scholarly journals Cytotoxic Effect of Pterocarpus santalinus and stevia-based Mouthwash - A Lab-based Analysis

Author(s):  
R. Nandita ◽  
R. Priyadharshini ◽  
S. Rajeshkumar ◽  
P. Sinduja

Introduction: Red sandalwood called as Pterocarpus santalinus is esteemed for the rich red colour of its wood. Pterocarpus santalinus used as astringent, analgesic and anti-inflammatory agent. Also helpful in treating skin illness, fistula, haemorrhage and ulcers. Stevia rebaudina is a food additive with lingering flavor. The wood isn't aromatic. The tree isn't to be mistaken for the fragrant Santalum sandalwood trees that fill locally in South India. In the present study we have prepared Pterocarpus santalinus and stevia-based mouthwash and evaluated its cytotoxic activity. Materials and Methods: 1g of Pterocarpus santalinus and stevia were measured and 50 ml of distilled water were measured. Both were mixed together to make the aqueous extract. To that 10 nauplii were slowly added and the cytotoxic activity is analysed by the number of live nauplii counts.  Results: First day, Nauplii were grown in the medium and it hatches out after 24 hours. Second day, Mouthwash was added according to the concentration. Nauplii were collected and for each concentration 10 nauplii were added. After adding the nauplii, cytotoxicity well as undisturbed for one full day to analyze the inhibition of growth. Third day, nauplii were counted and cytotoxicity of mouthwash was evaluated. Statistical analysis showed significant reduction in the nauplii count (P<0.05).  Conclusion: Medicinal plants cure many severe diseases. Application of medicinal plants in the field of medicine should be improved. Based on the results recorded in the present study, it is concluded that Pterocarpus santalinus has a potential cytotoxicity activity. Hence the present study findings provide a beautiful base for some of the medicinal uses of Pterocarpus santalinus.

2015 ◽  
Vol 1 (01) ◽  
pp. 17-21
Author(s):  
P. Ethalsha Robert ◽  
A. Malar Retna

The present study evaluates in-vitro cytotoxic activity of active extracts of medicinal plants. It evaluates anti-cancer activity of most active extracts of I. pes-caprae and C. roseus. This study focuses on the total phenol content and the total flavanoid content of the plant and searches into its medicinal potency based on the total phenol and total flavanoid content. The anti-cancer activity of the extract is found to be more significant than one another.The cytotoxic activity of Ipomoea pes-caprae and C. roseus showed better results. Methanol extracts of aerial and root of Ipomoea pes-caprae possess maximum anticancer activity is found to be 61.77% and 65.55%. Chloroform extract of Catharanthus roseus root was also active against MCF- 7 cells by exhibiting 64.34% of activity. These plants may be a source of new antibiotic compounds.These findings enriches our knowledge of the chemical constituents that are responsible for the medicinal uses of the plant and the anti-cancer potential of selected plants.


PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6736 ◽  
Author(s):  
Silvia Catarino ◽  
Maria Cristina Duarte ◽  
Esperança Costa ◽  
Paula Garcia Carrero ◽  
Maria M. Romeiras

Leguminosae is an economically important family that contains a large number of medicinal plants, many of which are widely used in African traditional medicine. Angola holds a great socio-cultural diversity and is one of the richest floristic regions of the world, with over 900 native Leguminosae species. This study is the first to assess the medicinal uses of the legumes in Angola and provides new data to promote the conservation and the sustainable use of these unique resources. We document the ethnobotanical knowledge on Angola by reviewing the most important herbarium collections and literature, complemented by recent field surveys. Our results revealed that 127 native legume species have medicinal uses and 65% of them have other important uses by local populations. The species with most medicinal applications areErythrina abyssinica, Bauhinia thonningiiandPterocarpus angolensis. The rich flora found in Angola suggests an enormous potential for discovery of new drugs with therapeutic value. However, the overexploitation and the indiscriminate collection of legumes for multiple uses such as forage, food, timber and medical uses, increases the threats upon the native vegetation. Efforts to assess the conservation status of these species are urgently needed, and future actions should promote the sustainable use of medicinal plants in Angola together with the implementation of conservation strategies.


2017 ◽  
Vol 23 (2) ◽  
Author(s):  
JAMIL AHMED KHAN ◽  
RAJINDER PAUL

Poonch district of Jammu and Kashmir is a reservoir of enormous natural resources including the wealth of medicinal plants. The present paper deals with 12 medicinal plant species belonging to 8 genera of angiosperms used on pneumonia in cattle such as cows, sheep, goats and buffaloes in different areas of Poonch district. Due to poverty and nonavailability of modern health care facilities, the indigenous people of the area partially or fully depend on surrounding medicinal plants to cure the different ailments of their cattles. Further research on modern scientific line is necessary to improve their efficacy, safety and validation of the traditional knowledge.


