scholarly journals Clinical Manifestation of COVID-19 in General Age Group: A Review

2021 ◽  
pp. 263-269
Author(s):  
Shringarika Prakash
Keyword(s):  
Clinical Outcome ◽  
Clinical Manifestation ◽  
General Trend ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Vulnerable Groups ◽  
Age Group ◽  
Group A ◽  
Novel Coronavirus ◽  
Outcome After Infection

Background: COVID-19 is the disease caused by SARS-COV-2 or novel coronavirus. It is extremely contagious and has capability to produce severe clinical outcomes. Summary: Clinical manifestations of coronavirus disease 2019 or COVID-19 is different for different age groups. The general trend is that the chance of contraction and severe clinical outcome after infection increases with increase in age. The vulnerable section which is going through their immunosuppressive state must be cautious as they need to be protected more than any age group of the population. Conclusion: More study needs to be done to find out the vulnerable groups and nuances attached between COVID-19 and clinical manifestation in them.

scholarly journals A Systematic Review of the Clinical Studies in Humans for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2: Clinical Manifestation, Diagnosis and Clinical Trials

2021 ◽  
pp. 62-79
Author(s):  
Girum Tefera Belachew ◽  
Paramesh Hanumanthaiah ◽  
Fekede Meshesha Namo ◽  
Bitaniya Abera Tekelemariam
Keyword(s):  
Clinical Trials ◽  
Clinical Studies ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Treatment Protocol ◽  
Age Group ◽  
Objective Criterion ◽  
Systematic Analysis ◽  
Novel Coronavirus ◽  
Abstract Screening

Background: In December 2019 Chinese higher officials have acknowledged a number of cases of pneumonia happened in Wuhan, China with those patients who used the seafood from market selling live animals. At the end of December 2019, a kind of new pneumonia feast quickly in Wuhan, China, a novel coronavirus (2019-nCov). Objective: Systematic analysis of the completed clinical trials in humans due to coronavirus disease in 2019 between January 12, 2020, to May 30, 2020 in 11 countries and possibly to recommend the ways to overcome the COV-2 pandemic. Methods: Clinical studies completed in humans for the treatment of coronavirus disease in 2019 were looked for two databases, namely PubMed and Scopus. Based on the search terms, a total of 369 articles were downloaded. Of the total 369 articles, 38 duplicate articles were removed and 331 articles were screened with objective criterion. From the 331 articles, 168 articles were screened for excluded based on abstract screening and left with 163. Based on the exclusion criteria, 82 review articles, 51 articles not related to SARSCOV- 2 and 4 articles not written in English, in total 137 articles were excluded. Eventually, 26 articles were reviewed with required parameters for conclusive remarks. Results: Of all the completed human clinical trials conducted in 11 countries obtained from https://clinicaltrials.gov/, the total patients included in the clinical trials from January 12, 2020 to May 30, 2020 were 6130. Out of them 1060 (17.29%) were only females and the rest 5070 (82.71%) were both males and females. From all patients studied, 163 patients were 30-70 years old, 60 patients were 60 years old, 2531 patients were of all age groups and the rest 3376 patients were ≥ 18 years old. Of all the completed clinical trials in 11 countries, eight different interventional models and four study types were used. Conclusion: From the analysis of segregated results it is apparent that there was inclusion of patients with varied age group in the studies conducted with very less amount of patients from ≤ 18 years old, old age group and only females. The prime reason for least percentage inclusion of different age groups could be the weaker inherent immune response for the pandemic. COVID-19 can cause a conceivably deadly infection in humans. The most typical clinical manifestations reported by patients with coronavirus disease in 2019 were fever, cough, and expectoration. Approval of vaccines for control of COVID-19 is yet to be officially done, although now few vaccines are administered. Knowing the way to enter the cell and the mechanism on how to escape the immune system can be the potential targets to develop a novel SARS-COV-2 treatment protocol.

