scholarly journals HIV and Glucose-6-Phosphate Dehydrogenase (G-6-PD) Deficiency among University Athletes in Rivers State, Nigeria

2020 ◽  
pp. 36-41
Author(s):  
I. O. Okonko ◽  
S. Adewuyi- Oseni ◽  
T. I. Cookey ◽  
K. C. Anugweje
Keyword(s):  
Cross Sectional Study ◽  
Quantitative Detection ◽  
P Value ◽  
Cross Sectional ◽  
Test Kit ◽  
Rivers State ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Age Range ◽  
Hiv 1 ◽  
University Athletes

Aim: Athletes are not immune to human immunodeficiency virus (HIV) and Glucose-6-Phosphate Dehydrogenase (G-6-PD) deficiency, and these conditions do not cause any harm or damage to their body as long as the necessary precautions in term of medications and others are adhered to. This research’s main objective was to determine the prevalence rate of G-6-PD deficiency and HIV among the University athletes in Rivers State, Nigeria. Study Design:  Cross-sectional study. Place and Duration of Study: Sports Institute, University of Port Harcourt (UNIPORT), Nigeria, between June 2012 and July 2015. Methods: A total of 258 athletes were screened (134 females and 124 males) for HIV and G-6-PD deficiency. The athletes’ ages, gender and dates of birth were obtained and recorded. The presence of the HIV-1 and HIV-2 antibody was detected using the Uni-Gold™ Recombigen® HIV-1/2 for the detection of HIV. While Beutler Semi-quantitative G-6-PD Test Kit (BSA-3000) was utilized for the quantitative detection of G-6-PD deficiency in whole blood. Results: Of the 258 athletes tested, 0.7% was G-6-PD deficient while 1.2% was positive for HIV. The G-6-PD deficient positive cases were found in the age range of 21-25 years while the higher prevalence of HIV was observed in the age range 31-35 years (4.8%), followed by 26-30 years (1.9%) and the least was observed in the age group 21-25 years (0.7%). Age and gender had no significant relationship with the positivity of the athletes to HIV and G-6-PD (p-value >0.05). Conclusion: This study confirms the presence of HIV and G-6-PD deficiency among university athletes in Rivers State, Nigeria. This calls for routine testing of both the athletes and the general public for G-6-PD deficiency to prevent hemolysis causes by G-6-PD deficiency.

Incidence and Pattern of Clinical Dengue Cases among Travelers and NonTravelers in a District of Bangladesh

2020 ◽  
Vol 7 (1) ◽  
pp. 3-7
Author(s):  
Syed Abdul Kader ◽  
Sonia Afrin Rob
Keyword(s):  
Endemic Area ◽  
Dengue Infection ◽  
Laboratory Data ◽  
Data Entry ◽  
Cross Sectional Study ◽  
P Value ◽  
College Hospital ◽  
Cross Sectional ◽  
Test Kit ◽  
Ns1 Antigen

Background: Expansion of Dengue fever caused by a mosquito borne arbovirus to new countries and, from urban to rural settings constitutes an important health problem in the world including Bangladesh. Objective: This study was conducted to evaluate spread of clinical Dengue to previously non-endemic Barisal district and get an idea of how recent this spread is by comparing proportions of non-travelers and travelers to an endemic area among the admitted patients. Methodology: The incidence of dengue infection in Barisal division with and without travel history to known endemic area was investigated in the current cross sectional study from a conveniently selected sample of patients admitted to the medicine department of Sher-e-Bangla medical College Hospital form Barisal district from July 15, through August, to September 15, 2019. Clinical and laboratory data were collected by attending doctors and checked by investigators. The primary diagnostic tool was NS1 antigen detected by SD Bioline Dengue NS1 Ag Test Kit. Data entry and analysis was done by SPSS version 24.0 software. Result: A total number of sample size was 212 admitted patents of whom 138(65.1%) were male, 74 (34.9 %) were female,116 (54.7%) of patients traveled to a known endemic zone, 96 (45.3%) did not; 206 (97.2%) were NS1 positive, 4 (1.9%) were IgM positive, 2 (0.9%) were IgM positive and IgG positive; Of travelling 116 patients, 92(79.3%) were male, 24(20.7%) were female, of travelling 96 patients 46(47.9%) were male, 50(52.1%) were female. p-value was <0.001. Conclusion: The study concluded that Dengue is becoming endemic in previously non-endemic zones like greater Barisal, though travelers still holds the major share of disease burden. Male preponderance in traveling to endemic zone was statistically significant. Bangladesh Journal of Infectious Diseases 2020;7(1):3-7