Author(s):  
Monika Sahu ◽  
Vinod Kumar ◽  
Veenu Joshi

Diabetes Mellitus is the most prevalent metabolic disorder which has made it a major health threat worldwide. The available synthetic drugs for the cure of Diabetes mellitus are associated with high cost, various side effects and several limitations. Medicinal plants are the rich depots of the phytochemicals which can be useful for the treatment of chronic disorders. These plants are the better alternative to chemical drugs causing less or no harm to the body. Several plants are traditionally known for their antidiabetic properties but the detail investigation of their active molecules is required in order to be developed as therapeutic drug. Therefore, the present review aims to provide comprehensive information on various Indian medicinal plants, their constituents and mechanism of action for the cure of diabetes mellitus.


2018 ◽  
Vol 25 (1) ◽  
pp. 1-14
Author(s):  
Acharya Balkrishna ◽  
◽  
Anupam Srivastava ◽  
B.K. Shukla ◽  
Rajesh Kumar Mishra ◽  
...  

During plant exploration and survey of Morni Hills, Panchkula, Haryana (2017-2018) the authors collected about 2200 field numbers from different localities. Out of them, 323 species belonging to 251 genera and 92 families are medicinal plants. The information about medicinal properties of these plants has been gathered during field trips of Morni Hills from local vaidyas and local people of remote localities. The enumeration is alphabetically arranged, followed by their family names, local/common names, plant parts used for curing diseases and medicinal uses. These plant species are utilized by local people against various diseases in Morni Hills area.


Author(s):  
Dora Babu Neerugatti ◽  
Ganga Rao Battu ◽  
Raviteja Bandla

Objective: The current study is carried out to evaluate cytotoxicity activity of the methanolic extracts of some medicinal plants (Buchanania axillaris Desr, Tamilnadia ulignosa Retz, Phaseolus semierectus L and Stylosanthes fruticosa Retz).Methods: Cytotoxicity activity was evaluated on human cancer cell lines such as lung cancer (A549) and skin cancer (A431) using MTT assay method.Results: The selected plant extracts showed the dose-dependent cytotoxicity activity on the tested cell lines. The cytotoxicity variations on different cell lines were also observed for tested plants extracts. The cytotoxicity of the extracts was increased as the concentration of them was increased. Among all tested plants extracts Phaseolus semierectus showed the better cytotoxicity activity on tested cell lines.Conclusion: The results of the present study supported the folkloric usage of the studied plants and confirmed that the plant's extracts have the bioactive constituents with cytotoxic properties and their isolation can be useful for developing new anticancer drugs.


2015 ◽  
Vol 2 (2) ◽  
Author(s):  
Sher Wali Khan ◽  
Qamar Abbas ◽  
Syed Najmul Hassan ◽  
Hawas Khan ◽  
Azhar Hussain

This study was undertaken to enumerate the medicinal plants of the area, find out the conservation status, and record the folk knowledge from the inhabitants of Turmic Valley during 2011-2013. The valley is located in the Rondo division of the District Skardu on the Northeastern side of the Indus River. The detailed information about the local flora regarding medicinal uses was collected from the local herbal healers (Hakeems) and other knowledgeable people. Locally used herbs of the area prevent and cure the people from various diseases such as joint pains, bronchitis, flu and fever, lowering blood pressure, constipation, liver disorders, stomach and abdominal problems, etc. The most common medicinal herbs found in the region belong to the families Gentianaceae, Berberidaceae, Umbelliferae, Labiatae, Rosaceae, Compositae, Urticaceae, and Ranunculaceae. The inhabitants of the valley mostly use the 42 plant species for the treatment of different health problems. Forty-two species of plants (including 4 Gymnosperms, 1 monocotyledon, and 37 dicotyledons) and 35 types of diseases have been identified during the current study. Thymus linearis, Rosa webbiana, Urtica dioca, Pleurospermum candollei, Berberis spp., Delphinium brononianum, and Mentha angustifolia were the commonly used plant species in the valley. The collected baseline data of this study will be helpfulfor young researchers in the fieldof taxonomy, ethnobotany, pharmacology, organic chemistry, and particularly for biodiversity conservation. Over exploitation, habitat destruction, and over grazing are the major threats for the loss of the important flora of the area.


Author(s):  
BodaneArun Kumar

The present work is attempt has been made to compile the some ethno-medicinal plants and eco-friendly natural colors yielding flowering plants their preparations used for cure of diseases and information of flowering plants with the list of plants from B.S.N. Govt. P.G. College campus Shajapur, India. The present study focused on some important plants having medicinal uses and color yielding potential. Now-a-days natural products and herbal medicines have been recommended for the treatment of various diseases. The present study of ethno-medicinal and natural colors yielding flowering plants is helpful for local peoples of Shajapur.


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