scholarly journals Determining the Effectiveness of Different Reconstruction Method and Mandibular Implants for Fracture in the Mandible

2021 ◽  
pp. 237-257
Author(s):  
Maryam Hassannia ◽  
Sajad Ghorbanizadeh
Keyword(s):  
Gold Standard ◽  
Reliable Method ◽  
Malignant Tumors ◽  
Case Reports ◽  
Computer Software ◽  
Reconstruction Method ◽  
Inclusion Criteria ◽  
Complementary Technique ◽  
Fibular Flap ◽  
Review Study

Introduction: Every year, many people suffer from mandibular defects due to various reasons such as trauma or malignant tumors. Various techniques for reconstructing mandibular defects have always been considered by surgeons and maxillofacial specialists to select the best option and achieve the desired results for the patient. In this study, various articles and their techniques for reconstruction of mandibular defects were reviewed and their results were reported. Materials and Methods: The present study is a systematic review study in which the keywords implants, mandibular, trauma, reconstruction of the desired articles in two databases pubmed and science direct from January 1, 2010 to August 31, 2018 And were selected and then examined. Results: 33 articles met the inclusion criteria on which the final review was performed. 17 articles were clinical studies, 9 articles were case reports and 7 articles were reviews. In these 33 studies, various techniques were examined, including the use of free vascularized fibular flap, the use of computer software, and the prototyping technique. Conclusion: Among the existing methods, the use of free vascularized fibular flap has been approved as a widely used and reliable method in various studies, and many researchers believe that this technique is the gold standard for the reconstruction of mandibular defects. The use of computer software was also used as a complementary technique to improve surgical outcomes.

Terson sign:

2020 ◽  
Vol 2 (1) ◽  
pp. 38-43
Author(s):  
Luiz Severo Bem Junior ◽  
Gustavo De Souza Andrade ◽  
Joao Ribeiro Memória Júnior ◽  
Hildo Rocha Cirne de Azevedo Filho
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Early Recognition ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Case Reports ◽  
Clinical Status ◽  
Vitreous Hemorrhage ◽  
Anterior Communicating Artery ◽  
Inclusion Criteria ◽  
Relationship Of ◽  
The Relationship

Terson's sign (TS) is classically defined as vitreous hemorrhage associated with subarachnoid hemorrhage of aneurysmal origin, being an important predictor of severity, indicating greater morbidity and mortality when compared to patients without the sign. The objective of this study is to review the relationship of Terson syndrome/Terson sign with the prognosis of aneurysmal subarachnoid hemorrhage. A search for original articles, research and case reports was performed on the PubMed, Scielo, Cochrane and ScienceDirect platform, with the following descriptors: Terson sign and subarachnoid hemorrhage. Retrospective, prospective articles and case reports published in the last 5 years and which were in accordance with the established objective and inclusion criteria were selected. Ten (10) articles were selected, in which the available results show an unfavorable prognostic relationship of TS and subarachnoid hemorrhage, because these patients had a worse clinical status assessed on the Glasgow scales ≤ 8, Hunt & Hess > III, Fisher > 3, in addition to intracranial hypertension and location of the aneurysm in the anterior communicating artery complex. The early recognition of this condition described by Albert Terson in 1900 brought an important contribution to neurosurgery, being recognized until nowadays.

scholarly journals Local Chemotherapy as an Adjuvant Treatment in Unresectable Squamous Cell Carcinoma: What Do We Know So Far?

2021 ◽  
Vol 28 (4) ◽  
pp. 2317-2325
Author(s):  
Luigi Bennardo ◽  
Francesco Bennardo ◽  
Amerigo Giudice ◽  
Maria Passante ◽  
Stefano Dastoli ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Gold Standard ◽  
Systemic Chemotherapy ◽  
Standard Treatment ◽  
Case Reports ◽  
Case Series ◽  
Surgical Removal ◽  
Local Chemotherapy

Background: Squamous cell carcinoma (SCC) is one of the most common cancers involving skin and oral mucosa. Although this condition’s gold-standard treatment is the surgical removal of the lesions, the physician must propose alternative treatments in some cases due to the patient’s ineligibility for surgery. Among the available alternative therapies, local chemotherapy may represent an initial treatment in combination with radiotherapy or systemic chemotherapy due to the low frequency of side-effects and the lack of necessity for expensive devices. Methods: In this paper, we review all available literature in various databases (PubMed, Scopus-Embase, Web of Science), proposing local chemotherapy as a treatment for cutaneous and oral SCC. Exclusion criteria included ocular lesions (where topical treatments are common), non-English language, and non-human studies. Results: We included 14 studies in this review. The majority were case reports and case series describing the treatment of non-resectable localized SCC with either imiquimod or 5-fluorouracil. We also analyzed small studies proposing combination treatments. Almost all studies reported an excellent clinical outcome, with a low risk of relapses in time. Conclusions: Resection of the lesion remains the gold-standard treatment for SCC. When this approach is not feasible, local chemotherapy may represent a treatment alternative, and it may also be associated with radiotherapy or systemic chemotherapy.