scholarly journals Pattern of earlobe attachment among the Ika ethnic group in Delta State, Nigeria

2021 ◽  
Vol 7 (3) ◽  
pp. 054-057
Author(s):  
Anibor Ese ◽  
Okolugbo Nekwu Emmanuel ◽  
Inikoro Charity ◽  
Odiete Enoh
Keyword(s):  
Ethnic Group ◽  
Frequency Distribution ◽  
Cross Sectional Study ◽  
Visual Observation ◽  
P Value ◽  
Cross Sectional ◽  
The Social ◽  
Age Variation ◽  
Sexual Category ◽  
Age Range

Objective: The aim of this study is investigating the distribution of earlobe attachment among the Ika ethnic group, in Delta State, Nigeria. Methods: This cross-sectional study was conducted in Ika speaking communities in Delta State, Nigeria. The sample consists of 384 subjects (192 males and 192 females) and the participants were categorized in accordance of sexual category with age ranges from 18 to 60 years. Data was collected by visual observation and the data obtained was analyzed with the aid of Statistical Package for the Social Sciences (SPSS) Version 21.0. A p-value less than 0.05 was considered as statistically significant. Results: The males portrayed the highest frequency distribution of attached earlobe while the females showed more of free earlobe. There is no significant gender difference in the pattern of earlobe attachment (p =.46). Free earlobe manifested among the 39-48years age range with the highest frequency distribution and the least by age interval within 59years and above. The attached earlobe displayed age differences in distribution with the highest frequency from 49-58 age range and the least by age range 59years and above. There is a remarkable age variation in earlobe attachment (p =.001). Conclusion: The attached earlobe is more predominant than the free or unattached earlobe among the Ikas in Delta State, Nigeria. The association between age and pattern of earlobe attachment is significant and there is no significant gender variation in the pattern of earlobe attachment.

scholarly journals Investigating Hysteroscopy Implementation in Infertile Women Candidate With a Normal Uterine Cavity for Laparoscopy in Hysterosalpingography

2018 ◽  
Vol 7 (1) ◽  
pp. 79-84
Author(s):  
Maliheh Amirian ◽  
Anis Darvish Mohammadabad ◽  
Negar Morovatdar ◽  
Leili Hafizi
Keyword(s):  
Diagnostic Laparoscopy ◽  
False Negative ◽  
Uterine Cavity ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Endometrial Polyps ◽  
Infertile Women ◽  
Submucous Myoma ◽  
Age Range

Objectives: Endometrial pathologies inside the cavity can occur simultaneously with gestational unpleasant consequences but are not always capable of being diagnosed by the hysterosalpingography (HSG). This study aimed to examine the value of performing diagnostic hysteroscopy beside diagnostic laparoscopy among infertile women with normal uterine cavities in HSG. Materials and Methods: A total of 103 infertile women with normal uterine cavities in the HSG and within the age range of 18-40 who referred to Imam Reza hospital for laparoscopy during 2016-2017 were included in this cross-sectional study. Hysteroscopy was performed simultaneously with diagnostic laparoscopy. Then, the existence of uterine pathologies like endometrial polyps, submucous myoma, and uterine endometrial adhesions and their relationship with the patient’s age, infertility type and duration, and cycle time were evaluated. A P value less than 0.05 was considered statistically significant. Results: Overall, 64 patients (63.1 %) had a normal uterine cavity in the hysteroscopy while 39 of them had an abnormal uterine cavity, the HSG false negative cases of whom were reported 37.9%. The pathologies found in the hysteroscopy were endometrial polyp (16 cases), submucous myoma (1 case), uterine septum (6 cases), asherman syndrome (7 cases), bicornuate uterus (4 cases), polyp + asherman (3 cases), polyp + submucous myoma (1 case), and septum + submucous myoma (1 case). Patients’ age, type of infertility, and menstruation time during performing hysteroscopy made no particular difference in diagnosing pathologies of the uterine cavity in the hysteroscopy. Conclusions: Based on the findings, conducting hysteroscopy in infertile women who are candidates of laparoscopy and have normal uterine cavities in HSG can result in recognizing some cases of uterine pathologies which influence the outcomes of future pregnancies is not dependent upon the patient’s age, menstruation time, type and duration of infertility, and result of laparoscopy.