FEATURES OF THE COURSE AND TACTICS OF MANAGING CHILDREN WITH KIDNEYS AND URINARY TRACT DISEASES DURING THE PANDEMIC OF NEW CORONAVIRUS INFECTION COVID-19

2021 ◽  
Vol 100 (4) ◽  
pp. 74-79
Author(s):  
I.M. Kagantsov ◽  
◽  
V.V. Sizonov ◽  
V.G. Svarich ◽  
K.P. Piskunov ◽  
...  
Keyword(s):  
Age Groups ◽  
Clinical Manifestations ◽  
Routine Care ◽  
The Novel ◽  
Urinary System ◽  
Death Rates ◽  
Global Pandemic ◽  
Coronavirus Infection ◽  
Novel Coronavirus ◽  
Significant Health

The novel coronavirus infection (SARS-CoV-2), which first appeared in Wuhan, China in December 2019, has been declared a global pandemic by WHO. COVID-19 affects people of all age groups. The disease in children is usually asymptomatic or mild compared to adults, and with a significantly lower death rates. Data on kidney damage in children with COVID-19, as well as the effect of coronavirus infection on the course of diseases of the genitourinary system, are limited, the risks of contracting a new coronavirus infection in children with significant health problems, including those with chronic kidney disease, remain uncertain. The pandemic has affected the activities of surgeons treating diseases of the urinary system in children. Since the prospects for the end of the pandemic are vague, it is necessary to formulate criteria for selecting patients who can and should be provided with routine care in the pandemic. The purpose of this review is to highlight the features of the clinical manifestations and treatment of children with COVID-19, occurring against the background of previous renal pathology or complicating its course.

FC13-06 - The analysis of the reasons of suicide behaviour owing to family-sexual disharmonies

2011 ◽  
Vol 26 (S2) ◽  
pp. 1887-1887
Author(s):  
T. Butkova ◽  
N. Kibrik
Keyword(s):  
Suicide Attempts ◽  
Age Groups ◽  
Personal Characteristics ◽  
List Type ◽  
Age Group ◽  
Suicide Behaviour ◽  
Group A ◽  
Intimate Relations ◽  
Age Features ◽  
Somatic Diseases

ObjectiveFamily-sexual disharmonies - are the frequent reasons of suicide behaviour. Design: Complex inspection of 62 patients, in the age from 18 years has been performed. In the anamnesis patients had suicide behaviour owing to family-sexual disharmonies.Results1.Age when suicide attempts have been accomplished. Middle age has made 31 ± 8,8 years; 20–29 years - 43% (27 person); 30-39 years - 39% (24 person). The other 11 person-were included into the age groups of 40–49, 50–59 years.2.The reasons of autoaggressive behaviour: Suicide attempts owing to divorce, ideas of matrimonial incorrectness - 52% (32 person).Owing to the unfair attitude from the nearest environment or a dissatisfaction with behaviour and personal qualities of significant another - 48% (30 person). Age features: For young age - unavailability of young spouses to home life, absence of tolerance and respect to each other. Average age group - a dissatisfaction with behaviour of the partner. The senior age group - somatic diseases, loneliness, loss of relatives 3. In 66% of cases (41 person) suicide had no in the anamnesis of mental diseases at relatives.ConclusionsThe primary goal at rendering the psychotherapeutic help - revealing and correction of non adaptive installations of the person. Formation of confidential and empathic attitudes in family. It has been confirmed correlation analysis between partners′ satisfaction attitudes, personal characteristics suicident. It is necessary to raise availability of the information on various aspects of sexual health, psychohygiene of intimate relations.

Intrafascicular Injection of Ammonium Sulfate and Bupivacaine in Peripheral Nerves of Neonatal and Juvenile Rats

1998 ◽  
Vol 23 (2) ◽  
pp. 152-158 ◽  
Author(s):  
M. Catherine Hertl ◽  
Patricia K. Hagberg ◽  
Daniel A. Hunter ◽  
Susan E. Mackinnon ◽  
Jacob C. Langer
Keyword(s):  
Ammonium Sulfate ◽  
Peripheral Nerves ◽  
Animal Studies ◽  
Age Groups ◽  
Age Group ◽  
Nerve Blocks ◽  
Provide Pain Relief ◽  
Group A ◽  
Old Rats ◽  
Track Analysis

