scholarly journals PHYSICO CHEMICAL EVALUATION OF NEELIBHRINGADI KERA TAILAM MANUFACTURED BY AYURVEDIC COMPANIES IN KERALA

2021 ◽  
Vol 12 (11) ◽  
pp. 13-17
Author(s):  
Reshmi A ◽  
Thara Lakshmi S

The quality control of herbal medicines has become a major concern to health authorities, health care providers and the manufacturing industries at every stage of production. The standardization of raw drugs and formulations with the help of modern analytical tools increase their scope, acceptance and scientific validity. The safety and efficacy of herbal medicines largely depend on their quality. Neelibhringadi keratailam is an excellent hair growth promoting oil widely prescribed and marketed in Kerala. All the ingredients in the formulation are best hair growth promoters. The knowledge of hair products, their mode of action, efficacy and ingredients has become more relevant today. Neelibhringadi keratailam manufactured by GMP certified Ayurvedic companies in Kerala was assessed by evaluating and comparing the physico chemical parameters of market samples of Neelibhringadi keratailam with that of prepared Neelibhringadi keratailam. Physico chemical parameters such as Acid value (AV), Iodine value (IV), Refractive index (RI) Saponification value (SV), Specific gravity (SG), Weight per milliliter, HPTLC, ICP-MS and microbial contamination of market samples were evaluated and compared with those of prepared sample. Neelibhringadi keram was prepared and its physicochemical analysis was done and compared with market samples. Analysis of the market samples showed significant variation in physicochemical analytical parameters, colour and consistency from the prepared samples.

2014 ◽  
Vol 4 (1) ◽  
pp. 25-38
Author(s):  
Alissa D. Koski ◽  
Ellie Mirzabagi ◽  
Patience Cofie ◽  
Vandana Tripathi

PURPOSE: Uterotonic drugs, administered immediately after delivery, can prevent postpartum hemorrhage (PPH). As programs expand uterotonic access in settings of high maternal mortality, it is important to understand why and how these drugs are currently used. This qualitative study aimed to describe Ghanaian health care providers’ and community members’ knowledge, perceptions, and practices of uterotonic usage at or near labor and delivery.METHODS: In-depth interviews were conducted in 3 districts with 185 physicians, medical assistants, midwives, nurses, new mothers, mothers aged 50 years and older, traditional birth attendants, and chemists.FINDINGS: Providers described using misoprostol most commonly for labor induction, oxytocin for labor augmentation and PPH prevention, and ergometrine for PPH treatment. Unsafe practices and knowledge gaps were identified regarding labor augmentation and uterotonic storage. Community members reported experience with uterotonics in facility deliveries. Community-based use of pharmaceutical uterotonics was rarely reported, except misoprostol for pregnancy termination; however, community members described use of herbal medicines for intended uterotonic effect. Across respondent categories, uterotonics were more commonly associated with accelerating delivery than PPH prevention.CONCLUSION: Programs promoting facility childbirth and/or uterotonic coverage at home births should consider these underlying patterns of use and encourage safe practices through provider and community engagement.


2020 ◽  
Author(s):  
Anna Tengia Kessy ◽  
George Chombe Msalale

Abstract Background: In most sub-Sahara African countries, herbal medicines are widely used during pregnancy and labour for various motives despite their unclear pharmacology and potential toxicity. Considering the United Nations Sustainable Development Goal (SDG) 3, exposure to herbs during pregnancy should be restricted in order to safeguard the health of mothers and newborns. This study aimed to assess the proportion of mothers using herbal medicines during pregnancy and delivery and to determine factors associated with the practice.Methods: This cross-sectional quantitative study gathered information from 340 mothers who delivered a live baby in the preceding two years. Using a two-stage-sampling technique, we selected and interviewed mothers attending reproductive, maternal and child health clinics in Tabora, in central Tanzania. We compared proportions using chi-square test and performed a Poisson regression analysis to determine independent correlates of herbal use.Results: Over 60% of mothers in Tabora used herbal medicines during pregnancy and delivery. Major reasons for use were shortening of labour duration, 81 (38.9%) and reducing labour pain, 58 (27.9%). Independent factors of herbal use were distance to the nearest health facility, adjusted prevalence ratio (aPR = 1.12, 95%CI = 1.00,1.25), perception of herbs as safe, (aPR = 1.16, 95%CI = 1.05,1.29) and health care providers’ stance on the use of herbs, (aPR = 1.14, 95%CI = 1.04,1.25).Conclusions: Use of herbal medicines during pregnancy and delivery in Tanzania is high. This calls for comprehensive investigations on the effects of herbs used during pregnancy and delivery as a step towards understanding contributions of forgotten exposures en route for achieving SDG 3. Additionally, health care providers ought to include health education messages during antenatal visits on the undesirable effects of using herbs.