scholarly journals Pattern and Prevalence of Color Vision Disorders amongst Secondary School Students in Rivers State, Nigeria

2019 ◽  
pp. 1-7
Author(s):  
Ibifubara N. Aprioku ◽  
Elizabeth A. Awoyesuku
Keyword(s):  
Secondary School ◽  
Color Vision ◽  
Secondary School Students ◽  
Cross Sectional Study ◽  
P Value ◽  
Vision Disorders ◽  
School Students ◽  
Cross Sectional ◽  
Ishihara Test ◽  
Rivers State

Aims: To determine the prevalence and pattern of color vision disorders (CVD) amongst secondary school students in Rivers State. Study Design: A community based descriptive cross sectional study. Place and Duration of Study: Department of Ophthalmology, University of Port Harcourt Teaching Hospital from the 20th of January to the 30th of April 2014. Methodology: A community based descriptive cross sectional study where study subjects were selected using multi-stage random sampling technique with inclusion criteria of consenting students with visual acuity >6/24. Ethical clearance for test was obtained from institution. Socio-demographic data obtained using an interviewer administered questionnaire. A comprehensive ocular examination was done and color vision assessed using the Ishihara 24 plate 2009 edition and the Farnsworth Munsell D 15 test for those who failed the Ishihara test. The prevalence of color vision disorder was determined by those that failed the Ishihara test. Data obtained was analyzed using SPSS version 21. Mean and standard deviations were determined for age. The age groups gender, other demographic distribution of the subjects amongst other was presented using frequency tables and charts. Statistical significance was put at p ≤ 0.05. Results: 1000 students were studied which consisted of four hundred and ninety five males (n=495; 49.4%) and five hundred and six females (n=506; 50.6%), with a male female ratio of 1:1.02. Mean age of subjects was 14.3±1.8 years with an age range of 9-20 years. The prevalence of color vision disorders was 2.8% (p-value 0.000) and was higher in males (2.1%) than females (0.7%) (P-value 0.000). Deutan defects were the most predominant (1.8%) compared to protan defects (0.4%) and tritan defects (0.2%). Conclusion: The study showed a prevalence of color vision disorders of 2.8% with male preponderance among secondary school students. Deutan color vision defects were most prevalent.

Seizure following acute hemolysis caused by Glucose-6-phosphate dehydrogenase Deficiency

2019 ◽  
Author(s):  
Bahram Darbandi ◽  
Simin Sajudi ◽  
Vahid Aminzadeh ◽  
Kioomars Golshekan ◽  
Afagh Hassanzadeh Rad ◽  
...  
Keyword(s):  
Drinking Water ◽  
G6pd Deficiency ◽  
Dehydrogenase Deficiency ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Exact Test ◽  
History Of ◽  
Glucose 6 Phosphate Dehydrogenase

