Processed White Ginseng of Different Cultivation Ages from Different Regions

2018 ◽  
Vol 26 (5) ◽  
pp. 408-416
Author(s):  
Ki Yeul Nam ◽  
Gwang Bo Hwang ◽  
Dae Young Lee ◽  
Jin Soo Han ◽  
Hyung Jun Noh ◽  
...  
Keyword(s):  
White Ginseng ◽  
Marker Compounds

scholarly journals Chromatographic fingerprints and quantitative analysis for the quality evaluation of Bao-Yuan Decoction by ultra-performance liquid chromatography coupled with diode array and evaporative light scattering detection

2021 ◽  
Author(s):  
Min Zhang ◽  
Zhenling Zhu ◽  
Mengyue Wang ◽  
Jincai Hou ◽  
Yinqing Li ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Light Scattering ◽  
Ultra Performance Liquid Chromatography ◽  
Dosage Forms ◽  
Diode Array ◽  
Evaporative Light Scattering Detection ◽  
Light Scattering Detection ◽  
Evaporative Light Scattering ◽  
Marker Compounds

AbstractBao-Yuan Decoction (BYD), a widely used traditional Chinese medicine formula, is worth developing into modern dosage forms. To assess the quality of traditional decoction, the commonly used ultra-performance liquid chromatography coupled with diode array and evaporative light scattering detection (UPLC-DAD/ELSD) method was initially applied to develop the analytical methods for the qualitative fingerprints and simultaneous quantitation of multiple marker compounds in BYD. Based on 16 batches of BYD prepared from multiple batches of qualified crude herbs combined randomly, the characteristic fingerprints were generated, with 41 and 19 common peaks detected by DAD and ELSD, respectively. Furthermore, ginsenosides Re, Rg1 and Rb1, calycosin-7-glucoside, calycosin, liquiritin, isoliquiritin apioside, isoliquiritin, glycyrrhizic acid and cinnamic acid were qualified as marker compounds to represent the herbs composing the formula. The characteristic fingerprints and the content ranges of multiple batches of the decoction were obtained, thus providing guidance for the quality control of modern dosage forms. The combination of these qualitative and quantitative methods will be an effective operational measure by which to evaluate and control the quality of BYD from traditional decoction to modern dosage forms.

scholarly journals Evaluation of the Quality of Chinese and Vietnamese Cassia Using LC-MS and Multivariate Analysis

2013 ◽  
Vol 8 (1) ◽  
pp. 1934578X1300800
Author(s):  
Ken Tanaka ◽  
Feng Li ◽  
Yasuhiro Tezuka ◽  
Shiro Watanabe ◽  
Nobuo Kawahara ◽  
...  
Keyword(s):  
Principal Component Analysis ◽  
Multivariate Analysis ◽  
Chemical Composition ◽  
Herbal Medicine ◽  
Principal Component ◽  
The Other ◽  
Chemical Composition Of Water ◽  
Different Types ◽  
Marker Compounds

In the present study, the chemical composition of water extracts of Chinese and Vietnamese cassia (Cinnamomum cassia) were compared using multivariate analysis of LC-MS data. By principal component analysis of the LC-MS data, 6 compounds, cinnzeylanine (1), cinnzeylanol (2), anhydrocinnzeylanol (3), cinncasinol A (4), epicatechin (5) and procyanidin B2 (6), were identified as the marker compounds to characterize Chinese and Vietnamese cassia. It was clarified that Chinese cassia contains relatively larger amounts of epicatechin and procyanidin B2. On the other hand, Vietnamese cassia is characterized by a relatively larger amount of diterpenes. As catechin derivatives and diterpenes have different types of activity, it is important to choose the cassia that best suits the product for which it is to be used, whether in food or in herbal medicine.

scholarly journals Simultaneous Analysis to Evaluate the Quality of Insamyangpye–Tang Using High-Performance Liquid Chromatography–Photo Diode Array Detection