scholarly journals Applicability of Moyers analysis in mixed dentition: A systematic review

2013 ◽  
Vol 18 (6) ◽  
pp. 100-105 ◽  
Author(s):  
Mariana de Aguiar Bulhões Galvão ◽  
Gladys Cristina Dominguez ◽  
Sérgio Thomaz Tormin ◽  
Alex Akamine ◽  
André Tortamano ◽  
...  
Keyword(s):  
Systematic Review ◽  
Literature Review ◽  
Clinical Case ◽  
Case Reports ◽  
Mixed Dentition ◽  
Inclusion Criteria ◽  
Exclusion Criteria ◽  
Theoretical Probability ◽  
Study Population ◽  
Mixed Dentition Analysis

INTRODUCTION: Moyers analysis is widely used for analyzing mixed dentition, however, the accuracy of its theoretical probability tables has been recently questioned. Taking into consideration the fact the mixed dentition analysis is of paramount importance to precisely determine the space needed for alignment of canines and premolars, this research aimed at objectively assessing in the literature such an important step for orthodontic diagnosis. METHODS: A computerized search involving articles published on PubMed and Lilacs between 1990 and September, 2011 was conducted in accordance with the method described in the Cochrane 5.1.0 handbook. RESULTS: The research resulted in a sample composed of 629 articles. The inclusion criteria were: Articles using the Moyers analysis with a sample greater or equal to 40 patients. Conversely, the exclusion criteria were: Dental casts of patients with syndromes or oral cleft, researches conducted with a literature review, only, or clinical case reports and researches conducted before 1990. For this systematic review, 19 articles were selected. CONCLUSION: Based on the literature available, we can conclude that the Moyers mixed dentition analysis must be carefully used, since the majority of the articles analyzed showed that the probability of 75% was not as accurate as expected, leading to the need of adapting the probability levels depending on the study population.

scholarly journals Primary Oral Malignant Melanoma: Two Case Reports and Review of Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Neeraj Sharma
Keyword(s):  
Malignant Melanoma ◽  
Early Detection ◽  
Oral Cavity ◽  
Tumor Size ◽  
Malignant Tumors ◽  
Case Reports ◽  
Review Of Literature ◽  
Oral Region ◽  
Rare Neoplasm ◽  
Oral Malignant Melanoma

Primary malignant melanoma of the oral cavity is a rare neoplasm. The tumors tend to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. The survival of patients with mucosal melanomas is less than for those with cutaneous melanomas. Tumor size and metastases are related to the prognosis of the disease. Early detection, therefore, is important.

scholarly journals Economia solidária, saúde mental e inclusão: uma revisão de literatura / Solidarity economy, mental health and inclusion: a literature review

2020 ◽  
Vol 4 (4) ◽  
pp. 674-687
Author(s):  
Ioneide De Oliveira Campos ◽  
Rafael Moraes Reis
Keyword(s):  
Mental Health ◽  
Web Of Science ◽  
Case Reports ◽  
Self Management ◽  
Review Of The Literature ◽  
Inclusion Criteria ◽  
Solidarity Economy ◽  
Collective Work ◽  
Qualitative Approaches ◽  
Salud Mental