Background: Storage of platelet concentrates (PCs) at room temperature (20-24°C) limits its storage time to 5 Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common inherited enzyme deficiency of the human red blood cells . Most of G6PD deficient individuals are asymptomatic, but acute hemolytic anemia may be presented with nausea, vomiting, abdominal pain, headache, jaundice, pallor, discoloration of the urine, chills, and fever. Seizure is reported as a rare symptom, as well. The present study aimed to investigate seizure following acute hemolysis caused by Glucose-6-phosphate dehydrogenase deficiency. Material and Methods:  This analytic cross-sectional study was conducted on all consecutive patients aged 1-12 years with G6PD deficiency hospitalized for hemolysis in 17 Shahrivar children hospital, Rasht, Iran, in 2016. Demographic characteristics and other variables such as place of inhabitants, type of drinking water, history of seizure in the patients and family, cause of hemolysis, hemoglobin level and hemoglobinuria on admission, and infection history prior to hemolysis were recorded. Data were analyzed by Mann-Whitney U test and Fischer Exact Test.  P-value < 0.05 indicated statistical significance and data were assessed by SPSS (version 20). Results:  The youngest patient was one year old and the oldest was 11 years old. Most of them were males (68.9%). Out of 244 patients, 8 ones (3.3%) experienced seizure. There was a significant correlation between seizure occurrence and family history of seizure (p=0.03) as well as fava bean consumption (p=0.019) as the causes of hemolysis; but not with infection as the cause of hemolysis, hemoglobin or hemoglobinuria level on admission, types of drinking water, place of living, and gender. Methemoglobinemia was considered as the main cause of the seizure. Conclusion: Although the rate of seizure was not so high (3.3%), it seems that seizure can be a critical and potentially life-threatening complication in these patients. Environmental factors may also play a role in the pathogenesis of the seizure in these patients.

Are MSM ready for Smartphone-based electronic readers in HIV Self-Testing? A cross-sectional study among Chinese MSM (Preprint)

2020 ◽  
Author(s):  
Gifty Marley ◽  
Gengfeng Fu ◽  
Ye Zhang ◽  
Jianjun Li ◽  
Joseph D Tucker ◽  
...  
Keyword(s):  
Online Survey ◽  
Statistical Significance ◽  
Anal Intercourse ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Self Testing ◽  
Test Kit ◽  
Electronic Readers

BACKGROUND The need for strategies to encourage user-initiated results reporting after HIV self-testing (HIVST) persists. Smartphone-based electronic readers have been shown capable of reading diagnostics results accurately in point-of-care diagnostics and could bridge gaps between HIVST and linkage to care. OBJECTIVE Our study aimed to assess the willingness of Chinese men who have sex with men (MSM) to use a smartphone-based electronic reader during HIVST through an online cross-sectional study. METHODS From February to April 2020, we conducted an online survey among Chinese MSM using a pretested structured questionnaire. Survey items were adapted from previous HIVST feasibility studies and modified as required. An online sample of men were recruited through social media platforms. Prior to answering reader related questions, participants watched a video on prototype smartphone-based electronic readers use. All data analysis was conducted using SPSS software 23.0.0. Statistical analysis conducted included descriptively analysis, chi-squared test and binary logistic regression. P-value <0.05 was deemed statistical significance. RESULTS Of 692 completed surveys, 53.3% (369) of participants were aged 26~40 years and 65.9% (456) of participants had ever self-tested for HIV. A total of 493/652 (71%) were willing to use a reader device. Among willing participants, 86.8% (428/493) would recommend it to their sexual partners, and 98% (483/493) agreed that having a smartphone-based electronic reader will increase their HIV testing frequency. 124 of 156 participants who had never used HIVST mentioned that this technology would motivate them to receive a first HIVST test kit. Being aged 26~40years (AOR=0.39, 95%CI=0.16-0.95), and predominantly playing receptive roles during anal intercourse increased likely to of being willing to use a reader (AOR=0.05, 95%CI=0.02-0.13). Also, MSM who engaged in unprotected anal intercourse (AOR=4.03, 95%CI=1.40-11.57) were four times more likely to be willing to use smartphone-based electronic readers than those who always used condoms. Majority of participants (73.5%, 447) preferred to purchase readers from local CDC offices and (51.2%, 311) were willing to pay less than 4.3USD for a reader device. CONCLUSIONS Many MSM were willing to use a smartphone-based electronic reader for HIV self testing. Prototypes are needed to further assess feasibility and usability. CLINICALTRIAL Not applicable

scholarly journals PATIENTS WITH SUICIDE ATTEMPT

2015 ◽  
Vol 22 (10) ◽  
pp. 1321-1326
Author(s):  
Jamil Junejo ◽  
Badaruddin Junejo ◽  
Inayatullah Awan ◽  
Asma Perveen
Keyword(s):  
Tertiary Care ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Family Issues ◽  
Younger Age ◽  
History Of ◽  
Age Range ◽  
Study Setting ◽  
Status Level