Author(s):  
AMAD M. AL-AZZAWI ◽  
NEHAD MEHDI ◽  
ALYAA G. AL-JUBOORI ◽  
ANAM EJAZ ◽  
HANEEN ALI ◽  
...  

Objective: The aim of this study was to assess the perceptions of different healthcare professionals towards HM. Methods: The 16-item questionnaire on the belief of health care professionals in herbal medicine was designed by the interdisciplinary task force. Eligible participants were health care providers who were English-and Arabic-literate. The response rate was 78% of participants (781 of 1000) were respondents. In total, 553 out of 781 (71%) participants indicated that they had previously used herbal medicines. The remaining 228 participants did not believe in herbal medicine due to lack of scientific evidence, ineffectiveness and other reasons. Results: The findings of this study indicate that health care professionals including pharmacists believe they have a responsibility to provide information on HM to their patients. However, the current consensus among the respondents is that current HM-focused knowledge is inadequate for such an application. Conclusion: Health care professionals believe in using HM for their needs and have a responsibility to provide information on HM to their patients.


2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
N. El Boulifi ◽  
A. Bouaid ◽  
M. Martinez ◽  
J. Aracil

Response surface methodology (RSM) based on central composite design (CCD) was used to optimize biodiesel production process from corn oil. The process variables, temperature and catalyst concentration were found to have significant influence on biodiesel yield. The optimum combination derived via RSM for high corn oil methyl ester yield (99.48%) was found to be 1.18% wt catalyst concentration at a reaction temperature of55.6∘C. To determine how long biodiesel can safely be stored, it is desirable to have a measurement for the stability of the biodiesel against such oxidation. Storage time and oxygen availability have been considered as possible factors influencing oxidative instability. Biodiesel from corn oil was stored for a period of 30 months, and the physico-chemical parameters of samples were measured at regular interval of time. Results show that the acid value (AV), peroxide value (PV), and viscosity (ν) increased while the iodine value (IV) decreased. These parameters changed very significantly when the sample was stored under normal oxygen atmosphere. However, theν, AV, and IV of the biodiesel sample which was stored under argon atmosphere were within the limit by the European specifications (EN 14214).


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Anna Tengia-Kessy ◽  
George Chombe Msalale

Abstract Background In most of the sub-Sahara African countries, use of herbal medications is widely practiced during pregnancy or delivery for various reasons despite uncertainties on their pharmacological profiles. Use of unregistered herbal medicines has the potential of causing adverse health effects to the mother and the newborn, thus deterring achievement of Sustainable Development Goal 3, which aims to “ensure healthy lives and promote well-being for all at all ages”. One of the targets is on reduction of morbidity and mortality among mothers and newborns. This study investigated use of herbal medicines and predictors of usage during pregnancy or delivery as a forgotten exposure towards understanding some of the challenges in achieving Sustainable Development Goal 3. Methods This cross-sectional quantitative study gathered information from women who delivered a live-born baby in the preceding two years. Using a two-stage-sampling technique, women attending reproductive, maternal and child health clinics in Tabora were selected and interviewed. Proportions were compared using chi-square test and Poisson regression analysis was performed to determine independent correlates of herbal medicine use. Results Of 340 recruited women, 208 [61.2 %; 95 % confidence interval: 55.4, 66.3 %] used herbal medicines during pregnancy or delivery. Major reasons for use included accelerating labour, 81 (38.9 %) and reducing labour pains, 58 (27.9 %). Women who made less than four antenatal visits had a 24 % higher adjusted prevalence ratio of using herbal medicines as compared to those who had at least four visits [adjusted prevalence ratio:1.24; 95 % confidence interval: 1.02, 1.50, p = 0.03]. Furthermore, the adjusted prevalence ratio of using herbal medicines was 35 % higher among women who were not discouraged by health care providers against their use as compared to those who were discouraged (adjusted prevalence ratio: 1.35; 95 % confidence interval: 1.13, 1.60, p = 0.01). Conclusions Use of herbal medicines during pregnancy or delivery among women in Tanzania is common. Independent predictors of herbal medicine use were number of antenatal visits and stance of maternity health care providers on their use. Comprehensive investigations on the magnitude, patterns and predictors of use of herbal medicines during pregnancy or delivery are warranted.