A Economia Solidária é uma alternativa para inserção laboral de pessoas com transtornos mentais. Realizou-se uma revisão da literatura, com o propósito de conhecer o que tem sido publicado sobre Economia Solidária, inclusão e Saúde Mental, quais os objetivos e métodos de pesquisa, quem são os profissionais e populações-alvo e quais os resultados obtidos nos estudos. Foram considerados os seguintes critérios para a realização desse estudo: a importância da temática para o contexto da Saúde Mental e a identificação de pesquisas e relatos de experiência que informassem práticas em Saúde Mental e Economia Solidária. A revisão foi realizada nas bases: Web of Science, DOAJ, PubMed, SciElo e LILACS, sem restrições de ano. Os descritores utilizados foram “economia solidária”, “saúde mental” e “inclusão”. Vinte e nove (n=29) artigos foram encontrados e, após a aplicação dos critérios de inclusão, dez foram analisados na íntegra. Trinta e quatro (n=34) profissionais estiveram envolvidos nas pesquisas, sendo a Terapia Ocupacional, Enfermagem e Psicologia, as profissões que apareceram mais frequentemente.  Todos os estudos encontrados eram qualitativos e foram conduzidos no Brasil. A entrevista foi o método mais adotado. Os resultados dos estudos sinalizaram ganhos para aspectos intrínsecos dos usuários no que se refere a autogestão, expressão, empoderamento, e também extrínsecos, como a questão familiar e do trabalho coletivo. A revisão agregou conhecimento que permitem refletir sobre a importância da interdisciplinaridade, do trabalho colaborativo em rede, e sobre a necessidade de documentação das experiências em Economia Solidária no país. AbstractThe Solidarity Economy is an alternative for the labour inclusion of people with mental health. A review of the literature was conducted in order to know what has been published on the issue of Solidarity Economy, Inclusion and Mental Health, what are the objectives and research methods, who are the professionals and populations’ target, and the results identified in the research. We considered the following criteria: the importance of the issue in the mental health context and identification of studies and case reports which informed practice in Mental Health and Solidarity Economy. The search was done at the databases: Web of Science, DOAJ, PubMed, Scielo and LILACS, with no year restrictions. The descriptors used were "solidarity economy", "mental health" and "inclusion". Twenty-nine (n=29) were found and after the inclusion criteria filter, ten articles were analysed. Thirty-four (n=34) professionals were involved in the studies and the most were Occupational Therapy, Nursing and Psychology. All the studies found used qualitative approaches and were conducted in Brazil. The interview was the most adopted method for data collection. The results indicate outcomes for users' intrinsic aspects such as self-management, expression, empowerment, and also extrinsic, such as family and collective work. The review added knowledge to reflect about the interdisciplinary and collaborative network, and also on the documentation of experiences in Solidarity Economy in the country.Keywords: Mental health; Solidarity economy; Public policies; Inclusion; Research.ResumenLa Economía Solidaria es una alternativa para la inserción laboral de personas con trastornos mentales. Se realizó una revisión de la literatura, con el fin de conocer qué se ha publicado sobre Economía Solidaria, inclusión y Salud Mental, cuáles son los objetivos y métodos de investigación, quiénes son los profesionales y las poblaciones objetivo y cuáles son los resultados obtenidos. Se consideraron los siguientes criterios para realizar este estudio: la importancia del tema para el contexto de la salud mental y la identificación de informes de investigación y experiencia que informarían las prácticas con la Salud Mental y la Economía Solidaria. La revisión se realizó en las bases de datos: Web of Science, DOAJ, PubMed, Scielo y LILACS, sin restricciones de año. Los descriptores utilizados fueron "economía solidaria", "salud mental" e "inclusión". Veintinueve (n = 29) artículos fueron encontrados y, después de aplicar los criterios de inclusión, diez fueron analizados en su totalidad. Treinta y cuatro (n = 34) profesionales participaron en las investigaciones, siendo la Terapia Ocupacional, Enfermería y Psicología las profesiones que aparecieron con más frecuencia. Todos los estudios encontrados fueron cualitativos y se realizaron en Brasil. La entrevista fue el método más adoptado. Los resultados de los estudios señalaron ganancias para los aspectos intrínsecos de los usuarios, como la autogestión, la expresión, el empoderamiento y también los aspectos extrínsecos, como el tema del trabajo familiar y colectivo. La revisión agregó conocimiento que nos permite reflexionar sobre la importancia de la interdisciplinariedad, así como el trabajo en red colaborativo, y sobre la necesidad de documentar experiencias en Economía Solidaria en el país.Palabras clave: Salud mental; Economía solidaria; Políticas públicas; Inclusión; Investigación.      

scholarly journals Antiviral Treatment on Pregnancy with COVID-19 Infection : A Systematic Review

2021 ◽  
Vol 4 (2s) ◽  
pp. 78-85
Author(s):  
Tigor Peniel Simanjuntak ◽  
◽  
Angela Putri Kakerissa ◽  
Grady Ivan Kurniawan
Keyword(s):  
Systematic Review ◽  
Side Effects ◽  
Pregnant Women ◽  
Gestational Age ◽  
Treatment Duration ◽  
Case Reports ◽  
Antiviral Treatment ◽  
Inclusion Criteria ◽  
Duration Of Treatment ◽  
Retrospective Case