Objective: To determine the demographic details (gender, age, marital status,level of education, and occupation) of suicide attempters attending the tertiary care hospitalservices at Hyderabad, Pakistan. Study Design: Cross sectional study. Setting: Liaquat universityhospital Hyderabad and Sir Cowasjee Jahangir Institute of psychiatry (CIJP) Hyderabad.Period: Twelve months from the 1st January 2011 to 31st December 2011. Methodology:The aim of the study was. Patients with a history of attempted suicide. Two hundred (200)consecutive cases were recruited and selected according to the inclusion criteria. An informedconsent was obtained from patients for being included in the study. A specially designed semistructuredProforma was used to record demographic details of the patients. Data were enteredinto and analyzed through statistical software SPSS version 20. Results: Total 200 hundredcases were included in the study. Males 78.5 % (N=157) outnumbered female patients 21.5% (N= 43). The age range of study subjects was between 15 -59 years. Mean age of the totalcases was 22.6 years. Majority of the patients presenting with suicide were single comprising61 % (N= 122) of study cases with a P value < 0.001. Total cases of married subjects were 27.5% (N= 55) with a P value < 0.001. While 5.5% subjects were separated and 6 % were divorced.Unskilled labors made the largest group comprising of 24.5 % (N=49) of all the cases. Otheroccupations included farmers (15.5 %), skilled labor (15%), jobless (11.5%), house wives (8.5%), students (7 %), and shopkeepers (6%). Out of the total 200 patients with attempted suicide32% were illiterate, 33.5 % were educated up to primary level, 19.5% were matriculate, 09 %were intermediate passed, and only 6 % were graduate. (Table-II). Conclusion: In Pakistan stillSuicide attacks are reported. Our results suggest that suicidal thoughts can be entirely predictby common reported in male and younger age due to very sensitive to family issues, lowereducation level and major depression due to unemployment or low level earning of unskilledlabor occupation in the Pakistan population.

scholarly journals Maternal Diabetes: A Potential Risk Factor of Congenital Hearing Loss

2021 ◽  
Vol 55 (1) ◽  
Author(s):  
Angeli C. Carlos-Hiceta ◽  
Maria Rina T. Reyes-Quintos
Keyword(s):  
Incidence Rate ◽  
Otoacoustic Emissions ◽  
Maternal Diabetes ◽  
Cross Sectional Study ◽  
Hearing Screening ◽  
P Value ◽  
Cross Sectional ◽  
Diabetes Gestational ◽  
Age Range ◽  
Diabetic Mothers

Objective. The purpose of this study is to identify the incidence rate of 'refer' result in neonates born to diabetic mothers and to determine the association of maternal diabetes and the initial 'refer' result. Methods. This was a retrospective cross-sectional study which included neonates who had hearing screening test using transient-evoked otoacoustic emissions test (TEOAE) on both ears at the Philippine General Hospital Ear unit during three weeks. We obtained the demographic characteristics, presence/absence of maternal diabetes, and OAE results. Results. Among the 150 neonates, ten were born to diabetic mothers, with an age range of 2-8 days old. Forty percent of neonates of diabetic mothers had an initial 'refer' result compared with 7.9% of nondiabetic mothers' neonates. After logistic regression analysis, there is a significant association between maternal diabetes and initial 'refer' result in OAE with a p-value <0.05. If the mother is diagnosed with diabetes (gestational/pre-gestational), the odds of having an initial 'refer' result in the hearing screening is 2x higher. The odds can range from 2-43 times. Conclusion. The incidence rate of an initial 'refer' result in neonates of diabetic mothers is 40%. There is a significant association between maternal diabetes and the initial 'refer' result in the OAE test.

scholarly journals The Level of Keratoconus Awareness among the Saudi Population in Riyadh