Background and ObjectivesRegional nerve blocks are often used for the treatment of postoperative pain in children. Ammonium sulfate is a non-narcotic anesthetic agent, which has been reported to provide pain relief lasting days to weeks, with few reported side effects in adult studies. Prior to considering clinical use in children, the neurotoxicity of ammonium sulfate in 4-day and 3-week old rats was assessed and compared with that of bupivacaine.MethodsEach rat received a posterior tibial nerve intrafascicular injection (0.01 mL in 4-day-old and 0.02 mL in 3-week-old rats) using either 10% ammonium sulfate (n = 24 per age group), 0.5% bupivacaine (n = 18 per age group), 0.9% saline (n = 18 per age group), or 5% phenol (n = 18 per age group). A functional assessment by serial walking track analysis and a morphologic assessment by neurohistology were made.ResultsNo abnormalities in serial walking track analysis and no structural nerve damage were detected after ammonium sulfate, bupivacaine, or saline injection. Bupivacaine caused mild focal changes in both age groups, which recovered by 8 weeks.ConclusionsIntrafascicular injection of ammonium sulfate was as safe as bupivacaine in this animal model. Further animal studies must be made before human trials are initiated.

scholarly journals POPULASI DAN PERILAKU KERA EKOR PANJANG (Macaca fascicularis) DI DESA PANCASARI SUKASADA BULELENG BALI

2018 ◽  
pp. 12
Author(s):  
Ni Putu Kiki Mahayuni ◽  
Ni Luh Watiniasih ◽  
Deny Suhernawan Yusup
Keyword(s):  
Daily Activity ◽  
Macaca Fascicularis ◽  
Sampling Method ◽  
Age Groups ◽  
Daily Activities ◽  
Age Group ◽  
Long Tail ◽  
Group A ◽  
Number Of Individuals ◽  
Daily Time

ABSTRACT Long-tailed macaque (Macacafascicularis) has its name as the length of its tail as long as its body. One of their habitats is located in Pancasari Village, Sukasada, Buleleng, Bali. Its current number and their daily activity has not been scientifically studied. This research, aimed to determine the number of individuals in its age groups, and the in daily activity as. The population was calculateemploying census methodand was distinguish accordingly to different age group (a) adult, (b) juveniles and (d) infant, ceusused three times that inthe morning at 09.00-10.00, during the day at 11.00-12.00and in the afternoon at 13.00-14.00. Daily activities of this macaque were recorded withanimal focal scan sampling method, twice in a day, in the morning at 09.00-11.00 and in the afternoon at 14.00-16.00 for 7 days. The population of long-tailed macaques in this are is 252, consisting of 96 adult male, 85 adult females, 44 juveniles and 27 infants. The long tail macaques at Pancasariuse most of their time for moving (30%), followed by eating (27%)and resting (22%). Only 2% of their daily time was used for aggressive and mating. Keywords: Macaca fascicularis, population, daily activities

scholarly journals Correlation Between Follicle Stimulating Hormone, Anti-Müllerian Hormone and Antral Follicle Count with Different Age Groups in Infertile Women

2021 ◽  
Vol 20 (1) ◽  
pp. 22-27
Author(s):  
Juthi Bhowmik ◽  
Parveen Fatima ◽  
Jesmine Banu ◽  
Farzana Deeba ◽  
Sheuli Chowdhury ◽  
...  
Keyword(s):  
Negative Correlation ◽  
Ovarian Reserve ◽  
Follicle Stimulating Hormone ◽  
Age Groups ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Age Group ◽  
Infertile Women ◽  
Group A ◽  
Study Population

Background: Reduced ovarian reserve predicts poor ovarian response and poor suc-- cess rates in infertile women who undergo Assisted Reproductive Technology (ART). Ovarian reserve decreases with age but the rate of decline varies from one woman to another. Follicle Stimulating Hormone (FSH) Anti-Müllerian Hormone (AMH) and antral follicle count (AFC) represent the three most frequently utilized laboratory tests in determining Ovarian Reserve (OR). To determine correlation between FSH, AMH and AFC in infertile female. Materials and methods: It was an observational (Cross sectional) study. This study was done in the Department of Reproductive Endocrinology and Infertility, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, between July 2018 to June 2019. The study population consisted of all the diagnosed female infertility patients of reproductive age. The women attending the study center during study period having primary or secondary infertility was considered as study population. They were divided in 4 age groups 21-25, 26-30, 31-35 yrs and 36-40 yrs years. Data was collected using a structured questionnaire following physical & lab examination. For D2 FSH level fasting blood was collected on D2/3 of menstrual cycle, serum FSH level was measured by ADVIA Centraur(R) XP immunoassay system. For S. AMH level blood sample was collected on 2nd day of cycle and measured by BECKMAN COULTER machine using Chemiluminescent Immunoassay method. For AFC count TVS was done on D2-5 of cycle using KONTRON medical USG machine. Collected data were classified, edited, coded and entered into the computer for statistical analysis by using SPSS version 23. Results: Out of 74 patients the mean age was found 32.6±5.5 years. Serum FSH, AMH and AFC were significantly associated with different age group. A negative correlation was found between serum FSH and serum AMH in all age group. But strong correlation found in age group 31-35 yrs and in 36-40 years age group. A negative correlation was found between serum FSH and total AFC in age group 26- 30 years, 31-35 years and 36-40 years respectively. A positive correlation was found between serum AMH and total AFC in all age group but most strong in age group 31-35 years. In multivariate logistic regression analysis serum AMH (<1.0 ng/ml) and total AFC (<5 number) were found to be significantly associated with age group >35 years patients. Conclusion: In all age grqoup, FSH, AMH and AFC correlates but it is more pronounced in advanced age that means >35 years age group. Chatt Maa Shi Hosp Med Coll J; Vol.20 (1); January 2021; Page 22-27