2021 ◽  
Vol 11 (11) ◽  
pp. 4819
Author(s):  
Chang-Seob Seo ◽  
Mee-Young Lee
Keyword(s):  
Quality Control ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Phase System ◽  
Analysis Method ◽  
Marker Compounds ◽  
Array Detection ◽  
Basic Quality

Insamyangpye–tang (ISYPT) is a traditional medicinal formula comprised of 13 herbs and has been used in East Asia to treat lung-related diseases. However, to our knowledge, no method of analysis for its quality control has been reported. In this study, a method of analysis for quality control of ISYPT was developed using high-performance liquid chromatography. Chromatographic separation, analysis, and assay verification were performed with a distilled water–acetonitrile mobile phase system, both containing 0.1% (v/v) trifluoroacetic acid, and a Gemini C18 analytical column (4.6 mm × 250 mm, 5 mm) using authentic standards for eight marker compounds. These marker constituents were detected simultaneously at 0.09–5.95 mg/g. The analysis method developed can be used for basic quality control of ISYPT.

scholarly journals Improvement of Hygienic Quality of White Ginseng Powders by .GAMMA.-lrradiation.

RADIOISOTOPES ◽  
1994 ◽  
Vol 43 (12) ◽  
pp. 750-759 ◽  
Author(s):  
Han-Ok CHO ◽  
Myung-Woo BYUN ◽  
Il-Jun KANG ◽  
Hong-Sun YOUK ◽  
Joong-Ho KWON
Keyword(s):  
Hygienic Quality ◽  
White Ginseng

scholarly journals Preliminary Study on the Effect of Nitrogen Fertilisation on Phytochemical Content Quality of Gynura procumbens

2021 ◽  
Vol 32 (3) ◽  
pp. 69-96
Author(s):  
Mohamad Fhaizal Mohamad Bukhori ◽  
Hawa Jaafar ◽  
Ali Ghasemzadeh ◽  
Uma Rani Sinniah ◽  
Gayatri Karipaya
Keyword(s):  
Block Design ◽  
Plant Quality ◽  
Phytochemical Content ◽  
Content Quality ◽  
Two Factors ◽  
Marker Compounds ◽  
Three Stages ◽  
Preliminary Study ◽  
Physiological And Biochemical

The study was carried out to examine the effects of nitrogen (N) fertilisation on phytochemical content quality, to determine types of phytochemicals compositions, and to establish phytochemicals marker compounds in Gynura procumbens. In this two factors study, three stages of harvesting (H) time and three rates of N were laid out according to Randomised Complete Block Design (RCBD). Physiological and biochemical attributes were recorded to exhibit the trend for plant quality. The results showed that, N has affected phytochemical content significantly (p < 0.05) with stronger effect on physiological and biochemical attributes (p < 0.01). The results suggested that 0 and 90 kg/ha N, respectively are highly and least effecting the Photo, Cond, TChlC, TCC, TPrc, TLiC, TPC and TFC.

scholarly journals Differentiation of Polyamide 6, 6.6, and 12 Contaminations in Polyolefin-Recyclates Using HPLC Coupled to Drift-Tube Ion- Mobility Quadrupole Time-of-Flight Mass Spectrometry

Polymers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2032
Author(s):  
Andrea Schweighuber ◽  
Jörg Fischer ◽  
Wolfgang Buchberger
Keyword(s):  
Cross Section ◽  
Ion Mobility ◽  
Drift Tube ◽  
Collision Cross Section ◽  
Polyamide 6 ◽  
Flight Mass Spectrometry ◽  
Marker Compounds ◽  
A Current