2021 ◽  
pp. 47-53
Author(s):  
Turad Alkadi ◽  
Shahad Alruwaili ◽  
Shahd Al Mahfud ◽  
Fahad Alomair
Keyword(s):  
Saudi Arabia ◽  
Online Survey ◽  
Cross Sectional Study ◽  
P Value ◽  
Saudi Population ◽  
Cross Sectional ◽  
Study Population ◽  
Level Of Knowledge ◽  
High Level ◽  
Age Range

Aims: This study aims to reveal misconceptions about keratoconus, to assess the level of knowledge among Saudi nationals and to compare the level of awareness of keratoconus between affected and unaffected individuals. Methodology: A cross-sectional study was conducted through an online survey on a study population that consisted of Saudi nationals over the age of 18 from November until December 2020 in Riyadh, Saudi Arabia to assess the level of knowledge of keratoconus among the Saudi population. Results: Three hundred and ten responses were obtained, the age range of the participants was between 18 to 50 years oldof which 182 were females and 128 were males. Thirty percent of participants stated that they had acquired their knowledge of keratoconus from the internet, while 29% stated that they had no knowledge of keratoconus at all. The majority of the sample (38.4%) had a high level of knowledge about keratoconus, 31.3% had a moderate level of knowledge and 30.3% had a low level of knowledge. A significant correlation between the level of knowledge and the diagnosis of keratoconus was found, in which keratoconus patients had a higher level of knowledge (44.2%) (p value < .05). Moreover, males (60.1%) had a higher level of awareness compared to females (23.1%) (p value < .05). Age had no significant effect on the level of knowledge (p value > .05). Conclusion: The level of knowledge about keratoconus among the Saudi population in Riyadh is moderate to high. Keratoconus patients had a higher level of knowledge compared to unaffected participants. We recommend further assessment of the level of knowledge about keratoconus with a larger sample size in different provinces of the Kingdom of Saudi Arabia.

scholarly journals Socio-demographic and Obstetric Variations of T. gondii and HIV-1 Co-infection among Pregnant Women in Cameroon

2019 ◽  
pp. 1-11
Author(s):  
Lem Edith Abongwa ◽  
Alberic Signang ◽  
Sharon Tibi ◽  
Annabella Ngenwi
Keyword(s):  
Pregnant Women ◽  
Venous Blood ◽  
Rapid Test ◽  
Antibody Test ◽  
P Value ◽  
Infection Prevalence ◽  
Cross Sectional ◽  
Test Kit ◽  
Northwest Region ◽  
Hiv 1

Aim: This study, aimed to identify the seroprevalence of T. gondii and HIV-1 co-infection in pregnant women in the Northwest Region of Cameroon. Study Design:  This cross-sectional study was conducted among 606 pregnant women attending antenatal clinic in the Northwest region of Cameroon. Place and Duration of Study: This study was carried out at the Bamenda Regional Hospital from May 2017 to December 2017. Methodology: Venous blood samples were collected for the detection of anti-Toxoplasma antibodies using rapid test kits while HIV was determine using Alere Determine™HIV-1/2 test kit and OraQuick HIV 1/2 Rapid Antibody Test kit for confirmation. Data were analyzed using SPSS version 23 statistical package. P-value <0.05 was considered statistically significant. Results: The mean (SD) age was 27.3 (5.3) years. The prevalence of T. gondii and HIV-1 was 139 (22.9%) and 70(11.6%) respectively, while that of T. gondii and HIV-1 co-infection was 31(5.1%). With the exception of age group and gestational age that was significant (p<0.05) for HIV, socio-demographic and obstetrical characteristics of T. gondii, HIV-1 and T. gondii and HIV-1 co-infection prevalence did not show any significant differences (p>0.05). Conclusions: The high prevalence of T. gondii and HIV-1 co-infection seen in this study demonstrates the need for routine antenatal screening for both infections. In addition, data from this study will be useful in designing control and prevention strategies against these diseases. Furthermore, the result will also be used as baseline data for further research on T. gondii and HIV-1 co-infection.

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