scholarly journals Morphological study of weight of the ovary at different age group in Bangladeshi people

1970 ◽  
Vol 10 (4) ◽  
pp. 266-268
Author(s):  
MS Ahmed ◽  
H Rahman ◽  
ZG Ara ◽  
SZ Sultana ◽  
M Rahman
Keyword(s):  
Morphological Study ◽  
Minimum Weight ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Age Group ◽  
Cross Sectional ◽  
Weight Variation ◽  
Group A ◽  
Group B ◽  
The Right

Aims: The morphological study was aimed to finedout the ovarian weight in dif ferent age group in Bangladeshi people to increase the knowledge regarding weight variation in our population. Subject & Methods: This cross - sectional study was carried out on Sixty two postmortem tissue contain ovary and fallopian tube along with surrounding structures were collected from 62- female cadaver of different age group by block dissection and fixed in 10% formal saline solution. Gross and fine dissections were carried out to see the morphological parameter of weight of the ovary in different age groups. In the present study, findings were compared with findings of the other researchers. Results: Maximum mean weight of the right ovary is found in this study in group C (46-80) years is 5.78gm and minimum weight is found in group A (2-13 years ) is 3.36gm .But incase left ovary Maximum in group B(14-45)years is 5.01 and minimum group a (2-13)is 2.72gm. statistatical analysis significant different between two groups was calculated by using students "T"Test. In the present study it is observed that the weight of the ovary is not equal on both side of same individual. Key words: ovary,morphology; weight DOI: http://dx.doi.org/10.3329/bjms.v10i4.9498 BJMS 2011; 10 (4): 266-268

scholarly journals Histological study of proportion of cortex and medulla of the ovary in Bangladeshi women

2016 ◽  
Vol 44 (1) ◽  
pp. 8-10
Author(s):  
Hosna Ara Perven ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Dilruba Siddiqua ◽  
Fatema Johora ◽  
Halima Afroz ◽  
...  
Keyword(s):  
Histological Study ◽  
Age Groups ◽  
Age Group ◽  
Cross Sectional ◽  
Medical College ◽  
Group A ◽  
The Mean ◽  
The Difference ◽  
Group B ◽  
The Right

This cross sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka from January to December 2009, to determine the proportion of cortex and medulla of the ovary in di_erent age group of Bangladeshi women. This study was based on collection of 140 ovaries of 70 unclaimed female dead bodies from the morgue of Dhaka Medical College, Dhaka. The samples were divided into three age-groups including A (10-13 years), B (14-45 years) & C (46-52 years). Histological slides were prepared by using routine haematoxylin and eosin stain. Ten best prepared histological slides from each age group were examined to determine the thickness of the cortex and medulla & proportion of the thickness of the cortex and the medulla of the ovary were expressed in percentages. The mean proportion of the cortex and the medulla of the right ovary were found 80.83±0.58% and 19.17±0.58% in group A, 86.95±1.14% and 13.05±1.14% in group B, 70.53±1.53% and 29.47±1.53% in group C respectively. The mean proportion of the cortex and the medulla of the left ovary were found 80.63±0.58% and 19.37±0.58% in group A, 86.78±1.14% and 13.22±1.14% in group B, 70.41±1.50% and 29.59±1.50% in group C respectively. The difference in mean proportion of the cortex and the medulla was not signi_cant in between the ovaries. However, the difference in mean proportion of the cortex and the medulla of the ovary between group A & group B, group A & group C and group B & group C were statistically significant.Bangladesh Med J. 2015 Jan; 44 (1): 8-10

scholarly journals Comparison of the clinical manifestations between different age groups of patients with overseas imported COVID-19