Abstract Objective to evaluate antiviral treatment, duration, and side effects on pregnant women based on gestational age and severity of COVID-19 infection. Method: a systematic review of antiviral treatment, duration, and side effects on pregnant women based on gestational age and severity of COVID-19 infection. Systematic review was conducted following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) Statement. Result 948 papers accessed through Pubmed, Scopus, Science Direct, Cohcrane, and other with keywords “Antiviral”, “Pregnancy” “Pregnant” “Coronavirus” “COVID-19” “SARS-CoV-2”. Duplicate papers were excluded (n=302), topics and abstracts that do not meet the criteria (n=612), and 25 papers that did not meet the inclusion criteria. 9 papers that meet the inclusion criteria (case reports and cohort retrospective case study) discussed 20 pregnant women with COVID-19 infection (16 moderate and severe cases received Remdesivir, 3 moderate and mild cases received Lopinavir-ritonavir combination, and 1 moderate case received Arbidol). Conclusion, remdesivir is an antiviral frequently used in pregnancy on trimester II and III with severe COVID-19 infection with a duration of treatment of 5-10 days. Remdesivir should be monitored because some show side effects of increasing liver function. Key word: Antiviral, Pregnant, COVID-19

scholarly journals Presence of Ebola Virus in Breast Milk and Its Risk of Transmission to Breastfeeding Infants: Synthesis of Evidence

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1036-1036
Author(s):  
Melisa Medina-Rivera ◽  
Elizabeth Centeno-Tablante ◽  
Julia Finkelstein ◽  
Juan Pablo Peña-Rosas ◽  
Maria Nieves Garcia-Casal ◽  
...  
Keyword(s):  
Breast Milk ◽  
Ebola Virus ◽  
Case Reports ◽  
Data Extraction ◽  
Inclusion Criteria ◽  
Rt Pcr ◽  
Breastfed Infants ◽  
Milk Samples ◽  
Funding Sources ◽  
Ebov Infection

Abstract Objectives This study aimed to synthesize evidence related to the presence in and transmission of the Ebola virus (EBOV) through breast milk to help inform global guidelines on infant feeding. Methods We conducted a comprehensive systematic search in international and regional databases to identify original studies describing women with suspected or confirmed EBOV infection intending to breastfeed or give breast milk to an infant. Studies documenting any breastfeeding woman who has been vaccinated or is suspected or confirmed of viral infection at any time during or after pregnancy were identified. Records were independently screened by two authors and after duplicate records were removed, studies that met the inclusion criteria were selected for data extraction. Results From a total of 24,473 non-duplicate studies, we found six case reports that included seven breastfeeding mothers with suspected or confirmed EBOV infection and their eight children (one mother with twins). EBOV was detected via RT-PCR and/or by culture in five out of six breast milk samples that were collected from the mothers. Five out of the seven breastfed infants were found positive for EBOV infection and all of the identified cases led to death. Conclusions Ebola virus was detected in 5 out of 6 breast milk samples analyzed. Since the virus has also been detected in tears, saliva, and sweat, it is not possible to conclude with certainty that the transmission was through breast milk. Prospective studies are needed in order to define the safety of feeding infants with breast milk from mothers infected with EBOV. Funding Sources Department of Nutrition and Food Safety, WHO.

scholarly journals Interrater reliability of the Saint-Anne Dargassies Scale in assessing the neurological patterns of healthy preterm newborns

2018 ◽  
Vol 18 (1) ◽  
pp. 103-112
Author(s):  
Carla Ismirna Santos Alves ◽  
João Gonçalves de Medeiros ◽  
Luciana Arruda Carriço ◽  
Nívia Maria Arraes ◽  
Roselene Ferreira de Alencar ◽  
...  
Keyword(s):  
Gold Standard ◽  
Interrater Reliability ◽  
Ultrasound Examination ◽  
High Reliability ◽  
Interrater Agreement ◽  
Neurological Deficits ◽  
Cranial Ultrasound ◽  
Inclusion Criteria ◽  
Group I ◽  
Preterm Newborns