Recycling is a current hot topic with a focus especially on plastics. The quality of such plastic recyclates is of utmost importance for further processing because impurities lead to a reduction thereof. Contaminations originating from other polymers are highly problematic due to their immiscibility with the recyclate, leading to possible product failures. Therefore, methods for the determination of polymer impurities in recyclates should be investigated. In this paper, an approach for the identification of three different polyamide grades (polyamide 6, 6.6, and 12) is presented, applicable for the analysis of polyolefin-recyclates. An HPLC equipped with a drift-tube ion-mobility QTOF-MS was used for the identification and differentiation of compounds originating from the polyamides, which were then used as markers. These marker compounds are specific for each type and can be identified by their corresponding value of the collision cross section (CCS). After a simple sample preparation, all three types of polyamides were identified within one measurement. In particular, the problematic differentiation of polyamide 6 and 6.6 was easily made possible.

scholarly journals UPLC-QTOF/MS-Based Metabolomics Applied for the Quality Evaluation of Four Processed Panax ginseng Products

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 2062 ◽  
Author(s):  
Jae Lee ◽  
Seung-Heon Ji ◽  
Bo-Ram Choi ◽  
Doo Choi ◽  
Yeong-Geun Lee ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
Quality Evaluation ◽  
Principal Component ◽  
Ultra Performance Liquid Chromatography ◽  
Flight Mass Spectrometry ◽  
Black Ginseng ◽  
White Ginseng ◽  
Well Differentiated ◽  
And Control

In the food industry and herbal markets, it is critical to control the quality of processed Panax ginseng products. In this study, ultra-performance liquid chromatography coupled to quadrupole time of flight mass spectrometry (UPLC-QTOF/MS)-based metabolomics was applied for the quality evaluation of white ginseng (WG), tae-geuk ginseng (TG), red ginseng (RG), and black ginseng (BG). Diverse metabolites including ginsenosides were profiled by UPLC-QTOF/MS, and the datasets of WG, TG, RG, and BG were then subjected to multivariate analyses. In principal component analysis (PCA), four processed ginseng products were well-differentiated, and several ginsenosides were identified as major components of each product. S-plot also characterized the metabolic changes between two processed ginseng products, and the major ginsenosides of each product were found as follows: WG (M-Rb1, M-Rb2, M-Rc, Re, Rg1), TG (Rb2, Rc, Rd, Re, Rg1), RG (Rb1, Rb2, Rc, Rd, Re, Rg1), and BG (Rd, Rk1, Rg5, Rg3). Furthermore, the quantitative contents of ginsenosides were evaluated from the four processed ginseng products. Finally, it was indicated that the proposed metabolomics approach was useful for the quality evaluation and control of processed ginseng products.

Comparative effects of gamma irradiation and phosphine fumigation on the quality of white ginseng

2000 ◽  
Vol 57 (3-6) ◽  
pp. 309-313 ◽  
Author(s):  
Joong-Ho Kwon ◽  
Myung-Woo Byun ◽  
Kang-Soo Kim ◽  
Il-Jun Kang
Keyword(s):  
Gamma Irradiation ◽  
White Ginseng

scholarly journals Chemical Analysis of the Principal Flavonoids of Radix Hedysari by HPLC

2010 ◽  
Vol 5 (4) ◽  
pp. 1934578X1000500
Author(s):  
Yi Liu ◽  
Yuying Zhao ◽  
Hubiao Chen ◽  
Bin Wang ◽  
Qingying Zhang
Keyword(s):  
Chemical Analysis ◽  
Chemical Quality ◽  
Factors Affecting ◽  
Harvesting Time ◽  
Processing Procedure ◽  
Marker Compounds ◽  
Almost All ◽  
Different Origins

Five major flavonoids in 48 batches of Radix Hedysari from different origins have been simultaneously evaluated by HPLC. Among the five major flavonoids, four, ononin, formononetin-7- O-β-D-glucopyranoside-6″- O-malonate, formononetin and medicarpin, were detected in almost all the samples and thus can be used as marker compounds to evaluate the chemical quality of Radix Hedysari, while naringin was not suitable because it was not be detected in most samples. Further analysis of the contents of the four flavonoids in different samples showed that processing procedure, harvesting time and habitats were important factors affecting the flavonoid contents of Radix Hedysari.

Sign in / Sign up

Export Citation Format

Share Document