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243347
Author(s):  
Yujuan Han ◽  
Zujin Luo ◽  
Wenliang Zhai ◽  
Yue Zheng ◽  
Huan Liu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Clinical Symptoms ◽  
Demographic Data ◽  
Disease Onset ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Symptom Improvement ◽  
Group A ◽  
Group B

The current study investigated the clinical manifestations and outcomes of different age groups of patients with overseas imported COVID-19. In total, 53 COVID-19 patients admitted to the designated Beijing Xiaotangshan Hospital between March 16 and April 15 of 2020 were included. Based on the percentage of disease aggravation during hospital stay according to CT, the patients were divided into two groups: ≤40 years (group A; n = 41) and >40 years (group B; n = 12). The demographic data, epidemiological history, disease courses, potential complications, clinical symptoms, lab indices, chest CT outcomes, treatment protocols and turnovers of the two groups were compared. According to clinical typing, compared with group A, group B had a significantly greater proportion of the common type of COVID-19 (P<0.05) and greater comorbidity of type 2 diabetes (P<0.001). The two groups presented significantly different lab indices. Group B showed significantly more frequent CT abnormalities, with greater proportions of multiple lesions and bilateral lung involvement (P<0.05). During hospitalization, group B had a greater proportion of disease aggravation according to CT (P<0.01). Compared with group A, group B received a significantly greater proportion of antiviral therapy and presented a significantly greater occurrence of adverse drug reactions (P<0.05). The two groups did not significantly differ in time from admission to clinical symptom improvement or from disease onset to negative outcomes according to nucleic acid testing, the appearance of IgG or the appearance of IgM. They also did not significantly differ in length of stay. Older imported COVID-19 patients, particularly those with type 2 diabetes, showed a broader pulmonary extent and faster development of the disease, more severe pathogenetic conditions and a greater risk of developing a critically severe type. Increased attention should be given to this population in clinical practice.

Decreased Incidence of Type 1 Diabetes in Young Finnish Children

2020 ◽  
Author(s):  
Anna Parviainen ◽  
Anna But ◽  
Heli Siljander ◽  
Mikael Knip ◽  
the Finnish Pediatric Diabetes Register
Keyword(s):  
Type 1 Diabetes ◽  
Young Children ◽  
Age Groups ◽  
Incidence Rates ◽  
Islet Autoimmunity ◽  
Disease Rate ◽  
Age Group ◽  
Group A ◽  
Design And Methods

OBJECTIVE <p>The incidence of type 1 diabetes has been rising for decades, particularly among young children. Between 2006 and 2011 the incidence rate reached a plateau in Finland. In this observational register-based cohort study, we assess recent trends in the disease rate in Finnish children.</p> <p>RESEARCH DESIGN AND METHODS</p> <p>Based on data from the Finnish Pediatric Diabetes Register, we studied the incidence of type 1 diabetes among children under the age of 15 years between 2003 and 2018. We assessed sex-specific incidence rates (IRs) per 100,000 person years (PY) by 4-year time periods in three age groups (0.50–4.99, 5.00–9.99, and 10.00–14.99 years).</p> <p>RESULTS</p> <p>Among the 7,871 children with newly diagnosed type 1 diabetes, the median age at diagnosis increased from 7.88 to 8.33 (<i>P </i>= 0.001), while the overall IR decreased from 57.9/100,000 PY in 2003–2006 to 52.2/100,000 PY in 2015–2018, yielding an IR ratio (IRR) of 0.90 (95% CI 0.85–0.96, <i>P </i>= 0.001). This decline was mainly due to the decrease in the youngest age group [IRR 0.77 (95% CI 0.68–0.87); <i>P </i>< 0.001], being significant both among males and females. In the middle age group, a significant decrease was observed only among females. No changes were observed in the oldest children.</p> <p>CONCLUSIONS</p> <p>The incidence of type 1 diabetes decreased among young Finnish children between 2003 and 2018. Current findings imply that environmental factors driving the immune system towards islet autoimmunity are changing in young children.</p>

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