Abstract Objectives: to assess the interrater reliability of the Saint-Anne Dargassies Scale in assessing neurological patterns of healthy preterm newborns. Methods: twenty preterm newborns met the inclusion criteria for participation in this prospective study. The neurologic examination was performed using the Saint-Anne Dargassies Scale, showing normal serial cranial ultrasound examination. In order to test the reliability, the study was structured as follows: group I (rater 1/physiotherapist; rater 2/neonatologist); group II (rater 3/physiotherapist; rater 4/child neurologist) and the gold standard (expert and professor in pediatric neurology). Results: high interrater agreement was observed between groups I - II compared with the gold standard in assessing postural pattern (p<0.01). Regarding the assessment ofprimitive reflexes, greater agreement was observed in the evaluation of palmar grasp reflex and Moro reflex (p< 0.01) for group I compared with the gold standard. An analysis of tone demonstrated heterogeneous agreement, without compromising the reliability of the scale. The probability of equality between measurements of head circumference in the two groups, compared with the gold standard, was observed. Conclusions: the Saint-Anne Dargassies Scale demonstrated high reliability and homogeneity with significant power of reproducibility and may be capable to identify preterm newborns suspected of having neurological deficits.

scholarly journals What Do We Know About Prevalence and Management of Intoxicated Women During Labor and Delivery?

2019 ◽  
Vol 6 ◽  
pp. 2333794X1989479 ◽  
Author(s):  
Elizabeth Schaff ◽  
Marcos Moreno ◽  
Katrina Foster ◽  
Marilyn G. Klug ◽  
Larry Burd
Keyword(s):  
Literature Review ◽  
Mortality Risk ◽  
Case Reports ◽  
Blood Alcohol Concentration ◽  
Alcohol Concentration ◽  
Blood Alcohol ◽  
Inclusion Criteria ◽  
Infant Deaths ◽  
Full Text Review ◽  
Infant Outcome

Objective. To review the published literature on women who were intoxicated at delivery and outcomes for their infants. Methods. A systematic literature review was utilized to identify articles meeting our inclusion criteria. After screening using titles and abstracts, we identified 34 articles requiring full-text review. Each of these were reviewed by at least 2 of the authors. We identified 12 articles that met our inclusion criteria. Results. We identified case reports of 16 mothers who delivered with a blood alcohol concentration (BAC) ranging from 42.1 to 473 mg/dL. Three of the pregnancies (18.8%) ended with a stillbirth, 5 (31.3%) were infant deaths, 6 (37.5%) lived, and 2 (12.5%) had no fetal or infant outcome reported. The BAC for the stillborn infants ranged from 120 to 460 mg/dL. The BAC among the infant deaths ranged from 96 to 715 mg/dL. Among surviving infants, the BAC ranged from 38.4 to 246.5 mg/dL. Conclusion. We identified no deaths with a BAC <96 mg/dL. However, it is not clear if this represents the lower level of BAC where mortality risk increases. In this article, we present 9 suggestions to improve detection and management of these mothers and their infants.

scholarly journals Spontaneous Tumors and Non-Neoplastic Proliferative Lesions in Pet Degus (Octodon degus)

2020 ◽  
Vol 7 (1) ◽  
pp. 32
Author(s):  
Tanja Švara ◽  
Mitja Gombač ◽  
Alessandro Poli ◽  
Jožko Račnik ◽  
Marko Zadravec
Keyword(s):  
Malignant Tumors ◽  
Single Case ◽  
Case Reports ◽  
Hepatocellular Adenoma ◽  
Benign Tumors ◽  
Malignant Neoplasms ◽  
Octodon Degus ◽  
Hind Limbs ◽  
Neoplastic Lesion ◽  
Veterinary Faculty

In recent years, degus (Octodon degus), rodents native to South America, have been becoming increasingly popular as pet animals. Data about neoplastic diseases in this species are still sparse and mainly limited to single-case reports. The aim of this study was to present neoplastic and non-neoplastic proliferative changes in 16/100 pet degus examined at the Veterinary Faculty University of Ljubljana from 2010 to 2015 and to describe the clinic-pathological features of these lesions. Twenty different lesions of the integumentary, musculoskeletal, genitourinary and gastrointestinal systems were diagnosed: amongst these were 13 malignant tumors, six benign tumors, and one non-neoplastic lesion. Cutaneous fibrosarcoma was the most common tumor (7/16 degus). It was detected more often in females (6/7 degus) and lesions were located mainly in hind limbs. The gastrointestinal tract was frequently affected, namely with two malignant neoplasms - an intestinal lymphoma and a mesenteric mesothelioma, four benign tumors – two biliary cystadenomas, an oral squamous papilloma and a hepatocellular adenoma, and a single non-neoplastic proliferative lesion. In one animal, two organic systems were involved in neoplastic lesions.

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