2020 ◽  
Author(s):  
Anna Tengia Kessy ◽  
George Chombe Msalale

Abstract Background: In most sub-Sahara African countries, herbal medicines are widely used during pregnancy or delivery for various motives despite their unclear pharmacology and potential toxicity. All risky exposures, including use of herbs during pregnancy or delivery should be restricted in order to facilitate achieving the Sustainable Development Goal (SDG) 3: “ensure healthy lives and promote wellbeing for all including reduction of morbidity and mortality among mothers and newborns”. This study assessed use of herbal medicines during pregnancy or delivery and determined factors associated with the practice in Tabora, Tanzania.Methods: This cross-sectional quantitative study gathered information from 340 women who delivered a live-born baby in the preceding two years. Using a two-stage-sampling technique, we selected and interviewed women attending reproductive, maternal and child health clinics in public health facilities in Tabora, central Tanzania. We compared proportions using chi-square test and performed a Poisson regression analysis to determine independent correlates of herbal use.Results: Of 340 recruited women, 208 (61.2 %; 95%CI: 55.4, 66.3%) used herbal medicines during pregnancy or delivery. Major reasons for use included shortening of labour duration, 81 (38.9%) and reducing labour pain, 58 (27.9%). The independent predictors of herbal use were number of antenatal visits and the stance of maternity health care providers on the use of herbs. Women who made less than four visits had 24% higher prevalence ratio of using herbal medicines as compared to those who made at least four visits (aPR:1.24; 95%CI: 1.02, 1.50, p=0.03). Furthermore, the adjusted prevalence ratio of using herbs was 35% higher among women who were not discouraged by the health care providers against using herbs versus those who were discouraged (aPR: 1.35; 95%CI: 1.13, 1.60, p=0.01). Conclusions: Use of herbal medicines during pregnancy or delivery in Tanzania is high. This calls for comprehensive investigations on the effects of using herbs during pregnancy or delivery as a step towards understanding some of the challenges in achieving SDG 3. Additionally, maternity health care providers ought to strengthen provision of health education messages during antenatal visits on the undesirable effects of using herbs.


2014 ◽  
Vol 30 (4) ◽  
pp. 705-715
Author(s):  
N. Stanisic ◽  
N. Parunovic ◽  
M. Petrovic ◽  
C. Radovic ◽  
S. Lilic ◽  
...  

The aim of this trial was to investigate changes in chemical and physico-chemical parameters during the production of traditional Sremska sausage (dry fermented sausage) from pork of three pig breeds: Mangalitsa (MA), Moravka (MO) and Swedish Landrace (SL). Analyses of all variants of sausages were carried out after stuffing (day 0) and on production days 3, 7, 14 and 21. The reduction in moisture during production caused the increase in protein, fat and ash contents (p<0.001) in all three variants of sausages, were found to be within the range for this type of sausages. Higher fat content in MA and MO sausages compared to SL variant was most likely a result of the different chemical composition of the meat from pigs of autochthonous breeds. All three sausage variants had a similar final pH value, but the mildest drop of pH was determined in MA sausages. Pig breed significantly affected (p<0.05) all three indicators of oxidative changes (thiobarbituric acid value, peroxide value and free fatty acid content). It was found that they were higher in SL compared with MA and MO sausages and to significantly increase during the production process.


Author(s):  
Maryam Babangida Adam ◽  
Jibrin Gambo ◽  
Edegbene A. Ovie

This study is aimed at assessing the ecological health condition of River Hadejia. The specific objectives are to; determine the monthly variation of the Physico-chemical parameters of River Hadejia. The physicochemical analysis carried out on the water samples are: pH, temperature, Electrical Conductivity, TDS, Turbidity, Nitrate, Phosphate, DO, BOD, Transparency, Depth and flow velocity which were determined by standard methods. The results of Physico-chemical parameters obtained were subjected to ANOVA using statistical package software, the mean conductivity values range between (104-127 μS/cm). Nitrate in this study ranged from 0.04–0.80 mg/l and Station 3 had the highest nitrate value. The mean turbidity values obtained from the water samples of River Hadejia ranges from 124.56±11.06-149.52±23.11. Moreover, the temperature of Hadejia River varied from 13ºC to 28ºC. The highest temperature was in November at Station 1 while the lowest was recorded in February at station 1 which may be due to cold weather of the morning time.


2020 ◽  
Author(s):  
Anna Tengia Kessy ◽  
George Chombe Msalale

Abstract Background: In most sub-Sahara African countries, herbal medicines are widely used during pregnancy or delivery for various motives despite their unclear pharmacology and potential toxicity. All risky exposures, including use of herbs during pregnancy or delivery should be restricted in order to facilitate achieving Sustainable Development Goal (SDG) 3, which states: “ensure healthy lives and promote wellbeing for all including reduction of morbidity and mortality among mothers and newborns”. Thus, this study assessed use of herbal medicines during pregnancy or delivery and determined factors associated with the practice in Tabora, Tanzania.Methods: This cross-sectional quantitative study gathered information from 340 women who delivered a live-born baby in the preceding two years. Using a two-stage-sampling technique, we selected and interviewed women attending reproductive, maternal and child health clinics in public health facilities in Tabora, central Tanzania. We compared proportions using chi-square test and performed Poisson regression analysis to determine independent correlates of herbal use.Results: Of 340 recruited women, 208 [61.2 %; 95% confidence interval (CI): 55.4, 66.3%] used herbal medicines during pregnancy or delivery. Major reasons for use included shortening of labour duration, 81 (38.9%) and reducing labour pain, 58 (27.9%). The independent predictors of herbal use were number of antenatal visits and the stance of maternity health care providers on the use of herbs. Women who made less than four visits had 24% higher prevalence ratio of using herbal medicines as compared to those who made at least four visits [adjusted Prevalence Ratio (aPR):1.24; 95%CI: 1.02, 1.50, p=0.03]. Furthermore, the adjusted prevalence ratio of using herbs was 35% higher among women who were not discouraged by health care providers against using herbs versus those who were discouraged (aPR: 1.35; 95%CI: 1.13, 1.60, p=0.01). Conclusions: Use of herbal medicines during pregnancy or delivery among women in Tanzania is high. This calls for comprehensive investigations on the effects of using herbs during pregnancy or delivery as a step towards understanding some of the challenges in achieving SDG 3. Additionally, maternity health care providers ought to strengthen provision of health education messages during antenatal visits on the undesirable effects of using herbs.


2020 ◽  
Vol 16 (1) ◽  
pp. 61-70
Author(s):  
O.U. Amaeze ◽  
O.A. Olugbake ◽  
M. Lawal

Background: Concurrent use of herbal and orthodox medicines can result in herb-drug interaction, which could remain unidentified due to the limited knowledge of health care providers on herbal medicines effects and safety.Objectives: This study aimed to assess the knowledge of medical and pharmacy students of the University of Lagos on herbal medicines and herb-drug interactions.Method: The study was a cross-sectional survey of final year pharmacy and medical undergraduate students (422) of the University of Lagos. Data was collected using a validated, previously developed, and standardized self-administered questionnaire. Descriptive statistics was used to evaluate the students’ demographics, knowledge of herbal medicines and herb-drug interactions, types and uses of herbal medicines, while inferential statistics was employed to assess the association between the students’ demographics and their knowledge of herb-drug interactions. Statistical significance was set at P<0.05.Results: The response rate was 97%. The students (98.0%) knew that herbs can be used as medicines; common uses of herbal medicines reported by the students include malaria (11.4%), pain (24.6%), and fever (36.2%). There was no association between the students’ demographics and their knowledge about herbal medicine. Age was significantly associated with knowledge of herb-drug interaction (P<0.05). The students (96.8%) knew that herbs can interact with conventional drugs when administered concurrently. The sources of the students’ knowledge about herbal medicine and herb-drug interaction include lectures (52.2%), literature (14%) and personal experience (13.9%).Conclusion: The students had good knowledge of herbal medicines; however, the subject of herbal medicines and their effects should be given more attention in the medical and pharmacy program curriculum, in order to enhance the students’ knowledge base of herbal medicines and interactions, and equip the future physicians and pharmacists adequately for better patient care. Keywords: Herbal medicines, Herb-drug interaction, Pharmacy students, Medical students


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